Target Gene/Pathway💬 Info on mouse-over

No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	ABC transporters 💬	[1] ABCC8 💬	D00418 💬	Minoxidil	[1] 179 💬
2	Adrenergic signaling in cardiomyocytes 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
3	Adrenergic signaling in cardiomyocytes 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
4	AGE-RAGE signaling pathway in diabetic complications 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
5	AGE-RAGE signaling pathway in diabetic complications 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
6	Alcoholism 💬	[1] DRD2 💬	D00426 💬	Risperidone	[5]  8 , 156, 179, 187, 206 💬
7	Alcoholism 💬	[1] SLC6A3 💬	D01296 💬	Methylphenidate	[7]  6 , 13, 34, 84, 113, 179, 206 💬
8	Alcoholism 💬	[1] SLC6A3 💬	D04999 💬	Methylphenidate	[7]  6 , 13, 34, 84, 113, 179, 206 💬
9	Aldosterone synthesis and secretion 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
10	Aldosterone synthesis and secretion 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
11	Amphetamine addiction 💬	[1] SLC6A3 💬	D01296 💬	Methylphenidate	[7]  6 , 13, 34, 84, 113, 179, 206 💬
12	Amphetamine addiction 💬	[1] SLC6A3 💬	D04999 💬	Methylphenidate	[7]  6 , 13, 34, 84, 113, 179, 206 💬
13	Apelin signaling pathway 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
14	Apelin signaling pathway 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
15	Calcium signaling pathway 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
16	Calcium signaling pathway 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
17	Calcium signaling pathway 💬	[1] HTR2A 💬	D00426 💬	Risperidone	[5]  8 , 156, 179, 187, 206 💬
18	cAMP signaling pathway 💬	[1] DRD2 💬	D00426 💬	Risperidone	[5]  8 , 156, 179, 187, 206 💬
19	cGMP-PKG signaling pathway 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
20	cGMP-PKG signaling pathway 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
21	Cocaine addiction 💬	[1] DRD2 💬	D00426 💬	Risperidone	[5]  8 , 156, 179, 187, 206 💬
22	Cocaine addiction 💬	[1] SLC6A3 💬	D01296 💬	Methylphenidate	[7]  6 , 13, 34, 84, 113, 179, 206 💬
23	Cocaine addiction 💬	[1] SLC6A3 💬	D04999 💬	Methylphenidate	[7]  6 , 13, 34, 84, 113, 179, 206 💬
24	Coronavirus disease - COVID-19 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
25	Coronavirus disease - COVID-19 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
26	Cortisol synthesis and secretion 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
27	Cortisol synthesis and secretion 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
28	Cushing syndrome 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
29	Cushing syndrome 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
30	Diabetic cardiomyopathy 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
31	Diabetic cardiomyopathy 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
32	Dopaminergic synapse 💬	[1] DRD2 💬	D00426 💬	Risperidone	[5]  8 , 156, 179, 187, 206 💬
33	Dopaminergic synapse 💬	[1] SLC6A3 💬	D01296 💬	Methylphenidate	[7]  6 , 13, 34, 84, 113, 179, 206 💬
34	Dopaminergic synapse 💬	[1] SLC6A3 💬	D04999 💬	Methylphenidate	[7]  6 , 13, 34, 84, 113, 179, 206 💬
35	Gap junction 💬	[2] DRD2, HTR2A 💬	D00426 💬	Risperidone	[5]  8 , 156, 179, 187, 206 💬
36	GnRH secretion 💬	[1] KCNJ11 💬	D00418 💬	Minoxidil	[1] 179 💬
37	Inflammatory mediator regulation of TRP channels 💬	[1] HTR2A 💬	D00426 💬	Risperidone	[5]  8 , 156, 179, 187, 206 💬
38	Insulin secretion 💬	[2] ABCC8, KCNJ11 💬	D00418 💬	Minoxidil	[1] 179 💬
39	Neuroactive ligand-receptor interaction 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
40	Neuroactive ligand-receptor interaction 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
41	Neuroactive ligand-receptor interaction 💬	[2] DRD2, HTR2A 💬	D00426 💬	Risperidone	[5]  8 , 156, 179, 187, 206 💬
42	Parkinson disease 💬	[1] DRD2 💬	D00426 💬	Risperidone	[5]  8 , 156, 179, 187, 206 💬
43	Parkinson disease 💬	[1] SLC6A3 💬	D01296 💬	Methylphenidate	[7]  6 , 13, 34, 84, 113, 179, 206 💬
44	Parkinson disease 💬	[1] SLC6A3 💬	D04999 💬	Methylphenidate	[7]  6 , 13, 34, 84, 113, 179, 206 💬
45	Pathways in cancer 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
46	Pathways in cancer 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
47	Pathways of neurodegeneration - multiple diseases 💬	[1] SLC6A3 💬	D01296 💬	Methylphenidate	[7]  6 , 13, 34, 84, 113, 179, 206 💬
48	Pathways of neurodegeneration - multiple diseases 💬	[1] SLC6A3 💬	D04999 💬	Methylphenidate	[7]  6 , 13, 34, 84, 113, 179, 206 💬
49	Phospholipase D signaling pathway 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
50	Phospholipase D signaling pathway 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
51	Rap1 signaling pathway 💬	[1] DRD2 💬	D00426 💬	Risperidone	[5]  8 , 156, 179, 187, 206 💬
52	Renin secretion 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
53	Renin secretion 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
54	Renin-angiotensin system 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
55	Renin-angiotensin system 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
56	Serotonergic synapse 💬	[1] HTR2A 💬	D00426 💬	Risperidone	[5]  8 , 156, 179, 187, 206 💬
57	Serotonergic synapse 💬	[1] SLC6A4 💬	D00326 💬	Fluoxetine	[6] 13, 17, 78, 86, 179, 206 💬
58	Serotonergic synapse 💬	[1] SLC6A4 💬	D00823 💬	Fluoxetine	[6] 13, 17, 78, 86, 179, 206 💬
59	Synaptic vesicle cycle 💬	[2] SLC6A2, SLC6A3 💬	D01296 💬	Methylphenidate	[7]  6 , 13, 34, 84, 113, 179, 206 💬
60	Synaptic vesicle cycle 💬	[2] SLC6A2, SLC6A3 💬	D04999 💬	Methylphenidate	[7]  6 , 13, 34, 84, 113, 179, 206 💬
61	Synaptic vesicle cycle 💬	[1] SLC6A4 💬	D00326 💬	Fluoxetine	[6] 13, 17, 78, 86, 179, 206 💬
62	Synaptic vesicle cycle 💬	[1] SLC6A4 💬	D00823 💬	Fluoxetine	[6] 13, 17, 78, 86, 179, 206 💬
63	Type II diabetes mellitus 💬	[2] ABCC8, KCNJ11 💬	D00418 💬	Minoxidil	[1] 179 💬
64	Vascular smooth muscle contraction 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
65	Vascular smooth muscle contraction 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬

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