Target Gene/Pathway💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
1 | Acute myeloid leukemia 💬 15 genes, 25 drugs (DrugBank) and 59 diseases |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
2 | Acute myeloid leukemia 💬 15 genes, 25 drugs (DrugBank) and 59 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
3 | Acute myeloid leukemia 💬 15 genes, 25 drugs (DrugBank) and 59 diseases |
MPO [1] MPO 💬 |
D11684 D11684 💬 |
Verdiperstat | 002 [2] 2 , 17 💬 |
4 | Acute myeloid leukemia 💬 15 genes, 25 drugs (DrugBank) and 59 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
5 | Acute myeloid leukemia 💬 15 genes, 25 drugs (DrugBank) and 59 diseases |
PML [2] PML, RARA 💬 |
D00094 D00094 💬 |
Tretinoin | 002 [5] 2 , 63, 75, 94, 231 💬 |
6 | Adherens junction 💬 9 genes, 18 drugs (DrugBank) and 24 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
7 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
8 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
9 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
10 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
11 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
12 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D06623 D06623 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
13 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
ADRB2 [1] ADRB2 💬 |
D07713 D07713 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 |
14 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
KCNQ1 [1] KCNQ1 💬 |
D09569 D09569 💬 |
Ezogabine | 002 [2] 2 , 144 💬 |
15 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
SCN5A [1] SCN5A 💬 |
D00639 D00639 💬 |
Mexiletine | 001 [5] 1 , 2 , 10, 113, 114 💬 |
16 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
SCN5A [1] SCN5A 💬 |
D08215 D08215 💬 |
Mexiletine | 001 [5] 1 , 2 , 10, 113, 114 💬 |
17 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
SCN5A [1] SCN5A 💬 |
D00642 D00642 💬 |
Quinidine | 002 [3] 2 , 8 , 13 💬 |
18 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
SCN5A [1] SCN5A 💬 |
D00643 D00643 💬 |
Quinidine | 002 [3] 2 , 8 , 13 💬 |
19 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
SCN5A [1] SCN5A 💬 |
D02272 D02272 💬 |
Quinidine | 002 [3] 2 , 8 , 13 💬 |
20 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
SCN5A [1] SCN5A 💬 |
D08458 D08458 💬 |
Quinidine | 002 [3] 2 , 8 , 13 💬 |
21 | African trypanosomiasis 💬 7 genes, 19 drugs (DrugBank) and 57 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
22 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
23 | Alanine, aspartate and glutamate metabolism 💬 5 genes, 3 drugs (DrugBank) and 21 diseases |
ABAT [4] ABAT, ALDH5A1, GAD1, GAD2 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [16] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬 |
24 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
ADORA2A [1] ADORA2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
25 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
ADORA2A [1] ADORA2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
26 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
DDC [1] DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 002 [9] 2 , 4 , 6 , 13, 17, 90, 140, 164, 201 💬 |
27 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
DRD1 [2] DRD1, DRD2 💬 |
D09886 D09886 💬 |
Dexpramipexole | 002 [1] 2 💬 |
28 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
DRD1 [2] DRD1, DRD2 💬 |
D00059 D00059 💬 |
Levodopa | 002 [8] 2 , 4 , 6 , 17, 90, 140, 164, 201 💬 |
29 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
30 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
D06623 D06623 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
31 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
D00560 D00560 💬 |
Pimozide | 002 [1] 2 💬 |
32 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
D00559 D00559 💬 |
Pramipexole | 002 [2] 2 , 6 💬 |
33 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
D05575 D05575 💬 |
Pramipexole | 002 [2] 2 , 6 💬 |
34 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
D09953 D09953 💬 |
Pridopidine | 002 [3] 2 , 6 , 8 💬 |
35 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
D00784 D00784 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
36 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
D08489 D08489 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
37 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
D01226 D01226 💬 |
Sulpiride | 002 [5] 2 , 6 , 17, 46, 70 💬 |
38 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
D08549 D08549 💬 |
Sulpiride | 002 [5] 2 , 6 , 17, 46, 70 💬 |
39 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
40 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
41 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
42 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
43 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
44 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
45 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
46 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
47 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 [8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬 |
48 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
49 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
50 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
51 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
MAP2K1 [1] MAP2K1 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
52 | Aldosterone synthesis and secretion 💬 18 genes, 34 drugs (DrugBank) and 64 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [16] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬 |
53 | Aldosterone synthesis and secretion 💬 18 genes, 34 drugs (DrugBank) and 64 diseases |
MC2R [1] MC2R 💬 |
D00146 D00146 💬 |
Corticotropin | 002 [13] 2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬 |
54 | Aldosterone synthesis and secretion 💬 18 genes, 34 drugs (DrugBank) and 64 diseases |
PDE2A [1] PDE2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
55 | Aldosterone synthesis and secretion 💬 18 genes, 34 drugs (DrugBank) and 64 diseases |
PDE2A [1] PDE2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
56 | Allograft rejection 💬 30 genes, 22 drugs (DrugBank) and 57 diseases |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
57 | Allograft rejection 💬 30 genes, 22 drugs (DrugBank) and 57 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
58 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D00113 D00113 💬 |
Atropine | 002 [1] 2 💬 |
59 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D01077 D01077 💬 |
Atropine | 002 [1] 2 💬 |
60 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D02069 D02069 💬 |
Atropine | 002 [1] 2 💬 |
61 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D03011 D03011 💬 |
Atropine | 002 [1] 2 💬 |
62 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D03814 D03814 💬 |
Atropine | 002 [1] 2 💬 |
63 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D00138 D00138 💬 |
Scopolamine | 002 [1] 2 💬 |
64 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
65 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
66 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
67 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
68 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
69 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
70 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
71 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
72 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 [8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬 |
73 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
74 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
75 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
76 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
77 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
78 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
RTN4 [1] RTN4 💬 |
D10331 D10331 💬 |
Ozanezumab | 002 [1] 2 💬 |
79 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
80 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D00570 D00570 💬 |
Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬 |
81 | Amoebiasis 💬 17 genes, 25 drugs (DrugBank) and 62 diseases |
IL1R1 [2] IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
82 | Amoebiasis 💬 17 genes, 25 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
83 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
DDC [1] DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 002 [9] 2 , 4 , 6 , 13, 17, 90, 140, 164, 201 💬 |
84 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
DRD1 [1] DRD1 💬 |
D09886 D09886 💬 |
Dexpramipexole | 002 [1] 2 💬 |
85 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
DRD1 [1] DRD1 💬 |
D00059 D00059 💬 |
Levodopa | 002 [8] 2 , 4 , 6 , 17, 90, 140, 164, 201 💬 |
86 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
87 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D02696 D02696 💬 |
Talampanel | 002 [2] 2 , 6 💬 |
88 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 [8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬 |
89 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
90 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
91 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
92 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
93 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
94 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
95 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
96 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
97 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
98 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
99 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
100 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
101 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
102 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
ADRA1A [1] ADRA1A 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
103 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
ADRA1A [1] ADRA1A 💬 |
D06623 D06623 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
104 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
105 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
106 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
107 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
108 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
109 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
GRIA1 [2] GRIA1, GRIA2 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
110 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
GRIA1 [2] GRIA1, GRIA2 💬 |
D02696 D02696 💬 |
Talampanel | 002 [2] 2 , 6 💬 |
111 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
GRIA1 [7] GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 [8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬 |
112 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
113 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
114 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
115 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
116 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
117 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
GRIN1 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
118 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
GRIN1 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
119 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
GRIN1 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
120 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
121 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
122 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
123 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
124 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D00570 D00570 💬 |
Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬 |
125 | Antifolate resistance 💬 7 genes, 20 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
126 | Antigen processing and presentation 💬 23 genes, 15 drugs (DrugBank) and 53 diseases |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
127 | Antigen processing and presentation 💬 23 genes, 15 drugs (DrugBank) and 53 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
128 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
129 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
130 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PDE3B [1] PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
131 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PDE3B [1] PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
132 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PDE3B [1] PDE3B 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
133 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PDE3B [1] PDE3B 💬 |
D04720 D04720 💬 |
Levosimendan | 002 [1] 2 💬 |
134 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
135 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
136 | Apoptosis 💬 14 genes, 23 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
137 | Apoptosis 💬 14 genes, 23 drugs (DrugBank) and 54 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
138 | Arachidonic acid metabolism 💬 4 genes, 25 drugs (DrugBank) and 38 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
139 | Arginine and proline metabolism 💬 3 genes, 7 drugs (DrugBank) and 7 diseases |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
140 | Arginine and proline metabolism 💬 3 genes, 7 drugs (DrugBank) and 7 diseases |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
141 | Arginine and proline metabolism 💬 3 genes, 7 drugs (DrugBank) and 7 diseases |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
142 | Asthma 💬 21 genes, 21 drugs (DrugBank) and 55 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
143 | Asthma 💬 21 genes, 21 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
144 | Autoimmune thyroid disease 💬 41 genes, 14 drugs (DrugBank) and 37 diseases |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
145 | Autophagy - animal 💬 13 genes, 15 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
146 | Autophagy - animal 💬 13 genes, 15 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
147 | Autophagy - animal 💬 13 genes, 15 drugs (DrugBank) and 57 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
148 | Autophagy - animal 💬 13 genes, 15 drugs (DrugBank) and 57 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
149 | Autophagy - other 💬 1 gene, 3 drugs (DrugBank) and 41 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
150 | Axon guidance 💬 21 genes, 19 drugs (DrugBank) and 65 diseases |
ABL1 [2] ABL1, SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
151 | Axon guidance 💬 21 genes, 19 drugs (DrugBank) and 65 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
152 | Axon guidance 💬 21 genes, 19 drugs (DrugBank) and 65 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
153 | Axon guidance 💬 21 genes, 19 drugs (DrugBank) and 65 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [2] 2 , 51 💬 |
154 | B cell receptor signaling pathway 💬 16 genes, 19 drugs (DrugBank) and 63 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
155 | B cell receptor signaling pathway 💬 16 genes, 19 drugs (DrugBank) and 63 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
156 | B cell receptor signaling pathway 💬 16 genes, 19 drugs (DrugBank) and 63 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
157 | Bacterial invasion of epithelial cells 💬 5 genes, 6 drugs (DrugBank) and 12 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
158 | beta-Alanine metabolism 💬 4 genes, 3 drugs (DrugBank) and 19 diseases |
ABAT [3] ABAT, GAD1, GAD2 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [16] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬 |
159 | Bladder cancer 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
160 | Bladder cancer 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
161 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D00966 D00966 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
162 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
163 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
164 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
165 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
166 | Butanoate metabolism 💬 4 genes, 2 drugs (DrugBank) and 18 diseases |
ABAT [4] ABAT, ALDH5A1, GAD1, GAD2 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [16] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬 |
167 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
168 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
169 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
170 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
171 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
172 | Caffeine metabolism 💬 1 gene, 2 drugs (DrugBank) and 8 diseases |
XDH [1] XDH 💬 |
D01206 D01206 💬 |
Febuxostat | 002 [3] 2 , 6 , 13 💬 |
173 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADORA2A [2] ADORA2A, PDE1B 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
174 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADORA2A [2] ADORA2A, PDE1B 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
175 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADRA1A [8] ADRA1A, ADRA1B, ADRA1D, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
176 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADRA1A [8] ADRA1A, ADRA1B, ADRA1D, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬 |
D06623 D06623 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
177 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADRB2 [1] ADRB2 💬 |
D07713 D07713 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 |
178 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [16] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬 |
179 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
D00113 D00113 💬 |
Atropine | 002 [1] 2 💬 |
180 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
D01077 D01077 💬 |
Atropine | 002 [1] 2 💬 |
181 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
D02069 D02069 💬 |
Atropine | 002 [1] 2 💬 |
182 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
D03011 D03011 💬 |
Atropine | 002 [1] 2 💬 |
183 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
D03814 D03814 💬 |
Atropine | 002 [1] 2 💬 |
184 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
D00138 D00138 💬 |
Scopolamine | 002 [1] 2 💬 |
185 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
CYSLTR1 [1] CYSLTR1 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
186 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
DRD1 [2] DRD1, DRD5 💬 |
D09886 D09886 💬 |
Dexpramipexole | 002 [1] 2 💬 |
187 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
DRD1 [2] DRD1, DRD5 💬 |
D00059 D00059 💬 |
Levodopa | 002 [8] 2 , 4 , 6 , 17, 90, 140, 164, 201 💬 |
188 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
189 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
190 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
191 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
192 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
193 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
194 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
195 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
196 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 [8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬 |
197 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
HRH2 [1] HRH2 💬 |
D00295 D00295 💬 |
Cimetidine | 002 [1] 2 💬 |
198 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
HRH2 [1] HRH2 💬 |
D03503 D03503 💬 |
Cimetidine | 002 [1] 2 💬 |
199 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
HTR2A [3] HTR2A, HTR2B, HTR2C 💬 |
D00820 D00820 💬 |
Trazodone | 002 [1] 2 💬 |
200 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
HTR2A [3] HTR2A, HTR2B, HTR2C 💬 |
D08626 D08626 💬 |
Trazodone | 002 [1] 2 💬 |
201 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
202 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
203 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
TNNC2 [1] TNNC2 💬 |
D11363 D11363 💬 |
Reldesemtiv | 002 [2] 2 , 3 💬 |
204 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
ADORA1 [8] ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
205 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
ADORA1 [8] ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
206 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
ADRB2 [1] ADRB2 💬 |
D07713 D07713 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 |
207 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
D00113 D00113 💬 |
Atropine | 002 [1] 2 💬 |
208 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
D01077 D01077 💬 |
Atropine | 002 [1] 2 💬 |
209 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
D02069 D02069 💬 |
Atropine | 002 [1] 2 💬 |
210 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
D03011 D03011 💬 |
Atropine | 002 [1] 2 💬 |
211 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
D03814 D03814 💬 |
Atropine | 002 [1] 2 💬 |
212 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
D00138 D00138 💬 |
Scopolamine | 002 [1] 2 💬 |
213 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
DRD1 [3] DRD1, DRD2, DRD5 💬 |
D09886 D09886 💬 |
Dexpramipexole | 002 [1] 2 💬 |
214 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
DRD1 [3] DRD1, DRD2, DRD5 💬 |
D00059 D00059 💬 |
Levodopa | 002 [8] 2 , 4 , 6 , 17, 90, 140, 164, 201 💬 |
215 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
DRD2 [1] DRD2 💬 |
D00560 D00560 💬 |
Pimozide | 002 [1] 2 💬 |
216 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
DRD2 [1] DRD2 💬 |
D00559 D00559 💬 |
Pramipexole | 002 [2] 2 , 6 💬 |
217 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
DRD2 [1] DRD2 💬 |
D05575 D05575 💬 |
Pramipexole | 002 [2] 2 , 6 💬 |
218 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
DRD2 [1] DRD2 💬 |
D09953 D09953 💬 |
Pridopidine | 002 [3] 2 , 6 , 8 💬 |
219 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
DRD2 [1] DRD2 💬 |
D00784 D00784 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
220 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
DRD2 [1] DRD2 💬 |
D08489 D08489 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
221 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
DRD2 [1] DRD2 💬 |
D01226 D01226 💬 |
Sulpiride | 002 [5] 2 , 6 , 17, 46, 70 💬 |
222 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
DRD2 [1] DRD2 💬 |
D08549 D08549 💬 |
Sulpiride | 002 [5] 2 , 6 , 17, 46, 70 💬 |
223 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
DRD2 [2] DRD2, HTR6 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
224 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
DRD2 [2] DRD2, HTR6 💬 |
D06623 D06623 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
225 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
GABBR1 [2] GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 [5] 2 , 10, 13, 18, 149 💬 |
226 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
227 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D02696 D02696 💬 |
Talampanel | 002 [2] 2 , 6 💬 |
228 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 [8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬 |
229 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
230 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
231 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
232 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
233 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
234 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
235 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
236 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
237 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
238 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
MC2R [1] MC2R 💬 |
D00146 D00146 💬 |
Corticotropin | 002 [13] 2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬 |
239 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
D04720 D04720 💬 |
Levosimendan | 002 [1] 2 💬 |
240 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
PDE3A [6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
241 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [2] 2 , 51 💬 |
242 | Cell adhesion molecules 💬 32 genes, 19 drugs (DrugBank) and 37 diseases |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
243 | Cell cycle 💬 7 genes, 8 drugs (DrugBank) and 23 diseases |
ABL1 [1] ABL1 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
244 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
HLA-A [6] HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
245 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
246 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
247 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
248 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
249 | Central carbon metabolism in cancer 💬 18 genes, 24 drugs (DrugBank) and 55 diseases |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
250 | Central carbon metabolism in cancer 💬 18 genes, 24 drugs (DrugBank) and 55 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
251 | Central carbon metabolism in cancer 💬 18 genes, 24 drugs (DrugBank) and 55 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
252 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADORA1 [5] ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
253 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADORA1 [5] ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
254 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
255 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D06623 D06623 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
256 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D00514 D00514 💬 |
Dexmedetomidine | 002 [12] 2 , 4 , 6 , 21, 34, 46, 70, 113, 212, 215, 226, 280 💬 |
257 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D01205 D01205 💬 |
Dexmedetomidine | 002 [12] 2 , 4 , 6 , 21, 34, 46, 70, 113, 212, 215, 226, 280 💬 |
258 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D04375 D04375 💬 |
Guanabenz | 002 [2] 2 , 13 💬 |
259 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRB2 [1] ADRB2 💬 |
D07713 D07713 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 |
260 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
261 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
262 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
D04720 D04720 💬 |
Levosimendan | 002 [1] 2 💬 |
263 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
264 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
265 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [2] 2 , 51 💬 |
266 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
267 | Chemical carcinogenesis 💬 5 genes, 26 drugs (DrugBank) and 37 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
268 | Chemokine signaling pathway 💬 20 genes, 23 drugs (DrugBank) and 41 diseases |
MAP2K1 [1] MAP2K1 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
269 | Chemokine signaling pathway 💬 20 genes, 23 drugs (DrugBank) and 41 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [2] 2 , 51 💬 |
270 | Chemokine signaling pathway 💬 20 genes, 23 drugs (DrugBank) and 41 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
271 | Choline metabolism in cancer 💬 10 genes, 20 drugs (DrugBank) and 51 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
272 | Choline metabolism in cancer 💬 10 genes, 20 drugs (DrugBank) and 51 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
273 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00113 D00113 💬 |
Atropine | 002 [1] 2 💬 |
274 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D01077 D01077 💬 |
Atropine | 002 [1] 2 💬 |
275 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D02069 D02069 💬 |
Atropine | 002 [1] 2 💬 |
276 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D03011 D03011 💬 |
Atropine | 002 [1] 2 💬 |
277 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D03814 D03814 💬 |
Atropine | 002 [1] 2 💬 |
278 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00138 D00138 💬 |
Scopolamine | 002 [1] 2 💬 |
279 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
KCNQ1 [5] KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5 💬 |
D09569 D09569 💬 |
Ezogabine | 002 [2] 2 , 144 💬 |
280 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
MAP2K1 [1] MAP2K1 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
281 | Chronic myeloid leukemia 💬 14 genes, 15 drugs (DrugBank) and 28 diseases |
ABL1 [1] ABL1 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
282 | Chronic myeloid leukemia 💬 14 genes, 15 drugs (DrugBank) and 28 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
283 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [16] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬 |
284 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
285 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D02696 D02696 💬 |
Talampanel | 002 [2] 2 , 6 💬 |
286 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 [8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬 |
287 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
288 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
289 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
290 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
291 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
292 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
293 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
294 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
295 | Circadian rhythm 💬 2 genes, 1 drug (DrugBank) and 21 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
296 | Circadian rhythm 💬 2 genes, 1 drug (DrugBank) and 21 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
297 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
DDC [1] DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 002 [9] 2 , 4 , 6 , 13, 17, 90, 140, 164, 201 💬 |
298 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
DRD1 [2] DRD1, DRD2 💬 |
D09886 D09886 💬 |
Dexpramipexole | 002 [1] 2 💬 |
299 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
DRD1 [2] DRD1, DRD2 💬 |
D00059 D00059 💬 |
Levodopa | 002 [8] 2 , 4 , 6 , 17, 90, 140, 164, 201 💬 |
300 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
DRD2 [1] DRD2 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
301 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
DRD2 [1] DRD2 💬 |
D06623 D06623 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
302 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
DRD2 [1] DRD2 💬 |
D00560 D00560 💬 |
Pimozide | 002 [1] 2 💬 |
303 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
DRD2 [1] DRD2 💬 |
D00559 D00559 💬 |
Pramipexole | 002 [2] 2 , 6 💬 |
304 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
DRD2 [1] DRD2 💬 |
D05575 D05575 💬 |
Pramipexole | 002 [2] 2 , 6 💬 |
305 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
DRD2 [1] DRD2 💬 |
D09953 D09953 💬 |
Pridopidine | 002 [3] 2 , 6 , 8 💬 |
306 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
DRD2 [1] DRD2 💬 |
D00784 D00784 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
307 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
DRD2 [1] DRD2 💬 |
D08489 D08489 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
308 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
DRD2 [1] DRD2 💬 |
D01226 D01226 💬 |
Sulpiride | 002 [5] 2 , 6 , 17, 46, 70 💬 |
309 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
DRD2 [1] DRD2 💬 |
D08549 D08549 💬 |
Sulpiride | 002 [5] 2 , 6 , 17, 46, 70 💬 |
310 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
GRIA2 [1] GRIA2 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
311 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
GRIA2 [1] GRIA2 💬 |
D02696 D02696 💬 |
Talampanel | 002 [2] 2 , 6 💬 |
312 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
GRIA2 [6] GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 [8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬 |
313 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
314 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
315 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
316 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
317 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
318 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
319 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
320 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
321 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
322 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
323 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
324 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D00724 D00724 💬 |
Rabeprazole | 002 [2] 2 , 51 💬 |
325 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D08463 D08463 💬 |
Rabeprazole | 002 [2] 2 , 51 💬 |
326 | Colorectal cancer 💬 14 genes, 19 drugs (DrugBank) and 49 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
327 | Colorectal cancer 💬 14 genes, 19 drugs (DrugBank) and 49 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
328 | Complement and coagulation cascades 💬 15 genes, 24 drugs (DrugBank) and 42 diseases |
C5 [1] C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 [5] 2 , 11, 13, 62, 109 💬 |
329 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
C5 [1] C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 [5] 2 , 11, 13, 62, 109 💬 |
330 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
331 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
332 | Cortisol synthesis and secretion 💬 14 genes, 30 drugs (DrugBank) and 62 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [16] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬 |
333 | Cortisol synthesis and secretion 💬 14 genes, 30 drugs (DrugBank) and 62 diseases |
MC2R [1] MC2R 💬 |
D00146 D00146 💬 |
Corticotropin | 002 [13] 2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬 |
334 | Cushing syndrome 💬 21 genes, 43 drugs (DrugBank) and 66 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [16] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬 |
335 | Cushing syndrome 💬 21 genes, 43 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
336 | Cushing syndrome 💬 21 genes, 43 drugs (DrugBank) and 66 diseases |
MC2R [1] MC2R 💬 |
D00146 D00146 💬 |
Corticotropin | 002 [13] 2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬 |
337 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
CSF3R [1] CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 [33] 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
338 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
CSF3R [1] CSF3R 💬 |
D03247 D03247 💬 |
Lenograstim | 002 [7] 2 , 13, 16, 18, 19, 57, 65 💬 |
339 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
EPOR [1] EPOR 💬 |
D03231 D03231 💬 |
Erythropoietin | 002 [10] 2 , 6 , 13, 18, 22, 46, 47, 70, 95, 96 💬 |
340 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [20] 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
341 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IL1R1 [2] IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
342 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [7] 2 , 50, 65, 66, 97, 222, 228 💬 |
343 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
344 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
345 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
346 | Diabetic cardiomyopathy 💬 21 genes, 38 drugs (DrugBank) and 72 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
347 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
348 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
DDC [1] DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 002 [9] 2 , 4 , 6 , 13, 17, 90, 140, 164, 201 💬 |
349 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
DRD1 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 |
D09886 D09886 💬 |
Dexpramipexole | 002 [1] 2 💬 |
350 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
DRD1 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 |
D00059 D00059 💬 |
Levodopa | 002 [8] 2 , 4 , 6 , 17, 90, 140, 164, 201 💬 |
351 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
DRD2 [1] DRD2 💬 |
D09953 D09953 💬 |
Pridopidine | 002 [3] 2 , 6 , 8 💬 |
352 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
DRD2 [1] DRD2 💬 |
D01226 D01226 💬 |
Sulpiride | 002 [5] 2 , 6 , 17, 46, 70 💬 |
353 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
DRD2 [1] DRD2 💬 |
D08549 D08549 💬 |
Sulpiride | 002 [5] 2 , 6 , 17, 46, 70 💬 |
354 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
DRD2 [2] DRD2, DRD3 💬 |
D00560 D00560 💬 |
Pimozide | 002 [1] 2 💬 |
355 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
DRD2 [3] DRD2, DRD3, DRD4 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
356 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
DRD2 [3] DRD2, DRD3, DRD4 💬 |
D06623 D06623 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
357 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
DRD2 [3] DRD2, DRD3, DRD4 💬 |
D00559 D00559 💬 |
Pramipexole | 002 [2] 2 , 6 💬 |
358 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
DRD2 [3] DRD2, DRD3, DRD4 💬 |
D05575 D05575 💬 |
Pramipexole | 002 [2] 2 , 6 💬 |
359 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
DRD2 [3] DRD2, DRD3, DRD4 💬 |
D00784 D00784 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
360 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
DRD2 [3] DRD2, DRD3, DRD4 💬 |
D08489 D08489 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
361 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
362 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D02696 D02696 💬 |
Talampanel | 002 [2] 2 , 6 💬 |
363 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
GRIA1 [6] GRIA1, GRIA2, GRIA3, GRIA4, GRIN2A, GRIN2B 💬 |
D00775 D00775 💬 |
Riluzole | 002 [8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬 |
364 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
365 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
366 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
367 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
368 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
369 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
370 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
371 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
372 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
373 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
374 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
375 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
PPP3CA [3] PPP3CA, PPP3CB, PPP3CC 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
376 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
PPP3CA [3] PPP3CA, PPP3CB, PPP3CC 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
377 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
SCN1A [1] SCN1A 💬 |
D00639 D00639 💬 |
Mexiletine | 001 [5] 1 , 2 , 10, 113, 114 💬 |
378 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
SCN1A [1] SCN1A 💬 |
D08215 D08215 💬 |
Mexiletine | 001 [5] 1 , 2 , 10, 113, 114 💬 |
379 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
SCN1A [1] SCN1A 💬 |
D00642 D00642 💬 |
Quinidine | 002 [3] 2 , 8 , 13 💬 |
380 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
SCN1A [1] SCN1A 💬 |
D00643 D00643 💬 |
Quinidine | 002 [3] 2 , 8 , 13 💬 |
381 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
SCN1A [1] SCN1A 💬 |
D02272 D02272 💬 |
Quinidine | 002 [3] 2 , 8 , 13 💬 |
382 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
SCN1A [1] SCN1A 💬 |
D08458 D08458 💬 |
Quinidine | 002 [3] 2 , 8 , 13 💬 |
383 | Drug metabolism - cytochrome P450 💬 5 genes, 7 drugs (DrugBank) and 7 diseases |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
384 | Drug metabolism - cytochrome P450 💬 5 genes, 7 drugs (DrugBank) and 7 diseases |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
385 | Drug metabolism - cytochrome P450 💬 5 genes, 7 drugs (DrugBank) and 7 diseases |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
386 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 46 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D00752 D00752 💬 |
Mycophenolate mofetil | 002 [32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
387 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 46 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05094 D05094 💬 |
Mycophenolate mofetil | 002 [32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
388 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 46 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05095 D05095 💬 |
Mycophenolate mofetil | 002 [32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
389 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 46 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05096 D05096 💬 |
Mycophenolic acid | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 |
390 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 46 diseases |
MPO [1] MPO 💬 |
D11684 D11684 💬 |
Verdiperstat | 002 [2] 2 , 17 💬 |
391 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 46 diseases |
XDH [1] XDH 💬 |
D01206 D01206 💬 |
Febuxostat | 002 [3] 2 , 6 , 13 💬 |
392 | ECM-receptor interaction 💬 6 genes, 9 drugs (DrugBank) and 14 diseases |
SV2A [1] SV2A 💬 |
D00709 D00709 💬 |
Levetiracetam | 002 [4] 2 , 4 , 6 , 13 💬 |
393 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
394 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
395 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
396 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
397 | Endocrine and other factor-regulated calcium reabsorption 💬 7 genes, 25 drugs (DrugBank) and 49 diseases |
ESR1 [1] ESR1 💬 |
D00966 D00966 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
398 | Endocrine and other factor-regulated calcium reabsorption 💬 7 genes, 25 drugs (DrugBank) and 49 diseases |
ESR1 [1] ESR1 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
399 | Endocrine resistance 💬 19 genes, 37 drugs (DrugBank) and 59 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D00966 D00966 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
400 | Endocrine resistance 💬 19 genes, 37 drugs (DrugBank) and 59 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
401 | Endocrine resistance 💬 19 genes, 37 drugs (DrugBank) and 59 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
402 | Endocrine resistance 💬 19 genes, 37 drugs (DrugBank) and 59 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
403 | Endocrine resistance 💬 19 genes, 37 drugs (DrugBank) and 59 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
404 | Endocytosis 💬 20 genes, 27 drugs (DrugBank) and 50 diseases |
HLA-A [6] HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
405 | Endocytosis 💬 20 genes, 27 drugs (DrugBank) and 50 diseases |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [7] 2 , 50, 65, 66, 97, 222, 228 💬 |
406 | Endocytosis 💬 20 genes, 27 drugs (DrugBank) and 50 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
407 | Endocytosis 💬 20 genes, 27 drugs (DrugBank) and 50 diseases |
PML [1] PML 💬 |
D00094 D00094 💬 |
Tretinoin | 002 [5] 2 , 63, 75, 94, 231 💬 |
408 | Endocytosis 💬 20 genes, 27 drugs (DrugBank) and 50 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
409 | Endometrial cancer 💬 10 genes, 14 drugs (DrugBank) and 21 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
410 | Epithelial cell signaling in Helicobacter pylori infection 💬 11 genes, 15 drugs (DrugBank) and 21 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
411 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
412 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
413 | ErbB signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 51 diseases |
ABL1 [2] ABL1, SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
414 | ErbB signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 51 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
415 | ErbB signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 51 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
416 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D00966 D00966 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
417 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
418 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
GABBR1 [2] GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 [5] 2 , 10, 13, 18, 149 💬 |
419 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
420 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
RARA [1] RARA 💬 |
D00094 D00094 💬 |
Tretinoin | 002 [5] 2 , 63, 75, 94, 231 💬 |
421 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
422 | Fc epsilon RI signaling pathway 💬 19 genes, 35 drugs (DrugBank) and 59 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
423 | Fc epsilon RI signaling pathway 💬 19 genes, 35 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
424 | Fc gamma R-mediated phagocytosis 💬 8 genes, 8 drugs (DrugBank) and 13 diseases |
MAP2K1 [1] MAP2K1 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
425 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
IL1R1 [2] IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
426 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
427 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
428 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
429 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
430 | Focal adhesion 💬 26 genes, 37 drugs (DrugBank) and 42 diseases |
MAP2K1 [1] MAP2K1 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
431 | Focal adhesion 💬 26 genes, 37 drugs (DrugBank) and 42 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [2] 2 , 51 💬 |
432 | Focal adhesion 💬 26 genes, 37 drugs (DrugBank) and 42 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
433 | FoxO signaling pathway 💬 24 genes, 34 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
434 | FoxO signaling pathway 💬 24 genes, 34 drugs (DrugBank) and 53 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
435 | FoxO signaling pathway 💬 24 genes, 34 drugs (DrugBank) and 53 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
436 | GABAergic synapse 💬 28 genes, 37 drugs (DrugBank) and 54 diseases |
ABAT [3] ABAT, GAD1, GAD2 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [16] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬 |
437 | GABAergic synapse 💬 28 genes, 37 drugs (DrugBank) and 54 diseases |
GABBR1 [2] GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 [5] 2 , 10, 13, 18, 149 💬 |
438 | GABAergic synapse 💬 28 genes, 37 drugs (DrugBank) and 54 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
439 | GABAergic synapse 💬 28 genes, 37 drugs (DrugBank) and 54 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00696 D00696 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
440 | GABAergic synapse 💬 28 genes, 37 drugs (DrugBank) and 54 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D05028 D05028 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
441 | GABAergic synapse 💬 28 genes, 37 drugs (DrugBank) and 54 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
442 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
DRD1 [2] DRD1, DRD2 💬 |
D09886 D09886 💬 |
Dexpramipexole | 002 [1] 2 💬 |
443 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
DRD1 [2] DRD1, DRD2 💬 |
D00059 D00059 💬 |
Levodopa | 002 [8] 2 , 4 , 6 , 17, 90, 140, 164, 201 💬 |
444 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
DRD2 [1] DRD2 💬 |
D00560 D00560 💬 |
Pimozide | 002 [1] 2 💬 |
445 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
DRD2 [1] DRD2 💬 |
D00559 D00559 💬 |
Pramipexole | 002 [2] 2 , 6 💬 |
446 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
DRD2 [1] DRD2 💬 |
D05575 D05575 💬 |
Pramipexole | 002 [2] 2 , 6 💬 |
447 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
DRD2 [1] DRD2 💬 |
D09953 D09953 💬 |
Pridopidine | 002 [3] 2 , 6 , 8 💬 |
448 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
DRD2 [1] DRD2 💬 |
D00784 D00784 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
449 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
DRD2 [1] DRD2 💬 |
D08489 D08489 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
450 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
DRD2 [1] DRD2 💬 |
D01226 D01226 💬 |
Sulpiride | 002 [5] 2 , 6 , 17, 46, 70 💬 |
451 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
DRD2 [1] DRD2 💬 |
D08549 D08549 💬 |
Sulpiride | 002 [5] 2 , 6 , 17, 46, 70 💬 |
452 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
DRD2 [4] DRD2, HTR2A, HTR2B, HTR2C 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
453 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
DRD2 [4] DRD2, HTR2A, HTR2B, HTR2C 💬 |
D06623 D06623 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
454 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
HTR2A [3] HTR2A, HTR2B, HTR2C 💬 |
D00820 D00820 💬 |
Trazodone | 002 [1] 2 💬 |
455 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
HTR2A [3] HTR2A, HTR2B, HTR2C 💬 |
D08626 D08626 💬 |
Trazodone | 002 [1] 2 💬 |
456 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
457 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
458 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D00570 D00570 💬 |
Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬 |
459 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D00724 D00724 💬 |
Rabeprazole | 002 [2] 2 , 51 💬 |
460 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D08463 D08463 💬 |
Rabeprazole | 002 [2] 2 , 51 💬 |
461 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
CHRM3 [1] CHRM3 💬 |
D00113 D00113 💬 |
Atropine | 002 [1] 2 💬 |
462 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
CHRM3 [1] CHRM3 💬 |
D01077 D01077 💬 |
Atropine | 002 [1] 2 💬 |
463 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
CHRM3 [1] CHRM3 💬 |
D02069 D02069 💬 |
Atropine | 002 [1] 2 💬 |
464 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
CHRM3 [1] CHRM3 💬 |
D03011 D03011 💬 |
Atropine | 002 [1] 2 💬 |
465 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
CHRM3 [1] CHRM3 💬 |
D03814 D03814 💬 |
Atropine | 002 [1] 2 💬 |
466 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
CHRM3 [1] CHRM3 💬 |
D00138 D00138 💬 |
Scopolamine | 002 [1] 2 💬 |
467 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
HRH2 [1] HRH2 💬 |
D00295 D00295 💬 |
Cimetidine | 002 [1] 2 💬 |
468 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
HRH2 [1] HRH2 💬 |
D03503 D03503 💬 |
Cimetidine | 002 [1] 2 💬 |
469 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
KCNQ1 [1] KCNQ1 💬 |
D09569 D09569 💬 |
Ezogabine | 002 [2] 2 , 144 💬 |
470 | Gastric cancer 💬 20 genes, 29 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
471 | Gastric cancer 💬 20 genes, 29 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
472 | Gastric cancer 💬 20 genes, 29 drugs (DrugBank) and 57 diseases |
RARB [1] RARB 💬 |
D00094 D00094 💬 |
Tretinoin | 002 [5] 2 , 63, 75, 94, 231 💬 |
473 | Glioma 💬 12 genes, 24 drugs (DrugBank) and 56 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
474 | Glioma 💬 12 genes, 24 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
475 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PDE3B [1] PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
476 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PDE3B [1] PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
477 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PDE3B [1] PDE3B 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
478 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PDE3B [1] PDE3B 💬 |
D04720 D04720 💬 |
Levosimendan | 002 [1] 2 💬 |
479 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
480 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
481 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
482 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
483 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
484 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D02696 D02696 💬 |
Talampanel | 002 [2] 2 , 6 💬 |
485 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
GRIA1 [14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 [8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬 |
486 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
487 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
488 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
489 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
490 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
491 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
492 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
493 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
494 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
495 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
496 | Glycine, serine and threonine metabolism 💬 5 genes, 9 drugs (DrugBank) and 8 diseases |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
497 | Glycine, serine and threonine metabolism 💬 5 genes, 9 drugs (DrugBank) and 8 diseases |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
498 | Glycine, serine and threonine metabolism 💬 5 genes, 9 drugs (DrugBank) and 8 diseases |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
499 | GnRH secretion 💬 19 genes, 36 drugs (DrugBank) and 53 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [16] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬 |
500 | GnRH secretion 💬 19 genes, 36 drugs (DrugBank) and 53 diseases |
ESR2 [1] ESR2 💬 |
D00966 D00966 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
501 | GnRH secretion 💬 19 genes, 36 drugs (DrugBank) and 53 diseases |
ESR2 [1] ESR2 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
502 | GnRH secretion 💬 19 genes, 36 drugs (DrugBank) and 53 diseases |
GABBR1 [2] GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 [5] 2 , 10, 13, 18, 149 💬 |
503 | GnRH secretion 💬 19 genes, 36 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
504 | GnRH signaling pathway 💬 15 genes, 33 drugs (DrugBank) and 38 diseases |
GNRHR [1] GNRHR 💬 |
D00989 D00989 💬 |
Leuprolide | 001 [5] 1 , 2 , 3 , 51, 76 💬 |
505 | GnRH signaling pathway 💬 15 genes, 33 drugs (DrugBank) and 38 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
506 | GnRH signaling pathway 💬 15 genes, 33 drugs (DrugBank) and 38 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
507 | Graft-versus-host disease 💬 27 genes, 22 drugs (DrugBank) and 61 diseases |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
508 | Graft-versus-host disease 💬 27 genes, 22 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
509 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [20] 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
510 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
511 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
512 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
CSF3R [1] CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 [33] 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
513 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
CSF3R [1] CSF3R 💬 |
D03247 D03247 💬 |
Lenograstim | 002 [7] 2 , 13, 16, 18, 19, 57, 65 💬 |
514 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
EPOR [1] EPOR 💬 |
D03231 D03231 💬 |
Erythropoietin | 002 [10] 2 , 6 , 13, 18, 22, 46, 47, 70, 95, 96 💬 |
515 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
516 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
IL1R1 [2] IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
517 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
IL2RA [1] IL2RA 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
518 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [7] 2 , 50, 65, 66, 97, 222, 228 💬 |
519 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
520 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
521 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
522 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
523 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
524 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
525 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
526 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
527 | Hepatocellular carcinoma 💬 18 genes, 25 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
528 | Hepatocellular carcinoma 💬 18 genes, 25 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
529 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
C5 [1] C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 [5] 2 , 11, 13, 62, 109 💬 |
530 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
531 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
532 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
PML [1] PML 💬 |
D00094 D00094 💬 |
Tretinoin | 002 [5] 2 , 63, 75, 94, 231 💬 |
533 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
534 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
535 | HIF-1 signaling pathway 💬 20 genes, 40 drugs (DrugBank) and 73 diseases |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
536 | HIF-1 signaling pathway 💬 20 genes, 40 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
537 | HIF-1 signaling pathway 💬 20 genes, 40 drugs (DrugBank) and 73 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
538 | Histidine metabolism 💬 2 genes, 6 drugs (DrugBank) and 6 diseases |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
539 | Histidine metabolism 💬 2 genes, 6 drugs (DrugBank) and 6 diseases |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
540 | Histidine metabolism 💬 2 genes, 6 drugs (DrugBank) and 6 diseases |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
541 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
HLA-A [6] HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
542 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
543 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
544 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
545 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
546 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
547 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
548 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
549 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [2] 2 , 51 💬 |
550 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
551 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
552 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
HLA-A [6] HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
553 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
554 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
555 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
556 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
557 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
558 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
HLA-A [6] HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
559 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
560 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
561 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
562 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
563 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
564 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
IL1R1 [2] IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
565 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [7] 2 , 50, 65, 66, 97, 222, 228 💬 |
566 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
567 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
568 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
569 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
570 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
571 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
572 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D02696 D02696 💬 |
Talampanel | 002 [2] 2 , 6 💬 |
573 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
GRIA1 [6] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2B 💬 |
D00775 D00775 💬 |
Riluzole | 002 [8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬 |
574 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
GRIN1 [2] GRIN1, GRIN2B 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
575 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
GRIN1 [2] GRIN1, GRIN2B 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
576 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
GRIN1 [2] GRIN1, GRIN2B 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
577 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
GRIN1 [2] GRIN1, GRIN2B 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
578 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
GRIN1 [2] GRIN1, GRIN2B 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
579 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
GRIN1 [2] GRIN1, GRIN2B 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
580 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
GRIN1 [2] GRIN1, GRIN2B 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
581 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
GRIN1 [2] GRIN1, GRIN2B 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
582 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
583 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
584 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
585 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D00570 D00570 💬 |
Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬 |
586 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
587 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
588 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
589 | IL-17 signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
590 | IL-17 signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 79 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
591 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
592 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
IL2RG [1] IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
593 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
594 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
HRH1 [4] HRH1, HTR2A, HTR2B, HTR2C 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
595 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
HRH1 [4] HRH1, HTR2A, HTR2B, HTR2C 💬 |
D06623 D06623 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
596 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
HTR2A [3] HTR2A, HTR2B, HTR2C 💬 |
D00820 D00820 💬 |
Trazodone | 002 [1] 2 💬 |
597 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
HTR2A [3] HTR2A, HTR2B, HTR2C 💬 |
D08626 D08626 💬 |
Trazodone | 002 [1] 2 💬 |
598 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
599 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
600 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
TRPV1 [1] TRPV1 💬 |
D00250 D00250 💬 |
Capsaicin | 002 [5] 2 , 6 , 19, 86, 226 💬 |
601 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
602 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
603 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
PML [1] PML 💬 |
D00094 D00094 💬 |
Tretinoin | 002 [5] 2 , 63, 75, 94, 231 💬 |
604 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
605 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
606 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
607 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
608 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
609 | Insulin secretion 💬 13 genes, 40 drugs (DrugBank) and 43 diseases |
CHRM3 [1] CHRM3 💬 |
D00113 D00113 💬 |
Atropine | 002 [1] 2 💬 |
610 | Insulin secretion 💬 13 genes, 40 drugs (DrugBank) and 43 diseases |
CHRM3 [1] CHRM3 💬 |
D01077 D01077 💬 |
Atropine | 002 [1] 2 💬 |
611 | Insulin secretion 💬 13 genes, 40 drugs (DrugBank) and 43 diseases |
CHRM3 [1] CHRM3 💬 |
D02069 D02069 💬 |
Atropine | 002 [1] 2 💬 |
612 | Insulin secretion 💬 13 genes, 40 drugs (DrugBank) and 43 diseases |
CHRM3 [1] CHRM3 💬 |
D03011 D03011 💬 |
Atropine | 002 [1] 2 💬 |
613 | Insulin secretion 💬 13 genes, 40 drugs (DrugBank) and 43 diseases |
CHRM3 [1] CHRM3 💬 |
D03814 D03814 💬 |
Atropine | 002 [1] 2 💬 |
614 | Insulin secretion 💬 13 genes, 40 drugs (DrugBank) and 43 diseases |
CHRM3 [1] CHRM3 💬 |
D00138 D00138 💬 |
Scopolamine | 002 [1] 2 💬 |
615 | Insulin secretion 💬 13 genes, 40 drugs (DrugBank) and 43 diseases |
SNAP25 [1] SNAP25 💬 |
D02735 D02735 💬 |
Botulinum Toxin Type B | 002 [3] 2 , 6 , 51 💬 |
616 | Insulin secretion 💬 13 genes, 40 drugs (DrugBank) and 43 diseases |
SNAP25 [1] SNAP25 💬 |
D00783 D00783 💬 |
Botulinum toxin type A | 002 [13] 2 , 5 , 6 , 7 , 13, 15, 17, 36, 51, 70, 113, 149, 226 💬 |
617 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
618 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
619 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
PDE3B [1] PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
620 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
PDE3B [1] PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
621 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
PDE3B [1] PDE3B 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
622 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
PDE3B [1] PDE3B 💬 |
D04720 D04720 💬 |
Levosimendan | 002 [1] 2 💬 |
623 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
624 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
625 | Intestinal immune network for IgA production 💬 27 genes, 23 drugs (DrugBank) and 47 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
626 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
CSF3R [1] CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 [33] 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
627 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
CSF3R [1] CSF3R 💬 |
D03247 D03247 💬 |
Lenograstim | 002 [7] 2 , 13, 16, 18, 19, 57, 65 💬 |
628 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
EPOR [1] EPOR 💬 |
D03231 D03231 💬 |
Erythropoietin | 002 [10] 2 , 6 , 13, 18, 22, 46, 47, 70, 95, 96 💬 |
629 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [20] 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
630 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [7] 2 , 50, 65, 66, 97, 222, 228 💬 |
631 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
632 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
633 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
634 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
HLA-A [6] HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
635 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
636 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
637 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
638 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
639 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
640 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
641 | Legionellosis 💬 7 genes, 19 drugs (DrugBank) and 58 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
642 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
643 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
644 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
645 | Leukocyte transendothelial migration 💬 12 genes, 11 drugs (DrugBank) and 25 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [2] 2 , 51 💬 |
646 | Long-term depression 💬 12 genes, 15 drugs (DrugBank) and 29 diseases |
GRIA1 [3] GRIA1, GRIA2, GRIA3 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
647 | Long-term depression 💬 12 genes, 15 drugs (DrugBank) and 29 diseases |
GRIA1 [3] GRIA1, GRIA2, GRIA3 💬 |
D00775 D00775 💬 |
Riluzole | 002 [8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬 |
648 | Long-term depression 💬 12 genes, 15 drugs (DrugBank) and 29 diseases |
GRIA1 [3] GRIA1, GRIA2, GRIA3 💬 |
D02696 D02696 💬 |
Talampanel | 002 [2] 2 , 6 💬 |
649 | Long-term depression 💬 12 genes, 15 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
650 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
GRIA1 [2] GRIA1, GRIA2 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
651 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
GRIA1 [2] GRIA1, GRIA2 💬 |
D02696 D02696 💬 |
Talampanel | 002 [2] 2 , 6 💬 |
652 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
GRIA1 [7] GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 [8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬 |
653 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
654 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
655 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
656 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
657 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
658 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
659 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
660 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
661 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
662 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
663 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
664 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
665 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
666 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
667 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
668 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
669 | Longevity regulating pathway - multiple species 💬 10 genes, 13 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
670 | Longevity regulating pathway - multiple species 💬 10 genes, 13 drugs (DrugBank) and 56 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
671 | Longevity regulating pathway - multiple species 💬 10 genes, 13 drugs (DrugBank) and 56 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
672 | Malaria 💬 14 genes, 25 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
673 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [16] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬 |
674 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
675 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
676 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
677 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
678 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
679 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
680 | Measles 💬 36 genes, 37 drugs (DrugBank) and 49 diseases |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [7] 2 , 50, 65, 66, 97, 222, 228 💬 |
681 | Measles 💬 36 genes, 37 drugs (DrugBank) and 49 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
682 | Melanogenesis 💬 5 genes, 11 drugs (DrugBank) and 25 diseases |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
683 | Melanogenesis 💬 5 genes, 11 drugs (DrugBank) and 25 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
684 | Melanoma 💬 13 genes, 23 drugs (DrugBank) and 34 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
685 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
ABAT [4] ABAT, ALDH5A1, GAD1, GAD2 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [16] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬 |
686 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D00724 D00724 💬 |
Rabeprazole | 002 [2] 2 , 51 💬 |
687 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D08463 D08463 💬 |
Rabeprazole | 002 [2] 2 , 51 💬 |
688 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
DDC [1] DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 002 [9] 2 , 4 , 6 , 13, 17, 90, 140, 164, 201 💬 |
689 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D00752 D00752 💬 |
Mycophenolate mofetil | 002 [32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
690 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05094 D05094 💬 |
Mycophenolate mofetil | 002 [32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
691 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05095 D05095 💬 |
Mycophenolate mofetil | 002 [32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
692 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05096 D05096 💬 |
Mycophenolic acid | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 |
693 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
694 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
695 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
696 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PDE1B [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
697 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PDE1B [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
698 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
D04720 D04720 💬 |
Levosimendan | 002 [1] 2 💬 |
699 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PDE3A [6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
700 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
701 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
XDH [1] XDH 💬 |
D01206 D01206 💬 |
Febuxostat | 002 [3] 2 , 6 , 13 💬 |
702 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
ABL1 [1] ABL1 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
703 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
704 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
705 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
706 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
ROCK1 [1] ROCK1 💬 |
D07941 D07941 💬 |
Fasudil | 002 [2] 2 , 51 💬 |
707 | Mitophagy - animal 💬 1 gene, 3 drugs (DrugBank) and 7 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
708 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
ADORA1 [9] ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
709 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
ADORA1 [9] ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
710 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
DRD1 [1] DRD1 💬 |
D09886 D09886 💬 |
Dexpramipexole | 002 [1] 2 💬 |
711 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
DRD1 [1] DRD1 💬 |
D00059 D00059 💬 |
Levodopa | 002 [8] 2 , 4 , 6 , 17, 90, 140, 164, 201 💬 |
712 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
GABBR1 [2] GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 [5] 2 , 10, 13, 18, 149 💬 |
713 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
714 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00696 D00696 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
715 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D05028 D05028 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
716 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
D04720 D04720 💬 |
Levosimendan | 002 [1] 2 💬 |
717 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
PDE3A [6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
718 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
719 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
720 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
721 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
722 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
723 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
HLA-A [5] HLA-A, HLA-B, HLA-C, HLA-E, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
724 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
725 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
726 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
727 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
728 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
729 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADORA1 [2] ADORA1, ADORA2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
730 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADORA1 [2] ADORA1, ADORA2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
731 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRA1A [11] ADRA1A, ADRA1B, ADRA1D, DRD2, DRD3, DRD4, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
732 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRA1A [11] ADRA1A, ADRA1B, ADRA1D, DRD2, DRD3, DRD4, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬 |
D06623 D06623 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
733 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D00514 D00514 💬 |
Dexmedetomidine | 002 [12] 2 , 4 , 6 , 21, 34, 46, 70, 113, 212, 215, 226, 280 💬 |
734 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D01205 D01205 💬 |
Dexmedetomidine | 002 [12] 2 , 4 , 6 , 21, 34, 46, 70, 113, 212, 215, 226, 280 💬 |
735 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D04375 D04375 💬 |
Guanabenz | 002 [2] 2 , 13 💬 |
736 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRB2 [1] ADRB2 💬 |
D07713 D07713 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 |
737 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
C5 [1] C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 [5] 2 , 11, 13, 62, 109 💬 |
738 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00113 D00113 💬 |
Atropine | 002 [1] 2 💬 |
739 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D01077 D01077 💬 |
Atropine | 002 [1] 2 💬 |
740 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D02069 D02069 💬 |
Atropine | 002 [1] 2 💬 |
741 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D03011 D03011 💬 |
Atropine | 002 [1] 2 💬 |
742 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D03814 D03814 💬 |
Atropine | 002 [1] 2 💬 |
743 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00138 D00138 💬 |
Scopolamine | 002 [1] 2 💬 |
744 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
CNR1 [2] CNR1, CNR2 💬 |
D10915 D10915 💬 |
Cannabidiol | 002 [19] 2 , 6 , 8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 |
745 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
CNR1 [2] CNR1, CNR2 💬 |
D00306 D00306 💬 |
Dronabinol | 002 [7] 2 , 8 , 13, 46, 96, 271, 298 💬 |
746 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
CYSLTR1 [2] CYSLTR1, PTGIR 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
747 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
DRD1 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 |
D09886 D09886 💬 |
Dexpramipexole | 002 [1] 2 💬 |
748 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
DRD1 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 |
D00059 D00059 💬 |
Levodopa | 002 [8] 2 , 4 , 6 , 17, 90, 140, 164, 201 💬 |
749 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
DRD2 [1] DRD2 💬 |
D09953 D09953 💬 |
Pridopidine | 002 [3] 2 , 6 , 8 💬 |
750 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
DRD2 [1] DRD2 💬 |
D01226 D01226 💬 |
Sulpiride | 002 [5] 2 , 6 , 17, 46, 70 💬 |
751 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
DRD2 [1] DRD2 💬 |
D08549 D08549 💬 |
Sulpiride | 002 [5] 2 , 6 , 17, 46, 70 💬 |
752 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
DRD2 [2] DRD2, DRD3 💬 |
D00560 D00560 💬 |
Pimozide | 002 [1] 2 💬 |
753 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
DRD2 [3] DRD2, DRD3, DRD4 💬 |
D00559 D00559 💬 |
Pramipexole | 002 [2] 2 , 6 💬 |
754 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
DRD2 [3] DRD2, DRD3, DRD4 💬 |
D05575 D05575 💬 |
Pramipexole | 002 [2] 2 , 6 💬 |
755 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
DRD2 [3] DRD2, DRD3, DRD4 💬 |
D00784 D00784 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
756 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
DRD2 [3] DRD2, DRD3, DRD4 💬 |
D08489 D08489 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
757 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GABBR1 [2] GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 [5] 2 , 10, 13, 18, 149 💬 |
758 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
759 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00696 D00696 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
760 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D05028 D05028 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
761 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [20] 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
762 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GNRHR [1] GNRHR 💬 |
D00989 D00989 💬 |
Leuprolide | 001 [5] 1 , 2 , 3 , 51, 76 💬 |
763 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
764 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D02696 D02696 💬 |
Talampanel | 002 [2] 2 , 6 💬 |
765 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GRIA1 [14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 [8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬 |
766 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
767 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
768 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
769 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
770 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
771 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
772 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
773 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
774 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
HRH2 [1] HRH2 💬 |
D00295 D00295 💬 |
Cimetidine | 002 [1] 2 💬 |
775 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
HRH2 [1] HRH2 💬 |
D03503 D03503 💬 |
Cimetidine | 002 [1] 2 💬 |
776 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
HTR2A [3] HTR2A, HTR2B, HTR2C 💬 |
D00820 D00820 💬 |
Trazodone | 002 [1] 2 💬 |
777 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
HTR2A [3] HTR2A, HTR2B, HTR2C 💬 |
D08626 D08626 💬 |
Trazodone | 002 [1] 2 💬 |
778 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
MC2R [1] MC2R 💬 |
D00146 D00146 💬 |
Corticotropin | 002 [13] 2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬 |
779 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00244 D00244 💬 |
Betamethasone | 002 [6] 2 , 28, 46, 90, 96, 235 💬 |
780 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00972 D00972 💬 |
Betamethasone | 002 [6] 2 , 28, 46, 90, 96, 235 💬 |
781 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D01357 D01357 💬 |
Betamethasone | 002 [6] 2 , 28, 46, 90, 96, 235 💬 |
782 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D01402 D01402 💬 |
Betamethasone | 002 [6] 2 , 28, 46, 90, 96, 235 💬 |
783 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D01637 D01637 💬 |
Betamethasone | 002 [6] 2 , 28, 46, 90, 96, 235 💬 |
784 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D02032 D02032 💬 |
Betamethasone | 002 [6] 2 , 28, 46, 90, 96, 235 💬 |
785 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D02286 D02286 💬 |
Betamethasone | 002 [6] 2 , 28, 46, 90, 96, 235 💬 |
786 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00407 D00407 💬 |
Methylprednisolone | 002 [44] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
787 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00751 D00751 💬 |
Methylprednisolone | 002 [44] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
788 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00979 D00979 💬 |
Methylprednisolone | 002 [44] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
789 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D05000 D05000 💬 |
Methylprednisolone | 002 [44] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
790 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D05001 D05001 💬 |
Methylprednisolone | 002 [44] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
791 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D05002 D05002 💬 |
Methylprednisolone | 002 [44] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
792 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00473 D00473 💬 |
Prednisone | 002 [47] 2 , 6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 93, 95, 96, 97, 113, 127, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬 |
793 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
TRPV1 [1] TRPV1 💬 |
D00250 D00250 💬 |
Capsaicin | 002 [5] 2 , 6 , 19, 86, 226 💬 |
794 | Neurotrophin signaling pathway 💬 19 genes, 21 drugs (DrugBank) and 29 diseases |
ABL1 [1] ABL1 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
795 | Neurotrophin signaling pathway 💬 19 genes, 21 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
796 | Neutrophil extracellular trap formation 💬 32 genes, 27 drugs (DrugBank) and 56 diseases |
C5 [1] C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 [5] 2 , 11, 13, 62, 109 💬 |
797 | Neutrophil extracellular trap formation 💬 32 genes, 27 drugs (DrugBank) and 56 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
798 | Neutrophil extracellular trap formation 💬 32 genes, 27 drugs (DrugBank) and 56 diseases |
MPO [1] MPO 💬 |
D11684 D11684 💬 |
Verdiperstat | 002 [2] 2 , 17 💬 |
799 | Neutrophil extracellular trap formation 💬 32 genes, 27 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
800 | Neutrophil extracellular trap formation 💬 32 genes, 27 drugs (DrugBank) and 56 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
801 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
802 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
803 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
804 | Nicotine addiction 💬 30 genes, 32 drugs (DrugBank) and 40 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
805 | Nicotine addiction 💬 30 genes, 32 drugs (DrugBank) and 40 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00696 D00696 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
806 | Nicotine addiction 💬 30 genes, 32 drugs (DrugBank) and 40 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D05028 D05028 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
807 | Nicotine addiction 💬 30 genes, 32 drugs (DrugBank) and 40 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
808 | Nicotine addiction 💬 30 genes, 32 drugs (DrugBank) and 40 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D02696 D02696 💬 |
Talampanel | 002 [2] 2 , 6 💬 |
809 | Nicotine addiction 💬 30 genes, 32 drugs (DrugBank) and 40 diseases |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 [8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬 |
810 | Nicotine addiction 💬 30 genes, 32 drugs (DrugBank) and 40 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
811 | Nicotine addiction 💬 30 genes, 32 drugs (DrugBank) and 40 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
812 | Nicotine addiction 💬 30 genes, 32 drugs (DrugBank) and 40 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
813 | Nicotine addiction 💬 30 genes, 32 drugs (DrugBank) and 40 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
814 | Nicotine addiction 💬 30 genes, 32 drugs (DrugBank) and 40 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
815 | Nicotine addiction 💬 30 genes, 32 drugs (DrugBank) and 40 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
816 | Nicotine addiction 💬 30 genes, 32 drugs (DrugBank) and 40 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
817 | Nicotine addiction 💬 30 genes, 32 drugs (DrugBank) and 40 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
818 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
819 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
820 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
821 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
822 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
823 | Non-small cell lung cancer 💬 18 genes, 27 drugs (DrugBank) and 42 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
824 | Non-small cell lung cancer 💬 18 genes, 27 drugs (DrugBank) and 42 diseases |
RARB [1] RARB 💬 |
D00094 D00094 💬 |
Tretinoin | 002 [5] 2 , 63, 75, 94, 231 💬 |
825 | Olfactory transduction 💬 4 genes, 3 drugs (DrugBank) and 12 diseases |
PDE1B [2] PDE1B, PDE2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
826 | Olfactory transduction 💬 4 genes, 3 drugs (DrugBank) and 12 diseases |
PDE1B [2] PDE1B, PDE2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
827 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
AR [1] AR 💬 |
D00075 D00075 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
828 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
AR [1] AR 💬 |
D00957 D00957 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
829 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
AR [1] AR 💬 |
D00958 D00958 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
830 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
AR [1] AR 💬 |
D00959 D00959 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
831 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
AR [1] AR 💬 |
D06085 D06085 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
832 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
AR [1] AR 💬 |
D06087 D06087 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
833 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
MAP2K1 [1] MAP2K1 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
834 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
835 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
836 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
837 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
MAP2K1 [1] MAP2K1 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
838 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
839 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
840 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
841 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
842 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
843 | Ovarian steroidogenesis 💬 6 genes, 34 drugs (DrugBank) and 47 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
844 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 23 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D00724 D00724 💬 |
Rabeprazole | 002 [2] 2 , 51 💬 |
845 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 23 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D08463 D08463 💬 |
Rabeprazole | 002 [2] 2 , 51 💬 |
846 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
847 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
848 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
849 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
850 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
851 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
852 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [2] 2 , 51 💬 |
853 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
854 | Pancreatic cancer 💬 16 genes, 29 drugs (DrugBank) and 64 diseases |
MAP2K1 [1] MAP2K1 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
855 | Pancreatic cancer 💬 16 genes, 29 drugs (DrugBank) and 64 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
856 | Pancreatic secretion 💬 10 genes, 34 drugs (DrugBank) and 33 diseases |
CHRM3 [1] CHRM3 💬 |
D00113 D00113 💬 |
Atropine | 002 [1] 2 💬 |
857 | Pancreatic secretion 💬 10 genes, 34 drugs (DrugBank) and 33 diseases |
CHRM3 [1] CHRM3 💬 |
D01077 D01077 💬 |
Atropine | 002 [1] 2 💬 |
858 | Pancreatic secretion 💬 10 genes, 34 drugs (DrugBank) and 33 diseases |
CHRM3 [1] CHRM3 💬 |
D02069 D02069 💬 |
Atropine | 002 [1] 2 💬 |
859 | Pancreatic secretion 💬 10 genes, 34 drugs (DrugBank) and 33 diseases |
CHRM3 [1] CHRM3 💬 |
D03011 D03011 💬 |
Atropine | 002 [1] 2 💬 |
860 | Pancreatic secretion 💬 10 genes, 34 drugs (DrugBank) and 33 diseases |
CHRM3 [1] CHRM3 💬 |
D03814 D03814 💬 |
Atropine | 002 [1] 2 💬 |
861 | Pancreatic secretion 💬 10 genes, 34 drugs (DrugBank) and 33 diseases |
CHRM3 [1] CHRM3 💬 |
D00138 D00138 💬 |
Scopolamine | 002 [1] 2 💬 |
862 | Pancreatic secretion 💬 10 genes, 34 drugs (DrugBank) and 33 diseases |
KCNQ1 [1] KCNQ1 💬 |
D09569 D09569 💬 |
Ezogabine | 002 [2] 2 , 144 💬 |
863 | Parathyroid hormone synthesis, secretion and action 💬 19 genes, 40 drugs (DrugBank) and 58 diseases |
MAP2K1 [1] MAP2K1 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
864 | Parathyroid hormone synthesis, secretion and action 💬 19 genes, 40 drugs (DrugBank) and 58 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
865 | Parathyroid hormone synthesis, secretion and action 💬 19 genes, 40 drugs (DrugBank) and 58 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
866 | Parathyroid hormone synthesis, secretion and action 💬 19 genes, 40 drugs (DrugBank) and 58 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
867 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
ADORA2A [1] ADORA2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
868 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
ADORA2A [1] ADORA2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
869 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
DRD1 [2] DRD1, DRD2 💬 |
D09886 D09886 💬 |
Dexpramipexole | 002 [1] 2 💬 |
870 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
DRD1 [2] DRD1, DRD2 💬 |
D00059 D00059 💬 |
Levodopa | 002 [8] 2 , 4 , 6 , 17, 90, 140, 164, 201 💬 |
871 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
DRD2 [1] DRD2 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
872 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
DRD2 [1] DRD2 💬 |
D06623 D06623 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
873 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
DRD2 [1] DRD2 💬 |
D00560 D00560 💬 |
Pimozide | 002 [1] 2 💬 |
874 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
DRD2 [1] DRD2 💬 |
D00559 D00559 💬 |
Pramipexole | 002 [2] 2 , 6 💬 |
875 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
DRD2 [1] DRD2 💬 |
D05575 D05575 💬 |
Pramipexole | 002 [2] 2 , 6 💬 |
876 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
DRD2 [1] DRD2 💬 |
D09953 D09953 💬 |
Pridopidine | 002 [3] 2 , 6 , 8 💬 |
877 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
DRD2 [1] DRD2 💬 |
D00784 D00784 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
878 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
DRD2 [1] DRD2 💬 |
D08489 D08489 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
879 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
DRD2 [1] DRD2 💬 |
D01226 D01226 💬 |
Sulpiride | 002 [5] 2 , 6 , 17, 46, 70 💬 |
880 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
DRD2 [1] DRD2 💬 |
D08549 D08549 💬 |
Sulpiride | 002 [5] 2 , 6 , 17, 46, 70 💬 |
881 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
882 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
883 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
884 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D00570 D00570 💬 |
Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬 |
885 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
ABL1 [2] ABL1, SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
886 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
887 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [2] 2 , 51 💬 |
888 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
889 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D00570 D00570 💬 |
Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬 |
890 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
ABL1 [1] ABL1 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
891 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
AR [1] AR 💬 |
D00075 D00075 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
892 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
AR [1] AR 💬 |
D00957 D00957 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
893 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
AR [1] AR 💬 |
D00958 D00958 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
894 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
AR [1] AR 💬 |
D00959 D00959 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
895 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
AR [1] AR 💬 |
D06085 D06085 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
896 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
AR [1] AR 💬 |
D06087 D06087 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
897 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
CSF3R [1] CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 [33] 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
898 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
CSF3R [1] CSF3R 💬 |
D03247 D03247 💬 |
Lenograstim | 002 [7] 2 , 13, 16, 18, 19, 57, 65 💬 |
899 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
EPOR [1] EPOR 💬 |
D03231 D03231 💬 |
Erythropoietin | 002 [10] 2 , 6 , 13, 18, 22, 46, 47, 70, 95, 96 💬 |
900 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D00966 D00966 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
901 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
902 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [7] 2 , 50, 65, 66, 97, 222, 228 💬 |
903 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
904 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
905 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
906 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
907 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
908 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
PML [3] PML, RARA, RARB 💬 |
D00094 D00094 💬 |
Tretinoin | 002 [5] 2 , 63, 75, 94, 231 💬 |
909 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
910 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
911 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
912 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [2] 2 , 51 💬 |
913 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D00113 D00113 💬 |
Atropine | 002 [1] 2 💬 |
914 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D01077 D01077 💬 |
Atropine | 002 [1] 2 💬 |
915 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D02069 D02069 💬 |
Atropine | 002 [1] 2 💬 |
916 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D03011 D03011 💬 |
Atropine | 002 [1] 2 💬 |
917 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D03814 D03814 💬 |
Atropine | 002 [1] 2 💬 |
918 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D00138 D00138 💬 |
Scopolamine | 002 [1] 2 💬 |
919 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
920 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D02696 D02696 💬 |
Talampanel | 002 [2] 2 , 6 💬 |
921 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 [8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬 |
922 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
923 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
924 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
925 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
926 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
927 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
GRIN1 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
928 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
GRIN1 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
929 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
GRIN1 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
930 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
931 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
932 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
933 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
934 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
935 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
936 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D00570 D00570 💬 |
Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬 |
937 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
938 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
939 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
940 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
941 | Peroxisome 💬 2 genes, 3 drugs (DrugBank) and 9 diseases |
XDH [1] XDH 💬 |
D01206 D01206 💬 |
Febuxostat | 002 [3] 2 , 6 , 13 💬 |
942 | Pertussis 💬 16 genes, 32 drugs (DrugBank) and 65 diseases |
C5 [1] C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 [5] 2 , 11, 13, 62, 109 💬 |
943 | Pertussis 💬 16 genes, 32 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
944 | Phagosome 💬 31 genes, 8 drugs (DrugBank) and 18 diseases |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
945 | Phagosome 💬 31 genes, 8 drugs (DrugBank) and 18 diseases |
MPO [1] MPO 💬 |
D11684 D11684 💬 |
Verdiperstat | 002 [2] 2 , 17 💬 |
946 | Phagosome 💬 31 genes, 8 drugs (DrugBank) and 18 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D00570 D00570 💬 |
Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬 |
947 | Phenylalanine metabolism 💬 6 genes, 11 drugs (DrugBank) and 14 diseases |
DDC [1] DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 002 [9] 2 , 4 , 6 , 13, 17, 90, 140, 164, 201 💬 |
948 | Phenylalanine metabolism 💬 6 genes, 11 drugs (DrugBank) and 14 diseases |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
949 | Phenylalanine metabolism 💬 6 genes, 11 drugs (DrugBank) and 14 diseases |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
950 | Phenylalanine metabolism 💬 6 genes, 11 drugs (DrugBank) and 14 diseases |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
951 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
952 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
953 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
954 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
D00113 D00113 💬 |
Atropine | 002 [1] 2 💬 |
955 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
D01077 D01077 💬 |
Atropine | 002 [1] 2 💬 |
956 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
D02069 D02069 💬 |
Atropine | 002 [1] 2 💬 |
957 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
D03011 D03011 💬 |
Atropine | 002 [1] 2 💬 |
958 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
D03814 D03814 💬 |
Atropine | 002 [1] 2 💬 |
959 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
D00138 D00138 💬 |
Scopolamine | 002 [1] 2 💬 |
960 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
CSF3R [1] CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 [33] 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
961 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
CSF3R [1] CSF3R 💬 |
D03247 D03247 💬 |
Lenograstim | 002 [7] 2 , 13, 16, 18, 19, 57, 65 💬 |
962 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
EPOR [1] EPOR 💬 |
D03231 D03231 💬 |
Erythropoietin | 002 [10] 2 , 6 , 13, 18, 22, 46, 47, 70, 95, 96 💬 |
963 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [20] 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
964 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [7] 2 , 50, 65, 66, 97, 222, 228 💬 |
965 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
966 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
967 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
968 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
969 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
970 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
971 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
972 | Platelet activation 💬 22 genes, 44 drugs (DrugBank) and 47 diseases |
PTGIR [1] PTGIR 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
973 | Platelet activation 💬 22 genes, 44 drugs (DrugBank) and 47 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [2] 2 , 51 💬 |
974 | Platelet activation 💬 22 genes, 44 drugs (DrugBank) and 47 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
975 | PPAR signaling pathway 💬 10 genes, 12 drugs (DrugBank) and 30 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
976 | PPAR signaling pathway 💬 10 genes, 12 drugs (DrugBank) and 30 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
977 | Primary immunodeficiency 💬 10 genes, 17 drugs (DrugBank) and 22 diseases |
IL2RG [1] IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
978 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
C5 [1] C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 [5] 2 , 11, 13, 62, 109 💬 |
979 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
980 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
981 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
982 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
983 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
984 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
985 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
986 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
987 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 [8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬 |
988 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
989 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
990 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
991 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D00570 D00570 💬 |
Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬 |
992 | Progesterone-mediated oocyte maturation 💬 14 genes, 32 drugs (DrugBank) and 37 diseases |
MAP2K1 [1] MAP2K1 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
993 | Progesterone-mediated oocyte maturation 💬 14 genes, 32 drugs (DrugBank) and 37 diseases |
PDE3B [1] PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
994 | Progesterone-mediated oocyte maturation 💬 14 genes, 32 drugs (DrugBank) and 37 diseases |
PDE3B [1] PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
995 | Progesterone-mediated oocyte maturation 💬 14 genes, 32 drugs (DrugBank) and 37 diseases |
PDE3B [1] PDE3B 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
996 | Progesterone-mediated oocyte maturation 💬 14 genes, 32 drugs (DrugBank) and 37 diseases |
PDE3B [1] PDE3B 💬 |
D04720 D04720 💬 |
Levosimendan | 002 [1] 2 💬 |
997 | Prolactin signaling pathway 💬 18 genes, 33 drugs (DrugBank) and 48 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D00966 D00966 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
998 | Prolactin signaling pathway 💬 18 genes, 33 drugs (DrugBank) and 48 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
999 | Prolactin signaling pathway 💬 18 genes, 33 drugs (DrugBank) and 48 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
1000 | Prolactin signaling pathway 💬 18 genes, 33 drugs (DrugBank) and 48 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
1001 | Propanoate metabolism 💬 1 gene, 2 drugs (DrugBank) and 18 diseases |
ABAT [1] ABAT 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [16] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬 |
1002 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
AR [1] AR 💬 |
D00075 D00075 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
1003 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
AR [1] AR 💬 |
D00957 D00957 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
1004 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
AR [1] AR 💬 |
D00958 D00958 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
1005 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
AR [1] AR 💬 |
D00959 D00959 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
1006 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
AR [1] AR 💬 |
D06085 D06085 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
1007 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
AR [1] AR 💬 |
D06087 D06087 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
1008 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
IL1R2 [1] IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
1009 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
1010 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1011 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
SRD5A2 [1] SRD5A2 💬 |
D03820 D03820 💬 |
Dutasteride | 001 [2] 1 , 2 💬 |
1012 | Protein digestion and absorption 💬 7 genes, 7 drugs (DrugBank) and 12 diseases |
KCNQ1 [1] KCNQ1 💬 |
D09569 D09569 💬 |
Ezogabine | 002 [2] 2 , 144 💬 |
1013 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
ESR1 [1] ESR1 💬 |
D00966 D00966 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
1014 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
ESR1 [1] ESR1 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
1015 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
1016 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1017 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [2] 2 , 51 💬 |
1018 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
1019 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1020 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D00752 D00752 💬 |
Mycophenolate mofetil | 002 [32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
1021 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05094 D05094 💬 |
Mycophenolate mofetil | 002 [32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
1022 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05095 D05095 💬 |
Mycophenolate mofetil | 002 [32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
1023 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05096 D05096 💬 |
Mycophenolic acid | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 |
1024 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
PDE1B [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1025 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
PDE1B [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1026 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
D04720 D04720 💬 |
Levosimendan | 002 [1] 2 💬 |
1027 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
PDE3A [6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
1028 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
XDH [1] XDH 💬 |
D01206 D01206 💬 |
Febuxostat | 002 [3] 2 , 6 , 13 💬 |
1029 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
ADORA2A [1] ADORA2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1030 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
ADORA2A [1] ADORA2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1031 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
CNR1 [1] CNR1 💬 |
D10915 D10915 💬 |
Cannabidiol | 002 [19] 2 , 6 , 8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 |
1032 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
CNR1 [1] CNR1 💬 |
D00306 D00306 💬 |
Dronabinol | 002 [7] 2 , 8 , 13, 46, 96, 271, 298 💬 |
1033 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
DRD2 [1] DRD2 💬 |
D09886 D09886 💬 |
Dexpramipexole | 002 [1] 2 💬 |
1034 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
DRD2 [1] DRD2 💬 |
D00059 D00059 💬 |
Levodopa | 002 [8] 2 , 4 , 6 , 17, 90, 140, 164, 201 💬 |
1035 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
DRD2 [1] DRD2 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
1036 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
DRD2 [1] DRD2 💬 |
D06623 D06623 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
1037 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
DRD2 [1] DRD2 💬 |
D00560 D00560 💬 |
Pimozide | 002 [1] 2 💬 |
1038 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
DRD2 [1] DRD2 💬 |
D00559 D00559 💬 |
Pramipexole | 002 [2] 2 , 6 💬 |
1039 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
DRD2 [1] DRD2 💬 |
D05575 D05575 💬 |
Pramipexole | 002 [2] 2 , 6 💬 |
1040 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
DRD2 [1] DRD2 💬 |
D09953 D09953 💬 |
Pridopidine | 002 [3] 2 , 6 , 8 💬 |
1041 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
DRD2 [1] DRD2 💬 |
D00784 D00784 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
1042 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
DRD2 [1] DRD2 💬 |
D08489 D08489 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
1043 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
DRD2 [1] DRD2 💬 |
D01226 D01226 💬 |
Sulpiride | 002 [5] 2 , 6 , 17, 46, 70 💬 |
1044 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
DRD2 [1] DRD2 💬 |
D08549 D08549 💬 |
Sulpiride | 002 [5] 2 , 6 , 17, 46, 70 💬 |
1045 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1046 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1047 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1048 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
1049 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
1050 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
1051 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
1052 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
1053 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D00775 D00775 💬 |
Riluzole | 002 [8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬 |
1054 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
1055 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
1056 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
1057 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
ABL1 [1] ABL1 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
1058 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1059 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1060 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1061 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
1062 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
1063 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
1064 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
1065 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
1066 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D00775 D00775 💬 |
Riluzole | 002 [8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬 |
1067 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
1068 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
1069 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00113 D00113 💬 |
Atropine | 002 [1] 2 💬 |
1070 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D01077 D01077 💬 |
Atropine | 002 [1] 2 💬 |
1071 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D02069 D02069 💬 |
Atropine | 002 [1] 2 💬 |
1072 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D03011 D03011 💬 |
Atropine | 002 [1] 2 💬 |
1073 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D03814 D03814 💬 |
Atropine | 002 [1] 2 💬 |
1074 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00138 D00138 💬 |
Scopolamine | 002 [1] 2 💬 |
1075 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
1076 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [2] 2 , 51 💬 |
1077 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
1078 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
ADORA1 [2] ADORA1, PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1079 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
ADORA1 [2] ADORA1, PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1080 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
ADRB2 [1] ADRB2 💬 |
D07713 D07713 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 |
1081 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
PDE3B [1] PDE3B 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
1082 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
PDE3B [1] PDE3B 💬 |
D04720 D04720 💬 |
Levosimendan | 002 [1] 2 💬 |
1083 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
1084 | Relaxin signaling pathway 💬 18 genes, 25 drugs (DrugBank) and 38 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
1085 | Relaxin signaling pathway 💬 18 genes, 25 drugs (DrugBank) and 38 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
1086 | Renal cell carcinoma 💬 12 genes, 12 drugs (DrugBank) and 21 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
1087 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ADORA1 [4] ADORA1, PDE1B, PDE3A, PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1088 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ADORA1 [4] ADORA1, PDE1B, PDE3A, PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1089 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ADRB2 [1] ADRB2 💬 |
D07713 D07713 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 |
1090 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
1091 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
D04720 D04720 💬 |
Levosimendan | 002 [1] 2 💬 |
1092 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1093 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1094 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
CNR1 [1] CNR1 💬 |
D10915 D10915 💬 |
Cannabidiol | 002 [19] 2 , 6 , 8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 |
1095 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
CNR1 [1] CNR1 💬 |
D00306 D00306 💬 |
Dronabinol | 002 [7] 2 , 8 , 13, 46, 96, 271, 298 💬 |
1096 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
1097 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00696 D00696 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
1098 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D05028 D05028 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
1099 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
1100 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D00775 D00775 💬 |
Riluzole | 002 [8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬 |
1101 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D02696 D02696 💬 |
Talampanel | 002 [2] 2 , 6 💬 |
1102 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
1103 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
1104 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1105 | RIG-I-like receptor signaling pathway 💬 21 genes, 17 drugs (DrugBank) and 53 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1106 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
1107 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D06623 D06623 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
1108 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
ADRB2 [1] ADRB2 💬 |
D07713 D07713 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 |
1109 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
CHRM3 [1] CHRM3 💬 |
D00113 D00113 💬 |
Atropine | 002 [1] 2 💬 |
1110 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
CHRM3 [1] CHRM3 💬 |
D01077 D01077 💬 |
Atropine | 002 [1] 2 💬 |
1111 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
CHRM3 [1] CHRM3 💬 |
D02069 D02069 💬 |
Atropine | 002 [1] 2 💬 |
1112 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
CHRM3 [1] CHRM3 💬 |
D03011 D03011 💬 |
Atropine | 002 [1] 2 💬 |
1113 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
CHRM3 [1] CHRM3 💬 |
D03814 D03814 💬 |
Atropine | 002 [1] 2 💬 |
1114 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
CHRM3 [1] CHRM3 💬 |
D00138 D00138 💬 |
Scopolamine | 002 [1] 2 💬 |
1115 | Salmonella infection 💬 25 genes, 32 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
1116 | Salmonella infection 💬 25 genes, 32 drugs (DrugBank) and 62 diseases |
ROCK2 [1] ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [2] 2 , 51 💬 |
1117 | Salmonella infection 💬 25 genes, 32 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1118 | Salmonella infection 💬 25 genes, 32 drugs (DrugBank) and 62 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D00570 D00570 💬 |
Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬 |
1119 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
DDC [1] DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 002 [9] 2 , 4 , 6 , 13, 17, 90, 140, 164, 201 💬 |
1120 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬 |
D00550 D00550 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
1121 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬 |
D00696 D00696 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
1122 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬 |
D05028 D05028 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
1123 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
HTR2A [4] HTR2A, HTR2B, HTR2C, HTR6 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
1124 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
HTR2A [4] HTR2A, HTR2B, HTR2C, HTR6 💬 |
D06623 D06623 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
1125 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
HTR2A [4] HTR2A, HTR2B, HTR2C, SLC6A4 💬 |
D00820 D00820 💬 |
Trazodone | 002 [1] 2 💬 |
1126 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
HTR2A [4] HTR2A, HTR2B, HTR2C, SLC6A4 💬 |
D08626 D08626 💬 |
Trazodone | 002 [1] 2 💬 |
1127 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
1128 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
1129 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
1130 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
MAP2K1 [1] MAP2K1 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
1131 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
1132 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
SLC6A4 [1] SLC6A4 💬 |
D02567 D02567 💬 |
Escitalopram | 002 [3] 2 , 6 , 13 💬 |
1133 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
SLC6A4 [1] SLC6A4 💬 |
D07704 D07704 💬 |
Escitalopram | 002 [3] 2 , 6 , 13 💬 |
1134 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
SLC6A4 [1] SLC6A4 💬 |
D07913 D07913 💬 |
Escitalopram | 002 [3] 2 , 6 , 13 💬 |
1135 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
1136 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1137 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [2] 2 , 51 💬 |
1138 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
1139 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1140 | Signaling pathways regulating pluripotency of stem cells 💬 20 genes, 24 drugs (DrugBank) and 43 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
1141 | Small cell lung cancer 💬 11 genes, 35 drugs (DrugBank) and 51 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
1142 | Small cell lung cancer 💬 11 genes, 35 drugs (DrugBank) and 51 diseases |
RARB [1] RARB 💬 |
D00094 D00094 💬 |
Tretinoin | 002 [5] 2 , 63, 75, 94, 231 💬 |
1143 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
ADORA1 [1] ADORA1 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1144 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
ADORA1 [1] ADORA1 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1145 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
1146 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [2] 2 , 51 💬 |
1147 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1148 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
GRIA1 [3] GRIA1, GRIA2, GRIA3 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
1149 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
GRIA1 [3] GRIA1, GRIA2, GRIA3 💬 |
D02696 D02696 💬 |
Talampanel | 002 [2] 2 , 6 💬 |
1150 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
GRIA1 [8] GRIA1, GRIA2, GRIA3, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 [8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬 |
1151 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1152 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1153 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1154 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
1155 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
1156 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
1157 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
1158 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
1159 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1160 | Staphylococcus aureus infection 💬 24 genes, 15 drugs (DrugBank) and 32 diseases |
C5 [1] C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 [5] 2 , 11, 13, 62, 109 💬 |
1161 | Staphylococcus aureus infection 💬 24 genes, 15 drugs (DrugBank) and 32 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
1162 | Steroid hormone biosynthesis 💬 7 genes, 10 drugs (DrugBank) and 14 diseases |
SRD5A1 [2] SRD5A1, SRD5A2 💬 |
D03820 D03820 💬 |
Dutasteride | 001 [2] 1 , 2 💬 |
1163 | Synaptic vesicle cycle 💬 7 genes, 29 drugs (DrugBank) and 37 diseases |
SLC6A4 [1] SLC6A4 💬 |
D02567 D02567 💬 |
Escitalopram | 002 [3] 2 , 6 , 13 💬 |
1164 | Synaptic vesicle cycle 💬 7 genes, 29 drugs (DrugBank) and 37 diseases |
SLC6A4 [1] SLC6A4 💬 |
D07704 D07704 💬 |
Escitalopram | 002 [3] 2 , 6 , 13 💬 |
1165 | Synaptic vesicle cycle 💬 7 genes, 29 drugs (DrugBank) and 37 diseases |
SLC6A4 [1] SLC6A4 💬 |
D07913 D07913 💬 |
Escitalopram | 002 [3] 2 , 6 , 13 💬 |
1166 | Synaptic vesicle cycle 💬 7 genes, 29 drugs (DrugBank) and 37 diseases |
SLC6A4 [1] SLC6A4 💬 |
D00820 D00820 💬 |
Trazodone | 002 [1] 2 💬 |
1167 | Synaptic vesicle cycle 💬 7 genes, 29 drugs (DrugBank) and 37 diseases |
SLC6A4 [1] SLC6A4 💬 |
D08626 D08626 💬 |
Trazodone | 002 [1] 2 💬 |
1168 | Synaptic vesicle cycle 💬 7 genes, 29 drugs (DrugBank) and 37 diseases |
SNAP25 [1] SNAP25 💬 |
D02735 D02735 💬 |
Botulinum Toxin Type B | 002 [3] 2 , 6 , 51 💬 |
1169 | Synaptic vesicle cycle 💬 7 genes, 29 drugs (DrugBank) and 37 diseases |
SNAP25 [1] SNAP25 💬 |
D00783 D00783 💬 |
Botulinum toxin type A | 002 [13] 2 , 5 , 6 , 7 , 13, 15, 17, 36, 51, 70, 113, 149, 226 💬 |
1170 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
C5 [1] C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 [5] 2 , 11, 13, 62, 109 💬 |
1171 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1172 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1173 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1174 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
1175 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
1176 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
1177 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
1178 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
1179 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬 |
D00775 D00775 💬 |
Riluzole | 002 [8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬 |
1180 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
1181 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1182 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
1183 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1184 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1185 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1186 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
CHRM3 [1] CHRM3 💬 |
D00113 D00113 💬 |
Atropine | 002 [1] 2 💬 |
1187 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
CHRM3 [1] CHRM3 💬 |
D01077 D01077 💬 |
Atropine | 002 [1] 2 💬 |
1188 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
CHRM3 [1] CHRM3 💬 |
D02069 D02069 💬 |
Atropine | 002 [1] 2 💬 |
1189 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
CHRM3 [1] CHRM3 💬 |
D03011 D03011 💬 |
Atropine | 002 [1] 2 💬 |
1190 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
CHRM3 [1] CHRM3 💬 |
D03814 D03814 💬 |
Atropine | 002 [1] 2 💬 |
1191 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
CHRM3 [1] CHRM3 💬 |
D00138 D00138 💬 |
Scopolamine | 002 [1] 2 💬 |
1192 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
GABBR1 [2] GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 [5] 2 , 10, 13, 18, 149 💬 |
1193 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00550 D00550 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
1194 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00696 D00696 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
1195 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D05028 D05028 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
1196 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
PDE1B [1] PDE1B 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1197 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
PDE1B [1] PDE1B 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1198 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D00639 D00639 💬 |
Mexiletine | 001 [5] 1 , 2 , 10, 113, 114 💬 |
1199 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D08215 D08215 💬 |
Mexiletine | 001 [5] 1 , 2 , 10, 113, 114 💬 |
1200 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D00642 D00642 💬 |
Quinidine | 002 [3] 2 , 8 , 13 💬 |
1201 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D00643 D00643 💬 |
Quinidine | 002 [3] 2 , 8 , 13 💬 |
1202 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D02272 D02272 💬 |
Quinidine | 002 [3] 2 , 8 , 13 💬 |
1203 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D08458 D08458 💬 |
Quinidine | 002 [3] 2 , 8 , 13 💬 |
1204 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
SCN3A [2] SCN3A, SCN9A 💬 |
D07299 D07299 💬 |
Lacosamide | 002 [3] 2 , 46, 149 💬 |
1205 | Taurine and hypotaurine metabolism 💬 2 genes, 1 drug (DrugBank) and 16 diseases |
GAD1 [2] GAD1, GAD2 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [16] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬 |
1206 | TGF-beta signaling pathway 💬 11 genes, 20 drugs (DrugBank) and 54 diseases |
ROCK1 [1] ROCK1 💬 |
D07941 D07941 💬 |
Fasudil | 002 [2] 2 , 51 💬 |
1207 | TGF-beta signaling pathway 💬 11 genes, 20 drugs (DrugBank) and 54 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1208 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
1209 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [7] 2 , 50, 65, 66, 97, 222, 228 💬 |
1210 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
1211 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1212 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1213 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
1214 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
1215 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [7] 2 , 50, 65, 66, 97, 222, 228 💬 |
1216 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
1217 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
1218 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1219 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1220 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1221 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
RARA [1] RARA 💬 |
D00094 D00094 💬 |
Tretinoin | 002 [5] 2 , 63, 75, 94, 231 💬 |
1222 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
CNR1 [1] CNR1 💬 |
D10915 D10915 💬 |
Cannabidiol | 002 [19] 2 , 6 , 8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 |
1223 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
CNR1 [1] CNR1 💬 |
D00306 D00306 💬 |
Dronabinol | 002 [7] 2 , 8 , 13, 46, 96, 271, 298 💬 |
1224 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1225 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
1226 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
1227 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
1228 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
1229 | Thyroid cancer 💬 8 genes, 12 drugs (DrugBank) and 25 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
1230 | Thyroid cancer 💬 8 genes, 12 drugs (DrugBank) and 25 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
1231 | Thyroid cancer 💬 8 genes, 12 drugs (DrugBank) and 25 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
1232 | Thyroid hormone signaling pathway 💬 22 genes, 35 drugs (DrugBank) and 61 diseases |
ESR1 [1] ESR1 💬 |
D00966 D00966 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
1233 | Thyroid hormone signaling pathway 💬 22 genes, 35 drugs (DrugBank) and 61 diseases |
ESR1 [1] ESR1 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
1234 | Thyroid hormone signaling pathway 💬 22 genes, 35 drugs (DrugBank) and 61 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
1235 | Thyroid hormone signaling pathway 💬 22 genes, 35 drugs (DrugBank) and 61 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1236 | Thyroid hormone signaling pathway 💬 22 genes, 35 drugs (DrugBank) and 61 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
1237 | Tight junction 💬 10 genes, 26 drugs (DrugBank) and 40 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
1238 | Tight junction 💬 10 genes, 26 drugs (DrugBank) and 40 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
1239 | Tight junction 💬 10 genes, 26 drugs (DrugBank) and 40 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [2] 2 , 51 💬 |
1240 | Tight junction 💬 10 genes, 26 drugs (DrugBank) and 40 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
1241 | TNF signaling pathway 💬 18 genes, 51 drugs (DrugBank) and 79 diseases |
MAP2K1 [1] MAP2K1 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
1242 | TNF signaling pathway 💬 18 genes, 51 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
1243 | TNF signaling pathway 💬 18 genes, 51 drugs (DrugBank) and 79 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1244 | Toll-like receptor signaling pathway 💬 34 genes, 39 drugs (DrugBank) and 64 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
1245 | Toll-like receptor signaling pathway 💬 34 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1246 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
1247 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1248 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
GRIA3 [1] GRIA3 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
1249 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
GRIA3 [1] GRIA3 💬 |
D00775 D00775 💬 |
Riluzole | 002 [8] 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬 |
1250 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
GRIA3 [1] GRIA3 💬 |
D02696 D02696 💬 |
Talampanel | 002 [2] 2 , 6 💬 |
1251 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
IL1R2 [1] IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
1252 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
IL2RB [1] IL2RB 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
1253 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
MPO [1] MPO 💬 |
D11684 D11684 💬 |
Verdiperstat | 002 [2] 2 , 17 💬 |
1254 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
PML [2] PML, RARA 💬 |
D00094 D00094 💬 |
Tretinoin | 002 [5] 2 , 63, 75, 94, 231 💬 |
1255 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
1256 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
1257 | Tryptophan metabolism 💬 5 genes, 9 drugs (DrugBank) and 12 diseases |
DDC [1] DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 002 [9] 2 , 4 , 6 , 13, 17, 90, 140, 164, 201 💬 |
1258 | Tryptophan metabolism 💬 5 genes, 9 drugs (DrugBank) and 12 diseases |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
1259 | Tryptophan metabolism 💬 5 genes, 9 drugs (DrugBank) and 12 diseases |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
1260 | Tryptophan metabolism 💬 5 genes, 9 drugs (DrugBank) and 12 diseases |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
1261 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
1262 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1263 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1264 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
1265 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1266 | Type I diabetes mellitus 💬 31 genes, 23 drugs (DrugBank) and 69 diseases |
GAD1 [2] GAD1, GAD2 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [16] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬 |
1267 | Type I diabetes mellitus 💬 31 genes, 23 drugs (DrugBank) and 69 diseases |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
1268 | Type I diabetes mellitus 💬 31 genes, 23 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1269 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
CACNA1G [1] CACNA1G 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [16] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬 |
1270 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1271 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1272 | Tyrosine metabolism 💬 10 genes, 15 drugs (DrugBank) and 17 diseases |
DDC [1] DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 002 [9] 2 , 4 , 6 , 13, 17, 90, 140, 164, 201 💬 |
1273 | Tyrosine metabolism 💬 10 genes, 15 drugs (DrugBank) and 17 diseases |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
1274 | Tyrosine metabolism 💬 10 genes, 15 drugs (DrugBank) and 17 diseases |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
1275 | Tyrosine metabolism 💬 10 genes, 15 drugs (DrugBank) and 17 diseases |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 13, 17, 66 💬 |
1276 | Ubiquitin mediated proteolysis 💬 2 genes, 2 drugs (DrugBank) and 9 diseases |
PML [1] PML 💬 |
D00094 D00094 💬 |
Tretinoin | 002 [5] 2 , 63, 75, 94, 231 💬 |
1277 | Valine, leucine and isoleucine degradation 💬 1 gene, 2 drugs (DrugBank) and 18 diseases |
ABAT [1] ABAT 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [16] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬 |
1278 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
ADORA2A [1] ADORA2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1279 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
ADORA2A [1] ADORA2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1280 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
1281 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D06623 D06623 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
1282 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
1283 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
PTGIR [1] PTGIR 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
1284 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [2] 2 , 51 💬 |
1285 | VEGF signaling pathway 💬 20 genes, 48 drugs (DrugBank) and 84 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
1286 | VEGF signaling pathway 💬 20 genes, 48 drugs (DrugBank) and 84 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1287 | VEGF signaling pathway 💬 20 genes, 48 drugs (DrugBank) and 84 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1288 | VEGF signaling pathway 💬 20 genes, 48 drugs (DrugBank) and 84 diseases |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [9] 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬 |
1289 | VEGF signaling pathway 💬 20 genes, 48 drugs (DrugBank) and 84 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
1290 | Vibrio cholerae infection 💬 3 genes, 9 drugs (DrugBank) and 7 diseases |
KCNQ1 [1] KCNQ1 💬 |
D09569 D09569 💬 |
Ezogabine | 002 [2] 2 , 144 💬 |
1291 | Viral carcinogenesis 💬 27 genes, 19 drugs (DrugBank) and 36 diseases |
HLA-A [6] HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
1292 | Viral carcinogenesis 💬 27 genes, 19 drugs (DrugBank) and 36 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
1293 | Viral myocarditis 💬 29 genes, 18 drugs (DrugBank) and 46 diseases |
ABL1 [1] ABL1 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
1294 | Viral myocarditis 💬 29 genes, 18 drugs (DrugBank) and 46 diseases |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
1295 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 27 drugs (DrugBank) and 58 diseases |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [7] 2 , 50, 65, 66, 97, 222, 228 💬 |
1296 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 27 drugs (DrugBank) and 58 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
1297 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 27 drugs (DrugBank) and 58 diseases |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
1298 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 27 drugs (DrugBank) and 58 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1299 | Wnt signaling pathway 💬 8 genes, 7 drugs (DrugBank) and 56 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1300 | Wnt signaling pathway 💬 8 genes, 7 drugs (DrugBank) and 56 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1301 | Wnt signaling pathway 💬 8 genes, 7 drugs (DrugBank) and 56 diseases |
ROCK2 [1] ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [2] 2 , 51 💬 |
1302 | Yersinia infection 💬 20 genes, 32 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
1303 | Yersinia infection 💬 20 genes, 32 drugs (DrugBank) and 66 diseases |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [2] 2 , 51 💬 |
1304 | Yersinia infection 💬 20 genes, 32 drugs (DrugBank) and 66 diseases |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
1305 | Yersinia infection 💬 20 genes, 32 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |