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Target Gene/Pathway💬 Info on mouse-over

e.g. Sirolimus, Adalimumab, MAP2K

ABCDEFGH I JKLMNOPQRSTUVWXYZother

63 / 286 pathways

No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related		 KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adipocytokine signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
2 Adipocytokine signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
3 Aldosterone-regulated sodium reabsorption 💬
 [1] NR3C2 💬 D00443 💬 Spironolactone [7] 58, 67, 86, 113, 210, 218, 225 💬
4 Aldosterone-regulated sodium reabsorption 💬
 [3] SCNN1A, SCNN1B, SCNN1G 💬 D00649 💬 Amiloride [3] 13, 225, 299 💬
5 Aldosterone-regulated sodium reabsorption 💬
 [3] SCNN1A, SCNN1B, SCNN1G 💬 D07447 💬 Amiloride [3] 13, 225, 299 💬
6 Alzheimer disease 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
7 Alzheimer disease 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
8 Alzheimer disease 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
9 AMPK signaling pathway 💬
 [1] HMGCR 💬 D00887 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
10 AMPK signaling pathway 💬
 [1] HMGCR 💬 D07474 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
11 AMPK signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
12 AMPK signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
13 Apelin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
14 Apelin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
15 Arachidonic acid metabolism 💬
 [2] PTGS1, PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
16 Arachidonic acid metabolism 💬
 [2] PTGS1, PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
17 Arachidonic acid metabolism 💬
 [2] PTGS1, PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
18 Autophagy - animal 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
19 Autophagy - animal 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
20 Bile secretion 💬
 [1] CA2 💬 D00218 💬 Acetazolamide [7] 13, 86, 90, 115, 155, 225, 230 💬
21 Bile secretion 💬
 [1] CA2 💬 D01196 💬 Acetazolamide [7] 13, 86, 90, 115, 155, 225, 230 💬
22 Bile secretion 💬
 [1] HMGCR 💬 D00887 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
23 Bile secretion 💬
 [1] HMGCR 💬 D07474 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
24 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
25 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
26 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
27 cGMP-PKG signaling pathway 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
28 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 D02229 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
29 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 D08514 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
30 Chemical carcinogenesis 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
31 Chemical carcinogenesis 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
32 Chemical carcinogenesis 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
33 Circadian entrainment 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
34 Circadian rhythm 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
35 Circadian rhythm 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
36 Collecting duct acid secretion 💬
 [2] ATP4A, ATP4B 💬 D00455 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
37 Collecting duct acid secretion 💬
 [2] ATP4A, ATP4B 💬 D01207 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
38 Collecting duct acid secretion 💬
 [2] ATP4A, ATP4B 💬 D05259 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
39 Collecting duct acid secretion 💬
 [2] ATP4A, ATP4B 💬 D05261 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
40 Collecting duct acid secretion 💬
 [1] CA2 💬 D00218 💬 Acetazolamide [7] 13, 86, 90, 115, 155, 225, 230 💬
41 Collecting duct acid secretion 💬
 [1] CA2 💬 D01196 💬 Acetazolamide [7] 13, 86, 90, 115, 155, 225, 230 💬
42 Complement and coagulation cascades 💬
 [1] F8 💬 D00291 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
43 Complement and coagulation cascades 💬
 [1] F8 💬 D02235 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
44 Fluid shear stress and atherosclerosis 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
45 Fluid shear stress and atherosclerosis 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
46 FoxO signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
47 FoxO signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
48 Gap junction 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
49 Gastric acid secretion 💬
 [2] ATP4A, ATP4B 💬 D00455 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
50 Gastric acid secretion 💬
 [2] ATP4A, ATP4B 💬 D01207 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
51 Gastric acid secretion 💬
 [2] ATP4A, ATP4B 💬 D05259 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
52 Gastric acid secretion 💬
 [2] ATP4A, ATP4B 💬 D05261 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
53 Gastric acid secretion 💬
 [1] CA2 💬 D00218 💬 Acetazolamide [7] 13, 86, 90, 115, 155, 225, 230 💬
54 Gastric acid secretion 💬
 [1] CA2 💬 D01196 💬 Acetazolamide [7] 13, 86, 90, 115, 155, 225, 230 💬
55 Glucagon signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
56 Glucagon signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
57 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
58 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
59 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
60 Human papillomavirus infection 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
61 Human papillomavirus infection 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
62 Human papillomavirus infection 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
63 Hypertrophic cardiomyopathy 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
64 Hypertrophic cardiomyopathy 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
65 IL-17 signaling pathway 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
66 IL-17 signaling pathway 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
67 IL-17 signaling pathway 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
68 Insulin resistance 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
69 Insulin resistance 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
70 Insulin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
71 Insulin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
72 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
73 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
74 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
75 Leishmaniasis 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
76 Leishmaniasis 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
77 Leishmaniasis 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
78 Long-term depression 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
79 Longevity regulating pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
80 Longevity regulating pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
81 Longevity regulating pathway - multiple species 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
82 Longevity regulating pathway - multiple species 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
83 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D00455 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
84 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D01207 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
85 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D05259 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
86 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D05261 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
87 Metabolic pathways 💬
 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 D00218 💬 Acetazolamide [7] 13, 86, 90, 115, 155, 225, 230 💬
88 Metabolic pathways 💬
 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 D01196 💬 Acetazolamide [7] 13, 86, 90, 115, 155, 225, 230 💬
89 Metabolic pathways 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
90 Metabolic pathways 💬
 [1] HMGCR 💬 D00887 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
91 Metabolic pathways 💬
 [1] HMGCR 💬 D07474 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
92 Metabolic pathways 💬
 [1] PDE5A 💬 D02229 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
93 Metabolic pathways 💬
 [1] PDE5A 💬 D08514 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
94 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
95 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
96 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
97 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
98 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
99 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
100 mTOR signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
101 mTOR signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
102 Neuroactive ligand-receptor interaction 💬
 [1] AVPR2 💬 D00291 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
103 Neuroactive ligand-receptor interaction 💬
 [1] AVPR2 💬 D02235 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
104 Neuroactive ligand-receptor interaction 💬
 [1] AVPR2 💬 D01213 💬 Tolvaptan [3] 67, 72, 225 💬
105 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
106 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
107 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
108 Nitrogen metabolism 💬
 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 D00218 💬 Acetazolamide [7] 13, 86, 90, 115, 155, 225, 230 💬
109 Nitrogen metabolism 💬
 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 D01196 💬 Acetazolamide [7] 13, 86, 90, 115, 155, 225, 230 💬
110 Non-alcoholic fatty liver disease 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
111 Non-alcoholic fatty liver disease 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
112 Ovarian steroidogenesis 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
113 Ovarian steroidogenesis 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
114 Ovarian steroidogenesis 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
115 Oxidative phosphorylation 💬
 [2] ATP4A, ATP4B 💬 D00455 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
116 Oxidative phosphorylation 💬
 [2] ATP4A, ATP4B 💬 D01207 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
117 Oxidative phosphorylation 💬
 [2] ATP4A, ATP4B 💬 D05259 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
118 Oxidative phosphorylation 💬
 [2] ATP4A, ATP4B 💬 D05261 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
119 Oxytocin signaling pathway 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
120 Oxytocin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
121 Oxytocin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
122 Oxytocin signaling pathway 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
123 Oxytocin signaling pathway 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
124 Oxytocin signaling pathway 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
125 Pancreatic secretion 💬
 [1] CA2 💬 D00218 💬 Acetazolamide [7] 13, 86, 90, 115, 155, 225, 230 💬
126 Pancreatic secretion 💬
 [1] CA2 💬 D01196 💬 Acetazolamide [7] 13, 86, 90, 115, 155, 225, 230 💬
127 Pathways in cancer 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
128 Pathways in cancer 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
129 Pathways in cancer 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
130 Pathways of neurodegeneration - multiple diseases 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
131 Pathways of neurodegeneration - multiple diseases 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
132 Pathways of neurodegeneration - multiple diseases 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
133 Phospholipase D signaling pathway 💬
 [1] AVPR2 💬 D00291 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
134 Phospholipase D signaling pathway 💬
 [1] AVPR2 💬 D02235 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
135 Phospholipase D signaling pathway 💬
 [1] AVPR2 💬 D01213 💬 Tolvaptan [3] 67, 72, 225 💬
136 PI3K-Akt signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
137 PI3K-Akt signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
138 Platelet activation 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
139 Platelet activation 💬
 [1] PTGS1 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
140 Platelet activation 💬
 [1] PTGS1 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
141 Platelet activation 💬
 [1] PTGS1 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
142 Proximal tubule bicarbonate reclamation 💬
 [2] CA2, CA4 💬 D00218 💬 Acetazolamide [7] 13, 86, 90, 115, 155, 225, 230 💬
143 Proximal tubule bicarbonate reclamation 💬
 [2] CA2, CA4 💬 D01196 💬 Acetazolamide [7] 13, 86, 90, 115, 155, 225, 230 💬
144 Purine metabolism 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
145 Purine metabolism 💬
 [1] PDE5A 💬 D02229 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
146 Purine metabolism 💬
 [1] PDE5A 💬 D08514 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
147 Regulation of lipolysis in adipocytes 💬
 [2] PTGS1, PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
148 Regulation of lipolysis in adipocytes 💬
 [2] PTGS1, PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
149 Regulation of lipolysis in adipocytes 💬
 [2] PTGS1, PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
150 Renin secretion 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
151 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
152 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
153 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
154 Salivary secretion 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
155 Serotonergic synapse 💬
 [2] PTGS1, PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
156 Serotonergic synapse 💬
 [2] PTGS1, PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
157 Serotonergic synapse 💬
 [2] PTGS1, PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
158 Small cell lung cancer 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
159 Small cell lung cancer 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
160 Small cell lung cancer 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
161 Taste transduction 💬
 [3] SCNN1A, SCNN1B, SCNN1G 💬 D00649 💬 Amiloride [3] 13, 225, 299 💬
162 Taste transduction 💬
 [3] SCNN1A, SCNN1B, SCNN1G 💬 D07447 💬 Amiloride [3] 13, 225, 299 💬
163 Terpenoid backbone biosynthesis 💬
 [1] HMGCR 💬 D00887 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
164 Terpenoid backbone biosynthesis 💬
 [1] HMGCR 💬 D07474 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
165 Thermogenesis 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
166 Thermogenesis 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
167 Tight junction 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
168 Tight junction 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
169 TNF signaling pathway 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
170 TNF signaling pathway 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
171 TNF signaling pathway 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
172 Vascular smooth muscle contraction 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
173 Vasopressin-regulated water reabsorption 💬
 [1] AVPR2 💬 D00291 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
174 Vasopressin-regulated water reabsorption 💬
 [1] AVPR2 💬 D02235 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
175 Vasopressin-regulated water reabsorption 💬
 [1] AVPR2 💬 D01213 💬 Tolvaptan [3] 67, 72, 225 💬
176 VEGF signaling pathway 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
177 VEGF signaling pathway 💬
 [1] PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
178 VEGF signaling pathway 💬
 [1] PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬

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