Target Gene/Pathway💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
1 | Acute myeloid leukemia 💬 15 genes, 25 drugs (DrugBank) and 59 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
2 | Adherens junction 💬 9 genes, 18 drugs (DrugBank) and 24 diseases |
FGFR1 [1] FGFR1 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
3 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
JAK2 [1] JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
4 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
5 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
6 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
7 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
ADRB2 [1] ADRB2 💬 |
D01373 D01373 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
8 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
ADRB2 [1] ADRB2 💬 |
D05277 D05277 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
9 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
ADRB2 [1] ADRB2 💬 |
D07990 D07990 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
10 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
ADRB2 [1] ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 [14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬 |
11 | African trypanosomiasis 💬 7 genes, 19 drugs (DrugBank) and 57 diseases |
IL10 [4] IL10, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
12 | African trypanosomiasis 💬 7 genes, 19 drugs (DrugBank) and 57 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
13 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
CCL2 [5] CCL2, IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
14 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
JAK2 [1] JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
15 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
16 | Allograft rejection 💬 30 genes, 22 drugs (DrugBank) and 57 diseases |
IL10 [2] IL10, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
17 | Allograft rejection 💬 30 genes, 22 drugs (DrugBank) and 57 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
18 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
19 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
20 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
21 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
22 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
23 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
PSMB5 [1] PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 [15] 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬 |
24 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
25 | Amoebiasis 💬 17 genes, 25 drugs (DrugBank) and 62 diseases |
IL10 [4] IL10, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
26 | Amoebiasis 💬 17 genes, 25 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
27 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
28 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
29 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
30 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
31 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
32 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
33 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
34 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
35 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
PSMB5 [1] PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 [15] 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬 |
36 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
37 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
38 | Antifolate resistance 💬 7 genes, 20 drugs (DrugBank) and 64 diseases |
IL1B [3] IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
39 | Antifolate resistance 💬 7 genes, 20 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
40 | Antigen processing and presentation 💬 23 genes, 15 drugs (DrugBank) and 53 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
41 | Antigen processing and presentation 💬 23 genes, 15 drugs (DrugBank) and 53 diseases |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
42 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
43 | Apoptosis 💬 14 genes, 23 drugs (DrugBank) and 54 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
44 | Apoptosis 💬 14 genes, 23 drugs (DrugBank) and 54 diseases |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
45 | Asthma 💬 21 genes, 21 drugs (DrugBank) and 55 diseases |
IL10 [2] IL10, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
46 | Asthma 💬 21 genes, 21 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
47 | Autoimmune thyroid disease 💬 41 genes, 14 drugs (DrugBank) and 37 diseases |
IL10 [1] IL10 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
48 | Autophagy - animal 💬 13 genes, 15 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
49 | Autophagy - other 💬 1 gene, 3 drugs (DrugBank) and 41 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
50 | Axon guidance 💬 21 genes, 19 drugs (DrugBank) and 65 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
51 | Axon guidance 💬 21 genes, 19 drugs (DrugBank) and 65 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
52 | Axon guidance 💬 21 genes, 19 drugs (DrugBank) and 65 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
53 | B cell receptor signaling pathway 💬 16 genes, 19 drugs (DrugBank) and 63 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
54 | B cell receptor signaling pathway 💬 16 genes, 19 drugs (DrugBank) and 63 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
55 | B cell receptor signaling pathway 💬 16 genes, 19 drugs (DrugBank) and 63 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
56 | Bladder cancer 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
FGFR3 [1] FGFR3 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
57 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
FGFR1 [2] FGFR1, FLT4 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
58 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
59 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
IL10 [4] IL10, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
60 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
61 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
62 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
63 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
64 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADRB2 [1] ADRB2 💬 |
D01373 D01373 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
65 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADRB2 [1] ADRB2 💬 |
D05277 D05277 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
66 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADRB2 [1] ADRB2 💬 |
D07990 D07990 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
67 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADRB2 [1] ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 [14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬 |
68 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
CYSLTR1 [1] CYSLTR1 💬 |
D00529 D00529 💬 |
Montelukast | 013 [5] 13, 46, 85, 98, 228 💬 |
69 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
CYSLTR1 [1] CYSLTR1 💬 |
D08229 D08229 💬 |
Montelukast | 013 [5] 13, 46, 85, 98, 228 💬 |
70 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
71 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
72 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
73 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
74 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
ADRB2 [1] ADRB2 💬 |
D01373 D01373 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
75 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
ADRB2 [1] ADRB2 💬 |
D05277 D05277 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
76 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
ADRB2 [1] ADRB2 💬 |
D07990 D07990 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
77 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
ADRB2 [1] ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 [14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬 |
78 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
IL1A [2] IL1A, IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
79 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
80 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
81 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
82 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
83 | Central carbon metabolism in cancer 💬 18 genes, 24 drugs (DrugBank) and 55 diseases |
FGFR1 [5] FGFR1, FGFR2, FGFR3, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
84 | Central carbon metabolism in cancer 💬 18 genes, 24 drugs (DrugBank) and 55 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
85 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRB2 [1] ADRB2 💬 |
D01373 D01373 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
86 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRB2 [1] ADRB2 💬 |
D05277 D05277 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
87 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRB2 [1] ADRB2 💬 |
D07990 D07990 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
88 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRB2 [1] ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 [14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬 |
89 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
90 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
91 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
92 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
CCL2 [5] CCL2, IL10, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
93 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 |
94 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
95 | Chemokine signaling pathway 💬 20 genes, 23 drugs (DrugBank) and 41 diseases |
CCL2 [1] CCL2 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
96 | Chemokine signaling pathway 💬 20 genes, 23 drugs (DrugBank) and 41 diseases |
JAK2 [1] JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
97 | Choline metabolism in cancer 💬 10 genes, 20 drugs (DrugBank) and 51 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
98 | Choline metabolism in cancer 💬 10 genes, 20 drugs (DrugBank) and 51 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
99 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
JAK2 [1] JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
100 | Colorectal cancer 💬 14 genes, 19 drugs (DrugBank) and 49 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
101 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
102 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
103 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
JAK1 [1] JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
104 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
105 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
CCL2 [6] CCL2, IL10, IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
106 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 |
107 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [7] 2 , 50, 65, 66, 97, 222, 228 💬 |
108 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
LTA [2] LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
109 | Cytosolic DNA-sensing pathway 💬 16 genes, 10 drugs (DrugBank) and 25 diseases |
IL1B [2] IL1B, IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
110 | Diabetic cardiomyopathy 💬 21 genes, 38 drugs (DrugBank) and 72 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
111 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
112 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
113 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
PPP3CA [3] PPP3CA, PPP3CB, PPP3CC 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
114 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
PPP3CA [3] PPP3CA, PPP3CB, PPP3CC 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
115 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
PPP3CA [3] PPP3CA, PPP3CB, PPP3CC 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
116 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 46 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05096 D05096 💬 |
Mycophenolic acid | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 |
117 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
FGFR2 [5] FGFR2, FGFR3, KDR, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
118 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
IL6 [1] IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
119 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
120 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
JAK1 [2] JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
121 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
122 | Endocrine and other factor-regulated calcium reabsorption 💬 7 genes, 25 drugs (DrugBank) and 49 diseases |
VDR [1] VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 [23] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 162, 202, 228, 271, 298, 299 💬 |
123 | Endocrine resistance 💬 19 genes, 37 drugs (DrugBank) and 59 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
124 | Endocytosis 💬 20 genes, 27 drugs (DrugBank) and 50 diseases |
FGFR2 [3] FGFR2, FGFR3, PDGFRA 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
125 | Endocytosis 💬 20 genes, 27 drugs (DrugBank) and 50 diseases |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [7] 2 , 50, 65, 66, 97, 222, 228 💬 |
126 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
IL6 [2] IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
127 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
128 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
JAK1 [1] JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
129 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
130 | ErbB signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 51 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
131 | Fc epsilon RI signaling pathway 💬 19 genes, 35 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
132 | Fc epsilon RI signaling pathway 💬 19 genes, 35 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
133 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
CCL2 [4] CCL2, IL1A, IL1B, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
134 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
KDR [1] KDR 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
135 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
136 | Focal adhesion 💬 26 genes, 37 drugs (DrugBank) and 42 diseases |
FLT1 [5] FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
137 | FoxO signaling pathway 💬 24 genes, 34 drugs (DrugBank) and 53 diseases |
IL10 [2] IL10, IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
138 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
139 | Gastric cancer 💬 20 genes, 29 drugs (DrugBank) and 57 diseases |
FGFR2 [1] FGFR2 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
140 | Gastric cancer 💬 20 genes, 29 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
141 | Glioma 💬 12 genes, 24 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
142 | Glioma 💬 12 genes, 24 drugs (DrugBank) and 56 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
143 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
144 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
145 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
146 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
147 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
148 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
149 | Graft-versus-host disease 💬 27 genes, 22 drugs (DrugBank) and 61 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
150 | Graft-versus-host disease 💬 27 genes, 22 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
151 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
JAK2 [1] JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
152 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
153 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
154 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [7] 2 , 50, 65, 66, 97, 222, 228 💬 |
155 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
156 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
IL6 [2] IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
157 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
158 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
JAK1 [2] JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
159 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
160 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
161 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
JAK1 [1] JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
162 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
163 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
164 | Hepatocellular carcinoma 💬 18 genes, 25 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
165 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
166 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 |
167 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
168 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
JAK1 [2] JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
169 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
LTA [2] LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
170 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
171 | HIF-1 signaling pathway 💬 20 genes, 40 drugs (DrugBank) and 73 diseases |
FLT1 [1] FLT1 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
172 | HIF-1 signaling pathway 💬 20 genes, 40 drugs (DrugBank) and 73 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 |
173 | HIF-1 signaling pathway 💬 20 genes, 40 drugs (DrugBank) and 73 diseases |
IL6 [1] IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
174 | HIF-1 signaling pathway 💬 20 genes, 40 drugs (DrugBank) and 73 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
175 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
176 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
177 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
JAK1 [1] JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
178 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
179 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
PDGFRA [1] PDGFRA 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
180 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
181 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
182 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
183 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
184 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
185 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
186 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
187 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
188 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
189 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
190 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
191 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
JAK1 [1] JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
192 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
193 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
PDGFRB [1] PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
194 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
195 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
196 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [7] 2 , 50, 65, 66, 97, 222, 228 💬 |
197 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
IL6 [2] IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
198 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
199 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
JAK1 [1] JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
200 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
LTA [2] LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
201 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
202 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
203 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
204 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
205 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
PSMB5 [1] PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 [15] 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬 |
206 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
IL6 [2] IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
207 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
208 | IL-17 signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 79 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
209 | IL-17 signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 79 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
210 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 |
211 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
IL10 [5] IL10, IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
212 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
213 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
IL1B [1] IL1B 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
214 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
CCL2 [5] CCL2, IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
215 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 |
216 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
217 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
JAK1 [2] JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
218 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
219 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
IL6 [2] IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
220 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
221 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
222 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
223 | Intestinal immune network for IgA production 💬 27 genes, 23 drugs (DrugBank) and 47 diseases |
IL10 [2] IL10, IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
224 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 |
225 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
IL10 [2] IL10, IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
226 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [7] 2 , 50, 65, 66, 97, 222, 228 💬 |
227 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
228 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
JAK1 [2] JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
229 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
230 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
231 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
IFNGR1 [1] IFNGR1 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 |
232 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
IL6 [1] IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
233 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
234 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
JAK1 [2] JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
235 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
236 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
237 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
238 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
239 | Legionellosis 💬 7 genes, 19 drugs (DrugBank) and 58 diseases |
IL1B [3] IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
240 | Legionellosis 💬 7 genes, 19 drugs (DrugBank) and 58 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
241 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 |
242 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
IL10 [4] IL10, IL1A, IL1B, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
243 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
244 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
JAK1 [2] JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
245 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
246 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
247 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
248 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
249 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
250 | Longevity regulating pathway - multiple species 💬 10 genes, 13 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
251 | Malaria 💬 14 genes, 25 drugs (DrugBank) and 62 diseases |
CCL2 [5] CCL2, IL10, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
252 | Malaria 💬 14 genes, 25 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
253 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
254 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
IL1A [3] IL1A, IL1B, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
255 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
256 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
257 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
258 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
259 | Measles 💬 36 genes, 37 drugs (DrugBank) and 49 diseases |
IL1A [3] IL1A, IL1B, IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
260 | Measles 💬 36 genes, 37 drugs (DrugBank) and 49 diseases |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [7] 2 , 50, 65, 66, 97, 222, 228 💬 |
261 | Measles 💬 36 genes, 37 drugs (DrugBank) and 49 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
262 | Measles 💬 36 genes, 37 drugs (DrugBank) and 49 diseases |
JAK1 [1] JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
263 | Melanoma 💬 13 genes, 23 drugs (DrugBank) and 34 diseases |
FGFR1 [3] FGFR1, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
264 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05096 D05096 💬 |
Mycophenolic acid | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 |
265 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
FGFR3 [3] FGFR3, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
266 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
267 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 37 diseases |
VDR [1] VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 [23] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 162, 202, 228, 271, 298, 299 💬 |
268 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
269 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
270 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
271 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 |
272 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
273 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
274 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
275 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
276 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
277 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 |
278 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
IL1A [3] IL1A, IL1B, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
279 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
280 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
JAK1 [2] JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
281 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
282 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRB2 [1] ADRB2 💬 |
D01373 D01373 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
283 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRB2 [1] ADRB2 💬 |
D05277 D05277 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
284 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRB2 [1] ADRB2 💬 |
D07990 D07990 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
285 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRB2 [1] ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 [14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬 |
286 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
CYSLTR1 [1] CYSLTR1 💬 |
D00529 D00529 💬 |
Montelukast | 013 [5] 13, 46, 85, 98, 228 💬 |
287 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
CYSLTR1 [1] CYSLTR1 💬 |
D08229 D08229 💬 |
Montelukast | 013 [5] 13, 46, 85, 98, 228 💬 |
288 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00246 D00246 💬 |
Budesonide | 066 [9] 66, 93, 94, 95, 96, 97, 98, 228, 299 💬 |
289 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D07981 D07981 💬 |
Fluticasone | 098 [3] 98, 228, 299 💬 |
290 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D01708 D01708 💬 |
Fluticasone propionate | 098 [2] 98, 228 💬 |
291 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00473 D00473 💬 |
Prednisone | 002 [47] 2 , 6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 93, 95, 96, 97, 113, 127, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬 |
292 | Neutrophil extracellular trap formation 💬 32 genes, 27 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
293 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
IL1B [2] IL1B, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
294 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
LTA [2] LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
295 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
296 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
297 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
JAK1 [1] JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
298 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
299 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
300 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
301 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
302 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
303 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
304 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 |
305 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
IL1A [3] IL1A, IL1B, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
306 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
307 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
JAK1 [1] JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
308 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
309 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
310 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
311 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
312 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
313 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
314 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
315 | Pancreatic cancer 💬 16 genes, 29 drugs (DrugBank) and 64 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
316 | Pancreatic cancer 💬 16 genes, 29 drugs (DrugBank) and 64 diseases |
JAK1 [1] JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
317 | Pancreatic cancer 💬 16 genes, 29 drugs (DrugBank) and 64 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
318 | Parathyroid hormone synthesis, secretion and action 💬 19 genes, 40 drugs (DrugBank) and 58 diseases |
FGFR1 [1] FGFR1 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
319 | Parathyroid hormone synthesis, secretion and action 💬 19 genes, 40 drugs (DrugBank) and 58 diseases |
VDR [1] VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 [23] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 162, 202, 228, 271, 298, 299 💬 |
320 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
PSMB5 [1] PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 [15] 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬 |
321 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
IL1B [3] IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
322 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
323 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
FGFR1 [6] FGFR1, FGFR2, FGFR3, FLT4, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
324 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 |
325 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [7] 2 , 50, 65, 66, 97, 222, 228 💬 |
326 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
IL6 [1] IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
327 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
328 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
JAK1 [2] JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
329 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
330 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
331 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
332 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
333 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
334 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
335 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
PSMB5 [1] PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 [15] 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬 |
336 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
337 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 |
338 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
339 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
JAK1 [2] JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
340 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
341 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
342 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
343 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
344 | Pertussis 💬 16 genes, 32 drugs (DrugBank) and 65 diseases |
IL10 [5] IL10, IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
345 | Pertussis 💬 16 genes, 32 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
346 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
347 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
348 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
349 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [7] 2 , 50, 65, 66, 97, 222, 228 💬 |
350 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
IL6 [1] IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
351 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
352 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
JAK1 [2] JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
353 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
354 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
IL1A [4] IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
355 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
356 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
357 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
358 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
PSMB5 [1] PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 [15] 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬 |
359 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
360 | Prolactin signaling pathway 💬 18 genes, 33 drugs (DrugBank) and 48 diseases |
JAK2 [1] JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
361 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
FGFR1 [4] FGFR1, FGFR2, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
362 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
363 | Proteasome 💬 2 genes, 5 drugs (DrugBank) and 17 diseases |
PSMB5 [1] PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 [15] 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬 |
364 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
FGFR1 [2] FGFR1, KDR 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
365 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
366 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
367 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
368 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05096 D05096 💬 |
Mycophenolic acid | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 |
369 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
370 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
371 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
FGFR1 [5] FGFR1, FGFR2, FGFR3, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
372 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
ADRB2 [1] ADRB2 💬 |
D01373 D01373 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
373 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
ADRB2 [1] ADRB2 💬 |
D05277 D05277 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
374 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
ADRB2 [1] ADRB2 💬 |
D07990 D07990 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
375 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
ADRB2 [1] ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 [14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬 |
376 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ADRB2 [1] ADRB2 💬 |
D01373 D01373 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
377 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ADRB2 [1] ADRB2 💬 |
D05277 D05277 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
378 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ADRB2 [1] ADRB2 💬 |
D07990 D07990 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
379 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ADRB2 [1] ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 [14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬 |
380 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
381 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
382 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
383 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
CCL2 [5] CCL2, IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
384 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
FLT1 [1] FLT1 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
385 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
386 | RIG-I-like receptor signaling pathway 💬 21 genes, 17 drugs (DrugBank) and 53 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
387 | RIG-I-like receptor signaling pathway 💬 21 genes, 17 drugs (DrugBank) and 53 diseases |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
388 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
ADRB2 [1] ADRB2 💬 |
D01373 D01373 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
389 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
ADRB2 [1] ADRB2 💬 |
D05277 D05277 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
390 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
ADRB2 [1] ADRB2 💬 |
D07990 D07990 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
391 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
ADRB2 [1] ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 [14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬 |
392 | Salmonella infection 💬 25 genes, 32 drugs (DrugBank) and 62 diseases |
IL1B [3] IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
393 | Salmonella infection 💬 25 genes, 32 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
394 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
IL1B [2] IL1B, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
395 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
396 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
397 | Signaling pathways regulating pluripotency of stem cells 💬 20 genes, 24 drugs (DrugBank) and 43 diseases |
FGFR1 [3] FGFR1, FGFR2, FGFR3 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
398 | Signaling pathways regulating pluripotency of stem cells 💬 20 genes, 24 drugs (DrugBank) and 43 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
399 | Signaling pathways regulating pluripotency of stem cells 💬 20 genes, 24 drugs (DrugBank) and 43 diseases |
JAK1 [2] JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
400 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
401 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
402 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
403 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
PSMB5 [1] PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 [15] 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬 |
404 | Staphylococcus aureus infection 💬 24 genes, 15 drugs (DrugBank) and 32 diseases |
IL10 [1] IL10 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
405 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
IL10 [2] IL10, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
406 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
407 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
IL10 [2] IL10, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
408 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
409 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
410 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
411 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
412 | TGF-beta signaling pathway 💬 11 genes, 20 drugs (DrugBank) and 54 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
413 | TGF-beta signaling pathway 💬 11 genes, 20 drugs (DrugBank) and 54 diseases |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
414 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 |
415 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [7] 2 , 50, 65, 66, 97, 222, 228 💬 |
416 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
417 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
JAK1 [2] JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
418 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
419 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
420 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
421 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 |
422 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IL1B [2] IL1B, IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
423 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [7] 2 , 50, 65, 66, 97, 222, 228 💬 |
424 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
425 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
JAK1 [2] JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
426 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
427 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
428 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
429 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
430 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
FGFR1 [1] FGFR1 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
431 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
432 | Thyroid hormone signaling pathway 💬 22 genes, 35 drugs (DrugBank) and 61 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
433 | TNF signaling pathway 💬 18 genes, 51 drugs (DrugBank) and 79 diseases |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
434 | TNF signaling pathway 💬 18 genes, 51 drugs (DrugBank) and 79 diseases |
LTA [2] LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
435 | Toll-like receptor signaling pathway 💬 34 genes, 39 drugs (DrugBank) and 64 diseases |
IL1B [3] IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
436 | Toll-like receptor signaling pathway 💬 34 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
437 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 |
438 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
IL10 [2] IL10, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
439 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
440 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
JAK1 [2] JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
441 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
442 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
FLT1 [1] FLT1 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
443 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
IL6 [1] IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
444 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 |
445 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
IL10 [5] IL10, IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
446 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
447 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
JAK1 [2] JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
448 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
449 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
450 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
451 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
452 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
VDR [1] VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 [23] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 162, 202, 228, 271, 298, 299 💬 |
453 | Type I diabetes mellitus 💬 31 genes, 23 drugs (DrugBank) and 69 diseases |
IL1A [3] IL1A, IL1B, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
454 | Type I diabetes mellitus 💬 31 genes, 23 drugs (DrugBank) and 69 diseases |
LTA [2] LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
455 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
456 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
457 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
458 | VEGF signaling pathway 💬 20 genes, 48 drugs (DrugBank) and 84 diseases |
KDR [1] KDR 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
459 | VEGF signaling pathway 💬 20 genes, 48 drugs (DrugBank) and 84 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
460 | VEGF signaling pathway 💬 20 genes, 48 drugs (DrugBank) and 84 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
461 | VEGF signaling pathway 💬 20 genes, 48 drugs (DrugBank) and 84 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
462 | Viral carcinogenesis 💬 27 genes, 19 drugs (DrugBank) and 36 diseases |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
463 | Viral carcinogenesis 💬 27 genes, 19 drugs (DrugBank) and 36 diseases |
JAK1 [1] JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
464 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 27 drugs (DrugBank) and 58 diseases |
CCL2 [4] CCL2, IL10, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
465 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 27 drugs (DrugBank) and 58 diseases |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [7] 2 , 50, 65, 66, 97, 222, 228 💬 |
466 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 27 drugs (DrugBank) and 58 diseases |
LTA [2] LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
467 | Wnt signaling pathway 💬 8 genes, 7 drugs (DrugBank) and 56 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
468 | Wnt signaling pathway 💬 8 genes, 7 drugs (DrugBank) and 56 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
469 | Wnt signaling pathway 💬 8 genes, 7 drugs (DrugBank) and 56 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
470 | Yersinia infection 💬 20 genes, 32 drugs (DrugBank) and 66 diseases |
CCL2 [5] CCL2, IL10, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 034 [10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
471 | Yersinia infection 💬 20 genes, 32 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |