Target Gene/Pathway💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
1 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
2 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
3 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
CA2 [1] CA2 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
4 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
CA2 [1] CA2 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
5 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
ESR1 [2] ESR1, PGR 💬 |
D02367 D02367 💬 |
Desogestrel | 230 [1] 230 💬 |
6 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
DRD2 [1] DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
7 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
DRD2 [1] DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
8 | Carbohydrate digestion and absorption 💬 10 genes, 16 drugs (DrugBank) and 28 diseases |
TAS1R2 [2] TAS1R2, TAS1R3 💬 |
D02381 D02381 💬 |
Aspartame | 006 [5] 6 , 13, 67, 86, 230 💬 |
9 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
DRD2 [1] DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
10 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
DRD2 [1] DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
11 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
CA2 [1] CA2 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
12 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
CA2 [1] CA2 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
13 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
DRD2 [1] DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
14 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
DRD2 [1] DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
15 | Endocrine and other factor-regulated calcium reabsorption 💬 7 genes, 25 drugs (DrugBank) and 49 diseases |
ESR1 [1] ESR1 💬 |
D02367 D02367 💬 |
Desogestrel | 230 [1] 230 💬 |
16 | Endocrine resistance 💬 19 genes, 37 drugs (DrugBank) and 59 diseases |
ESR1 [1] ESR1 💬 |
D02367 D02367 💬 |
Desogestrel | 230 [1] 230 💬 |
17 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
ESR1 [2] ESR1, PGR 💬 |
D02367 D02367 💬 |
Desogestrel | 230 [1] 230 💬 |
18 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
DRD2 [1] DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
19 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
DRD2 [1] DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
20 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
CA2 [1] CA2 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
21 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
CA2 [1] CA2 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
22 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
23 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
24 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
DRD2 [1] DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
25 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
DRD2 [1] DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
26 | Nitrogen metabolism 💬 14 genes, 5 drugs (DrugBank) and 16 diseases |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
27 | Nitrogen metabolism 💬 14 genes, 5 drugs (DrugBank) and 16 diseases |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
28 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
PGR [1] PGR 💬 |
D02367 D02367 💬 |
Desogestrel | 230 [1] 230 💬 |
29 | Pancreatic secretion 💬 10 genes, 34 drugs (DrugBank) and 33 diseases |
CA2 [1] CA2 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
30 | Pancreatic secretion 💬 10 genes, 34 drugs (DrugBank) and 33 diseases |
CA2 [1] CA2 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
31 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
DRD2 [1] DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
32 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
DRD2 [1] DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
33 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
ESR1 [1] ESR1 💬 |
D02367 D02367 💬 |
Desogestrel | 230 [1] 230 💬 |
34 | Progesterone-mediated oocyte maturation 💬 14 genes, 32 drugs (DrugBank) and 37 diseases |
PGR [1] PGR 💬 |
D02367 D02367 💬 |
Desogestrel | 230 [1] 230 💬 |
35 | Prolactin signaling pathway 💬 18 genes, 33 drugs (DrugBank) and 48 diseases |
ESR1 [1] ESR1 💬 |
D02367 D02367 💬 |
Desogestrel | 230 [1] 230 💬 |
36 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
ESR1 [1] ESR1 💬 |
D02367 D02367 💬 |
Desogestrel | 230 [1] 230 💬 |
37 | Proximal tubule bicarbonate reclamation 💬 6 genes, 6 drugs (DrugBank) and 17 diseases |
CA2 [2] CA2, CA4 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
38 | Proximal tubule bicarbonate reclamation 💬 6 genes, 6 drugs (DrugBank) and 17 diseases |
CA2 [2] CA2, CA4 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
39 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
DRD2 [1] DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
40 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
DRD2 [1] DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
41 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
TAS1R2 [2] TAS1R2, TAS1R3 💬 |
D02381 D02381 💬 |
Aspartame | 006 [5] 6 , 13, 67, 86, 230 💬 |
42 | Thyroid hormone signaling pathway 💬 22 genes, 35 drugs (DrugBank) and 61 diseases |
ESR1 [1] ESR1 💬 |
D02367 D02367 💬 |
Desogestrel | 230 [1] 230 💬 |