Target Gene/Pathway💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
1 | Alanine, aspartate and glutamate metabolism 💬 5 genes, 3 drugs (DrugBank) and 21 diseases |
CPS1 [1] CPS1 💬 |
D07130 D07130 💬 |
Carglumic acid | 245 [3] 245, 246, 251 💬 |
2 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
3 | Arachidonic acid metabolism 💬 4 genes, 25 drugs (DrugBank) and 38 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
4 | Arginine biosynthesis 💬 1 gene, 1 drug (DrugBank) and 3 diseases |
CPS1 [1] CPS1 💬 |
D07130 D07130 💬 |
Carglumic acid | 245 [3] 245, 246, 251 💬 |
5 | Biosynthesis of amino acids 💬 2 genes, 2 drugs (DrugBank) and 4 diseases |
CPS1 [1] CPS1 💬 |
D07130 D07130 💬 |
Carglumic acid | 245 [3] 245, 246, 251 💬 |
6 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
7 | Carbon metabolism 💬 2 genes, 2 drugs (DrugBank) and 4 diseases |
CPS1 [1] CPS1 💬 |
D07130 D07130 💬 |
Carglumic acid | 245 [3] 245, 246, 251 💬 |
8 | Chemical carcinogenesis 💬 5 genes, 26 drugs (DrugBank) and 37 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
9 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
10 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
11 | IL-17 signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
12 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
13 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
14 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
CPS1 [1] CPS1 💬 |
D07130 D07130 💬 |
Carglumic acid | 245 [3] 245, 246, 251 💬 |
15 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
16 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
17 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00473 D00473 💬 |
Prednisone | 002 [47] 2 , 6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 93, 95, 96, 97, 113, 127, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬 |
18 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
19 | Nitrogen metabolism 💬 14 genes, 5 drugs (DrugBank) and 16 diseases |
CPS1 [1] CPS1 💬 |
D07130 D07130 💬 |
Carglumic acid | 245 [3] 245, 246, 251 💬 |
20 | Ovarian steroidogenesis 💬 6 genes, 34 drugs (DrugBank) and 47 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
21 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
22 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
23 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
24 | Platelet activation 💬 22 genes, 44 drugs (DrugBank) and 47 diseases |
PTGS1 [1] PTGS1 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
25 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
26 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
27 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
28 | Small cell lung cancer 💬 11 genes, 35 drugs (DrugBank) and 51 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
29 | TNF signaling pathway 💬 18 genes, 51 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
30 | VEGF signaling pathway 💬 20 genes, 48 drugs (DrugBank) and 84 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |