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Target Gene/Pathway💬 Info on mouse-over

e.g. Sirolimus, Adalimumab, MAP2K

ABCDEFGH I JKLMNOPQRSTUVWXYZother

94 / 286 pathways

No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related		 KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adherens junction 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
2 Adherens junction 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
3 Adipocytokine signaling pathway 💬
 [1] JAK2 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
4 Adipocytokine signaling pathway 💬
 [1] LEPR 💬 D05014 💬 Metreleptin [1] 265 💬
5 Adipocytokine signaling pathway 💬
 [1] PPARA 💬 D00565 💬 Fenofibrate [5]  8 , 79, 93, 94, 265 💬
6 Adipocytokine signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
7 Adipocytokine signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
8 AGE-RAGE signaling pathway in diabetic complications 💬
 [1] JAK2 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
9 Alcoholism 💬
 [1] ADORA2A 💬 D00528 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
10 Alcoholism 💬
 [1] ADORA2A 💬 D01453 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
11 Aldosterone synthesis and secretion 💬
 [1] PDE2A 💬 D00528 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
12 Aldosterone synthesis and secretion 💬
 [1] PDE2A 💬 D01453 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
13 AMPK signaling pathway 💬
 [1] HMGCR 💬 D00887 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
14 AMPK signaling pathway 💬
 [1] HMGCR 💬 D07474 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
15 AMPK signaling pathway 💬
 [1] HMGCR 💬 D00893 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
16 AMPK signaling pathway 💬
 [1] HMGCR 💬 D08410 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
17 AMPK signaling pathway 💬
 [1] HMGCR 💬 D00434 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
18 AMPK signaling pathway 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
19 AMPK signaling pathway 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
20 AMPK signaling pathway 💬
 [1] LEPR 💬 D05014 💬 Metreleptin [1] 265 💬
21 AMPK signaling pathway 💬
 [1] PPARG 💬 D00945 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
22 AMPK signaling pathway 💬
 [1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
23 AMPK signaling pathway 💬
 [1] PPARG 💬 D00596 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
24 AMPK signaling pathway 💬
 [1] PPARG 💬 D08491 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
25 AMPK signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
26 AMPK signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
27 Apelin signaling pathway 💬
 [1] PDE3B 💬 D00528 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
28 Apelin signaling pathway 💬
 [1] PDE3B 💬 D01453 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
29 Apelin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
30 Apelin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
31 Autophagy - animal 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
32 Autophagy - animal 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
33 Autophagy - animal 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
34 Autophagy - animal 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
35 Bile secretion 💬
 [1] HMGCR 💬 D00887 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
36 Bile secretion 💬
 [1] HMGCR 💬 D07474 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
37 Bile secretion 💬
 [1] HMGCR 💬 D00893 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
38 Bile secretion 💬
 [1] HMGCR 💬 D08410 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
39 Bile secretion 💬
 [1] HMGCR 💬 D00434 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
40 Bile secretion 💬
 [1] NR1H4 💬 D10699 💬 Cholic Acid [4] 20, 234, 265, 310 💬
41 Bile secretion 💬
 [1] NR1H4 💬 D09360 💬 Obeticholic acid [3] 93, 265, 296 💬
42 Breast cancer 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
43 Breast cancer 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
44 Calcium signaling pathway 💬
 [2] ADORA2A, PDE1B 💬 D00528 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
45 Calcium signaling pathway 💬
 [2] ADORA2A, PDE1B 💬 D01453 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
46 cAMP signaling pathway 💬
 [8] ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D00528 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
47 cAMP signaling pathway 💬
 [8] ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D01453 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
48 cAMP signaling pathway 💬
 [1] PPARA 💬 D00565 💬 Fenofibrate [5]  8 , 79, 93, 94, 265 💬
49 cGMP-PKG signaling pathway 💬
 [5] ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 D00528 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
50 cGMP-PKG signaling pathway 💬
 [5] ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 D01453 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
51 Chemokine signaling pathway 💬
 [1] JAK2 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
52 Cholesterol metabolism 💬
 [1] APOC3 💬 D11648 💬 Volanesorsen [1] 265 💬
53 Cholinergic synapse 💬
 [1] JAK2 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
54 Circadian rhythm 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
55 Circadian rhythm 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
56 Coronavirus disease - COVID-19 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
57 Cytokine-cytokine receptor interaction 💬
 [1] GHR 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
58 Cytokine-cytokine receptor interaction 💬
 [1] GHR 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
59 Cytokine-cytokine receptor interaction 💬
 [1] GHR 💬 D02691 💬 Somatotropin [20]  2 ,  3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬
60 Cytokine-cytokine receptor interaction 💬
 [1] LEPR 💬 D05014 💬 Metreleptin [1] 265 💬
61 Diabetic cardiomyopathy 💬
 [1] PPARA 💬 D00565 💬 Fenofibrate [5]  8 , 79, 93, 94, 265 💬
62 EGFR tyrosine kinase inhibitor resistance 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
63 EGFR tyrosine kinase inhibitor resistance 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
64 EGFR tyrosine kinase inhibitor resistance 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
65 Endocrine resistance 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
66 Endocrine resistance 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
67 Endocytosis 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
68 Endocytosis 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
69 Epstein-Barr virus infection 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
70 Fluid shear stress and atherosclerosis 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
71 Fluid shear stress and atherosclerosis 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
72 Focal adhesion 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
73 Focal adhesion 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
74 FoxO signaling pathway 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
75 FoxO signaling pathway 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
76 FoxO signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
77 FoxO signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
78 Glioma 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
79 Glioma 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
80 Glucagon signaling pathway 💬
 [1] PDE3B 💬 D00528 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
81 Glucagon signaling pathway 💬
 [1] PDE3B 💬 D01453 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
82 Glucagon signaling pathway 💬
 [1] PPARA 💬 D00565 💬 Fenofibrate [5]  8 , 79, 93, 94, 265 💬
83 Glucagon signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
84 Glucagon signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
85 Growth hormone synthesis, secretion and action 💬
 [1] GHR 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
86 Growth hormone synthesis, secretion and action 💬
 [1] GHR 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
87 Growth hormone synthesis, secretion and action 💬
 [1] GHR 💬 D02691 💬 Somatotropin [20]  2 ,  3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬
88 Growth hormone synthesis, secretion and action 💬
 [1] GHRHR 💬 D06655 💬 Tesamorelin [2] 78, 265 💬
89 Growth hormone synthesis, secretion and action 💬
 [1] JAK2 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
90 Hepatitis B 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
91 Hepatitis C 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
92 Hepatitis C 💬
 [1] PPARA 💬 D00565 💬 Fenofibrate [5]  8 , 79, 93, 94, 265 💬
93 Hepatocellular carcinoma 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
94 Hepatocellular carcinoma 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
95 Herpes simplex virus 1 infection 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
96 HIF-1 signaling pathway 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
97 HIF-1 signaling pathway 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
98 Human cytomegalovirus infection 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
99 Human papillomavirus infection 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
100 Human T-cell leukemia virus 1 infection 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
101 Huntington disease 💬
 [1] PPARG 💬 D00945 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
102 Huntington disease 💬
 [1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
103 Huntington disease 💬
 [1] PPARG 💬 D00596 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
104 Huntington disease 💬
 [1] PPARG 💬 D08491 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
105 Hypertrophic cardiomyopathy 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
106 Hypertrophic cardiomyopathy 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
107 Influenza A 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
108 Insulin resistance 💬
 [1] PPARA 💬 D00565 💬 Fenofibrate [5]  8 , 79, 93, 94, 265 💬
109 Insulin resistance 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
110 Insulin resistance 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
111 Insulin signaling pathway 💬
 [1] PDE3B 💬 D00528 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
112 Insulin signaling pathway 💬
 [1] PDE3B 💬 D01453 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
113 Insulin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
114 Insulin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
115 JAK-STAT signaling pathway 💬
 [1] GHR 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
116 JAK-STAT signaling pathway 💬
 [1] GHR 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
117 JAK-STAT signaling pathway 💬
 [1] GHR 💬 D02691 💬 Somatotropin [20]  2 ,  3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬
118 JAK-STAT signaling pathway 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
119 JAK-STAT signaling pathway 💬
 [1] LEPR 💬 D05014 💬 Metreleptin [1] 265 💬
120 Kaposi sarcoma-associated herpesvirus infection 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
121 Leishmaniasis 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
122 Long-term depression 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
123 Long-term depression 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
124 Longevity regulating pathway 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
125 Longevity regulating pathway 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
126 Longevity regulating pathway 💬
 [1] PPARG 💬 D00945 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
127 Longevity regulating pathway 💬
 [1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
128 Longevity regulating pathway 💬
 [1] PPARG 💬 D00596 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
129 Longevity regulating pathway 💬
 [1] PPARG 💬 D08491 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
130 Longevity regulating pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
131 Longevity regulating pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
132 Longevity regulating pathway - multiple species 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
133 Longevity regulating pathway - multiple species 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
134 Longevity regulating pathway - multiple species 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
135 Longevity regulating pathway - multiple species 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
136 MAPK signaling pathway 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
137 MAPK signaling pathway 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
138 Measles 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
139 Melanoma 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
140 Melanoma 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
141 Metabolic pathways 💬
 [1] HMGCR 💬 D00887 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
142 Metabolic pathways 💬
 [1] HMGCR 💬 D07474 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
143 Metabolic pathways 💬
 [1] HMGCR 💬 D00893 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
144 Metabolic pathways 💬
 [1] HMGCR 💬 D08410 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
145 Metabolic pathways 💬
 [1] HMGCR 💬 D00434 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
146 Metabolic pathways 💬
 [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 D00528 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
147 Metabolic pathways 💬
 [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 D01453 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
148 Morphine addiction 💬
 [9] ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D00528 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
149 Morphine addiction 💬
 [9] ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D01453 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
150 mTOR signaling pathway 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
151 mTOR signaling pathway 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
152 mTOR signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
153 mTOR signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
154 Necroptosis 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
155 Neuroactive ligand-receptor interaction 💬
 [2] ADORA1, ADORA2A 💬 D00528 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
156 Neuroactive ligand-receptor interaction 💬
 [2] ADORA1, ADORA2A 💬 D01453 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
157 Neuroactive ligand-receptor interaction 💬
 [1] GHR 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
158 Neuroactive ligand-receptor interaction 💬
 [1] GHR 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
159 Neuroactive ligand-receptor interaction 💬
 [1] GHR 💬 D02691 💬 Somatotropin [20]  2 ,  3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬
160 Neuroactive ligand-receptor interaction 💬
 [1] GHRHR 💬 D06655 💬 Tesamorelin [2] 78, 265 💬
161 Neuroactive ligand-receptor interaction 💬
 [1] LEPR 💬 D05014 💬 Metreleptin [1] 265 💬
162 Neuroactive ligand-receptor interaction 💬
 [1] MC4R 💬 D11927 💬 Setmelanotide [2] 202, 265 💬
163 NOD-like receptor signaling pathway 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
164 Non-alcoholic fatty liver disease 💬
 [1] LEPR 💬 D05014 💬 Metreleptin [1] 265 💬
165 Non-alcoholic fatty liver disease 💬
 [1] PPARA 💬 D00565 💬 Fenofibrate [5]  8 , 79, 93, 94, 265 💬
166 Non-alcoholic fatty liver disease 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
167 Non-alcoholic fatty liver disease 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
168 Olfactory transduction 💬
 [2] PDE1B, PDE2A 💬 D00528 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
169 Olfactory transduction 💬
 [2] PDE1B, PDE2A 💬 D01453 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
170 Oocyte meiosis 💬
 [1] AR 💬 D00075 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
171 Oocyte meiosis 💬
 [1] AR 💬 D00957 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
172 Oocyte meiosis 💬
 [1] AR 💬 D00958 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
173 Oocyte meiosis 💬
 [1] AR 💬 D00959 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
174 Oocyte meiosis 💬
 [1] AR 💬 D06085 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
175 Oocyte meiosis 💬
 [1] AR 💬 D06087 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
176 Oocyte meiosis 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
177 Oocyte meiosis 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
178 Osteoclast differentiation 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
179 Osteoclast differentiation 💬
 [1] PPARG 💬 D00945 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
180 Osteoclast differentiation 💬
 [1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
181 Osteoclast differentiation 💬
 [1] PPARG 💬 D00596 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
182 Osteoclast differentiation 💬
 [1] PPARG 💬 D08491 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
183 Ovarian steroidogenesis 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
184 Ovarian steroidogenesis 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
185 Oxytocin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
186 Oxytocin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
187 Pancreatic cancer 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
188 Parathyroid hormone synthesis, secretion and action 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D00528 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
189 Parathyroid hormone synthesis, secretion and action 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D01453 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
190 Parkinson disease 💬
 [1] ADORA2A 💬 D00528 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
191 Parkinson disease 💬
 [1] ADORA2A 💬 D01453 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
192 Pathways in cancer 💬
 [1] AR 💬 D00075 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
193 Pathways in cancer 💬
 [1] AR 💬 D00957 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
194 Pathways in cancer 💬
 [1] AR 💬 D00958 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
195 Pathways in cancer 💬
 [1] AR 💬 D00959 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
196 Pathways in cancer 💬
 [1] AR 💬 D06085 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
197 Pathways in cancer 💬
 [1] AR 💬 D06087 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
198 Pathways in cancer 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
199 Pathways in cancer 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
200 Pathways in cancer 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
201 Pathways in cancer 💬
 [1] PPARG 💬 D00945 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
202 Pathways in cancer 💬
 [1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
203 Pathways in cancer 💬
 [1] PPARG 💬 D00596 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
204 Pathways in cancer 💬
 [1] PPARG 💬 D08491 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
205 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
206 PI3K-Akt signaling pathway 💬
 [1] GHR 💬 D02691 💬 Somatotropin [20]  2 ,  3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬
207 PI3K-Akt signaling pathway 💬
 [2] GHR, IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
208 PI3K-Akt signaling pathway 💬
 [2] GHR, IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
209 PI3K-Akt signaling pathway 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
210 PI3K-Akt signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
211 PI3K-Akt signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
212 PPAR signaling pathway 💬
 [1] APOC3 💬 D11648 💬 Volanesorsen [1] 265 💬
213 PPAR signaling pathway 💬
 [1] PPARA 💬 D00565 💬 Fenofibrate [5]  8 , 79, 93, 94, 265 💬
214 PPAR signaling pathway 💬
 [1] PPARG 💬 D00945 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
215 PPAR signaling pathway 💬
 [1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
216 PPAR signaling pathway 💬
 [1] PPARG 💬 D00596 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
217 PPAR signaling pathway 💬
 [1] PPARG 💬 D08491 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
218 Progesterone-mediated oocyte maturation 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
219 Progesterone-mediated oocyte maturation 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
220 Progesterone-mediated oocyte maturation 💬
 [1] PDE3B 💬 D00528 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
221 Progesterone-mediated oocyte maturation 💬
 [1] PDE3B 💬 D01453 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
222 Prolactin signaling pathway 💬
 [1] JAK2 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
223 Prostate cancer 💬
 [1] AR 💬 D00075 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
224 Prostate cancer 💬
 [1] AR 💬 D00957 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
225 Prostate cancer 💬
 [1] AR 💬 D00958 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
226 Prostate cancer 💬
 [1] AR 💬 D00959 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
227 Prostate cancer 💬
 [1] AR 💬 D06085 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
228 Prostate cancer 💬
 [1] AR 💬 D06087 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
229 Prostate cancer 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
230 Prostate cancer 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
231 Proteoglycans in cancer 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
232 Proteoglycans in cancer 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
233 Purine metabolism 💬
 [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 D00528 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
234 Purine metabolism 💬
 [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 D01453 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
235 Rap1 signaling pathway 💬
 [1] ADORA2A 💬 D00528 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
236 Rap1 signaling pathway 💬
 [1] ADORA2A 💬 D01453 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
237 Rap1 signaling pathway 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
238 Rap1 signaling pathway 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
239 Ras signaling pathway 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
240 Ras signaling pathway 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
241 Regulation of lipolysis in adipocytes 💬
 [2] ADORA1, PDE3B 💬 D00528 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
242 Regulation of lipolysis in adipocytes 💬
 [2] ADORA1, PDE3B 💬 D01453 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
243 Renin secretion 💬
 [4] ADORA1, PDE1B, PDE3A, PDE3B 💬 D00528 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
244 Renin secretion 💬
 [4] ADORA1, PDE1B, PDE3A, PDE3B 💬 D01453 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
245 Signaling pathways regulating pluripotency of stem cells 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
246 Signaling pathways regulating pluripotency of stem cells 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
247 Signaling pathways regulating pluripotency of stem cells 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
248 Sphingolipid signaling pathway 💬
 [1] ADORA1 💬 D00528 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
249 Sphingolipid signaling pathway 💬
 [1] ADORA1 💬 D01453 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
250 Taste transduction 💬
 [1] PDE1B 💬 D00528 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
251 Taste transduction 💬
 [1] PDE1B 💬 D01453 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
252 Terpenoid backbone biosynthesis 💬
 [1] HMGCR 💬 D00887 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
253 Terpenoid backbone biosynthesis 💬
 [1] HMGCR 💬 D07474 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
254 Terpenoid backbone biosynthesis 💬
 [1] HMGCR 💬 D00893 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
255 Terpenoid backbone biosynthesis 💬
 [1] HMGCR 💬 D08410 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
256 Terpenoid backbone biosynthesis 💬
 [1] HMGCR 💬 D00434 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
257 Th1 and Th2 cell differentiation 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
258 Th17 cell differentiation 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
259 Thermogenesis 💬
 [1] PPARG 💬 D00945 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
260 Thermogenesis 💬
 [1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
261 Thermogenesis 💬
 [1] PPARG 💬 D00596 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
262 Thermogenesis 💬
 [1] PPARG 💬 D08491 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
263 Thermogenesis 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
264 Thermogenesis 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
265 Thyroid cancer 💬
 [1] PPARG 💬 D00945 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
266 Thyroid cancer 💬
 [1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
267 Thyroid cancer 💬
 [1] PPARG 💬 D00596 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
268 Thyroid cancer 💬
 [1] PPARG 💬 D08491 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
269 Tight junction 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
270 Tight junction 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
271 Toxoplasmosis 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
272 Transcriptional misregulation in cancer 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
273 Transcriptional misregulation in cancer 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
274 Transcriptional misregulation in cancer 💬
 [1] PPARG 💬 D00945 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
275 Transcriptional misregulation in cancer 💬
 [1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
276 Transcriptional misregulation in cancer 💬
 [1] PPARG 💬 D00596 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
277 Transcriptional misregulation in cancer 💬
 [1] PPARG 💬 D08491 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
278 Tuberculosis 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
279 Vascular smooth muscle contraction 💬
 [1] ADORA2A 💬 D00528 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
280 Vascular smooth muscle contraction 💬
 [1] ADORA2A 💬 D01453 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
281 Viral carcinogenesis 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬

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