Target Gene/Pathway💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
1 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
2 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
3 | Amoebiasis 💬 17 genes, 25 drugs (DrugBank) and 62 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
4 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
5 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
6 | Axon guidance 💬 21 genes, 19 drugs (DrugBank) and 65 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
7 | B cell receptor signaling pathway 💬 16 genes, 19 drugs (DrugBank) and 63 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
8 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
TNFSF11 [1] TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 [7] 46, 50, 93, 95, 96, 274, 299 💬 |
9 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
10 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
11 | Cell cycle 💬 7 genes, 8 drugs (DrugBank) and 23 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
12 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
13 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
14 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
15 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
16 | Chronic myeloid leukemia 💬 14 genes, 15 drugs (DrugBank) and 28 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
17 | Colorectal cancer 💬 14 genes, 19 drugs (DrugBank) and 49 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
18 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [20] 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
19 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
20 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
TNFSF11 [1] TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 [7] 46, 50, 93, 95, 96, 274, 299 💬 |
21 | Diabetic cardiomyopathy 💬 21 genes, 38 drugs (DrugBank) and 72 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
22 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
23 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
PPP3CA [3] PPP3CA, PPP3CB, PPP3CC 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
24 | Endocrine and other factor-regulated calcium reabsorption 💬 7 genes, 25 drugs (DrugBank) and 49 diseases |
PTH1R [1] PTH1R 💬 |
D06078 D06078 💬 |
Teriparatide | 046 [7] 46, 65, 68, 70, 71, 235, 274 💬 |
25 | FoxO signaling pathway 💬 24 genes, 34 drugs (DrugBank) and 53 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
26 | Gastric cancer 💬 20 genes, 29 drugs (DrugBank) and 57 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
27 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
28 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
29 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [20] 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
30 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
MS4A1 [1] MS4A1 💬 |
D02994 D02994 💬 |
Rituximab | 011 [47] 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬 |
31 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
32 | Hepatocellular carcinoma 💬 18 genes, 25 drugs (DrugBank) and 57 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
33 | Hippo signaling pathway 💬 6 genes, 4 drugs (DrugBank) and 8 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
34 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
35 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
36 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
FDPS [1] FDPS 💬 |
D00939 D00939 💬 |
Alendronic acid | 019 [7] 19, 41, 46, 50, 271, 274, 299 💬 |
37 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
FDPS [1] FDPS 💬 |
D07119 D07119 💬 |
Alendronic acid | 019 [7] 19, 41, 46, 50, 271, 274, 299 💬 |
38 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
FDPS [1] FDPS 💬 |
D08056 D08056 💬 |
Ibandronate | 046 [3] 46, 49, 274 💬 |
39 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
FDPS [1] FDPS 💬 |
D00941 D00941 💬 |
Pamidronic acid | 271 [2] 271, 274 💬 |
40 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
FDPS [1] FDPS 💬 |
D07281 D07281 💬 |
Pamidronic acid | 271 [2] 271, 274 💬 |
41 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
FDPS [1] FDPS 💬 |
D00942 D00942 💬 |
Risedronic acid | 046 [8] 46, 50, 66, 93, 95, 96, 113, 274 💬 |
42 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
FDPS [1] FDPS 💬 |
D03234 D03234 💬 |
Risedronic acid | 046 [8] 46, 50, 66, 93, 95, 96, 113, 274 💬 |
43 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
FDPS [1] FDPS 💬 |
D08484 D08484 💬 |
Risedronic acid | 046 [8] 46, 50, 66, 93, 95, 96, 113, 274 💬 |
44 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
FDPS [1] FDPS 💬 |
D01968 D01968 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
45 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
FDPS [1] FDPS 💬 |
D06378 D06378 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
46 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
FDPS [1] FDPS 💬 |
D06379 D06379 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
47 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
FDPS [1] FDPS 💬 |
D08689 D08689 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
48 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
49 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
50 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
51 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
52 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
FDPS [1] FDPS 💬 |
D00939 D00939 💬 |
Alendronic acid | 019 [7] 19, 41, 46, 50, 271, 274, 299 💬 |
53 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
FDPS [1] FDPS 💬 |
D07119 D07119 💬 |
Alendronic acid | 019 [7] 19, 41, 46, 50, 271, 274, 299 💬 |
54 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
FDPS [1] FDPS 💬 |
D08056 D08056 💬 |
Ibandronate | 046 [3] 46, 49, 274 💬 |
55 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
FDPS [1] FDPS 💬 |
D00941 D00941 💬 |
Pamidronic acid | 271 [2] 271, 274 💬 |
56 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
FDPS [1] FDPS 💬 |
D07281 D07281 💬 |
Pamidronic acid | 271 [2] 271, 274 💬 |
57 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
FDPS [1] FDPS 💬 |
D00942 D00942 💬 |
Risedronic acid | 046 [8] 46, 50, 66, 93, 95, 96, 113, 274 💬 |
58 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
FDPS [1] FDPS 💬 |
D03234 D03234 💬 |
Risedronic acid | 046 [8] 46, 50, 66, 93, 95, 96, 113, 274 💬 |
59 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
FDPS [1] FDPS 💬 |
D08484 D08484 💬 |
Risedronic acid | 046 [8] 46, 50, 66, 93, 95, 96, 113, 274 💬 |
60 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
FDPS [1] FDPS 💬 |
D01968 D01968 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
61 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
FDPS [1] FDPS 💬 |
D06378 D06378 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
62 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
FDPS [1] FDPS 💬 |
D06379 D06379 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
63 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
FDPS [1] FDPS 💬 |
D08689 D08689 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
64 | Intestinal immune network for IgA production 💬 27 genes, 23 drugs (DrugBank) and 47 diseases |
TGFB1 [1] TGFB1 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
65 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [20] 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
66 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
67 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
68 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
69 | Malaria 💬 14 genes, 25 drugs (DrugBank) and 62 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
70 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
71 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
72 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
FDPS [1] FDPS 💬 |
D00939 D00939 💬 |
Alendronic acid | 019 [7] 19, 41, 46, 50, 271, 274, 299 💬 |
73 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
FDPS [1] FDPS 💬 |
D07119 D07119 💬 |
Alendronic acid | 019 [7] 19, 41, 46, 50, 271, 274, 299 💬 |
74 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
FDPS [1] FDPS 💬 |
D08056 D08056 💬 |
Ibandronate | 046 [3] 46, 49, 274 💬 |
75 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
FDPS [1] FDPS 💬 |
D00941 D00941 💬 |
Pamidronic acid | 271 [2] 271, 274 💬 |
76 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
FDPS [1] FDPS 💬 |
D07281 D07281 💬 |
Pamidronic acid | 271 [2] 271, 274 💬 |
77 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
FDPS [1] FDPS 💬 |
D00942 D00942 💬 |
Risedronic acid | 046 [8] 46, 50, 66, 93, 95, 96, 113, 274 💬 |
78 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
FDPS [1] FDPS 💬 |
D03234 D03234 💬 |
Risedronic acid | 046 [8] 46, 50, 66, 93, 95, 96, 113, 274 💬 |
79 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
FDPS [1] FDPS 💬 |
D08484 D08484 💬 |
Risedronic acid | 046 [8] 46, 50, 66, 93, 95, 96, 113, 274 💬 |
80 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
FDPS [1] FDPS 💬 |
D01968 D01968 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
81 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
FDPS [1] FDPS 💬 |
D06378 D06378 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
82 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
FDPS [1] FDPS 💬 |
D06379 D06379 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
83 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
FDPS [1] FDPS 💬 |
D08689 D08689 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
84 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
TGFB2 [1] TGFB2 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
85 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
86 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [20] 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
87 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
PTH1R [1] PTH1R 💬 |
D06078 D06078 💬 |
Teriparatide | 046 [7] 46, 65, 68, 70, 71, 235, 274 💬 |
88 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
TNFSF11 [1] TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 [7] 46, 50, 93, 95, 96, 274, 299 💬 |
89 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
TGFB1 [1] TGFB1 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
90 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
91 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
92 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
TGFB1 [2] TGFB1, TGFB2 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
93 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
TNFSF11 [1] TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 [7] 46, 50, 93, 95, 96, 274, 299 💬 |
94 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
95 | Pancreatic cancer 💬 16 genes, 29 drugs (DrugBank) and 64 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
96 | Parathyroid hormone synthesis, secretion and action 💬 19 genes, 40 drugs (DrugBank) and 58 diseases |
PTH1R [1] PTH1R 💬 |
D06078 D06078 💬 |
Teriparatide | 046 [7] 46, 65, 68, 70, 71, 235, 274 💬 |
97 | Parathyroid hormone synthesis, secretion and action 💬 19 genes, 40 drugs (DrugBank) and 58 diseases |
SOST [1] SOST 💬 |
D10156 D10156 💬 |
Romosozumab | 046 [2] 46, 274 💬 |
98 | Parathyroid hormone synthesis, secretion and action 💬 19 genes, 40 drugs (DrugBank) and 58 diseases |
TNFSF11 [1] TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 [7] 46, 50, 93, 95, 96, 274, 299 💬 |
99 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
100 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
101 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
102 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [20] 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
103 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
104 | Prolactin signaling pathway 💬 18 genes, 33 drugs (DrugBank) and 48 diseases |
TNFSF11 [1] TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 [7] 46, 50, 93, 95, 96, 274, 299 💬 |
105 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
TGFB1 [2] TGFB1, TGFB2 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
106 | Relaxin signaling pathway 💬 18 genes, 25 drugs (DrugBank) and 38 diseases |
TGFB1 [1] TGFB1 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
107 | Renal cell carcinoma 💬 12 genes, 12 drugs (DrugBank) and 21 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
108 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
109 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
110 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
TNFSF11 [1] TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 [7] 46, 50, 93, 95, 96, 274, 299 💬 |
111 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
112 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
FDPS [1] FDPS 💬 |
D00939 D00939 💬 |
Alendronic acid | 019 [7] 19, 41, 46, 50, 271, 274, 299 💬 |
113 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
FDPS [1] FDPS 💬 |
D07119 D07119 💬 |
Alendronic acid | 019 [7] 19, 41, 46, 50, 271, 274, 299 💬 |
114 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
FDPS [1] FDPS 💬 |
D08056 D08056 💬 |
Ibandronate | 046 [3] 46, 49, 274 💬 |
115 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
FDPS [1] FDPS 💬 |
D00941 D00941 💬 |
Pamidronic acid | 271 [2] 271, 274 💬 |
116 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
FDPS [1] FDPS 💬 |
D07281 D07281 💬 |
Pamidronic acid | 271 [2] 271, 274 💬 |
117 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
FDPS [1] FDPS 💬 |
D00942 D00942 💬 |
Risedronic acid | 046 [8] 46, 50, 66, 93, 95, 96, 113, 274 💬 |
118 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
FDPS [1] FDPS 💬 |
D03234 D03234 💬 |
Risedronic acid | 046 [8] 46, 50, 66, 93, 95, 96, 113, 274 💬 |
119 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
FDPS [1] FDPS 💬 |
D08484 D08484 💬 |
Risedronic acid | 046 [8] 46, 50, 66, 93, 95, 96, 113, 274 💬 |
120 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
FDPS [1] FDPS 💬 |
D01968 D01968 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
121 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
FDPS [1] FDPS 💬 |
D06378 D06378 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
122 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
FDPS [1] FDPS 💬 |
D06379 D06379 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
123 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
FDPS [1] FDPS 💬 |
D08689 D08689 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
124 | TGF-beta signaling pathway 💬 11 genes, 20 drugs (DrugBank) and 54 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
125 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
126 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
127 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
TGFB1 [1] TGFB1 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
128 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
129 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
130 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
131 | VEGF signaling pathway 💬 20 genes, 48 drugs (DrugBank) and 84 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
132 | Wnt signaling pathway 💬 8 genes, 7 drugs (DrugBank) and 56 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
133 | Wnt signaling pathway 💬 8 genes, 7 drugs (DrugBank) and 56 diseases |
SOST [1] SOST 💬 |
D10156 D10156 💬 |
Romosozumab | 046 [2] 46, 274 💬 |