Target Gene/Pathway💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
1 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PDE3B [1] PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 [1] 294 💬 |
2 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PDE3B [1] PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 [1] 294 💬 |
3 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 [1] 294 💬 |
4 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 [1] 294 💬 |
5 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 [1] 294 💬 |
6 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 [1] 294 💬 |
7 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PDE5A [1] PDE5A 💬 |
D02229 D02229 💬 |
Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
8 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PDE5A [1] PDE5A 💬 |
D08514 D08514 💬 |
Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
9 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
10 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D01207 D01207 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
11 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D05259 D05259 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
12 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D05261 D05261 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
13 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
14 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D01207 D01207 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
15 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D05259 D05259 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
16 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D05261 D05261 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
17 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PDE3B [1] PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 [1] 294 💬 |
18 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PDE3B [1] PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 [1] 294 💬 |
19 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
PDE3B [1] PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 [1] 294 💬 |
20 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
PDE3B [1] PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 [1] 294 💬 |
21 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
22 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D01207 D01207 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
23 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D05259 D05259 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
24 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D05261 D05261 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
25 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 [1] 294 💬 |
26 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 [1] 294 💬 |
27 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PDE5A [1] PDE5A 💬 |
D02229 D02229 💬 |
Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
28 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PDE5A [1] PDE5A 💬 |
D08514 D08514 💬 |
Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
29 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 [1] 294 💬 |
30 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 [1] 294 💬 |
31 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 23 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
32 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 23 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D01207 D01207 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
33 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 23 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D05259 D05259 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
34 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 23 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D05261 D05261 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
35 | Progesterone-mediated oocyte maturation 💬 14 genes, 32 drugs (DrugBank) and 37 diseases |
PDE3B [1] PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 [1] 294 💬 |
36 | Progesterone-mediated oocyte maturation 💬 14 genes, 32 drugs (DrugBank) and 37 diseases |
PDE3B [1] PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 [1] 294 💬 |
37 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 [1] 294 💬 |
38 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 [1] 294 💬 |
39 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
PDE5A [1] PDE5A 💬 |
D02229 D02229 💬 |
Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
40 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
PDE5A [1] PDE5A 💬 |
D08514 D08514 💬 |
Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
41 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
PDE3B [1] PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 [1] 294 💬 |
42 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
PDE3B [1] PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 [1] 294 💬 |
43 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 [1] 294 💬 |
44 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 [1] 294 💬 |