DDrare: Database of Drug Development for Rare Diseases

Target Gene/Pathway💬 Info on mouse-over

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174 / 286 pathways

No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Acute myeloid leukemia 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
2	Acute myeloid leukemia 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
3	Acute myeloid leukemia 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
4	Acute myeloid leukemia 💬	[1] RARA 💬	D06543 💬	Vitamin A	[3] 13, 53, 90 💬
5	Adipocytokine signaling pathway 💬	[1] JAK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
6	Adipocytokine signaling pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
7	Adipocytokine signaling pathway 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
8	Adipocytokine signaling pathway 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
9	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬	D01450 💬	Bupivacaine	[8] 46, 51, 53, 70, 96, 168, 226, 298 💬
10	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬	D07552 💬	Bupivacaine	[8] 46, 51, 53, 70, 96, 168, 226, 298 💬
11	African trypanosomiasis 💬	[2] IL12A, IL12B 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
12	African trypanosomiasis 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
13	African trypanosomiasis 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
14	AGE-RAGE signaling pathway in diabetic complications 💬	[1] JAK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
15	AGE-RAGE signaling pathway in diabetic complications 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
16	AGE-RAGE signaling pathway in diabetic complications 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
17	AGE-RAGE signaling pathway in diabetic complications 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
18	AGE-RAGE signaling pathway in diabetic complications 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
19	AGE-RAGE signaling pathway in diabetic complications 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
20	Aldosterone-regulated sodium reabsorption 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
21	Aldosterone-regulated sodium reabsorption 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
22	Allograft rejection 💬	[1] CD40 💬	D11610 💬	Iscalimab	[2] 49, 53 💬
23	Allograft rejection 💬	[2] CD80, CD86 💬	D03203 💬	Abatacept	[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
24	Allograft rejection 💬	[2] IL12A, IL12B 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
25	Allograft rejection 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
26	Allograft rejection 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
27	Alzheimer disease 💬	[1] CHRM3 💬	D00661 💬	Cevimeline	[1] 53 💬
28	Alzheimer disease 💬	[1] CHRM3 💬	D07667 💬	Cevimeline	[1] 53 💬
29	Alzheimer disease 💬	[1] CHRM3 💬	D00525 💬	Pilocarpine	[3] 6 , 53, 299 💬
30	Alzheimer disease 💬	[1] CHRM3 💬	D02200 💬	Pilocarpine	[3] 6 , 53, 299 💬
31	Alzheimer disease 💬	[1] CHRM3 💬	D05478 💬	Pilocarpine	[3] 6 , 53, 299 💬
32	Alzheimer disease 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
33	Alzheimer disease 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
34	Alzheimer disease 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
35	Alzheimer disease 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
36	Alzheimer disease 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
37	Alzheimer disease 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
38	Alzheimer disease 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
39	Alzheimer disease 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
40	Amoebiasis 💬	[2] IL12A, IL12B 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
41	Amoebiasis 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
42	Amoebiasis 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
43	Amoebiasis 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
44	Amoebiasis 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
45	Amoebiasis 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
46	Amphetamine addiction 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
47	Amphetamine addiction 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
48	Amphetamine addiction 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
49	AMPK signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
50	AMPK signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
51	Amyotrophic lateral sclerosis 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
52	Amyotrophic lateral sclerosis 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
53	Amyotrophic lateral sclerosis 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
54	Amyotrophic lateral sclerosis 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
55	Amyotrophic lateral sclerosis 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
56	Antifolate resistance 💬	[2] DHFR, DHFR2 💬	D00142 💬	Methotrexate	[35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
57	Antifolate resistance 💬	[2] DHFR, DHFR2 💬	D02115 💬	Methotrexate	[35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
58	Antifolate resistance 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
59	Antifolate resistance 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
60	Antifolate resistance 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
61	Antigen processing and presentation 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
62	Antigen processing and presentation 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
63	Apoptosis 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
64	Apoptosis 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
65	Apoptosis 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
66	Apoptosis 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
67	Apoptosis 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
68	Asthma 💬	[1] CD40 💬	D11610 💬	Iscalimab	[2] 49, 53 💬
69	Asthma 💬	[1] FCER1A 💬	D05251 💬	Omalizumab	[7] 46, 53, 65, 98, 162, 226, 299 💬
70	Asthma 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
71	Asthma 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
72	Autoimmune thyroid disease 💬	[1] CD40 💬	D11610 💬	Iscalimab	[2] 49, 53 💬
73	Autoimmune thyroid disease 💬	[2] CD80, CD86 💬	D03203 💬	Abatacept	[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
74	Autophagy - animal 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
75	Autophagy - animal 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
76	Axon guidance 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
77	Axon guidance 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
78	Axon guidance 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
79	Axon guidance 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
80	Axon guidance 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
81	B cell receptor signaling pathway 💬	[1] BTK 💬	D11478 💬	Branebrutinib	[3] 46, 49, 53 💬
82	B cell receptor signaling pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
83	B cell receptor signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
84	B cell receptor signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
85	B cell receptor signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
86	B cell receptor signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
87	B cell receptor signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
88	Bacterial invasion of epithelial cells 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
89	Bacterial invasion of epithelial cells 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
90	Biosynthesis of cofactors 💬	[2] DHFR, DHFR2 💬	D00142 💬	Methotrexate	[35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
91	Biosynthesis of cofactors 💬	[2] DHFR, DHFR2 💬	D02115 💬	Methotrexate	[35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
92	Biosynthesis of cofactors 💬	[1] DHODH 💬	D00749 💬	Leflunomide	[10] 11, 40, 46, 49, 53, 66, 162, 224, 271, 300 💬
93	Breast cancer 💬	[2] ESR1, ESR2 💬	D11513 💬	Estetrol	[1] 53 💬
94	Breast cancer 💬	[2] ESR1, ESR2 💬	D11514 💬	Estetrol	[1] 53 💬
95	Breast cancer 💬	[2] ESR1, ESR2 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
96	Breast cancer 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
97	Breast cancer 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
98	C-type lectin receptor signaling pathway 💬	[3] IL12A, IL12B, IL23A 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
99	C-type lectin receptor signaling pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
100	C-type lectin receptor signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
101	C-type lectin receptor signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
102	C-type lectin receptor signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
103	C-type lectin receptor signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
104	C-type lectin receptor signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
105	C-type lectin receptor signaling pathway 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
106	C-type lectin receptor signaling pathway 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
107	Calcium signaling pathway 💬	[2] CHRM2, CHRM3 💬	D00525 💬	Pilocarpine	[3] 6 , 53, 299 💬
108	Calcium signaling pathway 💬	[2] CHRM2, CHRM3 💬	D02200 💬	Pilocarpine	[3] 6 , 53, 299 💬
109	Calcium signaling pathway 💬	[2] CHRM2, CHRM3 💬	D05478 💬	Pilocarpine	[3] 6 , 53, 299 💬
110	Calcium signaling pathway 💬	[1] CHRM3 💬	D00661 💬	Cevimeline	[1] 53 💬
111	Calcium signaling pathway 💬	[1] CHRM3 💬	D07667 💬	Cevimeline	[1] 53 💬
112	Calcium signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
113	Calcium signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
114	Calcium signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
115	cAMP signaling pathway 💬	[1] CHRM2 💬	D00525 💬	Pilocarpine	[3] 6 , 53, 299 💬
116	cAMP signaling pathway 💬	[1] CHRM2 💬	D02200 💬	Pilocarpine	[3] 6 , 53, 299 💬
117	cAMP signaling pathway 💬	[1] CHRM2 💬	D05478 💬	Pilocarpine	[3] 6 , 53, 299 💬
118	cAMP signaling pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
119	cAMP signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
120	cAMP signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
121	Carbohydrate digestion and absorption 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
122	Carbohydrate digestion and absorption 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
123	Cell adhesion molecules 💬	[1] CD40 💬	D11610 💬	Iscalimab	[2] 49, 53 💬
124	Cell adhesion molecules 💬	[2] CD80, CD86 💬	D03203 💬	Abatacept	[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
125	Cell adhesion molecules 💬	[1] ITGAL 💬	D03959 💬	Efalizumab	[9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
126	Cell adhesion molecules 💬	[1] PDCD1 💬	D10316 💬	Nivolumab	[12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
127	Cellular senescence 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
128	Cellular senescence 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
129	Cellular senescence 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
130	Cellular senescence 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
131	Cellular senescence 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
132	Cellular senescence 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
133	Central carbon metabolism in cancer 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
134	Central carbon metabolism in cancer 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
135	cGMP-PKG signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
136	cGMP-PKG signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
137	cGMP-PKG signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
138	Chagas disease 💬	[2] IL12A, IL12B 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
139	Chagas disease 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
140	Chagas disease 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
141	Chagas disease 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
142	Chagas disease 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
143	Chagas disease 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
144	Chemokine signaling pathway 💬	[2] JAK2, JAK3 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
145	Chemokine signaling pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
146	Chemokine signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
147	Chemokine signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
148	Choline metabolism in cancer 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
149	Choline metabolism in cancer 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
150	Cholinergic synapse 💬	[2] CHRM2, CHRM3 💬	D00525 💬	Pilocarpine	[3] 6 , 53, 299 💬
151	Cholinergic synapse 💬	[2] CHRM2, CHRM3 💬	D02200 💬	Pilocarpine	[3] 6 , 53, 299 💬
152	Cholinergic synapse 💬	[2] CHRM2, CHRM3 💬	D05478 💬	Pilocarpine	[3] 6 , 53, 299 💬
153	Cholinergic synapse 💬	[1] CHRM3 💬	D00661 💬	Cevimeline	[1] 53 💬
154	Cholinergic synapse 💬	[1] CHRM3 💬	D07667 💬	Cevimeline	[1] 53 💬
155	Cholinergic synapse 💬	[1] JAK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
156	Cholinergic synapse 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
157	Cholinergic synapse 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
158	Chronic myeloid leukemia 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
159	Chronic myeloid leukemia 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
160	Chronic myeloid leukemia 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
161	Cocaine addiction 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
162	Colorectal cancer 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
163	Colorectal cancer 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
164	Coronavirus disease - COVID-19 💬	[2] IL12A, IL12B 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
165	Coronavirus disease - COVID-19 💬	[1] IL6R 💬	D02596 💬	Tocilizumab	[18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
166	Coronavirus disease - COVID-19 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
167	Coronavirus disease - COVID-19 💬	[2] JAK1, TYK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
168	Coronavirus disease - COVID-19 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
169	Coronavirus disease - COVID-19 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
170	Coronavirus disease - COVID-19 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
171	Coronavirus disease - COVID-19 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
172	Coronavirus disease - COVID-19 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
173	Cytokine-cytokine receptor interaction 💬	[1] CD40 💬	D11610 💬	Iscalimab	[2] 49, 53 💬
174	Cytokine-cytokine receptor interaction 💬	[3] IL12A, IL12B, IL23A 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
175	Cytokine-cytokine receptor interaction 💬	[2] IL17A, TNFSF13B 💬	D11127 💬	Tibulizumab	[1] 53 💬
176	Cytokine-cytokine receptor interaction 💬	[1] IL6R 💬	D02596 💬	Tocilizumab	[18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
177	Cytokine-cytokine receptor interaction 💬	[2] LTA, TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
178	Cytokine-cytokine receptor interaction 💬	[1] LTB 💬	D08866 💬	Baminercept	[4] 13, 46, 53, 97 💬
179	Cytokine-cytokine receptor interaction 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
180	Cytokine-cytokine receptor interaction 💬	[1] TNFSF13B 💬	D03068 💬	Belimumab	[10] 11, 43, 44, 46, 49, 51, 53, 66, 222, 300 💬
181	Cytosolic DNA-sensing pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
182	Diabetic cardiomyopathy 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
183	Diabetic cardiomyopathy 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
184	Diabetic cardiomyopathy 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
185	Dilated cardiomyopathy 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
186	Dilated cardiomyopathy 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
187	Dopaminergic synapse 💬	[3] PPP3CA, PPP3CB, PPP3CC 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
188	Dopaminergic synapse 💬	[3] PPP3CA, PPP3CB, PPP3CC 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
189	Dopaminergic synapse 💬	[3] PPP3CA, PPP3CB, PPP3CC 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
190	Dopaminergic synapse 💬	[1] SCN1A 💬	D01450 💬	Bupivacaine	[8] 46, 51, 53, 70, 96, 168, 226, 298 💬
191	Dopaminergic synapse 💬	[1] SCN1A 💬	D07552 💬	Bupivacaine	[8] 46, 51, 53, 70, 96, 168, 226, 298 💬
192	Drug metabolism - other enzymes 💬	[2] IMPDH1, IMPDH2 💬	D01392 💬	Mizoribine	[8] 46, 49, 51, 53, 66, 94, 222, 224 💬
193	Drug metabolism - other enzymes 💬	[2] IMPDH1, IMPDH2 💬	D00752 💬	Mycophenolate mofetil	[32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
194	Drug metabolism - other enzymes 💬	[2] IMPDH1, IMPDH2 💬	D05094 💬	Mycophenolate mofetil	[32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
195	Drug metabolism - other enzymes 💬	[2] IMPDH1, IMPDH2 💬	D05095 💬	Mycophenolate mofetil	[32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
196	Drug metabolism - other enzymes 💬	[2] IMPDH1, IMPDH2 💬	D05096 💬	Mycophenolic acid	[34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
197	EGFR tyrosine kinase inhibitor resistance 💬	[1] IL6R 💬	D02596 💬	Tocilizumab	[18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
198	EGFR tyrosine kinase inhibitor resistance 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
199	EGFR tyrosine kinase inhibitor resistance 💬	[2] JAK1, JAK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
200	EGFR tyrosine kinase inhibitor resistance 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
201	EGFR tyrosine kinase inhibitor resistance 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
202	Endocrine and other factor-regulated calcium reabsorption 💬	[1] ESR1 💬	D11513 💬	Estetrol	[1] 53 💬
203	Endocrine and other factor-regulated calcium reabsorption 💬	[1] ESR1 💬	D11514 💬	Estetrol	[1] 53 💬
204	Endocrine and other factor-regulated calcium reabsorption 💬	[1] ESR1 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
205	Endocrine and other factor-regulated calcium reabsorption 💬	[1] VDR 💬	D00188 💬	Cholecalciferol	[23] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 162, 202, 228, 271, 298, 299 💬
206	Endocrine resistance 💬	[2] ESR1, ESR2 💬	D11513 💬	Estetrol	[1] 53 💬
207	Endocrine resistance 💬	[2] ESR1, ESR2 💬	D11514 💬	Estetrol	[1] 53 💬
208	Endocrine resistance 💬	[2] ESR1, ESR2 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
209	Endocrine resistance 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
210	Endocrine resistance 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
211	Endometrial cancer 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
212	Endometrial cancer 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
213	Epithelial cell signaling in Helicobacter pylori infection 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
214	Epstein-Barr virus infection 💬	[1] BTK 💬	D11478 💬	Branebrutinib	[3] 46, 49, 53 💬
215	Epstein-Barr virus infection 💬	[1] CD40 💬	D11610 💬	Iscalimab	[2] 49, 53 💬
216	Epstein-Barr virus infection 💬	[1] ITGAL 💬	D03959 💬	Efalizumab	[9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
217	Epstein-Barr virus infection 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
218	Epstein-Barr virus infection 💬	[3] JAK1, JAK3, TYK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
219	Epstein-Barr virus infection 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
220	Epstein-Barr virus infection 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
221	Epstein-Barr virus infection 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
222	Epstein-Barr virus infection 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
223	Epstein-Barr virus infection 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
224	ErbB signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
225	ErbB signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
226	Estrogen signaling pathway 💬	[2] ESR1, ESR2 💬	D11513 💬	Estetrol	[1] 53 💬
227	Estrogen signaling pathway 💬	[2] ESR1, ESR2 💬	D11514 💬	Estetrol	[1] 53 💬
228	Estrogen signaling pathway 💬	[2] ESR1, ESR2 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
229	Estrogen signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
230	Estrogen signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
231	Estrogen signaling pathway 💬	[1] RARA 💬	D06543 💬	Vitamin A	[3] 13, 53, 90 💬
232	Fc epsilon RI signaling pathway 💬	[1] BTK 💬	D11478 💬	Branebrutinib	[3] 46, 49, 53 💬
233	Fc epsilon RI signaling pathway 💬	[1] FCER1A 💬	D05251 💬	Omalizumab	[7] 46, 53, 65, 98, 162, 226, 299 💬
234	Fc epsilon RI signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
235	Fc epsilon RI signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
236	Fc epsilon RI signaling pathway 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
237	Fc epsilon RI signaling pathway 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
238	Fc gamma R-mediated phagocytosis 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
239	Fc gamma R-mediated phagocytosis 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
240	Fluid shear stress and atherosclerosis 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
241	Fluid shear stress and atherosclerosis 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
242	Fluid shear stress and atherosclerosis 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
243	Fluid shear stress and atherosclerosis 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
244	Fluid shear stress and atherosclerosis 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
245	Focal adhesion 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
246	Focal adhesion 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
247	Folate biosynthesis 💬	[2] DHFR, DHFR2 💬	D00142 💬	Methotrexate	[35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
248	Folate biosynthesis 💬	[2] DHFR, DHFR2 💬	D02115 💬	Methotrexate	[35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
249	FoxO signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
250	FoxO signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
251	Gastric acid secretion 💬	[1] CHRM3 💬	D00661 💬	Cevimeline	[1] 53 💬
252	Gastric acid secretion 💬	[1] CHRM3 💬	D07667 💬	Cevimeline	[1] 53 💬
253	Gastric acid secretion 💬	[1] CHRM3 💬	D00525 💬	Pilocarpine	[3] 6 , 53, 299 💬
254	Gastric acid secretion 💬	[1] CHRM3 💬	D02200 💬	Pilocarpine	[3] 6 , 53, 299 💬
255	Gastric acid secretion 💬	[1] CHRM3 💬	D05478 💬	Pilocarpine	[3] 6 , 53, 299 💬
256	Gastric cancer 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
257	Gastric cancer 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
258	Gastric cancer 💬	[1] RARB 💬	D06543 💬	Vitamin A	[3] 13, 53, 90 💬
259	Glioma 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
260	Glioma 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
261	Glucagon signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
262	Glucagon signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
263	Glucagon signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
264	Glutamatergic synapse 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
265	Glutamatergic synapse 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
266	Glutamatergic synapse 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
267	GnRH secretion 💬	[1] ESR2 💬	D11513 💬	Estetrol	[1] 53 💬
268	GnRH secretion 💬	[1] ESR2 💬	D11514 💬	Estetrol	[1] 53 💬
269	GnRH secretion 💬	[1] ESR2 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
270	GnRH secretion 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
271	GnRH secretion 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
272	Graft-versus-host disease 💬	[2] CD80, CD86 💬	D03203 💬	Abatacept	[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
273	Graft-versus-host disease 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
274	Graft-versus-host disease 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
275	Growth hormone synthesis, secretion and action 💬	[1] JAK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
276	Growth hormone synthesis, secretion and action 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
277	Growth hormone synthesis, secretion and action 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
278	Hematopoietic cell lineage 💬	[1] IL6R 💬	D02596 💬	Tocilizumab	[18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
279	Hematopoietic cell lineage 💬	[1] MS4A1 💬	D02994 💬	Rituximab	[47] 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
280	Hematopoietic cell lineage 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
281	Hematopoietic cell lineage 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
282	Hepatitis B 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
283	Hepatitis B 💬	[4] JAK1, JAK2, JAK3, TYK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
284	Hepatitis B 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
285	Hepatitis B 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
286	Hepatitis B 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
287	Hepatitis B 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
288	Hepatitis B 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
289	Hepatitis C 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
290	Hepatitis C 💬	[2] JAK1, TYK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
291	Hepatitis C 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
292	Hepatitis C 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
293	Hepatitis C 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
294	Hepatitis C 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
295	Hepatitis C 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
296	Hepatocellular carcinoma 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
297	Hepatocellular carcinoma 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
298	Herpes simplex virus 1 infection 💬	[2] IL12A, IL12B 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
299	Herpes simplex virus 1 infection 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
300	Herpes simplex virus 1 infection 💬	[3] JAK1, JAK2, TYK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
301	Herpes simplex virus 1 infection 💬	[2] LTA, TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
302	Herpes simplex virus 1 infection 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
303	Herpes simplex virus 1 infection 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
304	Herpes simplex virus 1 infection 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
305	Herpes simplex virus 1 infection 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
306	HIF-1 signaling pathway 💬	[1] IL6R 💬	D02596 💬	Tocilizumab	[18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
307	HIF-1 signaling pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
308	HIF-1 signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
309	HIF-1 signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
310	Human cytomegalovirus infection 💬	[1] IL6R 💬	D02596 💬	Tocilizumab	[18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
311	Human cytomegalovirus infection 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
312	Human cytomegalovirus infection 💬	[1] JAK1 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
313	Human cytomegalovirus infection 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
314	Human cytomegalovirus infection 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
315	Human cytomegalovirus infection 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
316	Human cytomegalovirus infection 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
317	Human cytomegalovirus infection 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
318	Human cytomegalovirus infection 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
319	Human cytomegalovirus infection 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
320	Human cytomegalovirus infection 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
321	Human immunodeficiency virus 1 infection 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
322	Human immunodeficiency virus 1 infection 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
323	Human immunodeficiency virus 1 infection 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
324	Human immunodeficiency virus 1 infection 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
325	Human immunodeficiency virus 1 infection 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
326	Human immunodeficiency virus 1 infection 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
327	Human immunodeficiency virus 1 infection 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
328	Human immunodeficiency virus 1 infection 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
329	Human papillomavirus infection 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
330	Human papillomavirus infection 💬	[2] JAK1, TYK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
331	Human papillomavirus infection 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
332	Human papillomavirus infection 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
333	Human papillomavirus infection 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
334	Human papillomavirus infection 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
335	Human papillomavirus infection 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
336	Human T-cell leukemia virus 1 infection 💬	[1] CD40 💬	D11610 💬	Iscalimab	[2] 49, 53 💬
337	Human T-cell leukemia virus 1 infection 💬	[1] ITGAL 💬	D03959 💬	Efalizumab	[9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
338	Human T-cell leukemia virus 1 infection 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
339	Human T-cell leukemia virus 1 infection 💬	[2] JAK1, JAK3 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
340	Human T-cell leukemia virus 1 infection 💬	[2] LTA, TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
341	Human T-cell leukemia virus 1 infection 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
342	Human T-cell leukemia virus 1 infection 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
343	Human T-cell leukemia virus 1 infection 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
344	Human T-cell leukemia virus 1 infection 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
345	Human T-cell leukemia virus 1 infection 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
346	Human T-cell leukemia virus 1 infection 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
347	Human T-cell leukemia virus 1 infection 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
348	Hypertrophic cardiomyopathy 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
349	Hypertrophic cardiomyopathy 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
350	IL-17 signaling pathway 💬	[1] IL17A 💬	D11127 💬	Tibulizumab	[1] 53 💬
351	IL-17 signaling pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
352	IL-17 signaling pathway 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
353	IL-17 signaling pathway 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
354	Inflammatory bowel disease 💬	[3] IL12A, IL12B, IL23A 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
355	Inflammatory bowel disease 💬	[1] IL17A 💬	D11127 💬	Tibulizumab	[1] 53 💬
356	Inflammatory bowel disease 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
357	Inflammatory bowel disease 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
358	Inflammatory bowel disease 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
359	Inflammatory mediator regulation of TRP channels 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
360	Inflammatory mediator regulation of TRP channels 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
361	Influenza A 💬	[2] IL12A, IL12B 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
362	Influenza A 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
363	Influenza A 💬	[3] JAK1, JAK2, TYK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
364	Influenza A 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
365	Influenza A 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
366	Influenza A 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
367	Influenza A 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
368	Influenza A 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
369	Inositol phosphate metabolism 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
370	Inositol phosphate metabolism 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
371	Insulin resistance 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
372	Insulin resistance 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
373	Insulin resistance 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
374	Insulin resistance 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
375	Insulin resistance 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
376	Insulin secretion 💬	[1] CHRM3 💬	D00661 💬	Cevimeline	[1] 53 💬
377	Insulin secretion 💬	[1] CHRM3 💬	D07667 💬	Cevimeline	[1] 53 💬
378	Insulin secretion 💬	[1] CHRM3 💬	D00525 💬	Pilocarpine	[3] 6 , 53, 299 💬
379	Insulin secretion 💬	[1] CHRM3 💬	D02200 💬	Pilocarpine	[3] 6 , 53, 299 💬
380	Insulin secretion 💬	[1] CHRM3 💬	D05478 💬	Pilocarpine	[3] 6 , 53, 299 💬
381	Insulin signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
382	Insulin signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
383	Intestinal immune network for IgA production 💬	[1] CD40 💬	D11610 💬	Iscalimab	[2] 49, 53 💬
384	Intestinal immune network for IgA production 💬	[2] CD80, CD86 💬	D03203 💬	Abatacept	[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
385	Intestinal immune network for IgA production 💬	[1] TNFSF13B 💬	D03068 💬	Belimumab	[10] 11, 43, 44, 46, 49, 51, 53, 66, 222, 300 💬
386	Intestinal immune network for IgA production 💬	[1] TNFSF13B 💬	D11127 💬	Tibulizumab	[1] 53 💬
387	JAK-STAT signaling pathway 💬	[3] IL12A, IL12B, IL23A 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
388	JAK-STAT signaling pathway 💬	[1] IL6R 💬	D02596 💬	Tocilizumab	[18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
389	JAK-STAT signaling pathway 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
390	JAK-STAT signaling pathway 💬	[4] JAK1, JAK2, JAK3, TYK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
391	JAK-STAT signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
392	JAK-STAT signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
393	Kaposi sarcoma-associated herpesvirus infection 💬	[1] CD86 💬	D03203 💬	Abatacept	[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
394	Kaposi sarcoma-associated herpesvirus infection 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
395	Kaposi sarcoma-associated herpesvirus infection 💬	[3] JAK1, JAK2, TYK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
396	Kaposi sarcoma-associated herpesvirus infection 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
397	Kaposi sarcoma-associated herpesvirus infection 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
398	Kaposi sarcoma-associated herpesvirus infection 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
399	Kaposi sarcoma-associated herpesvirus infection 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
400	Kaposi sarcoma-associated herpesvirus infection 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
401	Kaposi sarcoma-associated herpesvirus infection 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
402	Legionellosis 💬	[2] IL12A, IL12B 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
403	Legionellosis 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
404	Legionellosis 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
405	Legionellosis 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
406	Leishmaniasis 💬	[2] IL12A, IL12B 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
407	Leishmaniasis 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
408	Leishmaniasis 💬	[2] JAK1, JAK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
409	Leishmaniasis 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
410	Leishmaniasis 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
411	Leishmaniasis 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
412	Leukocyte transendothelial migration 💬	[1] ITGAL 💬	D03959 💬	Efalizumab	[9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
413	Leukocyte transendothelial migration 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
414	Leukocyte transendothelial migration 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
415	Long-term potentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
416	Long-term potentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
417	Long-term potentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
418	Longevity regulating pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
419	Longevity regulating pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
420	Longevity regulating pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
421	Longevity regulating pathway - multiple species 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
422	Longevity regulating pathway - multiple species 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
423	Malaria 💬	[1] CD40 💬	D11610 💬	Iscalimab	[2] 49, 53 💬
424	Malaria 💬	[1] IL12A 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
425	Malaria 💬	[1] ITGAL 💬	D03959 💬	Efalizumab	[9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
426	Malaria 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
427	Malaria 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
428	MAPK signaling pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
429	MAPK signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
430	MAPK signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
431	MAPK signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
432	MAPK signaling pathway 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
433	MAPK signaling pathway 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
434	Measles 💬	[2] IL12A, IL12B 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
435	Measles 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
436	Measles 💬	[3] JAK1, JAK3, TYK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
437	Measles 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
438	Measles 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
439	Measles 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
440	Melanoma 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
441	Melanoma 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
442	Metabolic pathways 💬	[2] DHFR, DHFR2 💬	D00142 💬	Methotrexate	[35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
443	Metabolic pathways 💬	[2] DHFR, DHFR2 💬	D02115 💬	Methotrexate	[35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
444	Metabolic pathways 💬	[1] DHODH 💬	D00749 💬	Leflunomide	[10] 11, 40, 46, 49, 53, 66, 162, 224, 271, 300 💬
445	Metabolic pathways 💬	[2] IMPDH1, IMPDH2 💬	D01392 💬	Mizoribine	[8] 46, 49, 51, 53, 66, 94, 222, 224 💬
446	Metabolic pathways 💬	[2] IMPDH1, IMPDH2 💬	D00752 💬	Mycophenolate mofetil	[32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
447	Metabolic pathways 💬	[2] IMPDH1, IMPDH2 💬	D05094 💬	Mycophenolate mofetil	[32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
448	Metabolic pathways 💬	[2] IMPDH1, IMPDH2 💬	D05095 💬	Mycophenolate mofetil	[32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
449	Metabolic pathways 💬	[2] IMPDH1, IMPDH2 💬	D05096 💬	Mycophenolic acid	[34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
450	Metabolic pathways 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
451	Metabolic pathways 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
452	MicroRNAs in cancer 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
453	MicroRNAs in cancer 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
454	MicroRNAs in cancer 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
455	Mineral absorption 💬	[1] VDR 💬	D00188 💬	Cholecalciferol	[23] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 162, 202, 228, 271, 298, 299 💬
456	mTOR signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
457	mTOR signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
458	mTOR signaling pathway 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
459	mTOR signaling pathway 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
460	Natural killer cell mediated cytotoxicity 💬	[1] ITGAL 💬	D03959 💬	Efalizumab	[9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
461	Natural killer cell mediated cytotoxicity 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
462	Natural killer cell mediated cytotoxicity 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
463	Natural killer cell mediated cytotoxicity 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
464	Natural killer cell mediated cytotoxicity 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
465	Natural killer cell mediated cytotoxicity 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
466	Natural killer cell mediated cytotoxicity 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
467	Natural killer cell mediated cytotoxicity 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
468	Necroptosis 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
469	Necroptosis 💬	[4] JAK1, JAK2, JAK3, TYK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
470	Necroptosis 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
471	Necroptosis 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
472	Neuroactive ligand-receptor interaction 💬	[2] CHRM2, CHRM3 💬	D00525 💬	Pilocarpine	[3] 6 , 53, 299 💬
473	Neuroactive ligand-receptor interaction 💬	[2] CHRM2, CHRM3 💬	D02200 💬	Pilocarpine	[3] 6 , 53, 299 💬
474	Neuroactive ligand-receptor interaction 💬	[2] CHRM2, CHRM3 💬	D05478 💬	Pilocarpine	[3] 6 , 53, 299 💬
475	Neuroactive ligand-receptor interaction 💬	[1] CHRM3 💬	D00661 💬	Cevimeline	[1] 53 💬
476	Neuroactive ligand-receptor interaction 💬	[1] CHRM3 💬	D07667 💬	Cevimeline	[1] 53 💬
477	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D00292 💬	Dexamethasone	[25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
478	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D00975 💬	Dexamethasone	[25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
479	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D01510 💬	Dexamethasone	[25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
480	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D01615 💬	Dexamethasone	[25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
481	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D01632 💬	Dexamethasone	[25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
482	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D01948 💬	Dexamethasone	[25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
483	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D02174 💬	Dexamethasone	[25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
484	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D02591 💬	Dexamethasone	[25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
485	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D02592 💬	Dexamethasone	[25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
486	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D00088 💬	Hydrocortisone	[9] 6 , 46, 53, 75, 78, 81, 83, 97, 299 💬
487	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D05000 💬	Methylprednisolone hemisuccinate	[7] 13, 49, 50, 51, 53, 97, 211 💬
488	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D00473 💬	Prednisone	[47] 2 , 6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 93, 95, 96, 97, 113, 127, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬
489	Neurotrophin signaling pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
490	Neurotrophin signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
491	Neurotrophin signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
492	Neutrophil extracellular trap formation 💬	[1] ITGAL 💬	D03959 💬	Efalizumab	[9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
493	Neutrophil extracellular trap formation 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
494	Neutrophil extracellular trap formation 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
495	Neutrophil extracellular trap formation 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
496	NF-kappa B signaling pathway 💬	[1] BTK 💬	D11478 💬	Branebrutinib	[3] 46, 49, 53 💬
497	NF-kappa B signaling pathway 💬	[1] CD40 💬	D11610 💬	Iscalimab	[2] 49, 53 💬
498	NF-kappa B signaling pathway 💬	[2] LTA, TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
499	NF-kappa B signaling pathway 💬	[1] LTB 💬	D08866 💬	Baminercept	[4] 13, 46, 53, 97 💬
500	NF-kappa B signaling pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
501	NF-kappa B signaling pathway 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
502	NF-kappa B signaling pathway 💬	[1] TNFSF13B 💬	D03068 💬	Belimumab	[10] 11, 43, 44, 46, 49, 51, 53, 66, 222, 300 💬
503	NF-kappa B signaling pathway 💬	[1] TNFSF13B 💬	D11127 💬	Tibulizumab	[1] 53 💬
504	NOD-like receptor signaling pathway 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
505	NOD-like receptor signaling pathway 💬	[2] JAK1, TYK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
506	NOD-like receptor signaling pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
507	NOD-like receptor signaling pathway 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
508	NOD-like receptor signaling pathway 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
509	Non-alcoholic fatty liver disease 💬	[1] IL6R 💬	D02596 💬	Tocilizumab	[18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
510	Non-alcoholic fatty liver disease 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
511	Non-alcoholic fatty liver disease 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
512	Non-alcoholic fatty liver disease 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
513	Non-alcoholic fatty liver disease 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
514	Non-alcoholic fatty liver disease 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
515	Non-small cell lung cancer 💬	[1] JAK3 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
516	Non-small cell lung cancer 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
517	Non-small cell lung cancer 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
518	Non-small cell lung cancer 💬	[1] RARB 💬	D06543 💬	Vitamin A	[3] 13, 53, 90 💬
519	One carbon pool by folate 💬	[2] DHFR, DHFR2 💬	D00142 💬	Methotrexate	[35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
520	One carbon pool by folate 💬	[2] DHFR, DHFR2 💬	D02115 💬	Methotrexate	[35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
521	Oocyte meiosis 💬	[1] AR 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
522	Oocyte meiosis 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
523	Oocyte meiosis 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
524	Oocyte meiosis 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
525	Osteoclast differentiation 💬	[1] BTK 💬	D11478 💬	Branebrutinib	[3] 46, 49, 53 💬
526	Osteoclast differentiation 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
527	Osteoclast differentiation 💬	[2] JAK1, TYK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
528	Osteoclast differentiation 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
529	Osteoclast differentiation 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
530	Osteoclast differentiation 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
531	Osteoclast differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
532	Osteoclast differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
533	Osteoclast differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
534	Osteoclast differentiation 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
535	Osteoclast differentiation 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
536	Oxytocin signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
537	Oxytocin signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
538	Oxytocin signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
539	Pancreatic cancer 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
540	Pancreatic cancer 💬	[1] JAK1 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
541	Pancreatic cancer 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
542	Pancreatic cancer 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
543	Pancreatic cancer 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
544	Pancreatic secretion 💬	[1] CHRM3 💬	D00661 💬	Cevimeline	[1] 53 💬
545	Pancreatic secretion 💬	[1] CHRM3 💬	D07667 💬	Cevimeline	[1] 53 💬
546	Pancreatic secretion 💬	[1] CHRM3 💬	D00525 💬	Pilocarpine	[3] 6 , 53, 299 💬
547	Pancreatic secretion 💬	[1] CHRM3 💬	D02200 💬	Pilocarpine	[3] 6 , 53, 299 💬
548	Pancreatic secretion 💬	[1] CHRM3 💬	D05478 💬	Pilocarpine	[3] 6 , 53, 299 💬
549	Parathyroid hormone synthesis, secretion and action 💬	[1] VDR 💬	D00188 💬	Cholecalciferol	[23] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 162, 202, 228, 271, 298, 299 💬
550	Pathogenic Escherichia coli infection 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
551	Pathogenic Escherichia coli infection 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
552	Pathogenic Escherichia coli infection 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
553	Pathways in cancer 💬	[3] AR, ESR1, ESR2 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
554	Pathways in cancer 💬	[2] ESR1, ESR2 💬	D11513 💬	Estetrol	[1] 53 💬
555	Pathways in cancer 💬	[2] ESR1, ESR2 💬	D11514 💬	Estetrol	[1] 53 💬
556	Pathways in cancer 💬	[3] IL12A, IL12B, IL23A 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
557	Pathways in cancer 💬	[1] IL6R 💬	D02596 💬	Tocilizumab	[18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
558	Pathways in cancer 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
559	Pathways in cancer 💬	[3] JAK1, JAK2, JAK3 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
560	Pathways in cancer 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
561	Pathways in cancer 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
562	Pathways in cancer 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
563	Pathways in cancer 💬	[2] RARA, RARB 💬	D06543 💬	Vitamin A	[3] 13, 53, 90 💬
564	Pathways of neurodegeneration - multiple diseases 💬	[1] CHRM3 💬	D00661 💬	Cevimeline	[1] 53 💬
565	Pathways of neurodegeneration - multiple diseases 💬	[1] CHRM3 💬	D07667 💬	Cevimeline	[1] 53 💬
566	Pathways of neurodegeneration - multiple diseases 💬	[1] CHRM3 💬	D00525 💬	Pilocarpine	[3] 6 , 53, 299 💬
567	Pathways of neurodegeneration - multiple diseases 💬	[1] CHRM3 💬	D02200 💬	Pilocarpine	[3] 6 , 53, 299 💬
568	Pathways of neurodegeneration - multiple diseases 💬	[1] CHRM3 💬	D05478 💬	Pilocarpine	[3] 6 , 53, 299 💬
569	Pathways of neurodegeneration - multiple diseases 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
570	Pathways of neurodegeneration - multiple diseases 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
571	Pathways of neurodegeneration - multiple diseases 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
572	Pathways of neurodegeneration - multiple diseases 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
573	Pathways of neurodegeneration - multiple diseases 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
574	Pathways of neurodegeneration - multiple diseases 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
575	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
576	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	[2] JAK1, JAK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
577	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
578	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	[1] PDCD1 💬	D10316 💬	Nivolumab	[12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
579	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
580	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
581	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
582	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
583	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
584	Pertussis 💬	[3] IL12A, IL12B, IL23A 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
585	Pertussis 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
586	Pertussis 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
587	Pertussis 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
588	Phosphatidylinositol signaling system 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
589	Phosphatidylinositol signaling system 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
590	Phospholipase D signaling pathway 💬	[1] FCER1A 💬	D05251 💬	Omalizumab	[7] 46, 53, 65, 98, 162, 226, 299 💬
591	Phospholipase D signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
592	Phospholipase D signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
593	PI3K-Akt signaling pathway 💬	[1] CHRM2 💬	D00525 💬	Pilocarpine	[3] 6 , 53, 299 💬
594	PI3K-Akt signaling pathway 💬	[1] CHRM2 💬	D02200 💬	Pilocarpine	[3] 6 , 53, 299 💬
595	PI3K-Akt signaling pathway 💬	[1] CHRM2 💬	D05478 💬	Pilocarpine	[3] 6 , 53, 299 💬
596	PI3K-Akt signaling pathway 💬	[1] IL6R 💬	D02596 💬	Tocilizumab	[18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
597	PI3K-Akt signaling pathway 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
598	PI3K-Akt signaling pathway 💬	[3] JAK1, JAK2, JAK3 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
599	PI3K-Akt signaling pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
600	PI3K-Akt signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
601	PI3K-Akt signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
602	Platelet activation 💬	[1] BTK 💬	D11478 💬	Branebrutinib	[3] 46, 49, 53 💬
603	Platelet activation 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
604	Platelet activation 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
605	Platinum drug resistance 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
606	Platinum drug resistance 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
607	Primary immunodeficiency 💬	[1] BTK 💬	D11478 💬	Branebrutinib	[3] 46, 49, 53 💬
608	Primary immunodeficiency 💬	[1] CD40 💬	D11610 💬	Iscalimab	[2] 49, 53 💬
609	Primary immunodeficiency 💬	[1] JAK3 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
610	Prion disease 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
611	Prion disease 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
612	Prion disease 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
613	Prion disease 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
614	Prion disease 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
615	Prion disease 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
616	Prion disease 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
617	Progesterone-mediated oocyte maturation 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
618	Progesterone-mediated oocyte maturation 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
619	Prolactin signaling pathway 💬	[2] ESR1, ESR2 💬	D11513 💬	Estetrol	[1] 53 💬
620	Prolactin signaling pathway 💬	[2] ESR1, ESR2 💬	D11514 💬	Estetrol	[1] 53 💬
621	Prolactin signaling pathway 💬	[2] ESR1, ESR2 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
622	Prolactin signaling pathway 💬	[1] JAK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
623	Prolactin signaling pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
624	Prolactin signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
625	Prolactin signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
626	Prostate cancer 💬	[1] AR 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
627	Prostate cancer 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
628	Prostate cancer 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
629	Prostate cancer 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
630	Proteoglycans in cancer 💬	[1] ESR1 💬	D11513 💬	Estetrol	[1] 53 💬
631	Proteoglycans in cancer 💬	[1] ESR1 💬	D11514 💬	Estetrol	[1] 53 💬
632	Proteoglycans in cancer 💬	[1] ESR1 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
633	Proteoglycans in cancer 💬	[1] IL12B 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
634	Proteoglycans in cancer 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
635	Proteoglycans in cancer 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
636	Proteoglycans in cancer 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
637	Proteoglycans in cancer 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
638	Purine metabolism 💬	[2] IMPDH1, IMPDH2 💬	D01392 💬	Mizoribine	[8] 46, 49, 51, 53, 66, 94, 222, 224 💬
639	Purine metabolism 💬	[2] IMPDH1, IMPDH2 💬	D00752 💬	Mycophenolate mofetil	[32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
640	Purine metabolism 💬	[2] IMPDH1, IMPDH2 💬	D05094 💬	Mycophenolate mofetil	[32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
641	Purine metabolism 💬	[2] IMPDH1, IMPDH2 💬	D05095 💬	Mycophenolate mofetil	[32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
642	Purine metabolism 💬	[2] IMPDH1, IMPDH2 💬	D05096 💬	Mycophenolic acid	[34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
643	Pyrimidine metabolism 💬	[1] DHODH 💬	D00749 💬	Leflunomide	[10] 11, 40, 46, 49, 53, 66, 162, 224, 271, 300 💬
644	Rap1 signaling pathway 💬	[1] ITGAL 💬	D03959 💬	Efalizumab	[9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
645	Rap1 signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
646	Rap1 signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
647	Ras signaling pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
648	Ras signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
649	Ras signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
650	Regulation of actin cytoskeleton 💬	[2] CHRM2, CHRM3 💬	D00525 💬	Pilocarpine	[3] 6 , 53, 299 💬
651	Regulation of actin cytoskeleton 💬	[2] CHRM2, CHRM3 💬	D02200 💬	Pilocarpine	[3] 6 , 53, 299 💬
652	Regulation of actin cytoskeleton 💬	[2] CHRM2, CHRM3 💬	D05478 💬	Pilocarpine	[3] 6 , 53, 299 💬
653	Regulation of actin cytoskeleton 💬	[1] CHRM3 💬	D00661 💬	Cevimeline	[1] 53 💬
654	Regulation of actin cytoskeleton 💬	[1] CHRM3 💬	D07667 💬	Cevimeline	[1] 53 💬
655	Regulation of actin cytoskeleton 💬	[1] ITGAL 💬	D03959 💬	Efalizumab	[9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
656	Regulation of actin cytoskeleton 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
657	Regulation of actin cytoskeleton 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
658	Regulation of lipolysis in adipocytes 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
659	Regulation of lipolysis in adipocytes 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
660	Relaxin signaling pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
661	Relaxin signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
662	Relaxin signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
663	Renal cell carcinoma 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
664	Renal cell carcinoma 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
665	Renin secretion 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
666	Renin secretion 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
667	Renin secretion 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
668	Rheumatoid arthritis 💬	[2] CD80, CD86 💬	D03203 💬	Abatacept	[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
669	Rheumatoid arthritis 💬	[2] IL17A, TNFSF13B 💬	D11127 💬	Tibulizumab	[1] 53 💬
670	Rheumatoid arthritis 💬	[1] IL23A 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
671	Rheumatoid arthritis 💬	[1] ITGAL 💬	D03959 💬	Efalizumab	[9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
672	Rheumatoid arthritis 💬	[1] LTB 💬	D08866 💬	Baminercept	[4] 13, 46, 53, 97 💬
673	Rheumatoid arthritis 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
674	Rheumatoid arthritis 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
675	Rheumatoid arthritis 💬	[1] TNFSF13B 💬	D03068 💬	Belimumab	[10] 11, 43, 44, 46, 49, 51, 53, 66, 222, 300 💬
676	RIG-I-like receptor signaling pathway 💬	[2] IL12A, IL12B 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
677	RIG-I-like receptor signaling pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
678	RIG-I-like receptor signaling pathway 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
679	RIG-I-like receptor signaling pathway 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
680	Salivary secretion 💬	[1] CHRM3 💬	D00661 💬	Cevimeline	[1] 53 💬
681	Salivary secretion 💬	[1] CHRM3 💬	D07667 💬	Cevimeline	[1] 53 💬
682	Salivary secretion 💬	[1] CHRM3 💬	D00525 💬	Pilocarpine	[3] 6 , 53, 299 💬
683	Salivary secretion 💬	[1] CHRM3 💬	D02200 💬	Pilocarpine	[3] 6 , 53, 299 💬
684	Salivary secretion 💬	[1] CHRM3 💬	D05478 💬	Pilocarpine	[3] 6 , 53, 299 💬
685	Salmonella infection 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
686	Salmonella infection 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
687	Salmonella infection 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
688	Salmonella infection 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
689	Salmonella infection 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
690	Shigellosis 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
691	Shigellosis 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
692	Shigellosis 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
693	Shigellosis 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
694	Shigellosis 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
695	Signaling pathways regulating pluripotency of stem cells 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
696	Signaling pathways regulating pluripotency of stem cells 💬	[3] JAK1, JAK2, JAK3 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
697	Signaling pathways regulating pluripotency of stem cells 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
698	Signaling pathways regulating pluripotency of stem cells 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
699	Small cell lung cancer 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
700	Small cell lung cancer 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
701	Small cell lung cancer 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
702	Small cell lung cancer 💬	[1] RARB 💬	D06543 💬	Vitamin A	[3] 13, 53, 90 💬
703	Sphingolipid signaling pathway 💬	[1] FCER1A 💬	D05251 💬	Omalizumab	[7] 46, 53, 65, 98, 162, 226, 299 💬
704	Sphingolipid signaling pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
705	Sphingolipid signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
706	Sphingolipid signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
707	Sphingolipid signaling pathway 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
708	Sphingolipid signaling pathway 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
709	Spinocerebellar ataxia 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
710	Spinocerebellar ataxia 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
711	Staphylococcus aureus infection 💬	[1] ITGAL 💬	D03959 💬	Efalizumab	[9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
712	Systemic lupus erythematosus 💬	[1] CD40 💬	D11610 💬	Iscalimab	[2] 49, 53 💬
713	Systemic lupus erythematosus 💬	[2] CD80, CD86 💬	D03203 💬	Abatacept	[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
714	Systemic lupus erythematosus 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
715	Systemic lupus erythematosus 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
716	T cell receptor signaling pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
717	T cell receptor signaling pathway 💬	[1] PDCD1 💬	D10316 💬	Nivolumab	[12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
718	T cell receptor signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
719	T cell receptor signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
720	T cell receptor signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
721	T cell receptor signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
722	T cell receptor signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
723	T cell receptor signaling pathway 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
724	T cell receptor signaling pathway 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
725	Taste transduction 💬	[1] CHRM3 💬	D00661 💬	Cevimeline	[1] 53 💬
726	Taste transduction 💬	[1] CHRM3 💬	D07667 💬	Cevimeline	[1] 53 💬
727	Taste transduction 💬	[1] CHRM3 💬	D00525 💬	Pilocarpine	[3] 6 , 53, 299 💬
728	Taste transduction 💬	[1] CHRM3 💬	D02200 💬	Pilocarpine	[3] 6 , 53, 299 💬
729	Taste transduction 💬	[1] CHRM3 💬	D05478 💬	Pilocarpine	[3] 6 , 53, 299 💬
730	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D01450 💬	Bupivacaine	[8] 46, 51, 53, 70, 96, 168, 226, 298 💬
731	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D07552 💬	Bupivacaine	[8] 46, 51, 53, 70, 96, 168, 226, 298 💬
732	TGF-beta signaling pathway 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
733	TGF-beta signaling pathway 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
734	Th1 and Th2 cell differentiation 💬	[2] IL12A, IL12B 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
735	Th1 and Th2 cell differentiation 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
736	Th1 and Th2 cell differentiation 💬	[4] JAK1, JAK2, JAK3, TYK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
737	Th1 and Th2 cell differentiation 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
738	Th1 and Th2 cell differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
739	Th1 and Th2 cell differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
740	Th1 and Th2 cell differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
741	Th17 cell differentiation 💬	[1] IL17A 💬	D11127 💬	Tibulizumab	[1] 53 💬
742	Th17 cell differentiation 💬	[1] IL23A 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
743	Th17 cell differentiation 💬	[1] IL6R 💬	D02596 💬	Tocilizumab	[18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
744	Th17 cell differentiation 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
745	Th17 cell differentiation 💬	[4] JAK1, JAK2, JAK3, TYK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
746	Th17 cell differentiation 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
747	Th17 cell differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
748	Th17 cell differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
749	Th17 cell differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
750	Th17 cell differentiation 💬	[1] RARA 💬	D06543 💬	Vitamin A	[3] 13, 53, 90 💬
751	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D11513 💬	Estetrol	[1] 53 💬
752	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D11514 💬	Estetrol	[1] 53 💬
753	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
754	Thyroid hormone signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
755	Thyroid hormone signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
756	TNF signaling pathway 💬	[2] LTA, TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
757	TNF signaling pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
758	TNF signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
759	TNF signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
760	TNF signaling pathway 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
761	Toll-like receptor signaling pathway 💬	[1] CD40 💬	D11610 💬	Iscalimab	[2] 49, 53 💬
762	Toll-like receptor signaling pathway 💬	[2] CD80, CD86 💬	D03203 💬	Abatacept	[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
763	Toll-like receptor signaling pathway 💬	[2] IL12A, IL12B 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
764	Toll-like receptor signaling pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
765	Toll-like receptor signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
766	Toll-like receptor signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
767	Toll-like receptor signaling pathway 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
768	Toll-like receptor signaling pathway 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
769	Toxoplasmosis 💬	[1] CD40 💬	D11610 💬	Iscalimab	[2] 49, 53 💬
770	Toxoplasmosis 💬	[2] IL12A, IL12B 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
771	Toxoplasmosis 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
772	Toxoplasmosis 💬	[3] JAK1, JAK2, TYK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
773	Toxoplasmosis 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
774	Toxoplasmosis 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
775	Toxoplasmosis 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
776	Transcriptional misregulation in cancer 💬	[1] CD40 💬	D11610 💬	Iscalimab	[2] 49, 53 💬
777	Transcriptional misregulation in cancer 💬	[1] CD86 💬	D03203 💬	Abatacept	[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
778	Transcriptional misregulation in cancer 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
779	Transcriptional misregulation in cancer 💬	[1] RARA 💬	D06543 💬	Vitamin A	[3] 13, 53, 90 💬
780	Tuberculosis 💬	[3] IL12A, IL12B, IL23A 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
781	Tuberculosis 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
782	Tuberculosis 💬	[2] JAK1, JAK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
783	Tuberculosis 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
784	Tuberculosis 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
785	Tuberculosis 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
786	Tuberculosis 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
787	Tuberculosis 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
788	Tuberculosis 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
789	Tuberculosis 💬	[1] VDR 💬	D00188 💬	Cholecalciferol	[23] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 162, 202, 228, 271, 298, 299 💬
790	Type I diabetes mellitus 💬	[2] CD80, CD86 💬	D03203 💬	Abatacept	[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
791	Type I diabetes mellitus 💬	[2] IL12A, IL12B 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
792	Type I diabetes mellitus 💬	[2] LTA, TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
793	Type I diabetes mellitus 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
794	Type II diabetes mellitus 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
795	Type II diabetes mellitus 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
796	Type II diabetes mellitus 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
797	Type II diabetes mellitus 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
798	VEGF signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
799	VEGF signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
800	VEGF signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
801	VEGF signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
802	VEGF signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
803	Viral carcinogenesis 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
804	Viral carcinogenesis 💬	[2] JAK1, JAK3 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
805	Viral carcinogenesis 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
806	Viral carcinogenesis 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
807	Viral carcinogenesis 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
808	Viral myocarditis 💬	[1] CD40 💬	D11610 💬	Iscalimab	[2] 49, 53 💬
809	Viral myocarditis 💬	[2] CD80, CD86 💬	D03203 💬	Abatacept	[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
810	Viral myocarditis 💬	[1] ITGAL 💬	D03959 💬	Efalizumab	[9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
811	Viral protein interaction with cytokine and cytokine receptor 💬	[1] IL6R 💬	D02596 💬	Tocilizumab	[18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
812	Viral protein interaction with cytokine and cytokine receptor 💬	[2] LTA, TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
813	Viral protein interaction with cytokine and cytokine receptor 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
814	Wnt signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
815	Wnt signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
816	Wnt signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
817	Yersinia infection 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
818	Yersinia infection 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
819	Yersinia infection 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
820	Yersinia infection 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
821	Yersinia infection 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬