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Target Gene/Pathway💬 Info on mouse-over

e.g. Sirolimus, Adalimumab, MAP2K

ABCDEFGH I JKLMNOPQRSTUVWXYZother

155 / 286 pathways

No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related		 KEGG GENES KEGG DRUG DrugBank Disease ID
1 Acute myeloid leukemia 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
2 Adipocytokine signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
3 Adipocytokine signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
4 Adipocytokine signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
5 Adipocytokine signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
6 African trypanosomiasis 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
7 AGE-RAGE signaling pathway in diabetic complications 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
8 Allograft rejection 💬
 [2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
9 Allograft rejection 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
10 Alzheimer disease 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
11 Alzheimer disease 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
12 Alzheimer disease 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
13 Alzheimer disease 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
14 Alzheimer disease 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
15 Alzheimer disease 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
16 Amoebiasis 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
17 Amphetamine addiction 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
18 Amphetamine addiction 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
19 Amphetamine addiction 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
20 AMPK signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
21 AMPK signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
22 AMPK signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
23 Amyotrophic lateral sclerosis 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
24 Amyotrophic lateral sclerosis 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
25 Amyotrophic lateral sclerosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
26 Amyotrophic lateral sclerosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
27 Amyotrophic lateral sclerosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
28 Amyotrophic lateral sclerosis 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
29 Antifolate resistance 💬
 [2] DHFR, DHFR2 💬 D00142 💬 Methotrexate [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
30 Antifolate resistance 💬
 [2] DHFR, DHFR2 💬 D02115 💬 Methotrexate [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
31 Antifolate resistance 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
32 Antigen processing and presentation 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
33 Apelin signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
34 Apelin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
35 Apelin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
36 Apoptosis 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
37 Apoptosis 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
38 Apoptosis - multiple species 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
39 Asthma 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
40 Autoimmune thyroid disease 💬
 [2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
41 Autophagy - animal 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
42 Autophagy - animal 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
43 Autophagy - animal 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
44 Autophagy - other 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
45 Axon guidance 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
46 Axon guidance 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
47 Axon guidance 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
48 B cell receptor signaling pathway 💬
 [1] BTK 💬 D10223 💬 Ibrutinib [3] 28, 60, 61 💬
49 B cell receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
50 B cell receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
51 B cell receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
52 Biosynthesis of cofactors 💬
 [2] DHFR, DHFR2 💬 D00142 💬 Methotrexate [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
53 Biosynthesis of cofactors 💬
 [2] DHFR, DHFR2 💬 D02115 💬 Methotrexate [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
54 Breast cancer 💬
 [2] ESR1, PGR 💬 D00289 💬 Danazol [5] 60, 63, 64, 65, 285 💬
55 Breast cancer 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
56 Breast cancer 💬
 [1] PGR 💬 D00951 💬 Medroxyprogesterone acetate [3] 49, 51, 60 💬
57 Breast cancer 💬
 [1] PGR 💬 D08166 💬 Medroxyprogesterone acetate [3] 49, 51, 60 💬
58 C-type lectin receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
59 C-type lectin receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
60 C-type lectin receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
61 C-type lectin receptor signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
62 Calcium signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
63 Calcium signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
64 Calcium signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
65 Cell adhesion molecules 💬
 [1] CD58 💬 D02800 💬 Alefacept [6] 37, 60, 65, 164, 284, 285 💬
66 Cell adhesion molecules 💬
 [2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
67 Cellular senescence 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
68 Cellular senescence 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
69 Cellular senescence 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
70 Cellular senescence 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
71 Central carbon metabolism in cancer 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
72 cGMP-PKG signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
73 cGMP-PKG signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
74 cGMP-PKG signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
75 Chagas disease 💬
 [3] CD3D, CD3E, CD3G 💬 D05092 💬 Muromonab [3] 60, 96, 97 💬
76 Chagas disease 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
77 Choline metabolism in cancer 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
78 Circadian rhythm 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
79 Circadian rhythm 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
80 Colorectal cancer 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
81 Colorectal cancer 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
82 Complement and coagulation cascades 💬
 [1] SERPINC1 💬 D07510 💬 Heparin [11] 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317 💬
83 Coronavirus disease - COVID-19 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
84 Coronavirus disease - COVID-19 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
85 Cytokine-cytokine receptor interaction 💬
 [1] CSF2RA 💬 D05803 💬 Sargramostim [7]  6 , 28, 60, 62, 96, 229, 285 💬
86 Cytokine-cytokine receptor interaction 💬
 [1] CSF3R 💬 D03235 💬 Filgrastim [33]  2 ,  6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
87 Cytokine-cytokine receptor interaction 💬
 [1] CSF3R 💬 D06889 💬 Pegfilgrastim [1] 60 💬
88 Cytokine-cytokine receptor interaction 💬
 [1] IL2RA 💬 D03639 💬 Daclizumab [7] 13, 56, 60, 65, 97, 283, 284 💬
89 Cytokine-cytokine receptor interaction 💬
 [2] LTA, TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
90 Cytokine-cytokine receptor interaction 💬
 [1] MPL 💬 D08990 💬 Romiplostim [4] 60, 63, 64, 65 💬
91 Diabetic cardiomyopathy 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
92 Dilated cardiomyopathy 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
93 DNA replication 💬
 [2] POLA1, POLA2 💬 D03546 💬 Clofarabine [9] 19, 20, 40, 46, 49, 60, 96, 234, 326 💬
94 Dopaminergic synapse 💬
 [3] PPP3CA, PPP3CB, PPP3CC 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
95 Dopaminergic synapse 💬
 [3] PPP3CA, PPP3CB, PPP3CC 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
96 Dopaminergic synapse 💬
 [3] PPP3CA, PPP3CB, PPP3CC 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
97 Drug metabolism - other enzymes 💬
 [2] IMPDH1, IMPDH2 💬 D00752 💬 Mycophenolate mofetil [32]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
98 Drug metabolism - other enzymes 💬
 [2] IMPDH1, IMPDH2 💬 D05094 💬 Mycophenolate mofetil [32]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
99 Drug metabolism - other enzymes 💬
 [2] IMPDH1, IMPDH2 💬 D05095 💬 Mycophenolate mofetil [32]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
100 Drug metabolism - other enzymes 💬
 [2] IMPDH1, IMPDH2 💬 D05096 💬 Mycophenolic acid [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
101 Drug metabolism - other enzymes 💬
 [1] RRM1 💬 D03546 💬 Clofarabine [9] 19, 20, 40, 46, 49, 60, 96, 234, 326 💬
102 Drug metabolism - other enzymes 💬
 [1] RRM1 💬 D01907 💬 Fludarabine [18] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬
103 Drug metabolism - other enzymes 💬
 [1] RRM1 💬 D07966 💬 Fludarabine [18] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬
104 EGFR tyrosine kinase inhibitor resistance 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
105 EGFR tyrosine kinase inhibitor resistance 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
106 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D00289 💬 Danazol [5] 60, 63, 64, 65, 285 💬
107 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] VDR 💬 D00188 💬 Cholecalciferol [23]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 162, 202, 228, 271, 298, 299 💬
108 Endocrine resistance 💬
 [1] ESR1 💬 D00289 💬 Danazol [5] 60, 63, 64, 65, 285 💬
109 Endocrine resistance 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
110 Endocytosis 💬
 [1] IL2RA 💬 D03639 💬 Daclizumab [7] 13, 56, 60, 65, 97, 283, 284 💬
111 Endometrial cancer 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
112 Epstein-Barr virus infection 💬
 [1] BTK 💬 D10223 💬 Ibrutinib [3] 28, 60, 61 💬
113 Epstein-Barr virus infection 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
114 Epstein-Barr virus infection 💬
 [3] CD3D, CD3E, CD3G 💬 D05092 💬 Muromonab [3] 60, 96, 97 💬
115 Epstein-Barr virus infection 💬
 [1] CD58 💬 D02800 💬 Alefacept [6] 37, 60, 65, 164, 284, 285 💬
116 Epstein-Barr virus infection 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
117 Epstein-Barr virus infection 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
118 ErbB signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
119 Estrogen signaling pathway 💬
 [2] ESR1, PGR 💬 D00289 💬 Danazol [5] 60, 63, 64, 65, 285 💬
120 Estrogen signaling pathway 💬
 [1] PGR 💬 D00951 💬 Medroxyprogesterone acetate [3] 49, 51, 60 💬
121 Estrogen signaling pathway 💬
 [1] PGR 💬 D08166 💬 Medroxyprogesterone acetate [3] 49, 51, 60 💬
122 Fc epsilon RI signaling pathway 💬
 [1] BTK 💬 D10223 💬 Ibrutinib [3] 28, 60, 61 💬
123 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
124 Fluid shear stress and atherosclerosis 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
125 Fluid shear stress and atherosclerosis 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
126 Fluid shear stress and atherosclerosis 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
127 Folate biosynthesis 💬
 [2] DHFR, DHFR2 💬 D00142 💬 Methotrexate [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
128 Folate biosynthesis 💬
 [2] DHFR, DHFR2 💬 D02115 💬 Methotrexate [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
129 FoxO signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
130 FoxO signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
131 Gastric cancer 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
132 Glioma 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
133 Glucagon signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
134 Glucagon signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
135 Glucagon signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
136 Glucagon signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
137 Glucagon signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
138 Glutamatergic synapse 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
139 Glutamatergic synapse 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
140 Glutamatergic synapse 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
141 Glutathione metabolism 💬
 [1] RRM1 💬 D03546 💬 Clofarabine [9] 19, 20, 40, 46, 49, 60, 96, 234, 326 💬
142 Glutathione metabolism 💬
 [1] RRM1 💬 D01907 💬 Fludarabine [18] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬
143 Glutathione metabolism 💬
 [1] RRM1 💬 D07966 💬 Fludarabine [18] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬
144 Graft-versus-host disease 💬
 [2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
145 Graft-versus-host disease 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
146 Growth hormone synthesis, secretion and action 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
147 Hematopoietic cell lineage 💬
 [3] CD3D, CD3E, CD3G 💬 D05092 💬 Muromonab [3] 60, 96, 97 💬
148 Hematopoietic cell lineage 💬
 [1] CSF2RA 💬 D05803 💬 Sargramostim [7]  6 , 28, 60, 62, 96, 229, 285 💬
149 Hematopoietic cell lineage 💬
 [1] CSF3R 💬 D03235 💬 Filgrastim [33]  2 ,  6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
150 Hematopoietic cell lineage 💬
 [1] CSF3R 💬 D06889 💬 Pegfilgrastim [1] 60 💬
151 Hematopoietic cell lineage 💬
 [1] IL2RA 💬 D03639 💬 Daclizumab [7] 13, 56, 60, 65, 97, 283, 284 💬
152 Hematopoietic cell lineage 💬
 [1] MS4A1 💬 D02994 💬 Rituximab [47] 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
153 Hematopoietic cell lineage 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
154 Hepatitis B 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
155 Hepatitis B 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
156 Hepatitis B 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
157 Hepatitis C 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
158 Hepatitis C 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
159 Hepatitis C 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
160 Hepatocellular carcinoma 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
161 Herpes simplex virus 1 infection 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
162 Herpes simplex virus 1 infection 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
163 Herpes simplex virus 1 infection 💬
 [2] LTA, TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
164 Herpes simplex virus 1 infection 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
165 HIF-1 signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
166 Human cytomegalovirus infection 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
167 Human cytomegalovirus infection 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
168 Human cytomegalovirus infection 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
169 Human cytomegalovirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
170 Human cytomegalovirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
171 Human cytomegalovirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
172 Human cytomegalovirus infection 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
173 Human immunodeficiency virus 1 infection 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
174 Human immunodeficiency virus 1 infection 💬
 [3] CD3D, CD3E, CD3G 💬 D05092 💬 Muromonab [3] 60, 96, 97 💬
175 Human immunodeficiency virus 1 infection 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
176 Human immunodeficiency virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
177 Human immunodeficiency virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
178 Human immunodeficiency virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
179 Human immunodeficiency virus 1 infection 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
180 Human papillomavirus infection 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
181 Human papillomavirus infection 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
182 Human papillomavirus infection 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
183 Human T-cell leukemia virus 1 infection 💬
 [3] CD3D, CD3E, CD3G 💬 D05092 💬 Muromonab [3] 60, 96, 97 💬
184 Human T-cell leukemia virus 1 infection 💬
 [1] IL2RA 💬 D03639 💬 Daclizumab [7] 13, 56, 60, 65, 97, 283, 284 💬
185 Human T-cell leukemia virus 1 infection 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
186 Human T-cell leukemia virus 1 infection 💬
 [2] LTA, TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
187 Human T-cell leukemia virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
188 Human T-cell leukemia virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
189 Human T-cell leukemia virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
190 Huntington disease 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
191 Huntington disease 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
192 Hypertrophic cardiomyopathy 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
193 Hypertrophic cardiomyopathy 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
194 Hypertrophic cardiomyopathy 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
195 IL-17 signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
196 Inflammatory bowel disease 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
197 Influenza A 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
198 Influenza A 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
199 Influenza A 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
200 Insulin resistance 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
201 Insulin resistance 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
202 Insulin resistance 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
203 Insulin resistance 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
204 Insulin signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
205 Insulin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
206 Insulin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
207 Intestinal immune network for IgA production 💬
 [2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
208 JAK-STAT signaling pathway 💬
 [1] CSF2RA 💬 D05803 💬 Sargramostim [7]  6 , 28, 60, 62, 96, 229, 285 💬
209 JAK-STAT signaling pathway 💬
 [1] CSF3R 💬 D03235 💬 Filgrastim [33]  2 ,  6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
210 JAK-STAT signaling pathway 💬
 [1] CSF3R 💬 D06889 💬 Pegfilgrastim [1] 60 💬
211 JAK-STAT signaling pathway 💬
 [1] IL2RA 💬 D03639 💬 Daclizumab [7] 13, 56, 60, 65, 97, 283, 284 💬
212 JAK-STAT signaling pathway 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
213 JAK-STAT signaling pathway 💬
 [1] MPL 💬 D08990 💬 Romiplostim [4] 60, 63, 64, 65 💬
214 JAK-STAT signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
215 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
216 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
217 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
218 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
219 Kaposi sarcoma-associated herpesvirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
220 Kaposi sarcoma-associated herpesvirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
221 Kaposi sarcoma-associated herpesvirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
222 Legionellosis 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
223 Legionellosis 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
224 Leishmaniasis 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
225 Leishmaniasis 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
226 Long-term potentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
227 Long-term potentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
228 Long-term potentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
229 Longevity regulating pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
230 Longevity regulating pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
231 Longevity regulating pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
232 Longevity regulating pathway - multiple species 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
233 Longevity regulating pathway - multiple species 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
234 Longevity regulating pathway - multiple species 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
235 Malaria 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
236 MAPK signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
237 MAPK signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
238 MAPK signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
239 MAPK signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
240 Measles 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
241 Measles 💬
 [3] CD3D, CD3E, CD3G 💬 D05092 💬 Muromonab [3] 60, 96, 97 💬
242 Measles 💬
 [1] IL2RA 💬 D03639 💬 Daclizumab [7] 13, 56, 60, 65, 97, 283, 284 💬
243 Measles 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
244 Metabolic pathways 💬
 [2] DHFR, DHFR2 💬 D00142 💬 Methotrexate [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
245 Metabolic pathways 💬
 [2] DHFR, DHFR2 💬 D02115 💬 Methotrexate [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
246 Metabolic pathways 💬
 [2] IMPDH1, IMPDH2 💬 D00752 💬 Mycophenolate mofetil [32]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
247 Metabolic pathways 💬
 [2] IMPDH1, IMPDH2 💬 D05094 💬 Mycophenolate mofetil [32]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
248 Metabolic pathways 💬
 [2] IMPDH1, IMPDH2 💬 D05095 💬 Mycophenolate mofetil [32]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
249 Metabolic pathways 💬
 [2] IMPDH1, IMPDH2 💬 D05096 💬 Mycophenolic acid [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
250 Metabolic pathways 💬
 [1] RRM1 💬 D03546 💬 Clofarabine [9] 19, 20, 40, 46, 49, 60, 96, 234, 326 💬
251 Metabolic pathways 💬
 [1] RRM1 💬 D01907 💬 Fludarabine [18] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬
252 Metabolic pathways 💬
 [1] RRM1 💬 D07966 💬 Fludarabine [18] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬
253 MicroRNAs in cancer 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
254 Mineral absorption 💬
 [1] VDR 💬 D00188 💬 Cholecalciferol [23]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 162, 202, 228, 271, 298, 299 💬
255 mTOR signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
256 mTOR signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
257 mTOR signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
258 mTOR signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
259 Natural killer cell mediated cytotoxicity 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
260 Natural killer cell mediated cytotoxicity 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
261 Natural killer cell mediated cytotoxicity 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
262 Natural killer cell mediated cytotoxicity 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
263 Necroptosis 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
264 Necroptosis 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
265 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00407 💬 Methylprednisolone [44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
266 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00751 💬 Methylprednisolone [44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
267 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00979 💬 Methylprednisolone [44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
268 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D05000 💬 Methylprednisolone [44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
269 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D05001 💬 Methylprednisolone [44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
270 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D05002 💬 Methylprednisolone [44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
271 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00472 💬 Prednisolone [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
272 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00980 💬 Prednisolone [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
273 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00981 💬 Prednisolone [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
274 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00982 💬 Prednisolone [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
275 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01239 💬 Prednisolone [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
276 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01998 💬 Prednisolone [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
277 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D02156 💬 Prednisolone [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
278 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D03301 💬 Prednisolone [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
279 Neutrophil extracellular trap formation 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
280 NF-kappa B signaling pathway 💬
 [1] BTK 💬 D10223 💬 Ibrutinib [3] 28, 60, 61 💬
281 NF-kappa B signaling pathway 💬
 [2] LTA, TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
282 NOD-like receptor signaling pathway 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
283 NOD-like receptor signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
284 Non-alcoholic fatty liver disease 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
285 Non-alcoholic fatty liver disease 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
286 Non-alcoholic fatty liver disease 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
287 Non-small cell lung cancer 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
288 One carbon pool by folate 💬
 [2] DHFR, DHFR2 💬 D00142 💬 Methotrexate [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
289 One carbon pool by folate 💬
 [2] DHFR, DHFR2 💬 D02115 💬 Methotrexate [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
290 Oocyte meiosis 💬
 [1] AR 💬 D08250 💬 Nandrolone [2] 60, 85 💬
291 Oocyte meiosis 💬
 [1] AR 💬 D00955 💬 Nandrolone decanoate [2] 60, 85 💬
292 Oocyte meiosis 💬
 [1] AR 💬 D00444 💬 Stanozolol [1] 60 💬
293 Oocyte meiosis 💬
 [1] AR 💬 D00075 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
294 Oocyte meiosis 💬
 [1] AR 💬 D00957 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
295 Oocyte meiosis 💬
 [1] AR 💬 D00958 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
296 Oocyte meiosis 💬
 [1] AR 💬 D00959 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
297 Oocyte meiosis 💬
 [1] AR 💬 D06085 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
298 Oocyte meiosis 💬
 [1] AR 💬 D06087 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
299 Oocyte meiosis 💬
 [1] AR 💬 D06087 💬 Testosterone undecanoate [2] 13, 60 💬
300 Oocyte meiosis 💬
 [2] AR, PGR 💬 D00289 💬 Danazol [5] 60, 63, 64, 65, 285 💬
301 Oocyte meiosis 💬
 [1] PGR 💬 D00951 💬 Medroxyprogesterone acetate [3] 49, 51, 60 💬
302 Oocyte meiosis 💬
 [1] PGR 💬 D08166 💬 Medroxyprogesterone acetate [3] 49, 51, 60 💬
303 Oocyte meiosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
304 Oocyte meiosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
305 Oocyte meiosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
306 Osteoclast differentiation 💬
 [1] BTK 💬 D10223 💬 Ibrutinib [3] 28, 60, 61 💬
307 Osteoclast differentiation 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
308 Osteoclast differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
309 Osteoclast differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
310 Osteoclast differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
311 Osteoclast differentiation 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
312 Oxytocin signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
313 Oxytocin signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
314 Oxytocin signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
315 Oxytocin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
316 Oxytocin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
317 p53 signaling pathway 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
318 Pancreatic cancer 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
319 Pancreatic cancer 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
320 Pancreatic cancer 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
321 Parathyroid hormone synthesis, secretion and action 💬
 [1] VDR 💬 D00188 💬 Cholecalciferol [23]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 162, 202, 228, 271, 298, 299 💬
322 Parkinson disease 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
323 Pathogenic Escherichia coli infection 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
324 Pathogenic Escherichia coli infection 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
325 Pathways in cancer 💬
 [1] AR 💬 D08250 💬 Nandrolone [2] 60, 85 💬
326 Pathways in cancer 💬
 [1] AR 💬 D00955 💬 Nandrolone decanoate [2] 60, 85 💬
327 Pathways in cancer 💬
 [1] AR 💬 D00444 💬 Stanozolol [1] 60 💬
328 Pathways in cancer 💬
 [1] AR 💬 D00075 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
329 Pathways in cancer 💬
 [1] AR 💬 D00957 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
330 Pathways in cancer 💬
 [1] AR 💬 D00958 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
331 Pathways in cancer 💬
 [1] AR 💬 D00959 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
332 Pathways in cancer 💬
 [1] AR 💬 D06085 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
333 Pathways in cancer 💬
 [1] AR 💬 D06087 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
334 Pathways in cancer 💬
 [1] AR 💬 D06087 💬 Testosterone undecanoate [2] 13, 60 💬
335 Pathways in cancer 💬
 [2] AR, ESR1 💬 D00289 💬 Danazol [5] 60, 63, 64, 65, 285 💬
336 Pathways in cancer 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
337 Pathways in cancer 💬
 [1] CSF2RA 💬 D05803 💬 Sargramostim [7]  6 , 28, 60, 62, 96, 229, 285 💬
338 Pathways in cancer 💬
 [1] CSF3R 💬 D03235 💬 Filgrastim [33]  2 ,  6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
339 Pathways in cancer 💬
 [1] CSF3R 💬 D06889 💬 Pegfilgrastim [1] 60 💬
340 Pathways in cancer 💬
 [1] IL2RA 💬 D03639 💬 Daclizumab [7] 13, 56, 60, 65, 97, 283, 284 💬
341 Pathways in cancer 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
342 Pathways in cancer 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
343 Pathways of neurodegeneration - multiple diseases 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
344 Pathways of neurodegeneration - multiple diseases 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
345 Pathways of neurodegeneration - multiple diseases 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
346 Pathways of neurodegeneration - multiple diseases 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
347 Pathways of neurodegeneration - multiple diseases 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
348 Pathways of neurodegeneration - multiple diseases 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
349 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [3] CD3D, CD3E, CD3G 💬 D05092 💬 Muromonab [3] 60, 96, 97 💬
350 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
351 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
352 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
353 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
354 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
355 Pertussis 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
356 Phospholipase D signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
357 PI3K-Akt signaling pathway 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
358 PI3K-Akt signaling pathway 💬
 [1] CSF3R 💬 D03235 💬 Filgrastim [33]  2 ,  6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
359 PI3K-Akt signaling pathway 💬
 [1] CSF3R 💬 D06889 💬 Pegfilgrastim [1] 60 💬
360 PI3K-Akt signaling pathway 💬
 [1] IL2RA 💬 D03639 💬 Daclizumab [7] 13, 56, 60, 65, 97, 283, 284 💬
361 PI3K-Akt signaling pathway 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
362 PI3K-Akt signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
363 PI3K-Akt signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
364 PI3K-Akt signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
365 Platelet activation 💬
 [1] BTK 💬 D10223 💬 Ibrutinib [3] 28, 60, 61 💬
366 Platinum drug resistance 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
367 Platinum drug resistance 💬
 [2] TOP2A, TOP2B 💬 D00125 💬 Etoposide [11] 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331 💬
368 Platinum drug resistance 💬
 [2] TOP2A, TOP2B 💬 D04107 💬 Etoposide [11] 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331 💬
369 Primary immunodeficiency 💬
 [1] BTK 💬 D10223 💬 Ibrutinib [3] 28, 60, 61 💬
370 Primary immunodeficiency 💬
 [2] CD3D, CD3E 💬 D05092 💬 Muromonab [3] 60, 96, 97 💬
371 Prion disease 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
372 Prion disease 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
373 Prion disease 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
374 Prion disease 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
375 Prion disease 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
376 Progesterone-mediated oocyte maturation 💬
 [1] PGR 💬 D00289 💬 Danazol [5] 60, 63, 64, 65, 285 💬
377 Progesterone-mediated oocyte maturation 💬
 [1] PGR 💬 D00951 💬 Medroxyprogesterone acetate [3] 49, 51, 60 💬
378 Progesterone-mediated oocyte maturation 💬
 [1] PGR 💬 D08166 💬 Medroxyprogesterone acetate [3] 49, 51, 60 💬
379 Prolactin signaling pathway 💬
 [1] ESR1 💬 D00289 💬 Danazol [5] 60, 63, 64, 65, 285 💬
380 Prostate cancer 💬
 [1] AR 💬 D00289 💬 Danazol [5] 60, 63, 64, 65, 285 💬
381 Prostate cancer 💬
 [1] AR 💬 D08250 💬 Nandrolone [2] 60, 85 💬
382 Prostate cancer 💬
 [1] AR 💬 D00955 💬 Nandrolone decanoate [2] 60, 85 💬
383 Prostate cancer 💬
 [1] AR 💬 D00444 💬 Stanozolol [1] 60 💬
384 Prostate cancer 💬
 [1] AR 💬 D00075 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
385 Prostate cancer 💬
 [1] AR 💬 D00957 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
386 Prostate cancer 💬
 [1] AR 💬 D00958 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
387 Prostate cancer 💬
 [1] AR 💬 D00959 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
388 Prostate cancer 💬
 [1] AR 💬 D06085 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
389 Prostate cancer 💬
 [1] AR 💬 D06087 💬 Testosterone [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
390 Prostate cancer 💬
 [1] AR 💬 D06087 💬 Testosterone undecanoate [2] 13, 60 💬
391 Prostate cancer 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
392 Prostate cancer 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
393 Proteoglycans in cancer 💬
 [1] ESR1 💬 D00289 💬 Danazol [5] 60, 63, 64, 65, 285 💬
394 Proteoglycans in cancer 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
395 Proteoglycans in cancer 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
396 Purine metabolism 💬
 [2] IMPDH1, IMPDH2 💬 D00752 💬 Mycophenolate mofetil [32]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
397 Purine metabolism 💬
 [2] IMPDH1, IMPDH2 💬 D05094 💬 Mycophenolate mofetil [32]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
398 Purine metabolism 💬
 [2] IMPDH1, IMPDH2 💬 D05095 💬 Mycophenolate mofetil [32]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
399 Purine metabolism 💬
 [2] IMPDH1, IMPDH2 💬 D05096 💬 Mycophenolic acid [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
400 Purine metabolism 💬
 [1] RRM1 💬 D03546 💬 Clofarabine [9] 19, 20, 40, 46, 49, 60, 96, 234, 326 💬
401 Purine metabolism 💬
 [1] RRM1 💬 D01907 💬 Fludarabine [18] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬
402 Purine metabolism 💬
 [1] RRM1 💬 D07966 💬 Fludarabine [18] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬
403 Pyrimidine metabolism 💬
 [1] RRM1 💬 D03546 💬 Clofarabine [9] 19, 20, 40, 46, 49, 60, 96, 234, 326 💬
404 Pyrimidine metabolism 💬
 [1] RRM1 💬 D01907 💬 Fludarabine [18] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬
405 Pyrimidine metabolism 💬
 [1] RRM1 💬 D07966 💬 Fludarabine [18] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬
406 Renin secretion 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
407 Renin secretion 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
408 Renin secretion 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
409 Rheumatoid arthritis 💬
 [2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
410 Rheumatoid arthritis 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
411 RIG-I-like receptor signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
412 Salmonella infection 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
413 Shigellosis 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
414 Shigellosis 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
415 Signaling pathways regulating pluripotency of stem cells 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
416 Small cell lung cancer 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
417 Sphingolipid signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
418 Spinocerebellar ataxia 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
419 Systemic lupus erythematosus 💬
 [2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
420 Systemic lupus erythematosus 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
421 T cell receptor signaling pathway 💬
 [3] CD3D, CD3E, CD3G 💬 D05092 💬 Muromonab [3] 60, 96, 97 💬
422 T cell receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
423 T cell receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
424 T cell receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
425 T cell receptor signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
426 TGF-beta signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
427 Th1 and Th2 cell differentiation 💬
 [3] CD3D, CD3E, CD3G 💬 D05092 💬 Muromonab [3] 60, 96, 97 💬
428 Th1 and Th2 cell differentiation 💬
 [1] IL2RA 💬 D03639 💬 Daclizumab [7] 13, 56, 60, 65, 97, 283, 284 💬
429 Th1 and Th2 cell differentiation 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
430 Th1 and Th2 cell differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
431 Th1 and Th2 cell differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
432 Th1 and Th2 cell differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
433 Th17 cell differentiation 💬
 [3] CD3D, CD3E, CD3G 💬 D05092 💬 Muromonab [3] 60, 96, 97 💬
434 Th17 cell differentiation 💬
 [1] IL2RA 💬 D03639 💬 Daclizumab [7] 13, 56, 60, 65, 97, 283, 284 💬
435 Th17 cell differentiation 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
436 Th17 cell differentiation 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
437 Th17 cell differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
438 Th17 cell differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
439 Th17 cell differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
440 Thermogenesis 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
441 Thermogenesis 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
442 Thermogenesis 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
443 Thyroid hormone signaling pathway 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
444 Thyroid hormone signaling pathway 💬
 [1] ESR1 💬 D00289 💬 Danazol [5] 60, 63, 64, 65, 285 💬
445 Thyroid hormone signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
446 Tight junction 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
447 Tight junction 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
448 TNF signaling pathway 💬
 [2] LTA, TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
449 Toll-like receptor signaling pathway 💬
 [2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
450 Toll-like receptor signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
451 Toxoplasmosis 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
452 Toxoplasmosis 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
453 Toxoplasmosis 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
454 Transcriptional misregulation in cancer 💬
 [1] CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
455 Tuberculosis 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
456 Tuberculosis 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
457 Tuberculosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
458 Tuberculosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
459 Tuberculosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
460 Tuberculosis 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
461 Tuberculosis 💬
 [1] VDR 💬 D00188 💬 Cholecalciferol [23]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 162, 202, 228, 271, 298, 299 💬
462 Type I diabetes mellitus 💬
 [2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
463 Type I diabetes mellitus 💬
 [2] LTA, TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
464 Type II diabetes mellitus 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
465 Type II diabetes mellitus 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
466 VEGF signaling pathway 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
467 VEGF signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
468 VEGF signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
469 VEGF signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
470 Viral carcinogenesis 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
471 Viral myocarditis 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
472 Viral myocarditis 💬
 [2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
473 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] IL2RA 💬 D03639 💬 Daclizumab [7] 13, 56, 60, 65, 97, 283, 284 💬
474 Viral protein interaction with cytokine and cytokine receptor 💬
 [2] LTA, TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
475 Wnt signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
476 Wnt signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
477 Wnt signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [32]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
478 Yersinia infection 💬
 [1] TNF 💬 D00742 💬 Etanercept [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬

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