Target Gene/Pathway💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
1 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
PGR [1] PGR 💬 |
D00952 D00952 💬 |
Megestrol acetate | 076 [1] 76 💬 |
2 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
PGR [1] PGR 💬 |
D08167 D08167 💬 |
Megestrol acetate | 076 [1] 76 💬 |
3 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [20] 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
4 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
PGR [1] PGR 💬 |
D00952 D00952 💬 |
Megestrol acetate | 076 [1] 76 💬 |
5 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
PGR [1] PGR 💬 |
D08167 D08167 💬 |
Megestrol acetate | 076 [1] 76 💬 |
6 | GnRH signaling pathway 💬 15 genes, 33 drugs (DrugBank) and 38 diseases |
GNRHR [1] GNRHR 💬 |
D00988 D00988 💬 |
Gonadorelin | 076 [1] 76 💬 |
7 | GnRH signaling pathway 💬 15 genes, 33 drugs (DrugBank) and 38 diseases |
GNRHR [1] GNRHR 💬 |
D03267 D03267 💬 |
Gonadorelin | 076 [1] 76 💬 |
8 | GnRH signaling pathway 💬 15 genes, 33 drugs (DrugBank) and 38 diseases |
GNRHR [1] GNRHR 💬 |
D04361 D04361 💬 |
Gonadorelin | 076 [1] 76 💬 |
9 | GnRH signaling pathway 💬 15 genes, 33 drugs (DrugBank) and 38 diseases |
GNRHR [1] GNRHR 💬 |
D08027 D08027 💬 |
Gonadorelin | 076 [1] 76 💬 |
10 | GnRH signaling pathway 💬 15 genes, 33 drugs (DrugBank) and 38 diseases |
GNRHR [1] GNRHR 💬 |
D02369 D02369 💬 |
Histrelin | 076 [1] 76 💬 |
11 | GnRH signaling pathway 💬 15 genes, 33 drugs (DrugBank) and 38 diseases |
GNRHR [1] GNRHR 💬 |
D00989 D00989 💬 |
Leuprolide | 001 [5] 1 , 2 , 3 , 51, 76 💬 |
12 | GnRH signaling pathway 💬 15 genes, 33 drugs (DrugBank) and 38 diseases |
GNRHR [1] GNRHR 💬 |
D06247 D06247 💬 |
Triptorelin | 049 [2] 49, 76 💬 |
13 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [20] 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
14 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [20] 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
15 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [20] 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
16 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GNRHR [1] GNRHR 💬 |
D00988 D00988 💬 |
Gonadorelin | 076 [1] 76 💬 |
17 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GNRHR [1] GNRHR 💬 |
D03267 D03267 💬 |
Gonadorelin | 076 [1] 76 💬 |
18 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GNRHR [1] GNRHR 💬 |
D04361 D04361 💬 |
Gonadorelin | 076 [1] 76 💬 |
19 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GNRHR [1] GNRHR 💬 |
D08027 D08027 💬 |
Gonadorelin | 076 [1] 76 💬 |
20 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GNRHR [1] GNRHR 💬 |
D02369 D02369 💬 |
Histrelin | 076 [1] 76 💬 |
21 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GNRHR [1] GNRHR 💬 |
D00989 D00989 💬 |
Leuprolide | 001 [5] 1 , 2 , 3 , 51, 76 💬 |
22 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GNRHR [1] GNRHR 💬 |
D06247 D06247 💬 |
Triptorelin | 049 [2] 49, 76 💬 |
23 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
PGR [1] PGR 💬 |
D00952 D00952 💬 |
Megestrol acetate | 076 [1] 76 💬 |
24 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
PGR [1] PGR 💬 |
D08167 D08167 💬 |
Megestrol acetate | 076 [1] 76 💬 |
25 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [20] 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
26 | Progesterone-mediated oocyte maturation 💬 14 genes, 32 drugs (DrugBank) and 37 diseases |
PGR [1] PGR 💬 |
D00952 D00952 💬 |
Megestrol acetate | 076 [1] 76 💬 |
27 | Progesterone-mediated oocyte maturation 💬 14 genes, 32 drugs (DrugBank) and 37 diseases |
PGR [1] PGR 💬 |
D08167 D08167 💬 |
Megestrol acetate | 076 [1] 76 💬 |