Target Gene/Pathway💬 Info on mouse-over

15 / 286 pathways

No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adipocytokine signaling pathway 💬
[1] PPARA 💬 D00565 💬 Fenofibrate [5]  8 , 79, 93, 94, 265 💬
2 AMPK signaling pathway 💬
[1] HMGCR 💬 D00887 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
3 AMPK signaling pathway 💬
[1] HMGCR 💬 D07474 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
4 AMPK signaling pathway 💬
[1] HMGCR 💬 D00892 💬 Fluvastatin [3] 79, 218, 222 💬
5 AMPK signaling pathway 💬
[1] HMGCR 💬 D07983 💬 Fluvastatin [3] 79, 218, 222 💬
6 AMPK signaling pathway 💬
[1] HMGCR 💬 D00359 💬 Lovastatin [11]  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
7 AMPK signaling pathway 💬
[1] HMGCR 💬 D00893 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
8 AMPK signaling pathway 💬
[1] HMGCR 💬 D08410 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
9 AMPK signaling pathway 💬
[1] HMGCR 💬 D01915 💬 Rosuvastatin [11]  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
10 AMPK signaling pathway 💬
[1] HMGCR 💬 D08492 💬 Rosuvastatin [11]  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
11 AMPK signaling pathway 💬
[1] HMGCR 💬 D00434 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
12 Bile secretion 💬
[1] HMGCR 💬 D00887 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
13 Bile secretion 💬
[1] HMGCR 💬 D07474 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
14 Bile secretion 💬
[1] HMGCR 💬 D00892 💬 Fluvastatin [3] 79, 218, 222 💬
15 Bile secretion 💬
[1] HMGCR 💬 D07983 💬 Fluvastatin [3] 79, 218, 222 💬
16 Bile secretion 💬
[1] HMGCR 💬 D00359 💬 Lovastatin [11]  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
17 Bile secretion 💬
[1] HMGCR 💬 D00893 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
18 Bile secretion 💬
[1] HMGCR 💬 D08410 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
19 Bile secretion 💬
[1] HMGCR 💬 D01915 💬 Rosuvastatin [11]  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
20 Bile secretion 💬
[1] HMGCR 💬 D08492 💬 Rosuvastatin [11]  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
21 Bile secretion 💬
[1] HMGCR 💬 D00434 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
22 cAMP signaling pathway 💬
[1] PPARA 💬 D00565 💬 Fenofibrate [5]  8 , 79, 93, 94, 265 💬
23 Cholesterol metabolism 💬
[1] ANGPTL3 💬 D11753 💬 Evinacumab [1] 79 💬
24 Cholesterol metabolism 💬
[1] CETP 💬 D08855 💬 Anacetrapib [1] 79 💬
25 Cholesterol metabolism 💬
[1] PCSK9 💬 D10335 💬 Alirocumab [1] 79 💬
26 Cholesterol metabolism 💬
[1] PCSK9 💬 D10557 💬 Evolocumab [2] 79, 222 💬
27 Cholesterol metabolism 💬
[1] PCSK9 💬 D11931 💬 Inclisiran [1] 79 💬
28 Complement and coagulation cascades 💬
[1] SERPINC1 💬 D07510 💬 Heparin [11] 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317 💬
29 Diabetic cardiomyopathy 💬
[1] PPARA 💬 D00565 💬 Fenofibrate [5]  8 , 79, 93, 94, 265 💬
30 Fat digestion and absorption 💬
[1] MTTP 💬 D09637 💬 Lomitapide [1] 79 💬
31 Fat digestion and absorption 💬
[1] NPC1L1 💬 D01966 💬 Ezetimibe [4] 49, 79, 93, 260 💬
32 Glucagon signaling pathway 💬
[1] PPARA 💬 D00565 💬 Fenofibrate [5]  8 , 79, 93, 94, 265 💬
33 Hepatitis C 💬
[1] PPARA 💬 D00565 💬 Fenofibrate [5]  8 , 79, 93, 94, 265 💬
34 Insulin resistance 💬
[1] PPARA 💬 D00565 💬 Fenofibrate [5]  8 , 79, 93, 94, 265 💬
35 Metabolic pathways 💬
[1] HMGCR 💬 D00887 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
36 Metabolic pathways 💬
[1] HMGCR 💬 D07474 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
37 Metabolic pathways 💬
[1] HMGCR 💬 D00892 💬 Fluvastatin [3] 79, 218, 222 💬
38 Metabolic pathways 💬
[1] HMGCR 💬 D07983 💬 Fluvastatin [3] 79, 218, 222 💬
39 Metabolic pathways 💬
[1] HMGCR 💬 D00359 💬 Lovastatin [11]  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
40 Metabolic pathways 💬
[1] HMGCR 💬 D00893 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
41 Metabolic pathways 💬
[1] HMGCR 💬 D08410 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
42 Metabolic pathways 💬
[1] HMGCR 💬 D01915 💬 Rosuvastatin [11]  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
43 Metabolic pathways 💬
[1] HMGCR 💬 D08492 💬 Rosuvastatin [11]  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
44 Metabolic pathways 💬
[1] HMGCR 💬 D00434 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
45 Non-alcoholic fatty liver disease 💬
[1] PPARA 💬 D00565 💬 Fenofibrate [5]  8 , 79, 93, 94, 265 💬
46 PPAR signaling pathway 💬
[1] PPARA 💬 D00565 💬 Fenofibrate [5]  8 , 79, 93, 94, 265 💬
47 Terpenoid backbone biosynthesis 💬
[1] HMGCR 💬 D00887 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
48 Terpenoid backbone biosynthesis 💬
[1] HMGCR 💬 D07474 💬 Atorvastatin [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
49 Terpenoid backbone biosynthesis 💬
[1] HMGCR 💬 D00892 💬 Fluvastatin [3] 79, 218, 222 💬
50 Terpenoid backbone biosynthesis 💬
[1] HMGCR 💬 D07983 💬 Fluvastatin [3] 79, 218, 222 💬
51 Terpenoid backbone biosynthesis 💬
[1] HMGCR 💬 D00359 💬 Lovastatin [11]  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
52 Terpenoid backbone biosynthesis 💬
[1] HMGCR 💬 D00893 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
53 Terpenoid backbone biosynthesis 💬
[1] HMGCR 💬 D08410 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
54 Terpenoid backbone biosynthesis 💬
[1] HMGCR 💬 D01915 💬 Rosuvastatin [11]  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
55 Terpenoid backbone biosynthesis 💬
[1] HMGCR 💬 D08492 💬 Rosuvastatin [11]  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
56 Terpenoid backbone biosynthesis 💬
[1] HMGCR 💬 D00434 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬