Target Gene/Pathway💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
1 | Acute myeloid leukemia 💬 15 genes, 25 drugs (DrugBank) and 59 diseases |
BRAF [4] BRAF, FLT3, KIT, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
2 | Acute myeloid leukemia 💬 15 genes, 25 drugs (DrugBank) and 59 diseases |
BRAF [4] BRAF, FLT3, KIT, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
3 | Acute myeloid leukemia 💬 15 genes, 25 drugs (DrugBank) and 59 diseases |
KIT [1] KIT 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
4 | Acute myeloid leukemia 💬 15 genes, 25 drugs (DrugBank) and 59 diseases |
KIT [1] KIT 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
5 | Acute myeloid leukemia 💬 15 genes, 25 drugs (DrugBank) and 59 diseases |
KIT [1] KIT 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
6 | Acute myeloid leukemia 💬 15 genes, 25 drugs (DrugBank) and 59 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
7 | Adherens junction 💬 9 genes, 18 drugs (DrugBank) and 24 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
8 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
9 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
10 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
11 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D00255 D00255 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
12 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D03415 D03415 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
13 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
ADRB1 [1] ADRB1 💬 |
D00634 D00634 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
14 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
ADRB1 [1] ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
15 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
ADRB2 [1] ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 [14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬 |
16 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
AGTR1 [2] AGTR1, AGTR2 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
17 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
AGTR1 [2] AGTR1, AGTR2 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
18 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
19 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
20 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
21 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
22 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
23 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
SCN5A [1] SCN5A 💬 |
D00358 D00358 💬 |
Lidocaine | 006 [12] 6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬 |
24 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
SCN5A [1] SCN5A 💬 |
D02086 D02086 💬 |
Lidocaine | 006 [12] 6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬 |
25 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
SCN5A [1] SCN5A 💬 |
D08127 D08127 💬 |
Lidocaine | 006 [12] 6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬 |
26 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
AGTR1 [1] AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
27 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
AGTR1 [1] AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
28 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
29 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
30 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
31 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
D01462 D01462 💬 |
Lisuride | 006 [2] 6 , 86 💬 |
32 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
D08132 D08132 💬 |
Lisuride | 006 [2] 6 , 86 💬 |
33 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬 |
D01348 D01348 💬 |
Terguride | 051 [2] 51, 86 💬 |
34 | Aldosterone synthesis and secretion 💬 18 genes, 34 drugs (DrugBank) and 64 diseases |
AGTR1 [1] AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
35 | Aldosterone synthesis and secretion 💬 18 genes, 34 drugs (DrugBank) and 64 diseases |
AGTR1 [1] AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
36 | Aldosterone synthesis and secretion 💬 18 genes, 34 drugs (DrugBank) and 64 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
37 | Aldosterone synthesis and secretion 💬 18 genes, 34 drugs (DrugBank) and 64 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
38 | Aldosterone synthesis and secretion 💬 18 genes, 34 drugs (DrugBank) and 64 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
39 | Aldosterone synthesis and secretion 💬 18 genes, 34 drugs (DrugBank) and 64 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
40 | Aldosterone synthesis and secretion 💬 18 genes, 34 drugs (DrugBank) and 64 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
41 | Aldosterone synthesis and secretion 💬 18 genes, 34 drugs (DrugBank) and 64 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
42 | Aldosterone synthesis and secretion 💬 18 genes, 34 drugs (DrugBank) and 64 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
43 | Aldosterone-regulated sodium reabsorption 💬 12 genes, 12 drugs (DrugBank) and 23 diseases |
NR3C2 [1] NR3C2 💬 |
D00443 D00443 💬 |
Spironolactone | 058 [7] 58, 67, 86, 113, 210, 218, 225 💬 |
44 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
45 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
46 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
47 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
48 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
49 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
50 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
51 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D02212 D02212 💬 |
Ipratropium | 006 [2] 6 , 86 💬 |
52 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
53 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
54 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
55 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
56 | Amoebiasis 💬 17 genes, 25 drugs (DrugBank) and 62 diseases |
IL1R1 [2] IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
57 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
58 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
59 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
60 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
61 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
62 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
ADRA1A [1] ADRA1A 💬 |
D00255 D00255 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
63 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
ADRA1A [1] ADRA1A 💬 |
D03415 D03415 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
64 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
HMGCR [1] HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
65 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
66 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
67 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
68 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
69 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
70 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
71 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
72 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
AGTR1 [1] AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
73 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
AGTR1 [1] AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
74 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
75 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
76 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
77 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
78 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
79 | Apoptosis 💬 14 genes, 23 drugs (DrugBank) and 54 diseases |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
80 | Apoptosis 💬 14 genes, 23 drugs (DrugBank) and 54 diseases |
PARP1 [2] PARP1, PARP2 💬 |
D09730 D09730 💬 |
Olaparib | 086 [2] 86, 285 💬 |
81 | Apoptosis 💬 14 genes, 23 drugs (DrugBank) and 54 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
82 | Apoptosis 💬 14 genes, 23 drugs (DrugBank) and 54 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
83 | Arachidonic acid metabolism 💬 4 genes, 25 drugs (DrugBank) and 38 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
84 | Arachidonic acid metabolism 💬 4 genes, 25 drugs (DrugBank) and 38 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
85 | Arrhythmogenic right ventricular cardiomyopathy 💬 11 genes, 24 drugs (DrugBank) and 28 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
86 | Arrhythmogenic right ventricular cardiomyopathy 💬 11 genes, 24 drugs (DrugBank) and 28 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
87 | Arrhythmogenic right ventricular cardiomyopathy 💬 11 genes, 24 drugs (DrugBank) and 28 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
88 | Arrhythmogenic right ventricular cardiomyopathy 💬 11 genes, 24 drugs (DrugBank) and 28 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
89 | Arrhythmogenic right ventricular cardiomyopathy 💬 11 genes, 24 drugs (DrugBank) and 28 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
90 | Autophagy - animal 💬 13 genes, 15 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
91 | Autophagy - animal 💬 13 genes, 15 drugs (DrugBank) and 57 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
92 | Autophagy - animal 💬 13 genes, 15 drugs (DrugBank) and 57 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
93 | Autophagy - animal 💬 13 genes, 15 drugs (DrugBank) and 57 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
94 | Autophagy - animal 💬 13 genes, 15 drugs (DrugBank) and 57 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
95 | Autophagy - other 💬 1 gene, 3 drugs (DrugBank) and 41 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
96 | Axon guidance 💬 21 genes, 19 drugs (DrugBank) and 65 diseases |
ABL1 [1] ABL1 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
97 | Axon guidance 💬 21 genes, 19 drugs (DrugBank) and 65 diseases |
ABL1 [1] ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
98 | Axon guidance 💬 21 genes, 19 drugs (DrugBank) and 65 diseases |
ABL1 [1] ABL1 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
99 | Axon guidance 💬 21 genes, 19 drugs (DrugBank) and 65 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
100 | Axon guidance 💬 21 genes, 19 drugs (DrugBank) and 65 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
101 | B cell receptor signaling pathway 💬 16 genes, 19 drugs (DrugBank) and 63 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
102 | B cell receptor signaling pathway 💬 16 genes, 19 drugs (DrugBank) and 63 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
103 | Base excision repair 💬 2 genes, 1 drug (DrugBank) and 2 diseases |
PARP1 [2] PARP1, PARP2 💬 |
D09730 D09730 💬 |
Olaparib | 086 [2] 86, 285 💬 |
104 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
CA2 [1] CA2 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
105 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
CA2 [1] CA2 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
106 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
HMGCR [1] HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
107 | Bladder cancer 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
108 | Bladder cancer 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
109 | Bladder cancer 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
110 | Bladder cancer 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
111 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
BRAF [4] BRAF, FLT4, KIT, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
112 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
BRAF [4] BRAF, FLT4, KIT, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
113 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
114 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D01161 D01161 💬 |
Fulvestrant | 049 [2] 49, 86 💬 |
115 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
116 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D00966 D00966 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
117 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
118 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
KIT [1] KIT 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
119 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
KIT [1] KIT 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
120 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
KIT [1] KIT 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
121 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
122 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
123 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
124 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
125 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
126 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D00255 D00255 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
127 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D03415 D03415 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
128 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADRB1 [1] ADRB1 💬 |
D00634 D00634 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
129 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADRB1 [1] ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
130 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADRB2 [1] ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 [14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬 |
131 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
AGTR1 [1] AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
132 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
AGTR1 [1] AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
133 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
AVPR1A [1] AVPR1A 💬 |
D01236 D01236 💬 |
Conivaptan | 086 [1] 86 💬 |
134 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
AVPR1A [1] AVPR1A 💬 |
D07748 D07748 💬 |
Conivaptan | 086 [1] 86 💬 |
135 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
136 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
137 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
138 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
139 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
140 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
141 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
142 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
D02212 D02212 💬 |
Ipratropium | 006 [2] 6 , 86 💬 |
143 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
EDNRA [1] EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬 |
144 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
EDNRA [1] EDNRA 💬 |
D07171 D07171 💬 |
Sitaxentan | 086 [1] 86 💬 |
145 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
146 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
147 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
D10135 D10135 💬 |
Macitentan | 051 [5] 51, 85, 86, 88, 210 💬 |
148 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
149 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
FLT4 [4] FLT4, KDR, PDGFRB, RET 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
150 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
FLT4 [4] FLT4, KDR, PDGFRB, RET 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
151 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
HRH1 [1] HRH1 💬 |
D00300 D00300 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
152 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
HRH1 [1] HRH1 💬 |
D00669 D00669 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
153 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
HRH1 [1] HRH1 💬 |
D02419 D02419 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
154 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
HRH1 [1] HRH1 💬 |
D03285 D03285 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
155 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
HRH1 [1] HRH1 💬 |
D03360 D03360 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
156 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
HRH1 [1] HRH1 💬 |
D03854 D03854 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
157 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
HRH2 [1] HRH2 💬 |
D00318 D00318 💬 |
Famotidine | 006 [4] 6 , 46, 86, 98 💬 |
158 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
PDGFRA [1] PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
159 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
PDGFRA [1] PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
160 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
161 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
TBXA2R [1] TBXA2R 💬 |
D04500 D04500 💬 |
Ifetroban | 051 [3] 51, 86, 113 💬 |
162 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
163 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
ADRB1 [1] ADRB1 💬 |
D00634 D00634 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
164 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
ADRB1 [1] ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
165 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00255 D00255 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
166 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
D03415 D03415 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
167 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
ADRB2 [1] ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 [14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬 |
168 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
169 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
170 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
171 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
172 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
173 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
174 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
175 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
D02212 D02212 💬 |
Ipratropium | 006 [2] 6 , 86 💬 |
176 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
DRD2 [1] DRD2 💬 |
D01462 D01462 💬 |
Lisuride | 006 [2] 6 , 86 💬 |
177 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
DRD2 [1] DRD2 💬 |
D08132 D08132 💬 |
Lisuride | 006 [2] 6 , 86 💬 |
178 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
DRD2 [1] DRD2 💬 |
D01348 D01348 💬 |
Terguride | 051 [2] 51, 86 💬 |
179 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
EDNRA [1] EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬 |
180 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
EDNRA [1] EDNRA 💬 |
D01227 D01227 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
181 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
EDNRA [1] EDNRA 💬 |
D07538 D07538 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
182 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
EDNRA [1] EDNRA 💬 |
D10135 D10135 💬 |
Macitentan | 051 [5] 51, 85, 86, 88, 210 💬 |
183 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
EDNRA [1] EDNRA 💬 |
D07171 D07171 💬 |
Sitaxentan | 086 [1] 86 💬 |
184 | Carbohydrate digestion and absorption 💬 10 genes, 16 drugs (DrugBank) and 28 diseases |
CACNA1D [1] CACNA1D 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
185 | Carbohydrate digestion and absorption 💬 10 genes, 16 drugs (DrugBank) and 28 diseases |
CACNA1D [1] CACNA1D 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
186 | Carbohydrate digestion and absorption 💬 10 genes, 16 drugs (DrugBank) and 28 diseases |
CACNA1D [1] CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
187 | Carbohydrate digestion and absorption 💬 10 genes, 16 drugs (DrugBank) and 28 diseases |
CACNA1D [1] CACNA1D 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
188 | Carbohydrate digestion and absorption 💬 10 genes, 16 drugs (DrugBank) and 28 diseases |
CACNA1D [1] CACNA1D 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
189 | Carbohydrate digestion and absorption 💬 10 genes, 16 drugs (DrugBank) and 28 diseases |
TAS1R2 [2] TAS1R2, TAS1R3 💬 |
D02381 D02381 💬 |
Aspartame | 006 [5] 6 , 13, 67, 86, 230 💬 |
190 | Cardiac muscle contraction 💬 12 genes, 16 drugs (DrugBank) and 25 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
191 | Cardiac muscle contraction 💬 12 genes, 16 drugs (DrugBank) and 25 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
192 | Cardiac muscle contraction 💬 12 genes, 16 drugs (DrugBank) and 25 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
193 | Cardiac muscle contraction 💬 12 genes, 16 drugs (DrugBank) and 25 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
194 | Cardiac muscle contraction 💬 12 genes, 16 drugs (DrugBank) and 25 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
195 | Cell cycle 💬 7 genes, 8 drugs (DrugBank) and 23 diseases |
ABL1 [1] ABL1 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
196 | Cell cycle 💬 7 genes, 8 drugs (DrugBank) and 23 diseases |
ABL1 [1] ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
197 | Cell cycle 💬 7 genes, 8 drugs (DrugBank) and 23 diseases |
ABL1 [1] ABL1 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
198 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
CACNA1D [1] CACNA1D 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
199 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
CACNA1D [1] CACNA1D 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
200 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
CACNA1D [1] CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
201 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
CACNA1D [1] CACNA1D 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
202 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
CACNA1D [1] CACNA1D 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
203 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
204 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
205 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
206 | Central carbon metabolism in cancer 💬 18 genes, 24 drugs (DrugBank) and 55 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
207 | Central carbon metabolism in cancer 💬 18 genes, 24 drugs (DrugBank) and 55 diseases |
FLT3 [5] FLT3, KIT, PDGFRB, RAF1, RET 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
208 | Central carbon metabolism in cancer 💬 18 genes, 24 drugs (DrugBank) and 55 diseases |
FLT3 [5] FLT3, KIT, PDGFRB, RAF1, RET 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
209 | Central carbon metabolism in cancer 💬 18 genes, 24 drugs (DrugBank) and 55 diseases |
KIT [2] KIT, PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
210 | Central carbon metabolism in cancer 💬 18 genes, 24 drugs (DrugBank) and 55 diseases |
KIT [2] KIT, PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
211 | Central carbon metabolism in cancer 💬 18 genes, 24 drugs (DrugBank) and 55 diseases |
KIT [3] KIT, PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
212 | Central carbon metabolism in cancer 💬 18 genes, 24 drugs (DrugBank) and 55 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
213 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D00255 D00255 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
214 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D03415 D03415 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
215 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRB1 [1] ADRB1 💬 |
D00634 D00634 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
216 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRB1 [1] ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
217 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRB2 [1] ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 [14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬 |
218 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
AGTR1 [1] AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
219 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
AGTR1 [1] AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
220 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
221 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
222 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
223 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
224 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
225 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
EDNRA [1] EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬 |
226 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
EDNRA [1] EDNRA 💬 |
D07171 D07171 💬 |
Sitaxentan | 086 [1] 86 💬 |
227 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
228 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
229 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
D10135 D10135 💬 |
Macitentan | 051 [5] 51, 85, 86, 88, 210 💬 |
230 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬 |
231 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PDE5A [1] PDE5A 💬 |
D02229 D02229 💬 |
Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
232 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PDE5A [1] PDE5A 💬 |
D08514 D08514 💬 |
Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
233 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PDE5A [1] PDE5A 💬 |
D02008 D02008 💬 |
Tadalafil | 006 [7] 6 , 51, 75, 84, 86, 113, 210 💬 |
234 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PDE5A [1] PDE5A 💬 |
D10027 D10027 💬 |
Udenafil | 086 [2] 86, 210 💬 |
235 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PDE5A [1] PDE5A 💬 |
D02731 D02731 💬 |
Vardenafil | 013 [3] 13, 86, 299 💬 |
236 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PDE5A [1] PDE5A 💬 |
D03260 D03260 💬 |
Vardenafil | 013 [3] 13, 86, 299 💬 |
237 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PDE5A [1] PDE5A 💬 |
D08668 D08668 💬 |
Vardenafil | 013 [3] 13, 86, 299 💬 |
238 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
239 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
240 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
ACE [1] ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 [8] 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
241 | Chemical carcinogenesis 💬 5 genes, 26 drugs (DrugBank) and 37 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
242 | Chemical carcinogenesis 💬 5 genes, 26 drugs (DrugBank) and 37 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
243 | Chemokine signaling pathway 💬 20 genes, 23 drugs (DrugBank) and 41 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
244 | Chemokine signaling pathway 💬 20 genes, 23 drugs (DrugBank) and 41 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
245 | Choline metabolism in cancer 💬 10 genes, 20 drugs (DrugBank) and 51 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
246 | Choline metabolism in cancer 💬 10 genes, 20 drugs (DrugBank) and 51 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
247 | Choline metabolism in cancer 💬 10 genes, 20 drugs (DrugBank) and 51 diseases |
PDGFRA [1] PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
248 | Choline metabolism in cancer 💬 10 genes, 20 drugs (DrugBank) and 51 diseases |
PDGFRA [1] PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
249 | Choline metabolism in cancer 💬 10 genes, 20 drugs (DrugBank) and 51 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
250 | Choline metabolism in cancer 💬 10 genes, 20 drugs (DrugBank) and 51 diseases |
PDGFRB [2] PDGFRB, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
251 | Choline metabolism in cancer 💬 10 genes, 20 drugs (DrugBank) and 51 diseases |
PDGFRB [2] PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
252 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
253 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
254 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
255 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
256 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
257 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D02212 D02212 💬 |
Ipratropium | 006 [2] 6 , 86 💬 |
258 | Chronic myeloid leukemia 💬 14 genes, 15 drugs (DrugBank) and 28 diseases |
ABL1 [1] ABL1 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
259 | Chronic myeloid leukemia 💬 14 genes, 15 drugs (DrugBank) and 28 diseases |
ABL1 [1] ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
260 | Chronic myeloid leukemia 💬 14 genes, 15 drugs (DrugBank) and 28 diseases |
ABL1 [1] ABL1 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
261 | Chronic myeloid leukemia 💬 14 genes, 15 drugs (DrugBank) and 28 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
262 | Chronic myeloid leukemia 💬 14 genes, 15 drugs (DrugBank) and 28 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
263 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
264 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
265 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
266 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
267 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
268 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
269 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
270 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬 |
271 | Circadian rhythm 💬 2 genes, 1 drug (DrugBank) and 21 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
272 | Circadian rhythm 💬 2 genes, 1 drug (DrugBank) and 21 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
273 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
DRD2 [1] DRD2 💬 |
D01462 D01462 💬 |
Lisuride | 006 [2] 6 , 86 💬 |
274 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
DRD2 [1] DRD2 💬 |
D08132 D08132 💬 |
Lisuride | 006 [2] 6 , 86 💬 |
275 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
DRD2 [1] DRD2 💬 |
D01348 D01348 💬 |
Terguride | 051 [2] 51, 86 💬 |
276 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D01984 D01984 💬 |
Esomeprazole | 013 [6] 13, 46, 86, 98, 298, 299 💬 |
277 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D04056 D04056 💬 |
Esomeprazole | 013 [6] 13, 46, 86, 98, 298, 299 💬 |
278 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D07917 D07917 💬 |
Esomeprazole | 013 [6] 13, 46, 86, 98, 298, 299 💬 |
279 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D09339 D09339 💬 |
Esomeprazole | 013 [6] 13, 46, 86, 98, 298, 299 💬 |
280 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
CA2 [1] CA2 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
281 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
CA2 [1] CA2 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
282 | Colorectal cancer 💬 14 genes, 19 drugs (DrugBank) and 49 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
283 | Colorectal cancer 💬 14 genes, 19 drugs (DrugBank) and 49 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
284 | Colorectal cancer 💬 14 genes, 19 drugs (DrugBank) and 49 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
285 | Colorectal cancer 💬 14 genes, 19 drugs (DrugBank) and 49 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
286 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
ACE [1] ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 [8] 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
287 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
AGTR1 [1] AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
288 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
AGTR1 [1] AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
289 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
290 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
291 | Cortisol synthesis and secretion 💬 14 genes, 30 drugs (DrugBank) and 62 diseases |
AGTR1 [1] AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
292 | Cortisol synthesis and secretion 💬 14 genes, 30 drugs (DrugBank) and 62 diseases |
AGTR1 [1] AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
293 | Cortisol synthesis and secretion 💬 14 genes, 30 drugs (DrugBank) and 62 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
294 | Cortisol synthesis and secretion 💬 14 genes, 30 drugs (DrugBank) and 62 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
295 | Cortisol synthesis and secretion 💬 14 genes, 30 drugs (DrugBank) and 62 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
296 | Cortisol synthesis and secretion 💬 14 genes, 30 drugs (DrugBank) and 62 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
297 | Cortisol synthesis and secretion 💬 14 genes, 30 drugs (DrugBank) and 62 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
298 | Cortisol synthesis and secretion 💬 14 genes, 30 drugs (DrugBank) and 62 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
299 | Cortisol synthesis and secretion 💬 14 genes, 30 drugs (DrugBank) and 62 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
300 | Cushing syndrome 💬 21 genes, 43 drugs (DrugBank) and 66 diseases |
AGTR1 [1] AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
301 | Cushing syndrome 💬 21 genes, 43 drugs (DrugBank) and 66 diseases |
AGTR1 [1] AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
302 | Cushing syndrome 💬 21 genes, 43 drugs (DrugBank) and 66 diseases |
BRAF [1] BRAF 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
303 | Cushing syndrome 💬 21 genes, 43 drugs (DrugBank) and 66 diseases |
BRAF [1] BRAF 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
304 | Cushing syndrome 💬 21 genes, 43 drugs (DrugBank) and 66 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
305 | Cushing syndrome 💬 21 genes, 43 drugs (DrugBank) and 66 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
306 | Cushing syndrome 💬 21 genes, 43 drugs (DrugBank) and 66 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
307 | Cushing syndrome 💬 21 genes, 43 drugs (DrugBank) and 66 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
308 | Cushing syndrome 💬 21 genes, 43 drugs (DrugBank) and 66 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
309 | Cushing syndrome 💬 21 genes, 43 drugs (DrugBank) and 66 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
310 | Cushing syndrome 💬 21 genes, 43 drugs (DrugBank) and 66 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
311 | Cushing syndrome 💬 21 genes, 43 drugs (DrugBank) and 66 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
312 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
ACVR2A [1] ACVR2A 💬 |
D09670 D09670 💬 |
Sotatercept | 086 [2] 86, 284 💬 |
313 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IL1R1 [2] IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
314 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
315 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
PRL [1] PRL 💬 |
D01348 D01348 💬 |
Terguride | 051 [2] 51, 86 💬 |
316 | Diabetic cardiomyopathy 💬 21 genes, 38 drugs (DrugBank) and 72 diseases |
ACE [1] ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 [8] 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
317 | Diabetic cardiomyopathy 💬 21 genes, 38 drugs (DrugBank) and 72 diseases |
AGTR1 [1] AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
318 | Diabetic cardiomyopathy 💬 21 genes, 38 drugs (DrugBank) and 72 diseases |
AGTR1 [1] AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
319 | Diabetic cardiomyopathy 💬 21 genes, 38 drugs (DrugBank) and 72 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
320 | Diabetic cardiomyopathy 💬 21 genes, 38 drugs (DrugBank) and 72 diseases |
PARP1 [1] PARP1 💬 |
D09730 D09730 💬 |
Olaparib | 086 [2] 86, 285 💬 |
321 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
ADRB1 [1] ADRB1 💬 |
D00634 D00634 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
322 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
ADRB1 [1] ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
323 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
ADRB1 [1] ADRB1 💬 |
D00255 D00255 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
324 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
ADRB1 [1] ADRB1 💬 |
D03415 D03415 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
325 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
326 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
327 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
328 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
329 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
330 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
331 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
332 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
333 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
334 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
335 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
DRD2 [1] DRD2 💬 |
D01348 D01348 💬 |
Terguride | 051 [2] 51, 86 💬 |
336 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
DRD2 [3] DRD2, DRD3, DRD4 💬 |
D01462 D01462 💬 |
Lisuride | 006 [2] 6 , 86 💬 |
337 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
DRD2 [3] DRD2, DRD3, DRD4 💬 |
D08132 D08132 💬 |
Lisuride | 006 [2] 6 , 86 💬 |
338 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
SCN1A [1] SCN1A 💬 |
D00358 D00358 💬 |
Lidocaine | 006 [12] 6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬 |
339 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
SCN1A [1] SCN1A 💬 |
D02086 D02086 💬 |
Lidocaine | 006 [12] 6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬 |
340 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
SCN1A [1] SCN1A 💬 |
D08127 D08127 💬 |
Lidocaine | 006 [12] 6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬 |
341 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 46 diseases |
RRM2 [1] RRM2 💬 |
D00341 D00341 💬 |
Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬 |
342 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
BRAF [4] BRAF, KDR, PDGFRB, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
343 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
BRAF [4] BRAF, KDR, PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
344 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
345 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
346 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
347 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
PDGFRA [1] PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
348 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
PDGFRA [1] PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
349 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
350 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
351 | Endocrine and other factor-regulated calcium reabsorption 💬 7 genes, 25 drugs (DrugBank) and 49 diseases |
ESR1 [1] ESR1 💬 |
D01161 D01161 💬 |
Fulvestrant | 049 [2] 49, 86 💬 |
352 | Endocrine and other factor-regulated calcium reabsorption 💬 7 genes, 25 drugs (DrugBank) and 49 diseases |
ESR1 [1] ESR1 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
353 | Endocrine and other factor-regulated calcium reabsorption 💬 7 genes, 25 drugs (DrugBank) and 49 diseases |
ESR1 [1] ESR1 💬 |
D00966 D00966 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
354 | Endocrine and other factor-regulated calcium reabsorption 💬 7 genes, 25 drugs (DrugBank) and 49 diseases |
ESR1 [1] ESR1 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
355 | Endocrine resistance 💬 19 genes, 37 drugs (DrugBank) and 59 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
356 | Endocrine resistance 💬 19 genes, 37 drugs (DrugBank) and 59 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
357 | Endocrine resistance 💬 19 genes, 37 drugs (DrugBank) and 59 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
358 | Endocrine resistance 💬 19 genes, 37 drugs (DrugBank) and 59 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D01161 D01161 💬 |
Fulvestrant | 049 [2] 49, 86 💬 |
359 | Endocrine resistance 💬 19 genes, 37 drugs (DrugBank) and 59 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
360 | Endocrine resistance 💬 19 genes, 37 drugs (DrugBank) and 59 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D00966 D00966 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
361 | Endocrine resistance 💬 19 genes, 37 drugs (DrugBank) and 59 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
362 | Endocrine resistance 💬 19 genes, 37 drugs (DrugBank) and 59 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
363 | Endocytosis 💬 20 genes, 27 drugs (DrugBank) and 50 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
364 | Endocytosis 💬 20 genes, 27 drugs (DrugBank) and 50 diseases |
PDGFRA [1] PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
365 | Endocytosis 💬 20 genes, 27 drugs (DrugBank) and 50 diseases |
PDGFRA [1] PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
366 | Endocytosis 💬 20 genes, 27 drugs (DrugBank) and 50 diseases |
PDGFRA [1] PDGFRA 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
367 | Endometrial cancer 💬 10 genes, 14 drugs (DrugBank) and 21 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
368 | Endometrial cancer 💬 10 genes, 14 drugs (DrugBank) and 21 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
369 | Endometrial cancer 💬 10 genes, 14 drugs (DrugBank) and 21 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
370 | Epithelial cell signaling in Helicobacter pylori infection 💬 11 genes, 15 drugs (DrugBank) and 21 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
371 | ErbB signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 51 diseases |
ABL1 [1] ABL1 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
372 | ErbB signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 51 diseases |
ABL1 [1] ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
373 | ErbB signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 51 diseases |
ABL1 [1] ABL1 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
374 | ErbB signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 51 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
375 | ErbB signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 51 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
376 | ErbB signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 51 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
377 | ErbB signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 51 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
378 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
379 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D01161 D01161 💬 |
Fulvestrant | 049 [2] 49, 86 💬 |
380 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
381 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D00966 D00966 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
382 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
383 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
OPRM1 [1] OPRM1 💬 |
D00842 D00842 💬 |
Morphine | 036 [5] 36, 46, 70, 85, 86 💬 |
384 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
OPRM1 [1] OPRM1 💬 |
D02271 D02271 💬 |
Morphine | 036 [5] 36, 46, 70, 85, 86 💬 |
385 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
OPRM1 [1] OPRM1 💬 |
D08233 D08233 💬 |
Morphine | 036 [5] 36, 46, 70, 85, 86 💬 |
386 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
387 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
388 | Fc epsilon RI signaling pathway 💬 19 genes, 35 drugs (DrugBank) and 59 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
389 | Fc epsilon RI signaling pathway 💬 19 genes, 35 drugs (DrugBank) and 59 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
390 | Fc gamma R-mediated phagocytosis 💬 8 genes, 8 drugs (DrugBank) and 13 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
391 | Fc gamma R-mediated phagocytosis 💬 8 genes, 8 drugs (DrugBank) and 13 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
392 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
ACVR2A [1] ACVR2A 💬 |
D09670 D09670 💬 |
Sotatercept | 086 [2] 86, 284 💬 |
393 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
IL1R1 [2] IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
394 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
KDR [1] KDR 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
395 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
KDR [1] KDR 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
396 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
KEAP1 [1] KEAP1 💬 |
D03846 D03846 💬 |
Dimethyl fumarate | 013 [4] 13, 51, 86, 296 💬 |
397 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
398 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
399 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
400 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
401 | Focal adhesion 💬 26 genes, 37 drugs (DrugBank) and 42 diseases |
BRAF [5] BRAF, FLT4, KDR, PDGFRB, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
402 | Focal adhesion 💬 26 genes, 37 drugs (DrugBank) and 42 diseases |
BRAF [5] BRAF, FLT4, KDR, PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
403 | Focal adhesion 💬 26 genes, 37 drugs (DrugBank) and 42 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
404 | Focal adhesion 💬 26 genes, 37 drugs (DrugBank) and 42 diseases |
PDGFRA [1] PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
405 | Focal adhesion 💬 26 genes, 37 drugs (DrugBank) and 42 diseases |
PDGFRA [1] PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
406 | Focal adhesion 💬 26 genes, 37 drugs (DrugBank) and 42 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
407 | Focal adhesion 💬 26 genes, 37 drugs (DrugBank) and 42 diseases |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
408 | FoxO signaling pathway 💬 24 genes, 34 drugs (DrugBank) and 53 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
409 | FoxO signaling pathway 💬 24 genes, 34 drugs (DrugBank) and 53 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
410 | FoxO signaling pathway 💬 24 genes, 34 drugs (DrugBank) and 53 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
411 | FoxO signaling pathway 💬 24 genes, 34 drugs (DrugBank) and 53 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
412 | FoxO signaling pathway 💬 24 genes, 34 drugs (DrugBank) and 53 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
413 | GABAergic synapse 💬 28 genes, 37 drugs (DrugBank) and 54 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
414 | GABAergic synapse 💬 28 genes, 37 drugs (DrugBank) and 54 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
415 | GABAergic synapse 💬 28 genes, 37 drugs (DrugBank) and 54 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
416 | GABAergic synapse 💬 28 genes, 37 drugs (DrugBank) and 54 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
417 | GABAergic synapse 💬 28 genes, 37 drugs (DrugBank) and 54 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
418 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
ADRB1 [1] ADRB1 💬 |
D00634 D00634 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
419 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
ADRB1 [1] ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
420 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
ADRB1 [1] ADRB1 💬 |
D00255 D00255 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
421 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
ADRB1 [1] ADRB1 💬 |
D03415 D03415 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
422 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
DRD2 [1] DRD2 💬 |
D01462 D01462 💬 |
Lisuride | 006 [2] 6 , 86 💬 |
423 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
DRD2 [1] DRD2 💬 |
D08132 D08132 💬 |
Lisuride | 006 [2] 6 , 86 💬 |
424 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
DRD2 [1] DRD2 💬 |
D01348 D01348 💬 |
Terguride | 051 [2] 51, 86 💬 |
425 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
426 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬 |
427 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
PDGFRA [1] PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
428 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
PDGFRA [1] PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
429 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
430 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
PDGFRB [2] PDGFRB, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
431 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
PDGFRB [2] PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
432 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D01984 D01984 💬 |
Esomeprazole | 013 [6] 13, 46, 86, 98, 298, 299 💬 |
433 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D04056 D04056 💬 |
Esomeprazole | 013 [6] 13, 46, 86, 98, 298, 299 💬 |
434 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D07917 D07917 💬 |
Esomeprazole | 013 [6] 13, 46, 86, 98, 298, 299 💬 |
435 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D09339 D09339 💬 |
Esomeprazole | 013 [6] 13, 46, 86, 98, 298, 299 💬 |
436 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
CA2 [1] CA2 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
437 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
CA2 [1] CA2 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
438 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
CHRM3 [1] CHRM3 💬 |
D02212 D02212 💬 |
Ipratropium | 006 [2] 6 , 86 💬 |
439 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
HRH2 [1] HRH2 💬 |
D00318 D00318 💬 |
Famotidine | 006 [4] 6 , 46, 86, 98 💬 |
440 | Gastric cancer 💬 20 genes, 29 drugs (DrugBank) and 57 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
441 | Gastric cancer 💬 20 genes, 29 drugs (DrugBank) and 57 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
442 | Gastric cancer 💬 20 genes, 29 drugs (DrugBank) and 57 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
443 | Gastric cancer 💬 20 genes, 29 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
444 | Glioma 💬 12 genes, 24 drugs (DrugBank) and 56 diseases |
BRAF [3] BRAF, PDGFRB, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
445 | Glioma 💬 12 genes, 24 drugs (DrugBank) and 56 diseases |
BRAF [3] BRAF, PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
446 | Glioma 💬 12 genes, 24 drugs (DrugBank) and 56 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
447 | Glioma 💬 12 genes, 24 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
448 | Glioma 💬 12 genes, 24 drugs (DrugBank) and 56 diseases |
PDGFRA [1] PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
449 | Glioma 💬 12 genes, 24 drugs (DrugBank) and 56 diseases |
PDGFRA [1] PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
450 | Glioma 💬 12 genes, 24 drugs (DrugBank) and 56 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
451 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
452 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
453 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
454 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
455 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
456 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
457 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
458 | Glutathione metabolism 💬 4 genes, 6 drugs (DrugBank) and 24 diseases |
ANPEP [1] ANPEP 💬 |
D00087 D00087 💬 |
Ubenimex | 086 [1] 86 💬 |
459 | Glutathione metabolism 💬 4 genes, 6 drugs (DrugBank) and 24 diseases |
RRM2 [1] RRM2 💬 |
D00341 D00341 💬 |
Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬 |
460 | GnRH secretion 💬 19 genes, 36 drugs (DrugBank) and 53 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
461 | GnRH secretion 💬 19 genes, 36 drugs (DrugBank) and 53 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
462 | GnRH secretion 💬 19 genes, 36 drugs (DrugBank) and 53 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
463 | GnRH secretion 💬 19 genes, 36 drugs (DrugBank) and 53 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
464 | GnRH secretion 💬 19 genes, 36 drugs (DrugBank) and 53 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
465 | GnRH secretion 💬 19 genes, 36 drugs (DrugBank) and 53 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
466 | GnRH secretion 💬 19 genes, 36 drugs (DrugBank) and 53 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
467 | GnRH secretion 💬 19 genes, 36 drugs (DrugBank) and 53 diseases |
ESR2 [1] ESR2 💬 |
D01161 D01161 💬 |
Fulvestrant | 049 [2] 49, 86 💬 |
468 | GnRH secretion 💬 19 genes, 36 drugs (DrugBank) and 53 diseases |
ESR2 [1] ESR2 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
469 | GnRH secretion 💬 19 genes, 36 drugs (DrugBank) and 53 diseases |
ESR2 [1] ESR2 💬 |
D00966 D00966 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
470 | GnRH secretion 💬 19 genes, 36 drugs (DrugBank) and 53 diseases |
ESR2 [1] ESR2 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
471 | GnRH secretion 💬 19 genes, 36 drugs (DrugBank) and 53 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
472 | GnRH secretion 💬 19 genes, 36 drugs (DrugBank) and 53 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
473 | GnRH signaling pathway 💬 15 genes, 33 drugs (DrugBank) and 38 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
474 | GnRH signaling pathway 💬 15 genes, 33 drugs (DrugBank) and 38 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
475 | GnRH signaling pathway 💬 15 genes, 33 drugs (DrugBank) and 38 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
476 | GnRH signaling pathway 💬 15 genes, 33 drugs (DrugBank) and 38 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
477 | GnRH signaling pathway 💬 15 genes, 33 drugs (DrugBank) and 38 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
478 | GnRH signaling pathway 💬 15 genes, 33 drugs (DrugBank) and 38 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
479 | GnRH signaling pathway 💬 15 genes, 33 drugs (DrugBank) and 38 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
480 | GnRH signaling pathway 💬 15 genes, 33 drugs (DrugBank) and 38 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
481 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
482 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
483 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
484 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
485 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
486 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
487 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
488 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
489 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
ANPEP [1] ANPEP 💬 |
D00087 D00087 💬 |
Ubenimex | 086 [1] 86 💬 |
490 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
FLT3 [2] FLT3, KIT 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
491 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
FLT3 [2] FLT3, KIT 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
492 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
IL1R1 [2] IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
493 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
494 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
KIT [1] KIT 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
495 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
KIT [1] KIT 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
496 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
KIT [1] KIT 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
497 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
MS4A1 [1] MS4A1 💬 |
D02994 D02994 💬 |
Rituximab | 011 [47] 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬 |
498 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
499 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
500 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
501 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
502 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
503 | Hepatocellular carcinoma 💬 18 genes, 25 drugs (DrugBank) and 57 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
504 | Hepatocellular carcinoma 💬 18 genes, 25 drugs (DrugBank) and 57 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
505 | Hepatocellular carcinoma 💬 18 genes, 25 drugs (DrugBank) and 57 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
506 | Hepatocellular carcinoma 💬 18 genes, 25 drugs (DrugBank) and 57 diseases |
KEAP1 [1] KEAP1 💬 |
D03846 D03846 💬 |
Dimethyl fumarate | 013 [4] 13, 51, 86, 296 💬 |
507 | Hepatocellular carcinoma 💬 18 genes, 25 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
508 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
509 | HIF-1 signaling pathway 💬 20 genes, 40 drugs (DrugBank) and 73 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
510 | HIF-1 signaling pathway 💬 20 genes, 40 drugs (DrugBank) and 73 diseases |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
511 | HIF-1 signaling pathway 💬 20 genes, 40 drugs (DrugBank) and 73 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
512 | HIF-1 signaling pathway 💬 20 genes, 40 drugs (DrugBank) and 73 diseases |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
513 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
514 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
515 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
516 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
517 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
PDGFRA [1] PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
518 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
PDGFRA [1] PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
519 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
PDGFRA [1] PDGFRA 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
520 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
521 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
522 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
523 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
524 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
525 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
526 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
527 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
528 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
529 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
530 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
PDGFRB [1] PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
531 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
PDGFRB [2] PDGFRB, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
532 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
PDGFRB [2] PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
533 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
534 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
535 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
536 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
IL1R1 [2] IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
537 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
538 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
539 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
540 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
541 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
ACE [1] ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 [8] 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
542 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
543 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
544 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
545 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
546 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
547 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
548 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
549 | IL-17 signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
550 | IL-17 signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
551 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
HRH1 [1] HRH1 💬 |
D00300 D00300 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
552 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
HRH1 [1] HRH1 💬 |
D00669 D00669 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
553 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
HRH1 [1] HRH1 💬 |
D02419 D02419 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
554 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
HRH1 [1] HRH1 💬 |
D03285 D03285 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
555 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
HRH1 [1] HRH1 💬 |
D03360 D03360 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
556 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
HRH1 [1] HRH1 💬 |
D03854 D03854 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
557 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
558 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
TRPV1 [1] TRPV1 💬 |
D00250 D00250 💬 |
Capsaicin | 002 [5] 2 , 6 , 19, 86, 226 💬 |
559 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
560 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
561 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
562 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
563 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
564 | Insulin secretion 💬 13 genes, 40 drugs (DrugBank) and 43 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
565 | Insulin secretion 💬 13 genes, 40 drugs (DrugBank) and 43 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
566 | Insulin secretion 💬 13 genes, 40 drugs (DrugBank) and 43 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
567 | Insulin secretion 💬 13 genes, 40 drugs (DrugBank) and 43 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
568 | Insulin secretion 💬 13 genes, 40 drugs (DrugBank) and 43 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
569 | Insulin secretion 💬 13 genes, 40 drugs (DrugBank) and 43 diseases |
CHRM3 [1] CHRM3 💬 |
D02212 D02212 💬 |
Ipratropium | 006 [2] 6 , 86 💬 |
570 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
571 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
572 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
573 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
574 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
575 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
576 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
577 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
578 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
PDGFRA [1] PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
579 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
PDGFRA [1] PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
580 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
581 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
PDGFRB [2] PDGFRB, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
582 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
PDGFRB [2] PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
583 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
PRL [1] PRL 💬 |
D01348 D01348 💬 |
Terguride | 051 [2] 51, 86 💬 |
584 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
585 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
586 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
587 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
588 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
589 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
590 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
591 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
592 | Long-term depression 💬 12 genes, 15 drugs (DrugBank) and 29 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
593 | Long-term depression 💬 12 genes, 15 drugs (DrugBank) and 29 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
594 | Long-term depression 💬 12 genes, 15 drugs (DrugBank) and 29 diseases |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬 |
595 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
596 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
597 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
CACNA1C [1] CACNA1C 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
598 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
CACNA1C [1] CACNA1C 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
599 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
CACNA1C [1] CACNA1C 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
600 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
CACNA1C [1] CACNA1C 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
601 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
CACNA1C [1] CACNA1C 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
602 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
603 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
604 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
605 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
606 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
607 | Longevity regulating pathway - multiple species 💬 10 genes, 13 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
608 | Longevity regulating pathway - multiple species 💬 10 genes, 13 drugs (DrugBank) and 56 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
609 | Longevity regulating pathway - multiple species 💬 10 genes, 13 drugs (DrugBank) and 56 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
610 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
BRAF [7] BRAF, FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
611 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
BRAF [7] BRAF, FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
612 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
613 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
614 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
615 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
616 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
617 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
618 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
619 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
620 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
621 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
KIT [2] KIT, PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
622 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
KIT [2] KIT, PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
623 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
KIT [3] KIT, PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
624 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
625 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
626 | Melanogenesis 💬 5 genes, 11 drugs (DrugBank) and 25 diseases |
EDNRB [1] EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
627 | Melanogenesis 💬 5 genes, 11 drugs (DrugBank) and 25 diseases |
EDNRB [1] EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
628 | Melanogenesis 💬 5 genes, 11 drugs (DrugBank) and 25 diseases |
EDNRB [1] EDNRB 💬 |
D10135 D10135 💬 |
Macitentan | 051 [5] 51, 85, 86, 88, 210 💬 |
629 | Melanogenesis 💬 5 genes, 11 drugs (DrugBank) and 25 diseases |
KIT [1] KIT 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
630 | Melanogenesis 💬 5 genes, 11 drugs (DrugBank) and 25 diseases |
KIT [1] KIT 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
631 | Melanogenesis 💬 5 genes, 11 drugs (DrugBank) and 25 diseases |
KIT [1] KIT 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
632 | Melanogenesis 💬 5 genes, 11 drugs (DrugBank) and 25 diseases |
KIT [2] KIT, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
633 | Melanogenesis 💬 5 genes, 11 drugs (DrugBank) and 25 diseases |
KIT [2] KIT, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
634 | Melanoma 💬 13 genes, 23 drugs (DrugBank) and 34 diseases |
BRAF [3] BRAF, PDGFRB, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
635 | Melanoma 💬 13 genes, 23 drugs (DrugBank) and 34 diseases |
BRAF [3] BRAF, PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
636 | Melanoma 💬 13 genes, 23 drugs (DrugBank) and 34 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
637 | Melanoma 💬 13 genes, 23 drugs (DrugBank) and 34 diseases |
PDGFRA [1] PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
638 | Melanoma 💬 13 genes, 23 drugs (DrugBank) and 34 diseases |
PDGFRA [1] PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
639 | Melanoma 💬 13 genes, 23 drugs (DrugBank) and 34 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
640 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
ANPEP [1] ANPEP 💬 |
D00087 D00087 💬 |
Ubenimex | 086 [1] 86 💬 |
641 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D01984 D01984 💬 |
Esomeprazole | 013 [6] 13, 46, 86, 98, 298, 299 💬 |
642 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D04056 D04056 💬 |
Esomeprazole | 013 [6] 13, 46, 86, 98, 298, 299 💬 |
643 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D07917 D07917 💬 |
Esomeprazole | 013 [6] 13, 46, 86, 98, 298, 299 💬 |
644 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D09339 D09339 💬 |
Esomeprazole | 013 [6] 13, 46, 86, 98, 298, 299 💬 |
645 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
646 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
647 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
CYP19A1 [1] CYP19A1 💬 |
D00960 D00960 💬 |
Anastrozole | 078 [3] 78, 86, 193 💬 |
648 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬 |
649 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
HMGCR [1] HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
650 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PDE5A [1] PDE5A 💬 |
D02229 D02229 💬 |
Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
651 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PDE5A [1] PDE5A 💬 |
D08514 D08514 💬 |
Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
652 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PDE5A [1] PDE5A 💬 |
D02008 D02008 💬 |
Tadalafil | 006 [7] 6 , 51, 75, 84, 86, 113, 210 💬 |
653 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PDE5A [1] PDE5A 💬 |
D10027 D10027 💬 |
Udenafil | 086 [2] 86, 210 💬 |
654 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PDE5A [1] PDE5A 💬 |
D02731 D02731 💬 |
Vardenafil | 013 [3] 13, 86, 299 💬 |
655 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PDE5A [1] PDE5A 💬 |
D03260 D03260 💬 |
Vardenafil | 013 [3] 13, 86, 299 💬 |
656 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PDE5A [1] PDE5A 💬 |
D08668 D08668 💬 |
Vardenafil | 013 [3] 13, 86, 299 💬 |
657 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
658 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
659 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
RRM2 [1] RRM2 💬 |
D00341 D00341 💬 |
Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬 |
660 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
ABL1 [2] ABL1, PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
661 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
ABL1 [2] ABL1, PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
662 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
ABL1 [3] ABL1, PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
663 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
664 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
665 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
PDGFRB [2] PDGFRB, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
666 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
PDGFRB [2] PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
667 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
668 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
669 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
670 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
OPRM1 [1] OPRM1 💬 |
D00842 D00842 💬 |
Morphine | 036 [5] 36, 46, 70, 85, 86 💬 |
671 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
OPRM1 [1] OPRM1 💬 |
D02271 D02271 💬 |
Morphine | 036 [5] 36, 46, 70, 85, 86 💬 |
672 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
OPRM1 [1] OPRM1 💬 |
D08233 D08233 💬 |
Morphine | 036 [5] 36, 46, 70, 85, 86 💬 |
673 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
674 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
675 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
676 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
677 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
678 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
679 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
680 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
PARP1 [1] PARP1 💬 |
D09730 D09730 💬 |
Olaparib | 086 [2] 86, 285 💬 |
681 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D00255 D00255 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
682 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D03415 D03415 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
683 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRB1 [1] ADRB1 💬 |
D00634 D00634 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
684 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRB1 [1] ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
685 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRB2 [1] ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 [14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬 |
686 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
AGTR1 [2] AGTR1, AGTR2 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
687 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
AGTR1 [2] AGTR1, AGTR2 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
688 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
AVPR1A [2] AVPR1A, AVPR2 💬 |
D01236 D01236 💬 |
Conivaptan | 086 [1] 86 💬 |
689 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
AVPR1A [2] AVPR1A, AVPR2 💬 |
D07748 D07748 💬 |
Conivaptan | 086 [1] 86 💬 |
690 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D02212 D02212 💬 |
Ipratropium | 006 [2] 6 , 86 💬 |
691 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
DRD2 [3] DRD2, DRD3, DRD4 💬 |
D01462 D01462 💬 |
Lisuride | 006 [2] 6 , 86 💬 |
692 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
DRD2 [3] DRD2, DRD3, DRD4 💬 |
D08132 D08132 💬 |
Lisuride | 006 [2] 6 , 86 💬 |
693 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
DRD2 [2] DRD2, PRL 💬 |
D01348 D01348 💬 |
Terguride | 051 [2] 51, 86 💬 |
694 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
EDNRA [1] EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬 |
695 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
EDNRA [1] EDNRA 💬 |
D07171 D07171 💬 |
Sitaxentan | 086 [1] 86 💬 |
696 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
697 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
698 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
D10135 D10135 💬 |
Macitentan | 051 [5] 51, 85, 86, 88, 210 💬 |
699 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
HRH1 [1] HRH1 💬 |
D00300 D00300 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
700 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
HRH1 [1] HRH1 💬 |
D00669 D00669 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
701 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
HRH1 [1] HRH1 💬 |
D02419 D02419 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
702 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
HRH1 [1] HRH1 💬 |
D03285 D03285 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
703 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
HRH1 [1] HRH1 💬 |
D03360 D03360 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
704 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
HRH1 [1] HRH1 💬 |
D03854 D03854 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
705 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
HRH2 [1] HRH2 💬 |
D00318 D00318 💬 |
Famotidine | 006 [4] 6 , 46, 86, 98 💬 |
706 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00407 D00407 💬 |
Methylprednisolone | 002 [44] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
707 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00751 D00751 💬 |
Methylprednisolone | 002 [44] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
708 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00979 D00979 💬 |
Methylprednisolone | 002 [44] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
709 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D05000 D05000 💬 |
Methylprednisolone | 002 [44] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
710 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D05001 D05001 💬 |
Methylprednisolone | 002 [44] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
711 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D05002 D05002 💬 |
Methylprednisolone | 002 [44] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
712 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00473 D00473 💬 |
Prednisone | 002 [47] 2 , 6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 93, 95, 96, 97, 113, 127, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬 |
713 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
OPRM1 [1] OPRM1 💬 |
D00842 D00842 💬 |
Morphine | 036 [5] 36, 46, 70, 85, 86 💬 |
714 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
OPRM1 [1] OPRM1 💬 |
D02271 D02271 💬 |
Morphine | 036 [5] 36, 46, 70, 85, 86 💬 |
715 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
OPRM1 [1] OPRM1 💬 |
D08233 D08233 💬 |
Morphine | 036 [5] 36, 46, 70, 85, 86 💬 |
716 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
PTGIR [1] PTGIR 💬 |
D02720 D02720 💬 |
Beraprost | 086 [1] 86 💬 |
717 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
PTGIR [1] PTGIR 💬 |
D00106 D00106 💬 |
Epoprostenol | 086 [1] 86 💬 |
718 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
PTGIR [1] PTGIR 💬 |
D01337 D01337 💬 |
Epoprostenol | 086 [1] 86 💬 |
719 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
PTGIR [1] PTGIR 💬 |
D02721 D02721 💬 |
Iloprost | 051 [4] 51, 84, 85, 86 💬 |
720 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
PTGIR [1] PTGIR 💬 |
D10725 D10725 💬 |
Ralinepag | 086 [1] 86 💬 |
721 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
PTGIR [1] PTGIR 💬 |
D09994 D09994 💬 |
Selexipag | 051 [5] 51, 70, 84, 86, 88 💬 |
722 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
PTGIR [1] PTGIR 💬 |
D06213 D06213 💬 |
Treprostinil | 051 [6] 51, 84, 85, 86, 88, 210 💬 |
723 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
TBXA2R [1] TBXA2R 💬 |
D04500 D04500 💬 |
Ifetroban | 051 [3] 51, 86, 113 💬 |
724 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
TRPV1 [1] TRPV1 💬 |
D00250 D00250 💬 |
Capsaicin | 002 [5] 2 , 6 , 19, 86, 226 💬 |
725 | Neurotrophin signaling pathway 💬 19 genes, 21 drugs (DrugBank) and 29 diseases |
ABL1 [1] ABL1 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
726 | Neurotrophin signaling pathway 💬 19 genes, 21 drugs (DrugBank) and 29 diseases |
ABL1 [1] ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
727 | Neurotrophin signaling pathway 💬 19 genes, 21 drugs (DrugBank) and 29 diseases |
ABL1 [1] ABL1 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
728 | Neurotrophin signaling pathway 💬 19 genes, 21 drugs (DrugBank) and 29 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
729 | Neurotrophin signaling pathway 💬 19 genes, 21 drugs (DrugBank) and 29 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
730 | Neurotrophin signaling pathway 💬 19 genes, 21 drugs (DrugBank) and 29 diseases |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
731 | Neutrophil extracellular trap formation 💬 32 genes, 27 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
732 | Neutrophil extracellular trap formation 💬 32 genes, 27 drugs (DrugBank) and 56 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
733 | Neutrophil extracellular trap formation 💬 32 genes, 27 drugs (DrugBank) and 56 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
734 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
735 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
PARP1 [1] PARP1 💬 |
D09730 D09730 💬 |
Olaparib | 086 [2] 86, 285 💬 |
736 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
737 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
738 | Nitrogen metabolism 💬 14 genes, 5 drugs (DrugBank) and 16 diseases |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
739 | Nitrogen metabolism 💬 14 genes, 5 drugs (DrugBank) and 16 diseases |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
740 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
741 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
742 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
743 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
744 | Non-small cell lung cancer 💬 18 genes, 27 drugs (DrugBank) and 42 diseases |
BRAF [3] BRAF, RAF1, RET 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
745 | Non-small cell lung cancer 💬 18 genes, 27 drugs (DrugBank) and 42 diseases |
BRAF [3] BRAF, RAF1, RET 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
746 | Non-small cell lung cancer 💬 18 genes, 27 drugs (DrugBank) and 42 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
747 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
AR [1] AR 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
748 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
749 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
750 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
751 | Ovarian steroidogenesis 💬 6 genes, 34 drugs (DrugBank) and 47 diseases |
CYP19A1 [1] CYP19A1 💬 |
D00960 D00960 💬 |
Anastrozole | 078 [3] 78, 86, 193 💬 |
752 | Ovarian steroidogenesis 💬 6 genes, 34 drugs (DrugBank) and 47 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
753 | Ovarian steroidogenesis 💬 6 genes, 34 drugs (DrugBank) and 47 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
754 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 23 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D01984 D01984 💬 |
Esomeprazole | 013 [6] 13, 46, 86, 98, 298, 299 💬 |
755 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 23 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D04056 D04056 💬 |
Esomeprazole | 013 [6] 13, 46, 86, 98, 298, 299 💬 |
756 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 23 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D07917 D07917 💬 |
Esomeprazole | 013 [6] 13, 46, 86, 98, 298, 299 💬 |
757 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 23 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D09339 D09339 💬 |
Esomeprazole | 013 [6] 13, 46, 86, 98, 298, 299 💬 |
758 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
759 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
760 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
761 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
762 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
763 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
764 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬 |
765 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
766 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
767 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
768 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
769 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
770 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
771 | p53 signaling pathway 💬 3 genes, 3 drugs (DrugBank) and 12 diseases |
RRM2 [1] RRM2 💬 |
D00341 D00341 💬 |
Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬 |
772 | Pancreatic cancer 💬 16 genes, 29 drugs (DrugBank) and 64 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
773 | Pancreatic cancer 💬 16 genes, 29 drugs (DrugBank) and 64 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
774 | Pancreatic cancer 💬 16 genes, 29 drugs (DrugBank) and 64 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
775 | Pancreatic cancer 💬 16 genes, 29 drugs (DrugBank) and 64 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
776 | Pancreatic cancer 💬 16 genes, 29 drugs (DrugBank) and 64 diseases |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
777 | Pancreatic secretion 💬 10 genes, 34 drugs (DrugBank) and 33 diseases |
CA2 [1] CA2 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
778 | Pancreatic secretion 💬 10 genes, 34 drugs (DrugBank) and 33 diseases |
CA2 [1] CA2 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
779 | Pancreatic secretion 💬 10 genes, 34 drugs (DrugBank) and 33 diseases |
CHRM3 [1] CHRM3 💬 |
D02212 D02212 💬 |
Ipratropium | 006 [2] 6 , 86 💬 |
780 | Parathyroid hormone synthesis, secretion and action 💬 19 genes, 40 drugs (DrugBank) and 58 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
781 | Parathyroid hormone synthesis, secretion and action 💬 19 genes, 40 drugs (DrugBank) and 58 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
782 | Parathyroid hormone synthesis, secretion and action 💬 19 genes, 40 drugs (DrugBank) and 58 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
783 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
DRD2 [1] DRD2 💬 |
D01462 D01462 💬 |
Lisuride | 006 [2] 6 , 86 💬 |
784 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
DRD2 [1] DRD2 💬 |
D08132 D08132 💬 |
Lisuride | 006 [2] 6 , 86 💬 |
785 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
DRD2 [1] DRD2 💬 |
D01348 D01348 💬 |
Terguride | 051 [2] 51, 86 💬 |
786 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
787 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
ABL1 [1] ABL1 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
788 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
ABL1 [1] ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
789 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
ABL1 [1] ABL1 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
790 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
791 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
ABL1 [3] ABL1, KIT, PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
792 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
ABL1 [3] ABL1, KIT, PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
793 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
ABL1 [4] ABL1, KIT, PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
794 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
AGTR1 [1] AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
795 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
AGTR1 [1] AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
796 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
AR [3] AR, ESR1, ESR2 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
797 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
BRAF [7] BRAF, FLT3, FLT4, KIT, PDGFRB, RAF1, RET 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
798 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
BRAF [7] BRAF, FLT3, FLT4, KIT, PDGFRB, RAF1, RET 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
799 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
EDNRA [1] EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬 |
800 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
EDNRA [1] EDNRA 💬 |
D07171 D07171 💬 |
Sitaxentan | 086 [1] 86 💬 |
801 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
802 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
803 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
EDNRA [2] EDNRA, EDNRB 💬 |
D10135 D10135 💬 |
Macitentan | 051 [5] 51, 85, 86, 88, 210 💬 |
804 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
805 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D01161 D01161 💬 |
Fulvestrant | 049 [2] 49, 86 💬 |
806 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D00966 D00966 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
807 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
808 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
809 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
KEAP1 [1] KEAP1 💬 |
D03846 D03846 💬 |
Dimethyl fumarate | 013 [4] 13, 51, 86, 296 💬 |
810 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
811 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
812 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
813 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
814 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
815 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
816 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
817 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
818 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
819 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
820 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
821 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
822 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
823 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
CHRM1 [3] CHRM1, CHRM3, CHRM5 💬 |
D02212 D02212 💬 |
Ipratropium | 006 [2] 6 , 86 💬 |
824 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
825 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
826 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
827 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
828 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
829 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
830 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
831 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
832 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
AGTR1 [1] AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
833 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
AGTR1 [1] AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
834 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
AVPR1A [2] AVPR1A, AVPR2 💬 |
D01236 D01236 💬 |
Conivaptan | 086 [1] 86 💬 |
835 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
AVPR1A [2] AVPR1A, AVPR2 💬 |
D07748 D07748 💬 |
Conivaptan | 086 [1] 86 💬 |
836 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
837 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
KIT [2] KIT, PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
838 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
KIT [2] KIT, PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
839 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
KIT [3] KIT, PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
840 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
KIT [3] KIT, PDGFRB, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
841 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
KIT [3] KIT, PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
842 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
843 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
CHRM1 [2] CHRM1, CHRM2 💬 |
D02212 D02212 💬 |
Ipratropium | 006 [2] 6 , 86 💬 |
844 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
845 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
FLT3 [6] FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
846 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
FLT3 [6] FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
847 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
848 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
KIT [2] KIT, PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
849 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
KIT [2] KIT, PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
850 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
KIT [3] KIT, PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
851 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
852 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
853 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
854 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
PRL [1] PRL 💬 |
D01348 D01348 💬 |
Terguride | 051 [2] 51, 86 💬 |
855 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
856 | Platelet activation 💬 22 genes, 44 drugs (DrugBank) and 47 diseases |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬 |
857 | Platelet activation 💬 22 genes, 44 drugs (DrugBank) and 47 diseases |
P2RY12 [1] P2RY12 💬 |
D00769 D00769 💬 |
Clopidogrel | 049 [2] 49, 86 💬 |
858 | Platelet activation 💬 22 genes, 44 drugs (DrugBank) and 47 diseases |
P2RY12 [1] P2RY12 💬 |
D07729 D07729 💬 |
Clopidogrel | 049 [2] 49, 86 💬 |
859 | Platelet activation 💬 22 genes, 44 drugs (DrugBank) and 47 diseases |
P2RY12 [1] P2RY12 💬 |
D10823 D10823 💬 |
Clopidogrel | 049 [2] 49, 86 💬 |
860 | Platelet activation 💬 22 genes, 44 drugs (DrugBank) and 47 diseases |
P2RY12 [1] P2RY12 💬 |
D10824 D10824 💬 |
Clopidogrel | 049 [2] 49, 86 💬 |
861 | Platelet activation 💬 22 genes, 44 drugs (DrugBank) and 47 diseases |
PTGIR [1] PTGIR 💬 |
D02720 D02720 💬 |
Beraprost | 086 [1] 86 💬 |
862 | Platelet activation 💬 22 genes, 44 drugs (DrugBank) and 47 diseases |
PTGIR [1] PTGIR 💬 |
D00106 D00106 💬 |
Epoprostenol | 086 [1] 86 💬 |
863 | Platelet activation 💬 22 genes, 44 drugs (DrugBank) and 47 diseases |
PTGIR [1] PTGIR 💬 |
D01337 D01337 💬 |
Epoprostenol | 086 [1] 86 💬 |
864 | Platelet activation 💬 22 genes, 44 drugs (DrugBank) and 47 diseases |
PTGIR [1] PTGIR 💬 |
D02721 D02721 💬 |
Iloprost | 051 [4] 51, 84, 85, 86 💬 |
865 | Platelet activation 💬 22 genes, 44 drugs (DrugBank) and 47 diseases |
PTGIR [1] PTGIR 💬 |
D10725 D10725 💬 |
Ralinepag | 086 [1] 86 💬 |
866 | Platelet activation 💬 22 genes, 44 drugs (DrugBank) and 47 diseases |
PTGIR [1] PTGIR 💬 |
D09994 D09994 💬 |
Selexipag | 051 [5] 51, 70, 84, 86, 88 💬 |
867 | Platelet activation 💬 22 genes, 44 drugs (DrugBank) and 47 diseases |
PTGIR [1] PTGIR 💬 |
D06213 D06213 💬 |
Treprostinil | 051 [6] 51, 84, 85, 86, 88, 210 💬 |
868 | Platelet activation 💬 22 genes, 44 drugs (DrugBank) and 47 diseases |
PTGS1 [1] PTGS1 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
869 | Platelet activation 💬 22 genes, 44 drugs (DrugBank) and 47 diseases |
PTGS1 [1] PTGS1 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
870 | Platelet activation 💬 22 genes, 44 drugs (DrugBank) and 47 diseases |
TBXA2R [1] TBXA2R 💬 |
D04500 D04500 💬 |
Ifetroban | 051 [3] 51, 86, 113 💬 |
871 | Platinum drug resistance 💬 9 genes, 12 drugs (DrugBank) and 22 diseases |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
872 | PPAR signaling pathway 💬 10 genes, 12 drugs (DrugBank) and 30 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
873 | PPAR signaling pathway 💬 10 genes, 12 drugs (DrugBank) and 30 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
874 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
875 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
876 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
877 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
878 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
879 | Progesterone-mediated oocyte maturation 💬 14 genes, 32 drugs (DrugBank) and 37 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
880 | Progesterone-mediated oocyte maturation 💬 14 genes, 32 drugs (DrugBank) and 37 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
881 | Prolactin signaling pathway 💬 18 genes, 33 drugs (DrugBank) and 48 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D01161 D01161 💬 |
Fulvestrant | 049 [2] 49, 86 💬 |
882 | Prolactin signaling pathway 💬 18 genes, 33 drugs (DrugBank) and 48 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
883 | Prolactin signaling pathway 💬 18 genes, 33 drugs (DrugBank) and 48 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D00966 D00966 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
884 | Prolactin signaling pathway 💬 18 genes, 33 drugs (DrugBank) and 48 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
885 | Prolactin signaling pathway 💬 18 genes, 33 drugs (DrugBank) and 48 diseases |
PRL [1] PRL 💬 |
D01348 D01348 💬 |
Terguride | 051 [2] 51, 86 💬 |
886 | Prolactin signaling pathway 💬 18 genes, 33 drugs (DrugBank) and 48 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
887 | Prolactin signaling pathway 💬 18 genes, 33 drugs (DrugBank) and 48 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
888 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
AR [1] AR 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
889 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
BRAF [3] BRAF, PDGFRB, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
890 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
BRAF [3] BRAF, PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
891 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
892 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
IL1R2 [1] IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
893 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
894 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
PDGFRA [1] PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
895 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
PDGFRA [1] PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
896 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
897 | Protein processing in endoplasmic reticulum 💬 3 genes, 3 drugs (DrugBank) and 3 diseases |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
898 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
BRAF [3] BRAF, KDR, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
899 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
BRAF [3] BRAF, KDR, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
900 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
901 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
ESR1 [1] ESR1 💬 |
D01161 D01161 💬 |
Fulvestrant | 049 [2] 49, 86 💬 |
902 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
ESR1 [1] ESR1 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
903 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
ESR1 [1] ESR1 💬 |
D00966 D00966 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
904 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
ESR1 [1] ESR1 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
905 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
906 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
907 | Proximal tubule bicarbonate reclamation 💬 6 genes, 6 drugs (DrugBank) and 17 diseases |
CA2 [2] CA2, CA4 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
908 | Proximal tubule bicarbonate reclamation 💬 6 genes, 6 drugs (DrugBank) and 17 diseases |
CA2 [2] CA2, CA4 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
909 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬 |
910 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
PDE5A [1] PDE5A 💬 |
D02229 D02229 💬 |
Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
911 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
PDE5A [1] PDE5A 💬 |
D08514 D08514 💬 |
Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
912 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
PDE5A [1] PDE5A 💬 |
D02008 D02008 💬 |
Tadalafil | 006 [7] 6 , 51, 75, 84, 86, 113, 210 💬 |
913 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
PDE5A [1] PDE5A 💬 |
D10027 D10027 💬 |
Udenafil | 086 [2] 86, 210 💬 |
914 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
PDE5A [1] PDE5A 💬 |
D02731 D02731 💬 |
Vardenafil | 013 [3] 13, 86, 299 💬 |
915 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
PDE5A [1] PDE5A 💬 |
D03260 D03260 💬 |
Vardenafil | 013 [3] 13, 86, 299 💬 |
916 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
PDE5A [1] PDE5A 💬 |
D08668 D08668 💬 |
Vardenafil | 013 [3] 13, 86, 299 💬 |
917 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
RRM2 [1] RRM2 💬 |
D00341 D00341 💬 |
Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬 |
918 | Pyrimidine metabolism 💬 4 genes, 8 drugs (DrugBank) and 32 diseases |
RRM2 [1] RRM2 💬 |
D00341 D00341 💬 |
Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬 |
919 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
BRAF [6] BRAF, FLT4, KDR, KIT, PDGFRB, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
920 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
BRAF [6] BRAF, FLT4, KDR, KIT, PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
921 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
DRD2 [1] DRD2 💬 |
D01462 D01462 💬 |
Lisuride | 006 [2] 6 , 86 💬 |
922 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
DRD2 [1] DRD2 💬 |
D08132 D08132 💬 |
Lisuride | 006 [2] 6 , 86 💬 |
923 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
DRD2 [1] DRD2 💬 |
D01348 D01348 💬 |
Terguride | 051 [2] 51, 86 💬 |
924 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
925 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
KIT [2] KIT, PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
926 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
KIT [2] KIT, PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
927 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
KIT [3] KIT, PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
928 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
929 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
ABL1 [3] ABL1, KIT, PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
930 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
ABL1 [3] ABL1, KIT, PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
931 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
ABL1 [4] ABL1, KIT, PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
932 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
933 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
FLT3 [6] FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
934 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
FLT3 [6] FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
935 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
936 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
BRAF [3] BRAF, PDGFRB, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
937 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
BRAF [3] BRAF, PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
938 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D02212 D02212 💬 |
Ipratropium | 006 [2] 6 , 86 💬 |
939 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
940 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
PDGFRA [1] PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
941 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
PDGFRA [1] PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
942 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
943 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
ADRB1 [1] ADRB1 💬 |
D00634 D00634 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
944 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
ADRB1 [1] ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
945 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00255 D00255 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
946 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
D03415 D03415 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
947 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
ADRB2 [1] ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 [14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬 |
948 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
949 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
950 | Relaxin signaling pathway 💬 18 genes, 25 drugs (DrugBank) and 38 diseases |
EDNRB [1] EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
951 | Relaxin signaling pathway 💬 18 genes, 25 drugs (DrugBank) and 38 diseases |
EDNRB [1] EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
952 | Relaxin signaling pathway 💬 18 genes, 25 drugs (DrugBank) and 38 diseases |
EDNRB [1] EDNRB 💬 |
D10135 D10135 💬 |
Macitentan | 051 [5] 51, 85, 86, 88, 210 💬 |
953 | Relaxin signaling pathway 💬 18 genes, 25 drugs (DrugBank) and 38 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
954 | Relaxin signaling pathway 💬 18 genes, 25 drugs (DrugBank) and 38 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
955 | Relaxin signaling pathway 💬 18 genes, 25 drugs (DrugBank) and 38 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
956 | Relaxin signaling pathway 💬 18 genes, 25 drugs (DrugBank) and 38 diseases |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
957 | Renal cell carcinoma 💬 12 genes, 12 drugs (DrugBank) and 21 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
958 | Renal cell carcinoma 💬 12 genes, 12 drugs (DrugBank) and 21 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
959 | Renal cell carcinoma 💬 12 genes, 12 drugs (DrugBank) and 21 diseases |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
960 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ACE [1] ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 [8] 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
961 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ADRB1 [1] ADRB1 💬 |
D00634 D00634 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
962 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ADRB1 [1] ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
963 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00255 D00255 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
964 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
D03415 D03415 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
965 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ADRB2 [1] ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 [14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬 |
966 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
AGTR1 [1] AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
967 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
AGTR1 [1] AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
968 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
969 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
970 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
971 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
972 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
973 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
EDNRA [1] EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬 |
974 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
EDNRA [1] EDNRA 💬 |
D01227 D01227 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
975 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
EDNRA [1] EDNRA 💬 |
D07538 D07538 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
976 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
EDNRA [1] EDNRA 💬 |
D10135 D10135 💬 |
Macitentan | 051 [5] 51, 85, 86, 88, 210 💬 |
977 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
EDNRA [1] EDNRA 💬 |
D07171 D07171 💬 |
Sitaxentan | 086 [1] 86 💬 |
978 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬 |
979 | Renin-angiotensin system 💬 6 genes, 21 drugs (DrugBank) and 32 diseases |
ACE [1] ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 [8] 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
980 | Renin-angiotensin system 💬 6 genes, 21 drugs (DrugBank) and 32 diseases |
AGTR1 [2] AGTR1, AGTR2 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
981 | Renin-angiotensin system 💬 6 genes, 21 drugs (DrugBank) and 32 diseases |
AGTR1 [2] AGTR1, AGTR2 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
982 | Renin-angiotensin system 💬 6 genes, 21 drugs (DrugBank) and 32 diseases |
ANPEP [1] ANPEP 💬 |
D00087 D00087 💬 |
Ubenimex | 086 [1] 86 💬 |
983 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
984 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
985 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
986 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
987 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
988 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
989 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
990 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
991 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D00255 D00255 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
992 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D03415 D03415 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
993 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
ADRB1 [1] ADRB1 💬 |
D00634 D00634 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
994 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
ADRB1 [1] ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
995 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
ADRB2 [1] ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 [14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬 |
996 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
CHRM3 [1] CHRM3 💬 |
D02212 D02212 💬 |
Ipratropium | 006 [2] 6 , 86 💬 |
997 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬 |
998 | Salmonella infection 💬 25 genes, 32 drugs (DrugBank) and 62 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
999 | Salmonella infection 💬 25 genes, 32 drugs (DrugBank) and 62 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1000 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1001 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1002 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
1003 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
1004 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
1005 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
1006 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
1007 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
1008 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
1009 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
SLC6A4 [1] SLC6A4 💬 |
D00326 D00326 💬 |
Fluoxetine | 013 [6] 13, 17, 78, 86, 179, 206 💬 |
1010 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
SLC6A4 [1] SLC6A4 💬 |
D00823 D00823 💬 |
Fluoxetine | 013 [6] 13, 17, 78, 86, 179, 206 💬 |
1011 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
1012 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
1013 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1014 | Signaling pathways regulating pluripotency of stem cells 💬 20 genes, 24 drugs (DrugBank) and 43 diseases |
ACVR2A [1] ACVR2A 💬 |
D09670 D09670 💬 |
Sotatercept | 086 [2] 86, 284 💬 |
1015 | Signaling pathways regulating pluripotency of stem cells 💬 20 genes, 24 drugs (DrugBank) and 43 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1016 | Signaling pathways regulating pluripotency of stem cells 💬 20 genes, 24 drugs (DrugBank) and 43 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1017 | Small cell lung cancer 💬 11 genes, 35 drugs (DrugBank) and 51 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
1018 | Small cell lung cancer 💬 11 genes, 35 drugs (DrugBank) and 51 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
1019 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
1020 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1021 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1022 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
1023 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1024 | Steroid hormone biosynthesis 💬 7 genes, 10 drugs (DrugBank) and 14 diseases |
CYP19A1 [1] CYP19A1 💬 |
D00960 D00960 💬 |
Anastrozole | 078 [3] 78, 86, 193 💬 |
1025 | Synaptic vesicle cycle 💬 7 genes, 29 drugs (DrugBank) and 37 diseases |
SLC6A4 [1] SLC6A4 💬 |
D00326 D00326 💬 |
Fluoxetine | 013 [6] 13, 17, 78, 86, 179, 206 💬 |
1026 | Synaptic vesicle cycle 💬 7 genes, 29 drugs (DrugBank) and 37 diseases |
SLC6A4 [1] SLC6A4 💬 |
D00823 D00823 💬 |
Fluoxetine | 013 [6] 13, 17, 78, 86, 179, 206 💬 |
1027 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1028 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1029 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
CACNA1C [1] CACNA1C 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
1030 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
CACNA1C [1] CACNA1C 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
1031 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
CACNA1C [1] CACNA1C 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
1032 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
CACNA1C [1] CACNA1C 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
1033 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
CACNA1C [1] CACNA1C 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
1034 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
CHRM3 [1] CHRM3 💬 |
D02212 D02212 💬 |
Ipratropium | 006 [2] 6 , 86 💬 |
1035 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D00358 D00358 💬 |
Lidocaine | 006 [12] 6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬 |
1036 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D02086 D02086 💬 |
Lidocaine | 006 [12] 6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬 |
1037 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D08127 D08127 💬 |
Lidocaine | 006 [12] 6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬 |
1038 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
TAS1R2 [2] TAS1R2, TAS1R3 💬 |
D02381 D02381 💬 |
Aspartame | 006 [5] 6 , 13, 67, 86, 230 💬 |
1039 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
HMGCR [1] HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
1040 | TGF-beta signaling pathway 💬 11 genes, 20 drugs (DrugBank) and 54 diseases |
ACVR2A [1] ACVR2A 💬 |
D09670 D09670 💬 |
Sotatercept | 086 [2] 86, 284 💬 |
1041 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
1042 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
1043 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1044 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
1045 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1046 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
1047 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
1048 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
1049 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
1050 | Thyroid cancer 💬 8 genes, 12 drugs (DrugBank) and 25 diseases |
BRAF [2] BRAF, RET 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1051 | Thyroid cancer 💬 8 genes, 12 drugs (DrugBank) and 25 diseases |
BRAF [2] BRAF, RET 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1052 | Thyroid cancer 💬 8 genes, 12 drugs (DrugBank) and 25 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
1053 | Thyroid cancer 💬 8 genes, 12 drugs (DrugBank) and 25 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
1054 | Thyroid hormone signaling pathway 💬 22 genes, 35 drugs (DrugBank) and 61 diseases |
ESR1 [1] ESR1 💬 |
D01161 D01161 💬 |
Fulvestrant | 049 [2] 49, 86 💬 |
1055 | Thyroid hormone signaling pathway 💬 22 genes, 35 drugs (DrugBank) and 61 diseases |
ESR1 [1] ESR1 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
1056 | Thyroid hormone signaling pathway 💬 22 genes, 35 drugs (DrugBank) and 61 diseases |
ESR1 [1] ESR1 💬 |
D00966 D00966 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
1057 | Thyroid hormone signaling pathway 💬 22 genes, 35 drugs (DrugBank) and 61 diseases |
ESR1 [1] ESR1 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
1058 | Thyroid hormone signaling pathway 💬 22 genes, 35 drugs (DrugBank) and 61 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1059 | Thyroid hormone signaling pathway 💬 22 genes, 35 drugs (DrugBank) and 61 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1060 | Thyroid hormone signaling pathway 💬 22 genes, 35 drugs (DrugBank) and 61 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1061 | Tight junction 💬 10 genes, 26 drugs (DrugBank) and 40 diseases |
CACNA1D [1] CACNA1D 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
1062 | Tight junction 💬 10 genes, 26 drugs (DrugBank) and 40 diseases |
CACNA1D [1] CACNA1D 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
1063 | Tight junction 💬 10 genes, 26 drugs (DrugBank) and 40 diseases |
CACNA1D [1] CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
1064 | Tight junction 💬 10 genes, 26 drugs (DrugBank) and 40 diseases |
CACNA1D [1] CACNA1D 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
1065 | Tight junction 💬 10 genes, 26 drugs (DrugBank) and 40 diseases |
CACNA1D [1] CACNA1D 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
1066 | Tight junction 💬 10 genes, 26 drugs (DrugBank) and 40 diseases |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
1067 | Tight junction 💬 10 genes, 26 drugs (DrugBank) and 40 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
1068 | Tight junction 💬 10 genes, 26 drugs (DrugBank) and 40 diseases |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
1069 | TNF signaling pathway 💬 18 genes, 51 drugs (DrugBank) and 79 diseases |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
1070 | TNF signaling pathway 💬 18 genes, 51 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
1071 | TNF signaling pathway 💬 18 genes, 51 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
1072 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
FLT3 [1] FLT3 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1073 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
FLT3 [1] FLT3 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1074 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
IL1R2 [1] IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
1075 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
1076 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
1077 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1078 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1079 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
1080 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
1081 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
1082 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
1083 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
1084 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
CACNA1G [1] CACNA1G 💬 |
D01303 D01303 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
1085 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
CACNA1G [1] CACNA1G 💬 |
D07971 D07971 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
1086 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1087 | Ubiquitin mediated proteolysis 💬 2 genes, 2 drugs (DrugBank) and 9 diseases |
KEAP1 [1] KEAP1 💬 |
D03846 D03846 💬 |
Dimethyl fumarate | 013 [4] 13, 51, 86, 296 💬 |
1088 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00255 D00255 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
1089 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D03415 D03415 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
1090 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
AGTR1 [1] AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
1091 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
AGTR1 [1] AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
1092 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
AVPR1A [1] AVPR1A 💬 |
D01236 D01236 💬 |
Conivaptan | 086 [1] 86 💬 |
1093 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
AVPR1A [1] AVPR1A 💬 |
D07748 D07748 💬 |
Conivaptan | 086 [1] 86 💬 |
1094 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1095 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1096 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
1097 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
1098 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
1099 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
1100 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
1101 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
EDNRA [1] EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬 |
1102 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
EDNRA [1] EDNRA 💬 |
D01227 D01227 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
1103 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
EDNRA [1] EDNRA 💬 |
D07538 D07538 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
1104 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
EDNRA [1] EDNRA 💬 |
D10135 D10135 💬 |
Macitentan | 051 [5] 51, 85, 86, 88, 210 💬 |
1105 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
EDNRA [1] EDNRA 💬 |
D07171 D07171 💬 |
Sitaxentan | 086 [1] 86 💬 |
1106 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬 |
1107 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
PTGIR [1] PTGIR 💬 |
D02720 D02720 💬 |
Beraprost | 086 [1] 86 💬 |
1108 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
PTGIR [1] PTGIR 💬 |
D00106 D00106 💬 |
Epoprostenol | 086 [1] 86 💬 |
1109 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
PTGIR [1] PTGIR 💬 |
D01337 D01337 💬 |
Epoprostenol | 086 [1] 86 💬 |
1110 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
PTGIR [1] PTGIR 💬 |
D02721 D02721 💬 |
Iloprost | 051 [4] 51, 84, 85, 86 💬 |
1111 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
PTGIR [1] PTGIR 💬 |
D10725 D10725 💬 |
Ralinepag | 086 [1] 86 💬 |
1112 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
PTGIR [1] PTGIR 💬 |
D09994 D09994 💬 |
Selexipag | 051 [5] 51, 70, 84, 86, 88 💬 |
1113 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
PTGIR [1] PTGIR 💬 |
D06213 D06213 💬 |
Treprostinil | 051 [6] 51, 84, 85, 86, 88, 210 💬 |
1114 | Vasopressin-regulated water reabsorption 💬 1 gene, 5 drugs (DrugBank) and 9 diseases |
AVPR2 [1] AVPR2 💬 |
D01236 D01236 💬 |
Conivaptan | 086 [1] 86 💬 |
1115 | Vasopressin-regulated water reabsorption 💬 1 gene, 5 drugs (DrugBank) and 9 diseases |
AVPR2 [1] AVPR2 💬 |
D07748 D07748 💬 |
Conivaptan | 086 [1] 86 💬 |
1116 | VEGF signaling pathway 💬 20 genes, 48 drugs (DrugBank) and 84 diseases |
KDR [2] KDR, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1117 | VEGF signaling pathway 💬 20 genes, 48 drugs (DrugBank) and 84 diseases |
KDR [2] KDR, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
1118 | VEGF signaling pathway 💬 20 genes, 48 drugs (DrugBank) and 84 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
1119 | VEGF signaling pathway 💬 20 genes, 48 drugs (DrugBank) and 84 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
1120 | VEGF signaling pathway 💬 20 genes, 48 drugs (DrugBank) and 84 diseases |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
1121 | Viral myocarditis 💬 29 genes, 18 drugs (DrugBank) and 46 diseases |
ABL1 [1] ABL1 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
1122 | Viral myocarditis 💬 29 genes, 18 drugs (DrugBank) and 46 diseases |
ABL1 [1] ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
1123 | Viral myocarditis 💬 29 genes, 18 drugs (DrugBank) and 46 diseases |
ABL1 [1] ABL1 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
1124 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 27 drugs (DrugBank) and 58 diseases |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |