Target Gene/Pathway💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
1 | Acute myeloid leukemia 💬 15 genes, 25 drugs (DrugBank) and 59 diseases |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
2 | Acute myeloid leukemia 💬 15 genes, 25 drugs (DrugBank) and 59 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
3 | Acute myeloid leukemia 💬 15 genes, 25 drugs (DrugBank) and 59 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
4 | Acute myeloid leukemia 💬 15 genes, 25 drugs (DrugBank) and 59 diseases |
RARA [1] RARA 💬 |
D01418 D01418 💬 |
Tamibarotene | 026 [2] 26, 96 💬 |
5 | Adherens junction 💬 9 genes, 18 drugs (DrugBank) and 24 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
6 | Adherens junction 💬 9 genes, 18 drugs (DrugBank) and 24 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
7 | Adherens junction 💬 9 genes, 18 drugs (DrugBank) and 24 diseases |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
8 | Adherens junction 💬 9 genes, 18 drugs (DrugBank) and 24 diseases |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
9 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
JAK2 [1] JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
10 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
11 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
12 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
13 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
14 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
15 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
16 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
17 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D00095 D00095 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
18 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D00996 D00996 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
19 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D02149 D02149 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
20 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
21 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
22 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
23 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
24 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
SCN5A [1] SCN5A 💬 |
D01450 D01450 💬 |
Bupivacaine | 046 [8] 46, 51, 53, 70, 96, 168, 226, 298 💬 |
25 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
SCN5A [1] SCN5A 💬 |
D07552 D07552 💬 |
Bupivacaine | 046 [8] 46, 51, 53, 70, 96, 168, 226, 298 💬 |
26 | African trypanosomiasis 💬 7 genes, 19 drugs (DrugBank) and 57 diseases |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
27 | African trypanosomiasis 💬 7 genes, 19 drugs (DrugBank) and 57 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
28 | African trypanosomiasis 💬 7 genes, 19 drugs (DrugBank) and 57 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
29 | African trypanosomiasis 💬 7 genes, 19 drugs (DrugBank) and 57 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
30 | African trypanosomiasis 💬 7 genes, 19 drugs (DrugBank) and 57 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
31 | African trypanosomiasis 💬 7 genes, 19 drugs (DrugBank) and 57 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
32 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
33 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
34 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
JAK2 [1] JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
35 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
36 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
37 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
38 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
39 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
40 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
ADORA2A [1] ADORA2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
41 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
ADORA2A [1] ADORA2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
42 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
43 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
44 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
45 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
HDAC1 [11] HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
46 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
SLC6A3 [1] SLC6A3 💬 |
D00817 D00817 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
47 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
SLC6A3 [1] SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
48 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
SLC6A3 [1] SLC6A3 💬 |
D07938 D07938 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
49 | Aldosterone synthesis and secretion 💬 18 genes, 34 drugs (DrugBank) and 64 diseases |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
50 | Aldosterone synthesis and secretion 💬 18 genes, 34 drugs (DrugBank) and 64 diseases |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
51 | Aldosterone synthesis and secretion 💬 18 genes, 34 drugs (DrugBank) and 64 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
52 | Aldosterone synthesis and secretion 💬 18 genes, 34 drugs (DrugBank) and 64 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
53 | Aldosterone synthesis and secretion 💬 18 genes, 34 drugs (DrugBank) and 64 diseases |
PDE2A [1] PDE2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
54 | Aldosterone synthesis and secretion 💬 18 genes, 34 drugs (DrugBank) and 64 diseases |
PDE2A [1] PDE2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
55 | Aldosterone-regulated sodium reabsorption 💬 12 genes, 12 drugs (DrugBank) and 23 diseases |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
56 | Aldosterone-regulated sodium reabsorption 💬 12 genes, 12 drugs (DrugBank) and 23 diseases |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
57 | Allograft rejection 💬 30 genes, 22 drugs (DrugBank) and 57 diseases |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
58 | Allograft rejection 💬 30 genes, 22 drugs (DrugBank) and 57 diseases |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
59 | Allograft rejection 💬 30 genes, 22 drugs (DrugBank) and 57 diseases |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
60 | Allograft rejection 💬 30 genes, 22 drugs (DrugBank) and 57 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
61 | Allograft rejection 💬 30 genes, 22 drugs (DrugBank) and 57 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
62 | Allograft rejection 💬 30 genes, 22 drugs (DrugBank) and 57 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
63 | Allograft rejection 💬 30 genes, 22 drugs (DrugBank) and 57 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
64 | Allograft rejection 💬 30 genes, 22 drugs (DrugBank) and 57 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
65 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
66 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
67 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
68 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
69 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
70 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
71 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
72 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
73 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
74 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
75 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
76 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
77 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
78 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
79 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
80 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
81 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
82 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
83 | Amoebiasis 💬 17 genes, 25 drugs (DrugBank) and 62 diseases |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
84 | Amoebiasis 💬 17 genes, 25 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
85 | Amoebiasis 💬 17 genes, 25 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
86 | Amoebiasis 💬 17 genes, 25 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
87 | Amoebiasis 💬 17 genes, 25 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
88 | Amoebiasis 💬 17 genes, 25 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
89 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
90 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
91 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
92 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
93 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
94 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
HDAC1 [2] HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
95 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
96 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
97 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
SLC6A3 [1] SLC6A3 💬 |
D00817 D00817 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
98 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
SLC6A3 [1] SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
99 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
SLC6A3 [1] SLC6A3 💬 |
D07938 D07938 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
100 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
ADRA1A [1] ADRA1A 💬 |
D00095 D00095 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
101 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
ADRA1A [1] ADRA1A 💬 |
D00996 D00996 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
102 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
ADRA1A [1] ADRA1A 💬 |
D02149 D02149 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
103 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
HMGCR [1] HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
104 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
HMGCR [1] HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
105 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
HMGCR [1] HMGCR 💬 |
D00893 D00893 💬 |
Pravastatin | 013 [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
106 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
HMGCR [1] HMGCR 💬 |
D08410 D08410 💬 |
Pravastatin | 013 [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
107 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
HMGCR [1] HMGCR 💬 |
D01915 D01915 💬 |
Rosuvastatin | 006 [11] 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
108 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
HMGCR [1] HMGCR 💬 |
D08492 D08492 💬 |
Rosuvastatin | 006 [11] 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
109 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
110 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
111 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
112 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
113 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
114 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
115 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
116 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
117 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
GRIN1 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
118 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
GRIN1 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
119 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
GRIN1 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
120 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
HDAC6 [1] HDAC6 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
121 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
122 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
123 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
124 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
125 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
126 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
127 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
128 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
129 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
130 | Antifolate resistance 💬 7 genes, 20 drugs (DrugBank) and 64 diseases |
DHFR [2] DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
131 | Antifolate resistance 💬 7 genes, 20 drugs (DrugBank) and 64 diseases |
DHFR [2] DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
132 | Antifolate resistance 💬 7 genes, 20 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
133 | Antifolate resistance 💬 7 genes, 20 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
134 | Antifolate resistance 💬 7 genes, 20 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
135 | Antifolate resistance 💬 7 genes, 20 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
136 | Antifolate resistance 💬 7 genes, 20 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
137 | Antigen processing and presentation 💬 23 genes, 15 drugs (DrugBank) and 53 diseases |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
138 | Antigen processing and presentation 💬 23 genes, 15 drugs (DrugBank) and 53 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
139 | Antigen processing and presentation 💬 23 genes, 15 drugs (DrugBank) and 53 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
140 | Antigen processing and presentation 💬 23 genes, 15 drugs (DrugBank) and 53 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
141 | Antigen processing and presentation 💬 23 genes, 15 drugs (DrugBank) and 53 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
142 | Antigen processing and presentation 💬 23 genes, 15 drugs (DrugBank) and 53 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
143 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
144 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
145 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
HDAC4 [2] HDAC4, HDAC5 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
146 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
147 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
148 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PDE3B [1] PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
149 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PDE3B [1] PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
150 | Apoptosis 💬 14 genes, 23 drugs (DrugBank) and 54 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
151 | Apoptosis 💬 14 genes, 23 drugs (DrugBank) and 54 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
152 | Apoptosis 💬 14 genes, 23 drugs (DrugBank) and 54 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
153 | Apoptosis 💬 14 genes, 23 drugs (DrugBank) and 54 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
154 | Apoptosis 💬 14 genes, 23 drugs (DrugBank) and 54 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
155 | Arachidonic acid metabolism 💬 4 genes, 25 drugs (DrugBank) and 38 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
156 | Arachidonic acid metabolism 💬 4 genes, 25 drugs (DrugBank) and 38 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
157 | Arrhythmogenic right ventricular cardiomyopathy 💬 11 genes, 24 drugs (DrugBank) and 28 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
158 | Arrhythmogenic right ventricular cardiomyopathy 💬 11 genes, 24 drugs (DrugBank) and 28 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
159 | Arrhythmogenic right ventricular cardiomyopathy 💬 11 genes, 24 drugs (DrugBank) and 28 diseases |
ITGA4 [1] ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 [6] 13, 15, 25, 46, 63, 96 💬 |
160 | Arrhythmogenic right ventricular cardiomyopathy 💬 11 genes, 24 drugs (DrugBank) and 28 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
D10540 D10540 💬 |
Abrilumab | 096 [2] 96, 97 💬 |
161 | Arrhythmogenic right ventricular cardiomyopathy 💬 11 genes, 24 drugs (DrugBank) and 28 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 |
162 | Arrhythmogenic right ventricular cardiomyopathy 💬 11 genes, 24 drugs (DrugBank) and 28 diseases |
ITGB7 [1] ITGB7 💬 |
D09901 D09901 💬 |
Etrolizumab | 096 [2] 96, 97 💬 |
163 | Asthma 💬 21 genes, 21 drugs (DrugBank) and 55 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
164 | Asthma 💬 21 genes, 21 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
165 | Asthma 💬 21 genes, 21 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
166 | Asthma 💬 21 genes, 21 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
167 | Asthma 💬 21 genes, 21 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
168 | Asthma 💬 21 genes, 21 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
169 | Autoimmune thyroid disease 💬 41 genes, 14 drugs (DrugBank) and 37 diseases |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
170 | Autoimmune thyroid disease 💬 41 genes, 14 drugs (DrugBank) and 37 diseases |
CTLA4 [1] CTLA4 💬 |
D06657 D06657 💬 |
Tremelimumab | 096 [1] 96 💬 |
171 | Autoimmune thyroid disease 💬 41 genes, 14 drugs (DrugBank) and 37 diseases |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
172 | Autophagy - animal 💬 13 genes, 15 drugs (DrugBank) and 57 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
173 | Autophagy - animal 💬 13 genes, 15 drugs (DrugBank) and 57 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
174 | Autophagy - animal 💬 13 genes, 15 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
175 | Autophagy - animal 💬 13 genes, 15 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
176 | Autophagy - other 💬 1 gene, 3 drugs (DrugBank) and 41 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
177 | Autophagy - other 💬 1 gene, 3 drugs (DrugBank) and 41 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
178 | Axon guidance 💬 21 genes, 19 drugs (DrugBank) and 65 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
179 | Axon guidance 💬 21 genes, 19 drugs (DrugBank) and 65 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
180 | B cell receptor signaling pathway 💬 16 genes, 19 drugs (DrugBank) and 63 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
181 | B cell receptor signaling pathway 💬 16 genes, 19 drugs (DrugBank) and 63 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
182 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
HMGCR [1] HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
183 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
HMGCR [1] HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
184 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
HMGCR [1] HMGCR 💬 |
D00893 D00893 💬 |
Pravastatin | 013 [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
185 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
HMGCR [1] HMGCR 💬 |
D08410 D08410 💬 |
Pravastatin | 013 [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
186 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
HMGCR [1] HMGCR 💬 |
D01915 D01915 💬 |
Rosuvastatin | 006 [11] 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
187 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
HMGCR [1] HMGCR 💬 |
D08492 D08492 💬 |
Rosuvastatin | 006 [11] 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
188 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
NR1H4 [1] NR1H4 💬 |
D00163 D00163 💬 |
Chenodeoxycholic acid | 020 [4] 20, 96, 234, 263 💬 |
189 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
NR1H4 [1] NR1H4 💬 |
D00734 D00734 💬 |
Ursodeoxycholic acid | 006 [13] 6 , 8 , 20, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬 |
190 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 45 diseases |
DHFR [2] DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
191 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 45 diseases |
DHFR [2] DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
192 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 45 diseases |
NQO1 [2] NQO1, VKORC1 💬 |
D00564 D00564 💬 |
Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
193 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 45 diseases |
NQO1 [2] NQO1, VKORC1 💬 |
D01280 D01280 💬 |
Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
194 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 45 diseases |
NQO1 [2] NQO1, VKORC1 💬 |
D08682 D08682 💬 |
Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
195 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
196 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
197 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
198 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
199 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
200 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
201 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
TNFSF11 [1] TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 [7] 46, 50, 93, 95, 96, 274, 299 💬 |
202 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
IL12A [3] IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
203 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
IL23A [1] IL23A 💬 |
D10912 D10912 💬 |
Brazikumab | 096 [2] 96, 97 💬 |
204 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
IL23A [1] IL23A 💬 |
D10438 D10438 💬 |
Guselkumab | 037 [4] 37, 41, 96, 97 💬 |
205 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
IL23A [1] IL23A 💬 |
D11123 D11123 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 |
206 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
IL23A [1] IL23A 💬 |
D11052 D11052 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 |
207 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
208 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
209 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
210 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
211 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
212 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
213 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
214 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
215 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
216 | Caffeine metabolism 💬 1 gene, 2 drugs (DrugBank) and 8 diseases |
XDH [1] XDH 💬 |
D00224 D00224 💬 |
Allopurinol | 006 [6] 6 , 46, 57, 66, 96, 97 💬 |
217 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADORA2A [2] ADORA2A, PDE1B 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
218 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADORA2A [2] ADORA2A, PDE1B 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
219 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
D00095 D00095 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
220 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
D00996 D00996 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
221 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
D02149 D02149 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
222 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
223 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
224 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
225 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
226 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
227 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
228 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
229 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
HRH1 [1] HRH1 💬 |
D00300 D00300 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
230 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
HRH1 [1] HRH1 💬 |
D00669 D00669 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
231 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
HRH1 [1] HRH1 💬 |
D02419 D02419 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
232 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
HRH1 [1] HRH1 💬 |
D03285 D03285 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
233 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
HRH1 [1] HRH1 💬 |
D03360 D03360 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
234 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
HRH1 [1] HRH1 💬 |
D03854 D03854 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
235 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
HRH1 [1] HRH1 💬 |
D00480 D00480 💬 |
Promethazine | 096 [1] 96 💬 |
236 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
HRH1 [1] HRH1 💬 |
D00494 D00494 💬 |
Promethazine | 096 [1] 96 💬 |
237 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
HRH1 [1] HRH1 💬 |
D01242 D01242 💬 |
Promethazine | 096 [1] 96 💬 |
238 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
HRH1 [1] HRH1 💬 |
D03290 D03290 💬 |
Promethazine | 096 [1] 96 💬 |
239 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
HTR4 [1] HTR4 💬 |
D08236 D08236 💬 |
Mosapride | 096 [1] 96 💬 |
240 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
HTR4 [1] HTR4 💬 |
D09205 D09205 💬 |
Prucalopride | 013 [3] 13, 51, 96 💬 |
241 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
242 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
243 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
ADORA1 [8] ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
244 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
ADORA1 [8] ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
245 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00095 D00095 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
246 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00996 D00996 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
247 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
D02149 D02149 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
248 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
249 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
250 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
251 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
252 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
253 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
HTR4 [1] HTR4 💬 |
D08236 D08236 💬 |
Mosapride | 096 [1] 96 💬 |
254 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
HTR4 [1] HTR4 💬 |
D09205 D09205 💬 |
Prucalopride | 013 [3] 13, 51, 96 💬 |
255 | Carbohydrate digestion and absorption 💬 10 genes, 16 drugs (DrugBank) and 28 diseases |
CACNA1D [1] CACNA1D 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
256 | Carbohydrate digestion and absorption 💬 10 genes, 16 drugs (DrugBank) and 28 diseases |
CACNA1D [1] CACNA1D 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
257 | Cardiac muscle contraction 💬 12 genes, 16 drugs (DrugBank) and 25 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
258 | Cardiac muscle contraction 💬 12 genes, 16 drugs (DrugBank) and 25 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
259 | Cell adhesion molecules 💬 32 genes, 19 drugs (DrugBank) and 37 diseases |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
260 | Cell adhesion molecules 💬 32 genes, 19 drugs (DrugBank) and 37 diseases |
CTLA4 [1] CTLA4 💬 |
D06657 D06657 💬 |
Tremelimumab | 096 [1] 96 💬 |
261 | Cell adhesion molecules 💬 32 genes, 19 drugs (DrugBank) and 37 diseases |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
262 | Cell adhesion molecules 💬 32 genes, 19 drugs (DrugBank) and 37 diseases |
ITGA4 [1] ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 [6] 13, 15, 25, 46, 63, 96 💬 |
263 | Cell adhesion molecules 💬 32 genes, 19 drugs (DrugBank) and 37 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
D10540 D10540 💬 |
Abrilumab | 096 [2] 96, 97 💬 |
264 | Cell adhesion molecules 💬 32 genes, 19 drugs (DrugBank) and 37 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 |
265 | Cell adhesion molecules 💬 32 genes, 19 drugs (DrugBank) and 37 diseases |
ITGAL [1] ITGAL 💬 |
D03959 D03959 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 |
266 | Cell adhesion molecules 💬 32 genes, 19 drugs (DrugBank) and 37 diseases |
ITGB7 [1] ITGB7 💬 |
D09901 D09901 💬 |
Etrolizumab | 096 [2] 96, 97 💬 |
267 | Cell adhesion molecules 💬 32 genes, 19 drugs (DrugBank) and 37 diseases |
PDCD1 [1] PDCD1 💬 |
D10316 D10316 💬 |
Nivolumab | 013 [12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬 |
268 | Cell cycle 💬 7 genes, 8 drugs (DrugBank) and 23 diseases |
HDAC1 [2] HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
269 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
CACNA1D [1] CACNA1D 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
270 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
CACNA1D [1] CACNA1D 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
271 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
HLA-A [6] HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
272 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
273 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
274 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
275 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
276 | Central carbon metabolism in cancer 💬 18 genes, 24 drugs (DrugBank) and 55 diseases |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
277 | Central carbon metabolism in cancer 💬 18 genes, 24 drugs (DrugBank) and 55 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
278 | Central carbon metabolism in cancer 💬 18 genes, 24 drugs (DrugBank) and 55 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
279 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADORA1 [5] ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
280 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADORA1 [5] ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
281 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D00095 D00095 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
282 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D00996 D00996 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
283 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D02149 D02149 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
284 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
285 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
286 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
287 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
288 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
289 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
290 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
OPRD1 [1] OPRD1 💬 |
D02095 D02095 💬 |
Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
291 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
OPRD1 [1] OPRD1 💬 |
D05113 D05113 💬 |
Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
292 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
293 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
294 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
ACE [1] ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 [8] 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
295 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D05092 D05092 💬 |
Muromonab | 060 [3] 60, 96, 97 💬 |
296 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D06314 D06314 💬 |
Visilizumab | 096 [2] 96, 97 💬 |
297 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
298 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
299 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
300 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
301 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
302 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
303 | Chemical carcinogenesis 💬 5 genes, 26 drugs (DrugBank) and 37 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
304 | Chemical carcinogenesis 💬 5 genes, 26 drugs (DrugBank) and 37 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
305 | Chemokine signaling pathway 💬 20 genes, 23 drugs (DrugBank) and 41 diseases |
JAK2 [2] JAK2, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
306 | Choline metabolism in cancer 💬 10 genes, 20 drugs (DrugBank) and 51 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
307 | Choline metabolism in cancer 💬 10 genes, 20 drugs (DrugBank) and 51 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
308 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
309 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
310 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
JAK2 [1] JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
311 | Chronic myeloid leukemia 💬 14 genes, 15 drugs (DrugBank) and 28 diseases |
HDAC1 [2] HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
312 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
313 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
314 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
315 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
316 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
317 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
318 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
319 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
320 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
SLC6A3 [1] SLC6A3 💬 |
D00817 D00817 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
321 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
SLC6A3 [1] SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
322 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
SLC6A3 [1] SLC6A3 💬 |
D07938 D07938 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
323 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
324 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D01207 D01207 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
325 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D05259 D05259 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
326 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D05261 D05261 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
327 | Colorectal cancer 💬 14 genes, 19 drugs (DrugBank) and 49 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
328 | Colorectal cancer 💬 14 genes, 19 drugs (DrugBank) and 49 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
329 | Complement and coagulation cascades 💬 15 genes, 24 drugs (DrugBank) and 42 diseases |
F10 [1] F10 💬 |
D03213 D03213 💬 |
Apixaban | 096 [3] 96, 97, 222 💬 |
330 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
ACE [1] ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 [8] 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
331 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
332 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
333 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 |
334 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 |
335 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
336 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
337 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
338 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
JAK1 [2] JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
339 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
340 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
341 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
342 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
343 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
344 | Cortisol synthesis and secretion 💬 14 genes, 30 drugs (DrugBank) and 62 diseases |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
345 | Cortisol synthesis and secretion 💬 14 genes, 30 drugs (DrugBank) and 62 diseases |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
346 | Cortisol synthesis and secretion 💬 14 genes, 30 drugs (DrugBank) and 62 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
347 | Cortisol synthesis and secretion 💬 14 genes, 30 drugs (DrugBank) and 62 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
348 | Cushing syndrome 💬 21 genes, 43 drugs (DrugBank) and 66 diseases |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
349 | Cushing syndrome 💬 21 genes, 43 drugs (DrugBank) and 66 diseases |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
350 | Cushing syndrome 💬 21 genes, 43 drugs (DrugBank) and 66 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
351 | Cushing syndrome 💬 21 genes, 43 drugs (DrugBank) and 66 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
352 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
CSF2RA [1] CSF2RA 💬 |
D05803 D05803 💬 |
Sargramostim | 006 [7] 6 , 28, 60, 62, 96, 229, 285 💬 |
353 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
CSF3R [1] CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 [33] 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
354 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
EPOR [1] EPOR 💬 |
D03231 D03231 💬 |
Erythropoietin | 002 [10] 2 , 6 , 13, 18, 22, 46, 47, 70, 95, 96 💬 |
355 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
GHR [1] GHR 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
356 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
GHR [1] GHR 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
357 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [20] 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
358 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 |
359 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 |
360 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IL11RA [1] IL11RA 💬 |
D05266 D05266 💬 |
Oprelvekin | 096 [2] 96, 288 💬 |
361 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IL12A [3] IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
362 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IL23A [1] IL23A 💬 |
D10912 D10912 💬 |
Brazikumab | 096 [2] 96, 97 💬 |
363 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IL23A [1] IL23A 💬 |
D10438 D10438 💬 |
Guselkumab | 037 [4] 37, 41, 96, 97 💬 |
364 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IL23A [1] IL23A 💬 |
D11123 D11123 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 |
365 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IL23A [1] IL23A 💬 |
D11052 D11052 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 |
366 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
367 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
368 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
369 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
370 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
371 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
372 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
TNFSF11 [1] TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 [7] 46, 50, 93, 95, 96, 274, 299 💬 |
373 | Diabetic cardiomyopathy 💬 21 genes, 38 drugs (DrugBank) and 72 diseases |
ACE [1] ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 [8] 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
374 | Diabetic cardiomyopathy 💬 21 genes, 38 drugs (DrugBank) and 72 diseases |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
375 | Diabetic cardiomyopathy 💬 21 genes, 38 drugs (DrugBank) and 72 diseases |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
376 | Diabetic cardiomyopathy 💬 21 genes, 38 drugs (DrugBank) and 72 diseases |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
377 | Diabetic cardiomyopathy 💬 21 genes, 38 drugs (DrugBank) and 72 diseases |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
378 | Diabetic cardiomyopathy 💬 21 genes, 38 drugs (DrugBank) and 72 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
379 | Diabetic cardiomyopathy 💬 21 genes, 38 drugs (DrugBank) and 72 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
380 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
ADRB1 [1] ADRB1 💬 |
D00095 D00095 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
381 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
ADRB1 [1] ADRB1 💬 |
D00996 D00996 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
382 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
ADRB1 [1] ADRB1 💬 |
D02149 D02149 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
383 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
384 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
385 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
ITGA4 [1] ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 [6] 13, 15, 25, 46, 63, 96 💬 |
386 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
D10540 D10540 💬 |
Abrilumab | 096 [2] 96, 97 💬 |
387 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 |
388 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
ITGB7 [1] ITGB7 💬 |
D09901 D09901 💬 |
Etrolizumab | 096 [2] 96, 97 💬 |
389 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
390 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
391 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
392 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
393 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
394 | DNA replication 💬 2 genes, 1 drug (DrugBank) and 9 diseases |
POLA1 [2] POLA1, POLA2 💬 |
D03546 D03546 💬 |
Clofarabine | 019 [9] 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 |
395 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
396 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
397 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
398 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
399 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
400 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
PPP3CA [3] PPP3CA, PPP3CB, PPP3CC 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
401 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
PPP3CA [3] PPP3CA, PPP3CB, PPP3CC 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
402 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
SCN1A [1] SCN1A 💬 |
D01450 D01450 💬 |
Bupivacaine | 046 [8] 46, 51, 53, 70, 96, 168, 226, 298 💬 |
403 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
SCN1A [1] SCN1A 💬 |
D07552 D07552 💬 |
Bupivacaine | 046 [8] 46, 51, 53, 70, 96, 168, 226, 298 💬 |
404 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
SLC6A3 [1] SLC6A3 💬 |
D00817 D00817 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
405 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
SLC6A3 [1] SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
406 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
SLC6A3 [1] SLC6A3 💬 |
D07938 D07938 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
407 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 46 diseases |
HPRT1 [1] HPRT1 💬 |
D00161 D00161 💬 |
Mercaptopurine | 096 [3] 96, 97, 164 💬 |
408 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 46 diseases |
HPRT1 [1] HPRT1 💬 |
D04931 D04931 💬 |
Mercaptopurine | 096 [3] 96, 97, 164 💬 |
409 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 46 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D00752 D00752 💬 |
Mycophenolate mofetil | 002 [32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
410 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 46 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05094 D05094 💬 |
Mycophenolate mofetil | 002 [32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
411 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 46 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05095 D05095 💬 |
Mycophenolate mofetil | 002 [32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
412 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 46 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05096 D05096 💬 |
Mycophenolic acid | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 |
413 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 46 diseases |
RRM1 [1] RRM1 💬 |
D03546 D03546 💬 |
Clofarabine | 019 [9] 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 |
414 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 46 diseases |
RRM1 [1] RRM1 💬 |
D01907 D01907 💬 |
Fludarabine | 013 [18] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬 |
415 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 46 diseases |
RRM1 [1] RRM1 💬 |
D07966 D07966 💬 |
Fludarabine | 013 [18] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬 |
416 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 46 diseases |
XDH [1] XDH 💬 |
D00224 D00224 💬 |
Allopurinol | 006 [6] 6 , 46, 57, 66, 96, 97 💬 |
417 | ECM-receptor interaction 💬 6 genes, 9 drugs (DrugBank) and 14 diseases |
ITGA4 [1] ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 [6] 13, 15, 25, 46, 63, 96 💬 |
418 | ECM-receptor interaction 💬 6 genes, 9 drugs (DrugBank) and 14 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
D10540 D10540 💬 |
Abrilumab | 096 [2] 96, 97 💬 |
419 | ECM-receptor interaction 💬 6 genes, 9 drugs (DrugBank) and 14 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 |
420 | ECM-receptor interaction 💬 6 genes, 9 drugs (DrugBank) and 14 diseases |
ITGB7 [1] ITGB7 💬 |
D09901 D09901 💬 |
Etrolizumab | 096 [2] 96, 97 💬 |
421 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
422 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
423 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
424 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
425 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
JAK1 [2] JAK1, JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
426 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
427 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
428 | Endocrine and other factor-regulated calcium reabsorption 💬 7 genes, 25 drugs (DrugBank) and 49 diseases |
ESR1 [1] ESR1 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
429 | Endocrine and other factor-regulated calcium reabsorption 💬 7 genes, 25 drugs (DrugBank) and 49 diseases |
VDR [1] VDR 💬 |
D01518 D01518 💬 |
Alfacalcidol | 041 [6] 41, 46, 49, 50, 96, 235 💬 |
430 | Endocrine and other factor-regulated calcium reabsorption 💬 7 genes, 25 drugs (DrugBank) and 49 diseases |
VDR [1] VDR 💬 |
D00129 D00129 💬 |
Calcitriol | 037 [8] 37, 46, 49, 66, 96, 158, 235, 326 💬 |
431 | Endocrine and other factor-regulated calcium reabsorption 💬 7 genes, 25 drugs (DrugBank) and 49 diseases |
VDR [1] VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 [23] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 162, 202, 228, 271, 298, 299 💬 |
432 | Endocrine and other factor-regulated calcium reabsorption 💬 7 genes, 25 drugs (DrugBank) and 49 diseases |
VDR [1] VDR 💬 |
D00187 D00187 💬 |
Ergocalciferol | 046 [5] 46, 84, 96, 97, 299 💬 |
433 | Endocrine resistance 💬 19 genes, 37 drugs (DrugBank) and 59 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
434 | Endocrine resistance 💬 19 genes, 37 drugs (DrugBank) and 59 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
435 | Endocrine resistance 💬 19 genes, 37 drugs (DrugBank) and 59 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
436 | Endocrine resistance 💬 19 genes, 37 drugs (DrugBank) and 59 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
437 | Endocrine resistance 💬 19 genes, 37 drugs (DrugBank) and 59 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
438 | Endocytosis 💬 20 genes, 27 drugs (DrugBank) and 50 diseases |
HLA-A [6] HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
439 | Endocytosis 💬 20 genes, 27 drugs (DrugBank) and 50 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
440 | Endocytosis 💬 20 genes, 27 drugs (DrugBank) and 50 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
441 | Endocytosis 💬 20 genes, 27 drugs (DrugBank) and 50 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
442 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D05092 D05092 💬 |
Muromonab | 060 [3] 60, 96, 97 💬 |
443 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D06314 D06314 💬 |
Visilizumab | 096 [2] 96, 97 💬 |
444 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
HDAC1 [2] HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
445 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
446 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 |
447 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 |
448 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
ITGAL [1] ITGAL 💬 |
D03959 D03959 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 |
449 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
450 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
451 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
JAK1 [3] JAK1, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
452 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
453 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
454 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
455 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
456 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
457 | ErbB signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 51 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
458 | ErbB signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 51 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
459 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
460 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
OPRM1 [1] OPRM1 💬 |
D02095 D02095 💬 |
Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
461 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
OPRM1 [1] OPRM1 💬 |
D05113 D05113 💬 |
Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
462 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
RARA [1] RARA 💬 |
D01418 D01418 💬 |
Tamibarotene | 026 [2] 26, 96 💬 |
463 | Fc epsilon RI signaling pathway 💬 19 genes, 35 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
464 | Fc epsilon RI signaling pathway 💬 19 genes, 35 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
465 | Fc epsilon RI signaling pathway 💬 19 genes, 35 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
466 | Fc epsilon RI signaling pathway 💬 19 genes, 35 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
467 | Fc epsilon RI signaling pathway 💬 19 genes, 35 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
468 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
NQO1 [1] NQO1 💬 |
D00564 D00564 💬 |
Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
469 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
NQO1 [1] NQO1 💬 |
D01280 D01280 💬 |
Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
470 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
NQO1 [1] NQO1 💬 |
D08682 D08682 💬 |
Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
471 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
472 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
473 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
474 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
475 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
476 | Focal adhesion 💬 26 genes, 37 drugs (DrugBank) and 42 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
477 | Focal adhesion 💬 26 genes, 37 drugs (DrugBank) and 42 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
478 | Focal adhesion 💬 26 genes, 37 drugs (DrugBank) and 42 diseases |
ITGA4 [1] ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 [6] 13, 15, 25, 46, 63, 96 💬 |
479 | Focal adhesion 💬 26 genes, 37 drugs (DrugBank) and 42 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
D10540 D10540 💬 |
Abrilumab | 096 [2] 96, 97 💬 |
480 | Focal adhesion 💬 26 genes, 37 drugs (DrugBank) and 42 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 |
481 | Focal adhesion 💬 26 genes, 37 drugs (DrugBank) and 42 diseases |
ITGB7 [1] ITGB7 💬 |
D09901 D09901 💬 |
Etrolizumab | 096 [2] 96, 97 💬 |
482 | Folate biosynthesis 💬 6 genes, 4 drugs (DrugBank) and 36 diseases |
DHFR [2] DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
483 | Folate biosynthesis 💬 6 genes, 4 drugs (DrugBank) and 36 diseases |
DHFR [2] DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
484 | FoxO signaling pathway 💬 24 genes, 34 drugs (DrugBank) and 53 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
485 | FoxO signaling pathway 💬 24 genes, 34 drugs (DrugBank) and 53 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
486 | FoxO signaling pathway 💬 24 genes, 34 drugs (DrugBank) and 53 diseases |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
487 | FoxO signaling pathway 💬 24 genes, 34 drugs (DrugBank) and 53 diseases |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
488 | FoxO signaling pathway 💬 24 genes, 34 drugs (DrugBank) and 53 diseases |
S1PR1 [2] S1PR1, S1PR4 💬 |
D10930 D10930 💬 |
Etrasimod | 096 [2] 96, 97 💬 |
489 | FoxO signaling pathway 💬 24 genes, 34 drugs (DrugBank) and 53 diseases |
S1PR1 [2] S1PR1, S1PR4 💬 |
D10968 D10968 💬 |
Ozanimod | 013 [3] 13, 96, 97 💬 |
490 | GABAergic synapse 💬 28 genes, 37 drugs (DrugBank) and 54 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
491 | GABAergic synapse 💬 28 genes, 37 drugs (DrugBank) and 54 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
492 | GABAergic synapse 💬 28 genes, 37 drugs (DrugBank) and 54 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
493 | GABAergic synapse 💬 28 genes, 37 drugs (DrugBank) and 54 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00696 D00696 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
494 | GABAergic synapse 💬 28 genes, 37 drugs (DrugBank) and 54 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D05028 D05028 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
495 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
ADRB1 [1] ADRB1 💬 |
D00095 D00095 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
496 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
ADRB1 [1] ADRB1 💬 |
D00996 D00996 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
497 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
ADRB1 [1] ADRB1 💬 |
D02149 D02149 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
498 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
499 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D01207 D01207 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
500 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D05259 D05259 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
501 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D05261 D05261 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
502 | Gastric cancer 💬 20 genes, 29 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
503 | Gastric cancer 💬 20 genes, 29 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
504 | Glioma 💬 12 genes, 24 drugs (DrugBank) and 56 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
505 | Glioma 💬 12 genes, 24 drugs (DrugBank) and 56 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
506 | Glioma 💬 12 genes, 24 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
507 | Glioma 💬 12 genes, 24 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
508 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PDE3B [1] PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
509 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PDE3B [1] PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
510 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
511 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
512 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
513 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
514 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
515 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
516 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
517 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
518 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
519 | Glutathione metabolism 💬 4 genes, 6 drugs (DrugBank) and 24 diseases |
RRM1 [1] RRM1 💬 |
D03546 D03546 💬 |
Clofarabine | 019 [9] 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 |
520 | Glutathione metabolism 💬 4 genes, 6 drugs (DrugBank) and 24 diseases |
RRM1 [1] RRM1 💬 |
D01907 D01907 💬 |
Fludarabine | 013 [18] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬 |
521 | Glutathione metabolism 💬 4 genes, 6 drugs (DrugBank) and 24 diseases |
RRM1 [1] RRM1 💬 |
D07966 D07966 💬 |
Fludarabine | 013 [18] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬 |
522 | GnRH secretion 💬 19 genes, 36 drugs (DrugBank) and 53 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
523 | GnRH secretion 💬 19 genes, 36 drugs (DrugBank) and 53 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
524 | GnRH secretion 💬 19 genes, 36 drugs (DrugBank) and 53 diseases |
ESR2 [1] ESR2 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
525 | GnRH signaling pathway 💬 15 genes, 33 drugs (DrugBank) and 38 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
526 | GnRH signaling pathway 💬 15 genes, 33 drugs (DrugBank) and 38 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
527 | Graft-versus-host disease 💬 27 genes, 22 drugs (DrugBank) and 61 diseases |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
528 | Graft-versus-host disease 💬 27 genes, 22 drugs (DrugBank) and 61 diseases |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
529 | Graft-versus-host disease 💬 27 genes, 22 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
530 | Graft-versus-host disease 💬 27 genes, 22 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
531 | Graft-versus-host disease 💬 27 genes, 22 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
532 | Graft-versus-host disease 💬 27 genes, 22 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
533 | Graft-versus-host disease 💬 27 genes, 22 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
534 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
535 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
536 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
GHR [1] GHR 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
537 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
GHR [1] GHR 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
538 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [20] 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
539 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
JAK2 [1] JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
540 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
541 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
542 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D05092 D05092 💬 |
Muromonab | 060 [3] 60, 96, 97 💬 |
543 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D06314 D06314 💬 |
Visilizumab | 096 [2] 96, 97 💬 |
544 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
CSF2RA [1] CSF2RA 💬 |
D05803 D05803 💬 |
Sargramostim | 006 [7] 6 , 28, 60, 62, 96, 229, 285 💬 |
545 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
CSF3R [1] CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 [33] 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
546 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
EPOR [1] EPOR 💬 |
D03231 D03231 💬 |
Erythropoietin | 002 [10] 2 , 6 , 13, 18, 22, 46, 47, 70, 95, 96 💬 |
547 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
548 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
IL11RA [1] IL11RA 💬 |
D05266 D05266 💬 |
Oprelvekin | 096 [2] 96, 288 💬 |
549 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
IL2RA [1] IL2RA 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
550 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
ITGA4 [1] ITGA4 💬 |
D10540 D10540 💬 |
Abrilumab | 096 [2] 96, 97 💬 |
551 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
ITGA4 [1] ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 [6] 13, 15, 25, 46, 63, 96 💬 |
552 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
ITGA4 [1] ITGA4 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 |
553 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
554 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
MS4A1 [1] MS4A1 💬 |
D02994 D02994 💬 |
Rituximab | 011 [47] 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬 |
555 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
556 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
557 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
558 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
559 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
560 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
IFNAR1 [1] IFNAR1 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 |
561 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
IFNAR1 [1] IFNAR1 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 |
562 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
563 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
564 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
JAK1 [4] JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
565 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
566 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
567 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
568 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
569 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
570 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 |
571 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 |
572 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
573 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
574 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
JAK1 [2] JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
575 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
576 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
577 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
578 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
579 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
580 | Hepatocellular carcinoma 💬 18 genes, 25 drugs (DrugBank) and 57 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
581 | Hepatocellular carcinoma 💬 18 genes, 25 drugs (DrugBank) and 57 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
582 | Hepatocellular carcinoma 💬 18 genes, 25 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
583 | Hepatocellular carcinoma 💬 18 genes, 25 drugs (DrugBank) and 57 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
584 | Hepatocellular carcinoma 💬 18 genes, 25 drugs (DrugBank) and 57 diseases |
NQO1 [1] NQO1 💬 |
D00564 D00564 💬 |
Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
585 | Hepatocellular carcinoma 💬 18 genes, 25 drugs (DrugBank) and 57 diseases |
NQO1 [1] NQO1 💬 |
D01280 D01280 💬 |
Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
586 | Hepatocellular carcinoma 💬 18 genes, 25 drugs (DrugBank) and 57 diseases |
NQO1 [1] NQO1 💬 |
D08682 D08682 💬 |
Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
587 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
588 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 |
589 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 |
590 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
591 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
592 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
593 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
JAK1 [3] JAK1, JAK2, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
594 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
595 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
596 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
597 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
598 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
599 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
600 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
601 | HIF-1 signaling pathway 💬 20 genes, 40 drugs (DrugBank) and 73 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
602 | HIF-1 signaling pathway 💬 20 genes, 40 drugs (DrugBank) and 73 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
603 | HIF-1 signaling pathway 💬 20 genes, 40 drugs (DrugBank) and 73 diseases |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
604 | HIF-1 signaling pathway 💬 20 genes, 40 drugs (DrugBank) and 73 diseases |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
605 | HIF-1 signaling pathway 💬 20 genes, 40 drugs (DrugBank) and 73 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
606 | HIF-1 signaling pathway 💬 20 genes, 40 drugs (DrugBank) and 73 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
607 | Hippo signaling pathway 💬 6 genes, 4 drugs (DrugBank) and 8 diseases |
SMAD7 [1] SMAD7 💬 |
D10956 D10956 💬 |
Mongersen | 096 [2] 96, 97 💬 |
608 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
HLA-A [6] HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
609 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
610 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
JAK1 [1] JAK1 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
611 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
612 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
613 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
614 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
615 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
616 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
617 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
618 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
619 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
620 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
621 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
622 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
623 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D05092 D05092 💬 |
Muromonab | 060 [3] 60, 96, 97 💬 |
624 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D06314 D06314 💬 |
Visilizumab | 096 [2] 96, 97 💬 |
625 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
HLA-A [6] HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
626 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
627 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
628 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
629 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
630 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
631 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
632 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
633 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
634 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
635 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
HDAC1 [2] HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
636 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
HLA-A [6] HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
637 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 |
638 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 |
639 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
ITGA4 [1] ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 [6] 13, 15, 25, 46, 63, 96 💬 |
640 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
D10540 D10540 💬 |
Abrilumab | 096 [2] 96, 97 💬 |
641 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 |
642 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
ITGB7 [1] ITGB7 💬 |
D09901 D09901 💬 |
Etrolizumab | 096 [2] 96, 97 💬 |
643 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
644 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
645 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
JAK1 [2] JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
646 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
647 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
648 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
649 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
650 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
651 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
652 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
653 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
654 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
655 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D05092 D05092 💬 |
Muromonab | 060 [3] 60, 96, 97 💬 |
656 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D06314 D06314 💬 |
Visilizumab | 096 [2] 96, 97 💬 |
657 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
FDPS [1] FDPS 💬 |
D00942 D00942 💬 |
Risedronic acid | 046 [8] 46, 50, 66, 93, 95, 96, 113, 274 💬 |
658 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
FDPS [1] FDPS 💬 |
D03234 D03234 💬 |
Risedronic acid | 046 [8] 46, 50, 66, 93, 95, 96, 113, 274 💬 |
659 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
FDPS [1] FDPS 💬 |
D08484 D08484 💬 |
Risedronic acid | 046 [8] 46, 50, 66, 93, 95, 96, 113, 274 💬 |
660 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
FDPS [1] FDPS 💬 |
D01968 D01968 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
661 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
FDPS [1] FDPS 💬 |
D06378 D06378 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
662 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
FDPS [1] FDPS 💬 |
D06379 D06379 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
663 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
FDPS [1] FDPS 💬 |
D08689 D08689 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
664 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
665 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
666 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
ITGAL [1] ITGAL 💬 |
D03959 D03959 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 |
667 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
668 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
669 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
JAK1 [2] JAK1, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
670 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
671 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
672 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
673 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
674 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
675 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
676 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
677 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
GRIN1 [2] GRIN1, GRIN2B 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
678 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
GRIN1 [2] GRIN1, GRIN2B 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
679 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
GRIN1 [2] GRIN1, GRIN2B 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
680 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
HDAC1 [2] HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
681 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
682 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
683 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
684 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
685 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
ACE [1] ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 [8] 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
686 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
687 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
688 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
ITGA4 [1] ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 [6] 13, 15, 25, 46, 63, 96 💬 |
689 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
D10540 D10540 💬 |
Abrilumab | 096 [2] 96, 97 💬 |
690 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 |
691 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
ITGB7 [1] ITGB7 💬 |
D09901 D09901 💬 |
Etrolizumab | 096 [2] 96, 97 💬 |
692 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
693 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
694 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
695 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
696 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
697 | IL-17 signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
698 | IL-17 signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
699 | IL-17 signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 79 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
700 | IL-17 signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 79 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
701 | IL-17 signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 79 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
702 | IL-17 signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 79 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
703 | IL-17 signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 79 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
704 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
705 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
IL12A [3] IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
706 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
IL23A [1] IL23A 💬 |
D10912 D10912 💬 |
Brazikumab | 096 [2] 96, 97 💬 |
707 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
IL23A [1] IL23A 💬 |
D10438 D10438 💬 |
Guselkumab | 037 [4] 37, 41, 96, 97 💬 |
708 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
IL23A [1] IL23A 💬 |
D11123 D11123 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 |
709 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
IL23A [1] IL23A 💬 |
D11052 D11052 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 |
710 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
IL2RG [1] IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
711 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
712 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
713 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
714 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
715 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
716 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
HRH1 [1] HRH1 💬 |
D00300 D00300 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
717 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
HRH1 [1] HRH1 💬 |
D00669 D00669 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
718 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
HRH1 [1] HRH1 💬 |
D02419 D02419 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
719 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
HRH1 [1] HRH1 💬 |
D03285 D03285 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
720 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
HRH1 [1] HRH1 💬 |
D03360 D03360 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
721 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
HRH1 [1] HRH1 💬 |
D03854 D03854 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
722 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
HRH1 [1] HRH1 💬 |
D00480 D00480 💬 |
Promethazine | 096 [1] 96 💬 |
723 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
HRH1 [1] HRH1 💬 |
D00494 D00494 💬 |
Promethazine | 096 [1] 96 💬 |
724 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
HRH1 [1] HRH1 💬 |
D01242 D01242 💬 |
Promethazine | 096 [1] 96 💬 |
725 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
HRH1 [1] HRH1 💬 |
D03290 D03290 💬 |
Promethazine | 096 [1] 96 💬 |
726 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
FDPS [1] FDPS 💬 |
D00942 D00942 💬 |
Risedronic acid | 046 [8] 46, 50, 66, 93, 95, 96, 113, 274 💬 |
727 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
FDPS [1] FDPS 💬 |
D03234 D03234 💬 |
Risedronic acid | 046 [8] 46, 50, 66, 93, 95, 96, 113, 274 💬 |
728 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
FDPS [1] FDPS 💬 |
D08484 D08484 💬 |
Risedronic acid | 046 [8] 46, 50, 66, 93, 95, 96, 113, 274 💬 |
729 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
FDPS [1] FDPS 💬 |
D01968 D01968 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
730 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
FDPS [1] FDPS 💬 |
D06378 D06378 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
731 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
FDPS [1] FDPS 💬 |
D06379 D06379 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
732 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
FDPS [1] FDPS 💬 |
D08689 D08689 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
733 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
734 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 |
735 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 |
736 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
737 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
738 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
739 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
JAK1 [3] JAK1, JAK2, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
740 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
741 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
742 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
743 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
744 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
745 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
746 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
747 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
748 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
749 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
750 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
751 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
752 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
753 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
754 | Insulin secretion 💬 13 genes, 40 drugs (DrugBank) and 43 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
755 | Insulin secretion 💬 13 genes, 40 drugs (DrugBank) and 43 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
756 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
757 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
758 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
759 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
760 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
PDE3B [1] PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
761 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
PDE3B [1] PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
762 | Intestinal immune network for IgA production 💬 27 genes, 23 drugs (DrugBank) and 47 diseases |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
763 | Intestinal immune network for IgA production 💬 27 genes, 23 drugs (DrugBank) and 47 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
764 | Intestinal immune network for IgA production 💬 27 genes, 23 drugs (DrugBank) and 47 diseases |
ITGA4 [1] ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 [6] 13, 15, 25, 46, 63, 96 💬 |
765 | Intestinal immune network for IgA production 💬 27 genes, 23 drugs (DrugBank) and 47 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
D10540 D10540 💬 |
Abrilumab | 096 [2] 96, 97 💬 |
766 | Intestinal immune network for IgA production 💬 27 genes, 23 drugs (DrugBank) and 47 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 |
767 | Intestinal immune network for IgA production 💬 27 genes, 23 drugs (DrugBank) and 47 diseases |
ITGB7 [1] ITGB7 💬 |
D09901 D09901 💬 |
Etrolizumab | 096 [2] 96, 97 💬 |
768 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
CSF2RA [1] CSF2RA 💬 |
D05803 D05803 💬 |
Sargramostim | 006 [7] 6 , 28, 60, 62, 96, 229, 285 💬 |
769 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
CSF3R [1] CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 [33] 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
770 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
EPOR [1] EPOR 💬 |
D03231 D03231 💬 |
Erythropoietin | 002 [10] 2 , 6 , 13, 18, 22, 46, 47, 70, 95, 96 💬 |
771 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
GHR [1] GHR 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
772 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
GHR [1] GHR 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
773 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [20] 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
774 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 |
775 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 |
776 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
IL11RA [1] IL11RA 💬 |
D05266 D05266 💬 |
Oprelvekin | 096 [2] 96, 288 💬 |
777 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
IL12A [3] IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
778 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
IL23A [1] IL23A 💬 |
D10912 D10912 💬 |
Brazikumab | 096 [2] 96, 97 💬 |
779 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
IL23A [1] IL23A 💬 |
D10438 D10438 💬 |
Guselkumab | 037 [4] 37, 41, 96, 97 💬 |
780 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
IL23A [1] IL23A 💬 |
D11123 D11123 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 |
781 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
IL23A [1] IL23A 💬 |
D11052 D11052 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 |
782 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
783 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
784 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
785 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
JAK1 [4] JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
786 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
787 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
788 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
CD86 [1] CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
789 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
HLA-A [6] HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
790 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 |
791 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 |
792 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
793 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
794 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
JAK1 [3] JAK1, JAK2, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
795 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
796 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
797 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
798 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
799 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
800 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
801 | Legionellosis 💬 7 genes, 19 drugs (DrugBank) and 58 diseases |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
802 | Legionellosis 💬 7 genes, 19 drugs (DrugBank) and 58 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
803 | Legionellosis 💬 7 genes, 19 drugs (DrugBank) and 58 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
804 | Legionellosis 💬 7 genes, 19 drugs (DrugBank) and 58 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
805 | Legionellosis 💬 7 genes, 19 drugs (DrugBank) and 58 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
806 | Legionellosis 💬 7 genes, 19 drugs (DrugBank) and 58 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
807 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
808 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
809 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
ITGA4 [1] ITGA4 💬 |
D10540 D10540 💬 |
Abrilumab | 096 [2] 96, 97 💬 |
810 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
ITGA4 [1] ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 [6] 13, 15, 25, 46, 63, 96 💬 |
811 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
ITGA4 [1] ITGA4 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 |
812 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
813 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
814 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
JAK1 [2] JAK1, JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
815 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
816 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
817 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
818 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
819 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
820 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
821 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
822 | Leukocyte transendothelial migration 💬 12 genes, 11 drugs (DrugBank) and 25 diseases |
ITGA4 [1] ITGA4 💬 |
D10540 D10540 💬 |
Abrilumab | 096 [2] 96, 97 💬 |
823 | Leukocyte transendothelial migration 💬 12 genes, 11 drugs (DrugBank) and 25 diseases |
ITGA4 [1] ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 [6] 13, 15, 25, 46, 63, 96 💬 |
824 | Leukocyte transendothelial migration 💬 12 genes, 11 drugs (DrugBank) and 25 diseases |
ITGA4 [1] ITGA4 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 |
825 | Leukocyte transendothelial migration 💬 12 genes, 11 drugs (DrugBank) and 25 diseases |
ITGAL [1] ITGAL 💬 |
D03959 D03959 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 |
826 | Long-term depression 💬 12 genes, 15 drugs (DrugBank) and 29 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
827 | Long-term depression 💬 12 genes, 15 drugs (DrugBank) and 29 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
828 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
CACNA1C [1] CACNA1C 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
829 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
CACNA1C [1] CACNA1C 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
830 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
831 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
832 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
833 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
834 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
835 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
836 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
837 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
838 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
839 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
840 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
841 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
842 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
843 | Longevity regulating pathway - multiple species 💬 10 genes, 13 drugs (DrugBank) and 56 diseases |
HDAC1 [2] HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
844 | Longevity regulating pathway - multiple species 💬 10 genes, 13 drugs (DrugBank) and 56 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
845 | Longevity regulating pathway - multiple species 💬 10 genes, 13 drugs (DrugBank) and 56 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
846 | Longevity regulating pathway - multiple species 💬 10 genes, 13 drugs (DrugBank) and 56 diseases |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
847 | Longevity regulating pathway - multiple species 💬 10 genes, 13 drugs (DrugBank) and 56 diseases |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
848 | Longevity regulating pathway - multiple species 💬 10 genes, 13 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
849 | Longevity regulating pathway - multiple species 💬 10 genes, 13 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
850 | Malaria 💬 14 genes, 25 drugs (DrugBank) and 62 diseases |
IL12A [1] IL12A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
851 | Malaria 💬 14 genes, 25 drugs (DrugBank) and 62 diseases |
ITGAL [1] ITGAL 💬 |
D03959 D03959 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 |
852 | Malaria 💬 14 genes, 25 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
853 | Malaria 💬 14 genes, 25 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
854 | Malaria 💬 14 genes, 25 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
855 | Malaria 💬 14 genes, 25 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
856 | Malaria 💬 14 genes, 25 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
857 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
858 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
859 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
860 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
861 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
862 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
863 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
864 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
865 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
866 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
867 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
868 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
869 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
870 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
871 | Measles 💬 36 genes, 37 drugs (DrugBank) and 49 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D05092 D05092 💬 |
Muromonab | 060 [3] 60, 96, 97 💬 |
872 | Measles 💬 36 genes, 37 drugs (DrugBank) and 49 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D06314 D06314 💬 |
Visilizumab | 096 [2] 96, 97 💬 |
873 | Measles 💬 36 genes, 37 drugs (DrugBank) and 49 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 |
874 | Measles 💬 36 genes, 37 drugs (DrugBank) and 49 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 |
875 | Measles 💬 36 genes, 37 drugs (DrugBank) and 49 diseases |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
876 | Measles 💬 36 genes, 37 drugs (DrugBank) and 49 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
877 | Measles 💬 36 genes, 37 drugs (DrugBank) and 49 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
878 | Measles 💬 36 genes, 37 drugs (DrugBank) and 49 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
879 | Measles 💬 36 genes, 37 drugs (DrugBank) and 49 diseases |
JAK1 [3] JAK1, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
880 | Melanogenesis 💬 5 genes, 11 drugs (DrugBank) and 25 diseases |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
881 | Melanoma 💬 13 genes, 23 drugs (DrugBank) and 34 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
882 | Melanoma 💬 13 genes, 23 drugs (DrugBank) and 34 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
883 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
884 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D01207 D01207 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
885 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D05259 D05259 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
886 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D05261 D05261 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
887 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
DHFR [2] DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
888 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
DHFR [2] DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
889 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
FDPS [1] FDPS 💬 |
D00942 D00942 💬 |
Risedronic acid | 046 [8] 46, 50, 66, 93, 95, 96, 113, 274 💬 |
890 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
FDPS [1] FDPS 💬 |
D03234 D03234 💬 |
Risedronic acid | 046 [8] 46, 50, 66, 93, 95, 96, 113, 274 💬 |
891 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
FDPS [1] FDPS 💬 |
D08484 D08484 💬 |
Risedronic acid | 046 [8] 46, 50, 66, 93, 95, 96, 113, 274 💬 |
892 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
FDPS [1] FDPS 💬 |
D01968 D01968 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
893 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
FDPS [1] FDPS 💬 |
D06378 D06378 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
894 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
FDPS [1] FDPS 💬 |
D06379 D06379 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
895 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
FDPS [1] FDPS 💬 |
D08689 D08689 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
896 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
HMGCR [1] HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
897 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
HMGCR [1] HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
898 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
HMGCR [1] HMGCR 💬 |
D00893 D00893 💬 |
Pravastatin | 013 [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
899 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
HMGCR [1] HMGCR 💬 |
D08410 D08410 💬 |
Pravastatin | 013 [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
900 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
HMGCR [1] HMGCR 💬 |
D01915 D01915 💬 |
Rosuvastatin | 006 [11] 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
901 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
HMGCR [1] HMGCR 💬 |
D08492 D08492 💬 |
Rosuvastatin | 006 [11] 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
902 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
HPRT1 [1] HPRT1 💬 |
D00161 D00161 💬 |
Mercaptopurine | 096 [3] 96, 97, 164 💬 |
903 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
HPRT1 [1] HPRT1 💬 |
D04931 D04931 💬 |
Mercaptopurine | 096 [3] 96, 97, 164 💬 |
904 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D00752 D00752 💬 |
Mycophenolate mofetil | 002 [32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
905 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05094 D05094 💬 |
Mycophenolate mofetil | 002 [32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
906 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05095 D05095 💬 |
Mycophenolate mofetil | 002 [32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
907 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05096 D05096 💬 |
Mycophenolic acid | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 |
908 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
NQO1 [2] NQO1, VKORC1 💬 |
D00564 D00564 💬 |
Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
909 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
NQO1 [2] NQO1, VKORC1 💬 |
D01280 D01280 💬 |
Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
910 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
NQO1 [2] NQO1, VKORC1 💬 |
D08682 D08682 💬 |
Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
911 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PDE1B [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
912 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PDE1B [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
913 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
914 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
915 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
RRM1 [1] RRM1 💬 |
D03546 D03546 💬 |
Clofarabine | 019 [9] 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 |
916 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
RRM1 [1] RRM1 💬 |
D01907 D01907 💬 |
Fludarabine | 013 [18] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬 |
917 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
RRM1 [1] RRM1 💬 |
D07966 D07966 💬 |
Fludarabine | 013 [18] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬 |
918 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
XDH [1] XDH 💬 |
D00224 D00224 💬 |
Allopurinol | 006 [6] 6 , 46, 57, 66, 96, 97 💬 |
919 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
HDAC1 [4] HDAC1, HDAC2, HDAC4, HDAC5 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
920 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
921 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
922 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
923 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
924 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 37 diseases |
VDR [1] VDR 💬 |
D01518 D01518 💬 |
Alfacalcidol | 041 [6] 41, 46, 49, 50, 96, 235 💬 |
925 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 37 diseases |
VDR [1] VDR 💬 |
D00129 D00129 💬 |
Calcitriol | 037 [8] 37, 46, 49, 66, 96, 158, 235, 326 💬 |
926 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 37 diseases |
VDR [1] VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 [23] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 162, 202, 228, 271, 298, 299 💬 |
927 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 37 diseases |
VDR [1] VDR 💬 |
D00187 D00187 💬 |
Ergocalciferol | 046 [5] 46, 84, 96, 97, 299 💬 |
928 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
ADORA1 [9] ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
929 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
ADORA1 [9] ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
930 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
931 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00696 D00696 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
932 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D05028 D05028 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
933 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
OPRM1 [1] OPRM1 💬 |
D02095 D02095 💬 |
Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
934 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
OPRM1 [1] OPRM1 💬 |
D05113 D05113 💬 |
Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
935 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
936 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
937 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
938 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
939 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
940 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
941 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
942 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
943 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
944 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
945 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
946 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
HLA-A [5] HLA-A, HLA-B, HLA-C, HLA-E, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
947 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 |
948 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 |
949 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
ITGAL [1] ITGAL 💬 |
D03959 D03959 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 |
950 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
951 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
952 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
953 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
954 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
955 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
956 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
957 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 |
958 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 |
959 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
960 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
961 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
JAK1 [4] JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
962 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
963 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
964 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
965 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
966 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
967 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADORA1 [2] ADORA1, ADORA2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
968 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADORA1 [2] ADORA1, ADORA2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
969 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D00095 D00095 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
970 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D00996 D00996 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
971 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D02149 D02149 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
972 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
973 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
974 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
CNR1 [2] CNR1, CNR2 💬 |
D10915 D10915 💬 |
Cannabidiol | 002 [19] 2 , 6 , 8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 |
975 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
CNR1 [2] CNR1, CNR2 💬 |
D00306 D00306 💬 |
Dronabinol | 002 [7] 2 , 8 , 13, 46, 96, 271, 298 💬 |
976 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
977 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00696 D00696 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
978 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D05028 D05028 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
979 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GHR [1] GHR 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
980 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GHR [1] GHR 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
981 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [20] 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
982 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GLP2R [1] GLP2R 💬 |
D06053 D06053 💬 |
Teduglutide | 096 [1] 96 💬 |
983 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
984 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
985 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
986 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
HRH1 [1] HRH1 💬 |
D00300 D00300 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
987 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
HRH1 [1] HRH1 💬 |
D00669 D00669 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
988 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
HRH1 [1] HRH1 💬 |
D02419 D02419 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
989 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
HRH1 [1] HRH1 💬 |
D03285 D03285 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
990 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
HRH1 [1] HRH1 💬 |
D03360 D03360 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
991 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
HRH1 [1] HRH1 💬 |
D03854 D03854 💬 |
Diphenhydramine | 011 [8] 11, 49, 51, 70, 86, 96, 222, 256 💬 |
992 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
HRH1 [1] HRH1 💬 |
D00480 D00480 💬 |
Promethazine | 096 [1] 96 💬 |
993 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
HRH1 [1] HRH1 💬 |
D00494 D00494 💬 |
Promethazine | 096 [1] 96 💬 |
994 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
HRH1 [1] HRH1 💬 |
D01242 D01242 💬 |
Promethazine | 096 [1] 96 💬 |
995 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
HRH1 [1] HRH1 💬 |
D03290 D03290 💬 |
Promethazine | 096 [1] 96 💬 |
996 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
HTR4 [1] HTR4 💬 |
D08236 D08236 💬 |
Mosapride | 096 [1] 96 💬 |
997 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
HTR4 [1] HTR4 💬 |
D09205 D09205 💬 |
Prucalopride | 013 [3] 13, 51, 96 💬 |
998 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00244 D00244 💬 |
Betamethasone | 002 [6] 2 , 28, 46, 90, 96, 235 💬 |
999 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00972 D00972 💬 |
Betamethasone | 002 [6] 2 , 28, 46, 90, 96, 235 💬 |
1000 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D01357 D01357 💬 |
Betamethasone | 002 [6] 2 , 28, 46, 90, 96, 235 💬 |
1001 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D01402 D01402 💬 |
Betamethasone | 002 [6] 2 , 28, 46, 90, 96, 235 💬 |
1002 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D01637 D01637 💬 |
Betamethasone | 002 [6] 2 , 28, 46, 90, 96, 235 💬 |
1003 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D02032 D02032 💬 |
Betamethasone | 002 [6] 2 , 28, 46, 90, 96, 235 💬 |
1004 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D02286 D02286 💬 |
Betamethasone | 002 [6] 2 , 28, 46, 90, 96, 235 💬 |
1005 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00246 D00246 💬 |
Budesonide | 066 [9] 66, 93, 94, 95, 96, 97, 98, 228, 299 💬 |
1006 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00292 D00292 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬 |
1007 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00975 D00975 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬 |
1008 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D01510 D01510 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬 |
1009 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D01615 D01615 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬 |
1010 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D01632 D01632 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬 |
1011 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D01948 D01948 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬 |
1012 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D02174 D02174 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬 |
1013 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D02591 D02591 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬 |
1014 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D02592 D02592 💬 |
Dexamethasone | 013 [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬 |
1015 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00407 D00407 💬 |
Methylprednisolone | 002 [44] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
1016 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00751 D00751 💬 |
Methylprednisolone | 002 [44] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
1017 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00979 D00979 💬 |
Methylprednisolone | 002 [44] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
1018 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D05000 D05000 💬 |
Methylprednisolone | 002 [44] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
1019 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D05001 D05001 💬 |
Methylprednisolone | 002 [44] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
1020 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D05002 D05002 💬 |
Methylprednisolone | 002 [44] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
1021 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00472 D00472 💬 |
Prednisolone | 011 [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 |
1022 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00980 D00980 💬 |
Prednisolone | 011 [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 |
1023 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00981 D00981 💬 |
Prednisolone | 011 [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 |
1024 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00982 D00982 💬 |
Prednisolone | 011 [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 |
1025 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D01239 D01239 💬 |
Prednisolone | 011 [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 |
1026 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D01998 D01998 💬 |
Prednisolone | 011 [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 |
1027 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D02156 D02156 💬 |
Prednisolone | 011 [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 |
1028 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D03301 D03301 💬 |
Prednisolone | 011 [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 |
1029 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00473 D00473 💬 |
Prednisone | 002 [47] 2 , 6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 93, 95, 96, 97, 113, 127, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬 |
1030 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00385 D00385 💬 |
Triamcinolone | 035 [8] 35, 46, 56, 70, 90, 96, 226, 298 💬 |
1031 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00983 D00983 💬 |
Triamcinolone | 035 [8] 35, 46, 56, 70, 90, 96, 226, 298 💬 |
1032 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00984 D00984 💬 |
Triamcinolone | 035 [8] 35, 46, 56, 70, 90, 96, 226, 298 💬 |
1033 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D00985 D00985 💬 |
Triamcinolone | 035 [8] 35, 46, 56, 70, 90, 96, 226, 298 💬 |
1034 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 [1] NR3C1 💬 |
D06216 D06216 💬 |
Triamcinolone | 035 [8] 35, 46, 56, 70, 90, 96, 226, 298 💬 |
1035 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
OPRD1 [3] OPRD1, OPRK1, OPRM1 💬 |
D02095 D02095 💬 |
Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
1036 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
OPRD1 [3] OPRD1, OPRK1, OPRM1 💬 |
D05113 D05113 💬 |
Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
1037 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
S1PR1 [5] S1PR1, S1PR2, S1PR3, S1PR4, S1PR5 💬 |
D10930 D10930 💬 |
Etrasimod | 096 [2] 96, 97 💬 |
1038 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
S1PR1 [5] S1PR1, S1PR2, S1PR3, S1PR4, S1PR5 💬 |
D10968 D10968 💬 |
Ozanimod | 013 [3] 13, 96, 97 💬 |
1039 | Neutrophil extracellular trap formation 💬 32 genes, 27 drugs (DrugBank) and 56 diseases |
ELANE [1] ELANE 💬 |
D03788 D03788 💬 |
Sivelestat | 013 [3] 13, 85, 96 💬 |
1040 | Neutrophil extracellular trap formation 💬 32 genes, 27 drugs (DrugBank) and 56 diseases |
HDAC1 [11] HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
1041 | Neutrophil extracellular trap formation 💬 32 genes, 27 drugs (DrugBank) and 56 diseases |
ITGAL [1] ITGAL 💬 |
D03959 D03959 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 |
1042 | Neutrophil extracellular trap formation 💬 32 genes, 27 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
1043 | Neutrophil extracellular trap formation 💬 32 genes, 27 drugs (DrugBank) and 56 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1044 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
1045 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
1046 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
1047 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
1048 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
1049 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
1050 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1051 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
TNFSF11 [1] TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 [7] 46, 50, 93, 95, 96, 274, 299 💬 |
1052 | Nicotine addiction 💬 30 genes, 32 drugs (DrugBank) and 40 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
1053 | Nicotine addiction 💬 30 genes, 32 drugs (DrugBank) and 40 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00696 D00696 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
1054 | Nicotine addiction 💬 30 genes, 32 drugs (DrugBank) and 40 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D05028 D05028 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
1055 | Nicotine addiction 💬 30 genes, 32 drugs (DrugBank) and 40 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1056 | Nicotine addiction 💬 30 genes, 32 drugs (DrugBank) and 40 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1057 | Nicotine addiction 💬 30 genes, 32 drugs (DrugBank) and 40 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1058 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 |
1059 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 |
1060 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
1061 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
1062 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
JAK1 [2] JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
1063 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
1064 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
1065 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
1066 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
1067 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1068 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
1069 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
1070 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
1071 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
1072 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
1073 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
1074 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1075 | Non-small cell lung cancer 💬 18 genes, 27 drugs (DrugBank) and 42 diseases |
JAK3 [1] JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
1076 | Notch signaling pathway 💬 7 genes, 3 drugs (DrugBank) and 5 diseases |
HDAC1 [2] HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
1077 | Olfactory transduction 💬 4 genes, 3 drugs (DrugBank) and 12 diseases |
PDE1B [2] PDE1B, PDE2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1078 | Olfactory transduction 💬 4 genes, 3 drugs (DrugBank) and 12 diseases |
PDE1B [2] PDE1B, PDE2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1079 | One carbon pool by folate 💬 3 genes, 3 drugs (DrugBank) and 36 diseases |
DHFR [2] DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
1080 | One carbon pool by folate 💬 3 genes, 3 drugs (DrugBank) and 36 diseases |
DHFR [2] DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 [35] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
1081 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
AR [1] AR 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
1082 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
1083 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
1084 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1085 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1086 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 |
1087 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 |
1088 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
1089 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
1090 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
JAK1 [2] JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
1091 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
1092 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
1093 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1094 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1095 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
1096 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
1097 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
1098 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
1099 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1100 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
TNFSF11 [1] TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 [7] 46, 50, 93, 95, 96, 274, 299 💬 |
1101 | Ovarian steroidogenesis 💬 6 genes, 34 drugs (DrugBank) and 47 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
1102 | Ovarian steroidogenesis 💬 6 genes, 34 drugs (DrugBank) and 47 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
1103 | Ovarian steroidogenesis 💬 6 genes, 34 drugs (DrugBank) and 47 diseases |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
1104 | Ovarian steroidogenesis 💬 6 genes, 34 drugs (DrugBank) and 47 diseases |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
1105 | Ovarian steroidogenesis 💬 6 genes, 34 drugs (DrugBank) and 47 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
1106 | Ovarian steroidogenesis 💬 6 genes, 34 drugs (DrugBank) and 47 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
1107 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 23 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
1108 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 23 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D01207 D01207 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
1109 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 23 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D05259 D05259 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
1110 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 23 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
D05261 D05261 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
1111 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
1112 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
1113 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1114 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1115 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
1116 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
1117 | Pancreatic cancer 💬 16 genes, 29 drugs (DrugBank) and 64 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
1118 | Pancreatic cancer 💬 16 genes, 29 drugs (DrugBank) and 64 diseases |
JAK1 [1] JAK1 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
1119 | Pancreatic cancer 💬 16 genes, 29 drugs (DrugBank) and 64 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
1120 | Pancreatic cancer 💬 16 genes, 29 drugs (DrugBank) and 64 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
1121 | Pancreatic cancer 💬 16 genes, 29 drugs (DrugBank) and 64 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1122 | Parathyroid hormone synthesis, secretion and action 💬 19 genes, 40 drugs (DrugBank) and 58 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1123 | Parathyroid hormone synthesis, secretion and action 💬 19 genes, 40 drugs (DrugBank) and 58 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1124 | Parathyroid hormone synthesis, secretion and action 💬 19 genes, 40 drugs (DrugBank) and 58 diseases |
TNFSF11 [1] TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 [7] 46, 50, 93, 95, 96, 274, 299 💬 |
1125 | Parathyroid hormone synthesis, secretion and action 💬 19 genes, 40 drugs (DrugBank) and 58 diseases |
VDR [1] VDR 💬 |
D01518 D01518 💬 |
Alfacalcidol | 041 [6] 41, 46, 49, 50, 96, 235 💬 |
1126 | Parathyroid hormone synthesis, secretion and action 💬 19 genes, 40 drugs (DrugBank) and 58 diseases |
VDR [1] VDR 💬 |
D00129 D00129 💬 |
Calcitriol | 037 [8] 37, 46, 49, 66, 96, 158, 235, 326 💬 |
1127 | Parathyroid hormone synthesis, secretion and action 💬 19 genes, 40 drugs (DrugBank) and 58 diseases |
VDR [1] VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 [23] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 162, 202, 228, 271, 298, 299 💬 |
1128 | Parathyroid hormone synthesis, secretion and action 💬 19 genes, 40 drugs (DrugBank) and 58 diseases |
VDR [1] VDR 💬 |
D00187 D00187 💬 |
Ergocalciferol | 046 [5] 46, 84, 96, 97, 299 💬 |
1129 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
ADORA2A [1] ADORA2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1130 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
ADORA2A [1] ADORA2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1131 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
SLC6A3 [1] SLC6A3 💬 |
D00817 D00817 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
1132 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
SLC6A3 [1] SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
1133 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
SLC6A3 [1] SLC6A3 💬 |
D07938 D07938 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
1134 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
1135 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
1136 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
1137 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
1138 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1139 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
1140 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
1141 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
AR [3] AR, ESR1, ESR2 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
1142 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
CSF2RA [1] CSF2RA 💬 |
D05803 D05803 💬 |
Sargramostim | 006 [7] 6 , 28, 60, 62, 96, 229, 285 💬 |
1143 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
CSF3R [1] CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 [33] 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
1144 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
EPOR [1] EPOR 💬 |
D03231 D03231 💬 |
Erythropoietin | 002 [10] 2 , 6 , 13, 18, 22, 46, 47, 70, 95, 96 💬 |
1145 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
HDAC1 [2] HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
1146 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 |
1147 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 |
1148 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
1149 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
1150 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
IL12A [3] IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
1151 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
IL23A [1] IL23A 💬 |
D10912 D10912 💬 |
Brazikumab | 096 [2] 96, 97 💬 |
1152 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
IL23A [1] IL23A 💬 |
D10438 D10438 💬 |
Guselkumab | 037 [4] 37, 41, 96, 97 💬 |
1153 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
IL23A [1] IL23A 💬 |
D11123 D11123 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 |
1154 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
IL23A [1] IL23A 💬 |
D11052 D11052 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 |
1155 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
1156 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
1157 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
1158 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
JAK1 [3] JAK1, JAK2, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
1159 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
1160 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
1161 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1162 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
NQO1 [1] NQO1 💬 |
D00564 D00564 💬 |
Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
1163 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
NQO1 [1] NQO1 💬 |
D01280 D01280 💬 |
Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
1164 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
NQO1 [1] NQO1 💬 |
D08682 D08682 💬 |
Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
1165 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
1166 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
1167 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
1168 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
1169 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
RARA [1] RARA 💬 |
D01418 D01418 💬 |
Tamibarotene | 026 [2] 26, 96 💬 |
1170 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
1171 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
1172 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
GRIN1 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1173 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
GRIN1 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1174 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
GRIN1 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1175 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
1176 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1177 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1178 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1179 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
1180 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
1181 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
SLC6A3 [1] SLC6A3 💬 |
D00817 D00817 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
1182 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
SLC6A3 [1] SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
1183 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
SLC6A3 [1] SLC6A3 💬 |
D07938 D07938 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
1184 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
1185 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
1186 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
1187 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
1188 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1189 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D05092 D05092 💬 |
Muromonab | 060 [3] 60, 96, 97 💬 |
1190 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D06314 D06314 💬 |
Visilizumab | 096 [2] 96, 97 💬 |
1191 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
1192 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
1193 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
JAK1 [2] JAK1, JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
1194 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
1195 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1196 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
PDCD1 [1] PDCD1 💬 |
D10316 D10316 💬 |
Nivolumab | 013 [12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬 |
1197 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1198 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1199 | Peroxisome 💬 2 genes, 3 drugs (DrugBank) and 9 diseases |
XDH [1] XDH 💬 |
D00224 D00224 💬 |
Allopurinol | 006 [6] 6 , 46, 57, 66, 96, 97 💬 |
1200 | Pertussis 💬 16 genes, 32 drugs (DrugBank) and 65 diseases |
IL12A [3] IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
1201 | Pertussis 💬 16 genes, 32 drugs (DrugBank) and 65 diseases |
IL23A [1] IL23A 💬 |
D10912 D10912 💬 |
Brazikumab | 096 [2] 96, 97 💬 |
1202 | Pertussis 💬 16 genes, 32 drugs (DrugBank) and 65 diseases |
IL23A [1] IL23A 💬 |
D10438 D10438 💬 |
Guselkumab | 037 [4] 37, 41, 96, 97 💬 |
1203 | Pertussis 💬 16 genes, 32 drugs (DrugBank) and 65 diseases |
IL23A [1] IL23A 💬 |
D11123 D11123 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 |
1204 | Pertussis 💬 16 genes, 32 drugs (DrugBank) and 65 diseases |
IL23A [1] IL23A 💬 |
D11052 D11052 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 |
1205 | Pertussis 💬 16 genes, 32 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
1206 | Pertussis 💬 16 genes, 32 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
1207 | Pertussis 💬 16 genes, 32 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
1208 | Pertussis 💬 16 genes, 32 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
1209 | Pertussis 💬 16 genes, 32 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1210 | Phagosome 💬 31 genes, 8 drugs (DrugBank) and 18 diseases |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
1211 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
1212 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
1213 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
1214 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
1215 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
1216 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
1217 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1218 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
CSF3R [1] CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 [33] 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
1219 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
EPOR [1] EPOR 💬 |
D03231 D03231 💬 |
Erythropoietin | 002 [10] 2 , 6 , 13, 18, 22, 46, 47, 70, 95, 96 💬 |
1220 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [20] 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
1221 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
GHR [2] GHR, IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
1222 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
GHR [2] GHR, IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
1223 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 |
1224 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 |
1225 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
1226 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
1227 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
1228 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
ITGA4 [1] ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 [6] 13, 15, 25, 46, 63, 96 💬 |
1229 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
D10540 D10540 💬 |
Abrilumab | 096 [2] 96, 97 💬 |
1230 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 |
1231 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
ITGB7 [1] ITGB7 💬 |
D09901 D09901 💬 |
Etrolizumab | 096 [2] 96, 97 💬 |
1232 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
1233 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
1234 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
JAK1 [3] JAK1, JAK2, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
1235 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
1236 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
1237 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1238 | Platelet activation 💬 22 genes, 44 drugs (DrugBank) and 47 diseases |
PTGS1 [1] PTGS1 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
1239 | Platelet activation 💬 22 genes, 44 drugs (DrugBank) and 47 diseases |
PTGS1 [1] PTGS1 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
1240 | PPAR signaling pathway 💬 10 genes, 12 drugs (DrugBank) and 30 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
1241 | PPAR signaling pathway 💬 10 genes, 12 drugs (DrugBank) and 30 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
1242 | Primary immunodeficiency 💬 10 genes, 17 drugs (DrugBank) and 22 diseases |
CD3D [2] CD3D, CD3E 💬 |
D05092 D05092 💬 |
Muromonab | 060 [3] 60, 96, 97 💬 |
1243 | Primary immunodeficiency 💬 10 genes, 17 drugs (DrugBank) and 22 diseases |
CD3D [2] CD3D, CD3E 💬 |
D06314 D06314 💬 |
Visilizumab | 096 [2] 96, 97 💬 |
1244 | Primary immunodeficiency 💬 10 genes, 17 drugs (DrugBank) and 22 diseases |
IL2RG [1] IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
1245 | Primary immunodeficiency 💬 10 genes, 17 drugs (DrugBank) and 22 diseases |
JAK3 [1] JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
1246 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
1247 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
1248 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1249 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1250 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1251 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1252 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1253 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
1254 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
1255 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
1256 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
1257 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1258 | Progesterone-mediated oocyte maturation 💬 14 genes, 32 drugs (DrugBank) and 37 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
1259 | Progesterone-mediated oocyte maturation 💬 14 genes, 32 drugs (DrugBank) and 37 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
1260 | Progesterone-mediated oocyte maturation 💬 14 genes, 32 drugs (DrugBank) and 37 diseases |
PDE3B [1] PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1261 | Progesterone-mediated oocyte maturation 💬 14 genes, 32 drugs (DrugBank) and 37 diseases |
PDE3B [1] PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1262 | Prolactin signaling pathway 💬 18 genes, 33 drugs (DrugBank) and 48 diseases |
ESR1 [2] ESR1, ESR2 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
1263 | Prolactin signaling pathway 💬 18 genes, 33 drugs (DrugBank) and 48 diseases |
JAK2 [1] JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
1264 | Prolactin signaling pathway 💬 18 genes, 33 drugs (DrugBank) and 48 diseases |
TNFSF11 [1] TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 [7] 46, 50, 93, 95, 96, 274, 299 💬 |
1265 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
AR [1] AR 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
1266 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
1267 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
1268 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
1269 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1270 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
ESR1 [1] ESR1 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
1271 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
1272 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
1273 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
IL12B [1] IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
1274 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
1275 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1276 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
1277 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
1278 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
1279 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
1280 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1281 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
HPRT1 [1] HPRT1 💬 |
D00161 D00161 💬 |
Mercaptopurine | 096 [3] 96, 97, 164 💬 |
1282 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
HPRT1 [1] HPRT1 💬 |
D04931 D04931 💬 |
Mercaptopurine | 096 [3] 96, 97, 164 💬 |
1283 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D00752 D00752 💬 |
Mycophenolate mofetil | 002 [32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
1284 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05094 D05094 💬 |
Mycophenolate mofetil | 002 [32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
1285 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05095 D05095 💬 |
Mycophenolate mofetil | 002 [32] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
1286 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05096 D05096 💬 |
Mycophenolic acid | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 |
1287 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
PDE1B [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1288 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
PDE1B [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1289 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
RRM1 [1] RRM1 💬 |
D03546 D03546 💬 |
Clofarabine | 019 [9] 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 |
1290 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
RRM1 [1] RRM1 💬 |
D01907 D01907 💬 |
Fludarabine | 013 [18] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬 |
1291 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
RRM1 [1] RRM1 💬 |
D07966 D07966 💬 |
Fludarabine | 013 [18] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬 |
1292 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
XDH [1] XDH 💬 |
D00224 D00224 💬 |
Allopurinol | 006 [6] 6 , 46, 57, 66, 96, 97 💬 |
1293 | Pyrimidine metabolism 💬 4 genes, 8 drugs (DrugBank) and 32 diseases |
RRM1 [1] RRM1 💬 |
D03546 D03546 💬 |
Clofarabine | 019 [9] 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 |
1294 | Pyrimidine metabolism 💬 4 genes, 8 drugs (DrugBank) and 32 diseases |
RRM1 [1] RRM1 💬 |
D01907 D01907 💬 |
Fludarabine | 013 [18] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬 |
1295 | Pyrimidine metabolism 💬 4 genes, 8 drugs (DrugBank) and 32 diseases |
RRM1 [1] RRM1 💬 |
D07966 D07966 💬 |
Fludarabine | 013 [18] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬 |
1296 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
ADORA2A [1] ADORA2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1297 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
ADORA2A [1] ADORA2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1298 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
CNR1 [1] CNR1 💬 |
D10915 D10915 💬 |
Cannabidiol | 002 [19] 2 , 6 , 8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 |
1299 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
CNR1 [1] CNR1 💬 |
D00306 D00306 💬 |
Dronabinol | 002 [7] 2 , 8 , 13, 46, 96, 271, 298 💬 |
1300 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1301 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1302 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1303 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
1304 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
1305 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
1306 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
1307 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
ITGAL [1] ITGAL 💬 |
D03959 D03959 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 |
1308 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
1309 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1310 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1311 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1312 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
1313 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
1314 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
1315 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
1316 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
1317 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
ITGA4 [1] ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 [6] 13, 15, 25, 46, 63, 96 💬 |
1318 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
D10540 D10540 💬 |
Abrilumab | 096 [2] 96, 97 💬 |
1319 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 |
1320 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
ITGAL [1] ITGAL 💬 |
D03959 D03959 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 |
1321 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
ITGB7 [1] ITGB7 💬 |
D09901 D09901 💬 |
Etrolizumab | 096 [2] 96, 97 💬 |
1322 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
ADORA1 [2] ADORA1, PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1323 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
ADORA1 [2] ADORA1, PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1324 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D00095 D00095 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
1325 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D00996 D00996 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
1326 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D02149 D02149 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
1327 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
1328 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
1329 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
1330 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
1331 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ACE [1] ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 [8] 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
1332 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ADORA1 [4] ADORA1, PDE1B, PDE3A, PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1333 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ADORA1 [4] ADORA1, PDE1B, PDE3A, PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1334 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D00095 D00095 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
1335 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D00996 D00996 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
1336 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D02149 D02149 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
1337 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
1338 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
1339 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
1340 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
1341 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1342 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1343 | Renin-angiotensin system 💬 6 genes, 21 drugs (DrugBank) and 32 diseases |
ACE [1] ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 [8] 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
1344 | Renin-angiotensin system 💬 6 genes, 21 drugs (DrugBank) and 32 diseases |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
1345 | Renin-angiotensin system 💬 6 genes, 21 drugs (DrugBank) and 32 diseases |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
1346 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
1347 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
1348 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
CNR1 [1] CNR1 💬 |
D10915 D10915 💬 |
Cannabidiol | 002 [19] 2 , 6 , 8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 |
1349 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
CNR1 [1] CNR1 💬 |
D00306 D00306 💬 |
Dronabinol | 002 [7] 2 , 8 , 13, 46, 96, 271, 298 💬 |
1350 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
1351 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00696 D00696 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
1352 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D05028 D05028 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
1353 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
1354 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
1355 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
1356 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
CTLA4 [1] CTLA4 💬 |
D06657 D06657 💬 |
Tremelimumab | 096 [1] 96 💬 |
1357 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
1358 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
IL23A [1] IL23A 💬 |
D10912 D10912 💬 |
Brazikumab | 096 [2] 96, 97 💬 |
1359 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
IL23A [1] IL23A 💬 |
D10438 D10438 💬 |
Guselkumab | 037 [4] 37, 41, 96, 97 💬 |
1360 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
IL23A [1] IL23A 💬 |
D11123 D11123 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 |
1361 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
IL23A [1] IL23A 💬 |
D11052 D11052 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 |
1362 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
IL23A [1] IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
1363 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
ITGAL [1] ITGAL 💬 |
D03959 D03959 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 |
1364 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
1365 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
1366 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
1367 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
1368 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1369 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
TNFSF11 [1] TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 [7] 46, 50, 93, 95, 96, 274, 299 💬 |
1370 | RIG-I-like receptor signaling pathway 💬 21 genes, 17 drugs (DrugBank) and 53 diseases |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
1371 | RIG-I-like receptor signaling pathway 💬 21 genes, 17 drugs (DrugBank) and 53 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
1372 | RIG-I-like receptor signaling pathway 💬 21 genes, 17 drugs (DrugBank) and 53 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
1373 | RIG-I-like receptor signaling pathway 💬 21 genes, 17 drugs (DrugBank) and 53 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
1374 | RIG-I-like receptor signaling pathway 💬 21 genes, 17 drugs (DrugBank) and 53 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
1375 | RIG-I-like receptor signaling pathway 💬 21 genes, 17 drugs (DrugBank) and 53 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1376 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
D00095 D00095 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
1377 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
D00996 D00996 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
1378 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
D02149 D02149 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
1379 | Salmonella infection 💬 25 genes, 32 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
1380 | Salmonella infection 💬 25 genes, 32 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
1381 | Salmonella infection 💬 25 genes, 32 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
1382 | Salmonella infection 💬 25 genes, 32 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
1383 | Salmonella infection 💬 25 genes, 32 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1384 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
1385 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
1386 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬 |
D00550 D00550 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
1387 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬 |
D00696 D00696 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
1388 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬 |
D05028 D05028 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
1389 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
HTR4 [1] HTR4 💬 |
D08236 D08236 💬 |
Mosapride | 096 [1] 96 💬 |
1390 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
HTR4 [1] HTR4 💬 |
D09205 D09205 💬 |
Prucalopride | 013 [3] 13, 51, 96 💬 |
1391 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
1392 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
1393 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
1394 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1395 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
1396 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
1397 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
1398 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
1399 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1400 | Signaling pathways regulating pluripotency of stem cells 💬 20 genes, 24 drugs (DrugBank) and 43 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
1401 | Signaling pathways regulating pluripotency of stem cells 💬 20 genes, 24 drugs (DrugBank) and 43 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
1402 | Signaling pathways regulating pluripotency of stem cells 💬 20 genes, 24 drugs (DrugBank) and 43 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
1403 | Signaling pathways regulating pluripotency of stem cells 💬 20 genes, 24 drugs (DrugBank) and 43 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
1404 | Signaling pathways regulating pluripotency of stem cells 💬 20 genes, 24 drugs (DrugBank) and 43 diseases |
JAK1 [3] JAK1, JAK2, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
1405 | Small cell lung cancer 💬 11 genes, 35 drugs (DrugBank) and 51 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
1406 | Small cell lung cancer 💬 11 genes, 35 drugs (DrugBank) and 51 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
1407 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
ADORA1 [1] ADORA1 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1408 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
ADORA1 [1] ADORA1 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1409 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
OPRD1 [1] OPRD1 💬 |
D02095 D02095 💬 |
Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
1410 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
OPRD1 [1] OPRD1 💬 |
D05113 D05113 💬 |
Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
1411 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
S1PR1 [5] S1PR1, S1PR2, S1PR3, S1PR4, S1PR5 💬 |
D10930 D10930 💬 |
Etrasimod | 096 [2] 96, 97 💬 |
1412 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
S1PR1 [5] S1PR1, S1PR2, S1PR3, S1PR4, S1PR5 💬 |
D10968 D10968 💬 |
Ozanimod | 013 [3] 13, 96, 97 💬 |
1413 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
1414 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
1415 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
1416 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
1417 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1418 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1419 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1420 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1421 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
1422 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1423 | Staphylococcus aureus infection 💬 24 genes, 15 drugs (DrugBank) and 32 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
1424 | Staphylococcus aureus infection 💬 24 genes, 15 drugs (DrugBank) and 32 diseases |
ITGAL [1] ITGAL 💬 |
D03959 D03959 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 |
1425 | Synaptic vesicle cycle 💬 7 genes, 29 drugs (DrugBank) and 37 diseases |
SLC6A2 [2] SLC6A2, SLC6A3 💬 |
D00817 D00817 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
1426 | Synaptic vesicle cycle 💬 7 genes, 29 drugs (DrugBank) and 37 diseases |
SLC6A2 [2] SLC6A2, SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
1427 | Synaptic vesicle cycle 💬 7 genes, 29 drugs (DrugBank) and 37 diseases |
SLC6A2 [2] SLC6A2, SLC6A3 💬 |
D07938 D07938 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
1428 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
1429 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
ELANE [1] ELANE 💬 |
D03788 D03788 💬 |
Sivelestat | 013 [3] 13, 85, 96 💬 |
1430 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1431 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1432 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
1433 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
1434 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
1435 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
1436 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
1437 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
1438 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1439 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D05092 D05092 💬 |
Muromonab | 060 [3] 60, 96, 97 💬 |
1440 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D06314 D06314 💬 |
Visilizumab | 096 [2] 96, 97 💬 |
1441 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
CTLA4 [1] CTLA4 💬 |
D06657 D06657 💬 |
Tremelimumab | 096 [1] 96 💬 |
1442 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
PDCD1 [1] PDCD1 💬 |
D10316 D10316 💬 |
Nivolumab | 013 [12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬 |
1443 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1444 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1445 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
1446 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
1447 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
1448 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
1449 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1450 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
CACNA1C [1] CACNA1C 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
1451 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
CACNA1C [1] CACNA1C 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
1452 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00550 D00550 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
1453 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00696 D00696 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
1454 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D05028 D05028 💬 |
Midazolam | 002 [11] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 |
1455 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
PDE1B [1] PDE1B 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1456 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
PDE1B [1] PDE1B 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1457 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D01450 D01450 💬 |
Bupivacaine | 046 [8] 46, 51, 53, 70, 96, 168, 226, 298 💬 |
1458 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D07552 D07552 💬 |
Bupivacaine | 046 [8] 46, 51, 53, 70, 96, 168, 226, 298 💬 |
1459 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
FDPS [1] FDPS 💬 |
D00942 D00942 💬 |
Risedronic acid | 046 [8] 46, 50, 66, 93, 95, 96, 113, 274 💬 |
1460 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
FDPS [1] FDPS 💬 |
D03234 D03234 💬 |
Risedronic acid | 046 [8] 46, 50, 66, 93, 95, 96, 113, 274 💬 |
1461 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
FDPS [1] FDPS 💬 |
D08484 D08484 💬 |
Risedronic acid | 046 [8] 46, 50, 66, 93, 95, 96, 113, 274 💬 |
1462 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
FDPS [1] FDPS 💬 |
D01968 D01968 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
1463 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
FDPS [1] FDPS 💬 |
D06378 D06378 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
1464 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
FDPS [1] FDPS 💬 |
D06379 D06379 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
1465 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
FDPS [1] FDPS 💬 |
D08689 D08689 💬 |
Zoledronic acid | 006 [10] 6 , 13, 46, 65, 93, 95, 96, 274, 299, 333 💬 |
1466 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
HMGCR [1] HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
1467 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
HMGCR [1] HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
1468 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
HMGCR [1] HMGCR 💬 |
D00893 D00893 💬 |
Pravastatin | 013 [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
1469 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
HMGCR [1] HMGCR 💬 |
D08410 D08410 💬 |
Pravastatin | 013 [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
1470 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
HMGCR [1] HMGCR 💬 |
D01915 D01915 💬 |
Rosuvastatin | 006 [11] 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
1471 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
HMGCR [1] HMGCR 💬 |
D08492 D08492 💬 |
Rosuvastatin | 006 [11] 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
1472 | TGF-beta signaling pathway 💬 11 genes, 20 drugs (DrugBank) and 54 diseases |
SMAD7 [1] SMAD7 💬 |
D10956 D10956 💬 |
Mongersen | 096 [2] 96, 97 💬 |
1473 | TGF-beta signaling pathway 💬 11 genes, 20 drugs (DrugBank) and 54 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
1474 | TGF-beta signaling pathway 💬 11 genes, 20 drugs (DrugBank) and 54 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
1475 | TGF-beta signaling pathway 💬 11 genes, 20 drugs (DrugBank) and 54 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
1476 | TGF-beta signaling pathway 💬 11 genes, 20 drugs (DrugBank) and 54 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
1477 | TGF-beta signaling pathway 💬 11 genes, 20 drugs (DrugBank) and 54 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1478 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D05092 D05092 💬 |
Muromonab | 060 [3] 60, 96, 97 💬 |
1479 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D06314 D06314 💬 |
Visilizumab | 096 [2] 96, 97 💬 |
1480 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
1481 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
1482 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
1483 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
1484 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
1485 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
JAK1 [4] JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
1486 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1487 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1488 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D05092 D05092 💬 |
Muromonab | 060 [3] 60, 96, 97 💬 |
1489 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D06314 D06314 💬 |
Visilizumab | 096 [2] 96, 97 💬 |
1490 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
1491 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IL23A [1] IL23A 💬 |
D10912 D10912 💬 |
Brazikumab | 096 [2] 96, 97 💬 |
1492 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IL23A [1] IL23A 💬 |
D10438 D10438 💬 |
Guselkumab | 037 [4] 37, 41, 96, 97 💬 |
1493 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IL23A [1] IL23A 💬 |
D11123 D11123 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 |
1494 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IL23A [1] IL23A 💬 |
D11052 D11052 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 |
1495 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IL23A [1] IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
1496 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
1497 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
1498 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
1499 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
JAK1 [4] JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
1500 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
1501 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1502 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1503 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1504 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
RARA [1] RARA 💬 |
D01418 D01418 💬 |
Tamibarotene | 026 [2] 26, 96 💬 |
1505 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
ADRB3 [1] ADRB3 💬 |
D00095 D00095 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
1506 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
ADRB3 [1] ADRB3 💬 |
D00996 D00996 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
1507 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
ADRB3 [1] ADRB3 💬 |
D02149 D02149 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
1508 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
CNR1 [1] CNR1 💬 |
D10915 D10915 💬 |
Cannabidiol | 002 [19] 2 , 6 , 8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 |
1509 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
CNR1 [1] CNR1 💬 |
D00306 D00306 💬 |
Dronabinol | 002 [7] 2 , 8 , 13, 46, 96, 271, 298 💬 |
1510 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
1511 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1512 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
1513 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
1514 | Thyroid cancer 💬 8 genes, 12 drugs (DrugBank) and 25 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
1515 | Thyroid cancer 💬 8 genes, 12 drugs (DrugBank) and 25 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
1516 | Thyroid hormone signaling pathway 💬 22 genes, 35 drugs (DrugBank) and 61 diseases |
ESR1 [1] ESR1 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
1517 | Thyroid hormone signaling pathway 💬 22 genes, 35 drugs (DrugBank) and 61 diseases |
HDAC1 [3] HDAC1, HDAC2, HDAC3 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
1518 | Thyroid hormone signaling pathway 💬 22 genes, 35 drugs (DrugBank) and 61 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
1519 | Thyroid hormone signaling pathway 💬 22 genes, 35 drugs (DrugBank) and 61 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1520 | Tight junction 💬 10 genes, 26 drugs (DrugBank) and 40 diseases |
CACNA1D [1] CACNA1D 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
1521 | Tight junction 💬 10 genes, 26 drugs (DrugBank) and 40 diseases |
CACNA1D [1] CACNA1D 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
1522 | TNF signaling pathway 💬 18 genes, 51 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
1523 | TNF signaling pathway 💬 18 genes, 51 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
1524 | TNF signaling pathway 💬 18 genes, 51 drugs (DrugBank) and 79 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
1525 | TNF signaling pathway 💬 18 genes, 51 drugs (DrugBank) and 79 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
1526 | TNF signaling pathway 💬 18 genes, 51 drugs (DrugBank) and 79 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
1527 | TNF signaling pathway 💬 18 genes, 51 drugs (DrugBank) and 79 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
1528 | TNF signaling pathway 💬 18 genes, 51 drugs (DrugBank) and 79 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1529 | Toll-like receptor signaling pathway 💬 34 genes, 39 drugs (DrugBank) and 64 diseases |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
1530 | Toll-like receptor signaling pathway 💬 34 genes, 39 drugs (DrugBank) and 64 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 |
1531 | Toll-like receptor signaling pathway 💬 34 genes, 39 drugs (DrugBank) and 64 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 |
1532 | Toll-like receptor signaling pathway 💬 34 genes, 39 drugs (DrugBank) and 64 diseases |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
1533 | Toll-like receptor signaling pathway 💬 34 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
1534 | Toll-like receptor signaling pathway 💬 34 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
1535 | Toll-like receptor signaling pathway 💬 34 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
1536 | Toll-like receptor signaling pathway 💬 34 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
1537 | Toll-like receptor signaling pathway 💬 34 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1538 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
1539 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
1540 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
1541 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
1542 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
JAK1 [3] JAK1, JAK2, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
1543 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
1544 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
1545 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
1546 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
1547 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1548 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
CD86 [1] CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
1549 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
ELANE [1] ELANE 💬 |
D03788 D03788 💬 |
Sivelestat | 013 [3] 13, 85, 96 💬 |
1550 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
HDAC1 [2] HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
1551 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
1552 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
1553 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
IL2RB [1] IL2RB 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
1554 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
ITGB7 [1] ITGB7 💬 |
D10540 D10540 💬 |
Abrilumab | 096 [2] 96, 97 💬 |
1555 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
ITGB7 [1] ITGB7 💬 |
D09901 D09901 💬 |
Etrolizumab | 096 [2] 96, 97 💬 |
1556 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
ITGB7 [1] ITGB7 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 |
1557 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
PPARG [1] PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
1558 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
1559 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
RARA [1] RARA 💬 |
D01418 D01418 💬 |
Tamibarotene | 026 [2] 26, 96 💬 |
1560 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
HLA-DMA [14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
1561 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
IL12A [3] IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
1562 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
IL23A [1] IL23A 💬 |
D10912 D10912 💬 |
Brazikumab | 096 [2] 96, 97 💬 |
1563 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
IL23A [1] IL23A 💬 |
D10438 D10438 💬 |
Guselkumab | 037 [4] 37, 41, 96, 97 💬 |
1564 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
IL23A [1] IL23A 💬 |
D11123 D11123 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 |
1565 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
IL23A [1] IL23A 💬 |
D11052 D11052 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 |
1566 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
1567 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
1568 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
JAK1 [2] JAK1, JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
1569 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1570 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1571 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
1572 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
1573 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
1574 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
1575 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1576 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
VDR [1] VDR 💬 |
D01518 D01518 💬 |
Alfacalcidol | 041 [6] 41, 46, 49, 50, 96, 235 💬 |
1577 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
VDR [1] VDR 💬 |
D00129 D00129 💬 |
Calcitriol | 037 [8] 37, 46, 49, 66, 96, 158, 235, 326 💬 |
1578 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
VDR [1] VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 [23] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 162, 202, 228, 271, 298, 299 💬 |
1579 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
VDR [1] VDR 💬 |
D00187 D00187 💬 |
Ergocalciferol | 046 [5] 46, 84, 96, 97, 299 💬 |
1580 | Type I diabetes mellitus 💬 31 genes, 23 drugs (DrugBank) and 69 diseases |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
1581 | Type I diabetes mellitus 💬 31 genes, 23 drugs (DrugBank) and 69 diseases |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
1582 | Type I diabetes mellitus 💬 31 genes, 23 drugs (DrugBank) and 69 diseases |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬 |
1583 | Type I diabetes mellitus 💬 31 genes, 23 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
1584 | Type I diabetes mellitus 💬 31 genes, 23 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
1585 | Type I diabetes mellitus 💬 31 genes, 23 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
1586 | Type I diabetes mellitus 💬 31 genes, 23 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
1587 | Type I diabetes mellitus 💬 31 genes, 23 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1588 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
1589 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
1590 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
1591 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
1592 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
1593 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
1594 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
1595 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
1596 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
1597 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
1598 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1599 | Ubiquinone and other terpenoid-quinone biosynthesis 💬 3 genes, 3 drugs (DrugBank) and 14 diseases |
NQO1 [2] NQO1, VKORC1 💬 |
D00564 D00564 💬 |
Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
1600 | Ubiquinone and other terpenoid-quinone biosynthesis 💬 3 genes, 3 drugs (DrugBank) and 14 diseases |
NQO1 [2] NQO1, VKORC1 💬 |
D01280 D01280 💬 |
Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
1601 | Ubiquinone and other terpenoid-quinone biosynthesis 💬 3 genes, 3 drugs (DrugBank) and 14 diseases |
NQO1 [2] NQO1, VKORC1 💬 |
D08682 D08682 💬 |
Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
1602 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
ADORA2A [1] ADORA2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1603 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
ADORA2A [1] ADORA2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
1604 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00095 D00095 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
1605 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00996 D00996 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
1606 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D02149 D02149 💬 |
Epinephrine | 046 [2] 46, 96 💬 |
1607 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
1608 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
1609 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
1610 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
1611 | VEGF signaling pathway 💬 20 genes, 48 drugs (DrugBank) and 84 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1612 | VEGF signaling pathway 💬 20 genes, 48 drugs (DrugBank) and 84 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1613 | VEGF signaling pathway 💬 20 genes, 48 drugs (DrugBank) and 84 diseases |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬 |
1614 | VEGF signaling pathway 💬 20 genes, 48 drugs (DrugBank) and 84 diseases |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
1615 | Viral carcinogenesis 💬 27 genes, 19 drugs (DrugBank) and 36 diseases |
HDAC1 [11] HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
1616 | Viral carcinogenesis 💬 27 genes, 19 drugs (DrugBank) and 36 diseases |
HLA-A [6] HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
1617 | Viral carcinogenesis 💬 27 genes, 19 drugs (DrugBank) and 36 diseases |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
1618 | Viral carcinogenesis 💬 27 genes, 19 drugs (DrugBank) and 36 diseases |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [7] 40, 41, 46, 49, 96, 97, 271 💬 |
1619 | Viral carcinogenesis 💬 27 genes, 19 drugs (DrugBank) and 36 diseases |
JAK1 [2] JAK1, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
1620 | Viral myocarditis 💬 29 genes, 18 drugs (DrugBank) and 46 diseases |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
1621 | Viral myocarditis 💬 29 genes, 18 drugs (DrugBank) and 46 diseases |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
1622 | Viral myocarditis 💬 29 genes, 18 drugs (DrugBank) and 46 diseases |
ITGAL [1] ITGAL 💬 |
D03959 D03959 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 |
1623 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 27 drugs (DrugBank) and 58 diseases |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [5] 2 , 49, 65, 96, 97 💬 |
1624 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 27 drugs (DrugBank) and 58 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
1625 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 27 drugs (DrugBank) and 58 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
1626 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 27 drugs (DrugBank) and 58 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
1627 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 27 drugs (DrugBank) and 58 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
1628 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 27 drugs (DrugBank) and 58 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
1629 | Wnt signaling pathway 💬 8 genes, 7 drugs (DrugBank) and 56 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1630 | Wnt signaling pathway 💬 8 genes, 7 drugs (DrugBank) and 56 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬 |
1631 | Yersinia infection 💬 20 genes, 32 drugs (DrugBank) and 66 diseases |
ITGA4 [1] ITGA4 💬 |
D10540 D10540 💬 |
Abrilumab | 096 [2] 96, 97 💬 |
1632 | Yersinia infection 💬 20 genes, 32 drugs (DrugBank) and 66 diseases |
ITGA4 [1] ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 [6] 13, 15, 25, 46, 63, 96 💬 |
1633 | Yersinia infection 💬 20 genes, 32 drugs (DrugBank) and 66 diseases |
ITGA4 [1] ITGA4 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 |
1634 | Yersinia infection 💬 20 genes, 32 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [16] 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
1635 | Yersinia infection 💬 20 genes, 32 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [6] 37, 46, 96, 97, 226, 271 💬 |
1636 | Yersinia infection 💬 20 genes, 32 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [6] 46, 56, 84, 96, 97, 271 💬 |
1637 | Yersinia infection 💬 20 genes, 32 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
1638 | Yersinia infection 💬 20 genes, 32 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |