DDrare: Database of Drug Development for Rare Diseases

124. 皮質下梗塞と白質脳症を伴う常染色体優性脳動脈症
［臨床試験数：11，薬物数：13（DrugBank：4），標的遺伝子数：3，標的パスウェイ数：11］

Searched query = "Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy", "CADASIL", "Autosomal dominant cerebral artery disease with subcortical infarct and leukoencephalopathy", "Autosomal dominant cerebral artery disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = 6R-BH4; ARICEPT 5*28 CPR 5 MG; Antiplatelets; Aricept; BH4; Dabigatran; Donepezil; Donepezil hydrochloride; E2020; Fremanezumab; HOV-12020 (Palm tocotrienols complex); Phenoptin; Sapropterin

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01361763 (ClinicalTrials.gov)	June 2011	16/5/2011	Safety Study of Dabigatran in CADASIL	Phase II, Randomized, Crossover, Single Blind, Safety Trial of DABIGATRAN Versus ASA for Preventing Ischaemic Brain Lesions in Patients Affected by CADASIL	CADASIL	Drug: Dabigatran;Drug: Antiplatelets	S. Andrea Hospital	NULL	Recruiting	18 Years	N/A	Both	50	Phase 2	Italy

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

NCT01361763
(ClinicalTrials.gov)

June 2011

16/5/2011

Safety Study of Dabigatran in CADASIL

Phase II, Randomized, Crossover, Single Blind, Safety Trial of DABIGATRAN Versus ASA for Preventing Ischaemic Brain Lesions in Patients Affected by CADASIL

CADASIL

Drug: Dabigatran;Drug: Antiplatelets

S. Andrea Hospital

NULL

Recruiting

18 Years

N/A

Both

Phase 2

Italy