DDrare: Database of Drug Development for Rare Diseases

149. 片側痙攣・片麻痺・てんかん症候群
［臨床試験数：22，薬物数：33（DrugBank：12），標的遺伝子数：13，標的パスウェイ数：17］

Searched query = "Hemiconvulsion hemiplegia epilepsy syndrome", "One side convulsions", "Hemiplegia", "Epilepsy syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = 4cc of lidocaïne®; 9060X; BOTOX; BOTULINUM TOXIN TYPE A; Baclofen; Balance; Botox; Botulinum toxin; Botulinum toxin A; Botulinum toxin type A; Brivaracetam; Diagnostic Test: Nociceptor flexor reflex; Diagnostic Test: gait analysis; Edonerpic; Gradient; HC-58; Lacosamide; MEOPA; Medicinal air; Melatonin; Other: Review of past medical history, clinical exam, and electroencephalogram, polysomnography and urine samples of melatonin and pupillometry.; Other: The patients' parents have to complete the VINELAND II adaptive behavior scales scoring, The Sleep Disturbance Scale for Children (SDSC) and Horne & Ostberg Circadian Typology Questionnaire; Oxybate; Padsevonil; Placebo; Procedure: upper limb muscle block; SPM927; Sodium Oxybate; Sodium oxybate; T-817MA; Time delay treatment of botulinum toxin; Triheptanoin; Ucb 34714

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-JapicCTI-194958	01/10/2019	18/09/2019	A pharmacokinetic, safety, and tolerability study of padsevonil in CYP2C19 genotyped healthy male Japanese study participants.	An Open-Label, Parallel Group, Single-Center Study to Investigate the Pharmacokinetic, Safety, and Tolerability Profiles of Padsevonil in CYP2C19 Genotyped Healthy Male Japanese Study Participants	Epilepsy and epilepsy syndrome	Intervention name : padsevonil INN of the intervention : padsevonil Dosage And administration of the intervention : Oral administration Control intervention name : - INN of the control intervention : - Dosage And administration of the control intervention : -	UCB Japan Co., Ltd.	NULL	complete	20	55	Male	39	Phase 1	Japan

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

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size

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JPRN-JapicCTI-194958

01/10/2019

18/09/2019

A pharmacokinetic, safety, and tolerability study of padsevonil in CYP2C19 genotyped healthy male Japanese study participants.

An Open-Label, Parallel Group, Single-Center Study to Investigate the Pharmacokinetic, Safety, and Tolerability Profiles of Padsevonil in CYP2C19 Genotyped Healthy Male Japanese Study Participants

Epilepsy and epilepsy syndrome

Intervention name : padsevonil
INN of the intervention : padsevonil
Dosage And administration of the intervention : Oral administration
Control intervention name : -
INN of the control intervention : -
Dosage And administration of the control intervention : -

UCB Japan Co., Ltd.

NULL

complete

Male

Phase 1

Japan