DDrare: Database of Drug Development for Rare Diseases

156. レット症候群
［臨床試験数：36，薬物数：49（DrugBank：19），標的遺伝子数：77，標的パスウェイ数：112］

Searched query = "Rett syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = ANA001XHCl (Syntagon) or VEXA-04 (Patheon); ANAVEX2-73; ANAVEX2-73 (blarcamesine); ANAVEX2-73 oral liquid; Acetate; Administration of a high dose of desipramine; Administration of a low dose of desipramine; Alpha-tocotrienol quinone; Blarcamesine; CANNABIDIOL; CBD; CBD - Oral Solution, is known as Epidyolex, and is the approved name; CBD Oral solution, is known as Epidyolex and is the approved name in the EU; Cannabidiol; Cannabidiol (CBD); Creatine; Creatine monohydrate; Desipramine; Dextromethorphan; Donepezil; Donepezil hydrochloride; EMD 128130; EPI-743; Epidyolex; Epidyolex and is the approved name in the EU; Fingolimod; Fingolimod (FTY720); GWP42003-P; Glatiramer; Glatiramer Acetate; Glatiramer Acetate (Copaxone®); Human insulin; Ketamine; Lactobacillus plantarum; Lovastatin; NNZ-2566; Probiotic-Lactobacillus plantarum PS128; Recombinant Human Insulin Growth Factor 1 (rhIGF-1); Rett-T; RhIGF-1; Risperidone; SARIZOTAN HYDROCHLORIDE; Sarizotan; Sarizotan hydrochloride; Tocotrienol; Topiramate; Tridecanoic Acid; Triheptanoin; Trofinetide

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00069550 (ClinicalTrials.gov)	September 2004	29/9/2003	Independent Studies of Dextromethorphan and of Donepezil Hydrochloride for Rett Syndrome	Pathogenesis of Rett Syndrome: Natural History and Treatment	Rett Syndrome	Drug: dextromethorphan;Drug: donepezil hydrochloride	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	NULL	Recruiting	1 Year	15 Years	Both	90	Phase 3	United States
2	NCT00004807 (ClinicalTrials.gov)	January 1995	24/2/2000	Study of the Pathogenesis of Rett Syndrome		Rett Syndrome	Drug: dextromethorphan;Drug: topiramate;Drug: Donepezil	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	Johns Hopkins University	Completed	N/A	45 Years	Both	120	N/A	NULL

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

NCT00069550
(ClinicalTrials.gov)

September 2004

29/9/2003

Independent Studies of Dextromethorphan and of Donepezil Hydrochloride for Rett Syndrome

Pathogenesis of Rett Syndrome: Natural History and Treatment

Rett Syndrome

Drug: dextromethorphan;Drug: donepezil hydrochloride

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NULL

Recruiting

1 Year

15 Years

Both

Phase 3

United States

NCT00004807
(ClinicalTrials.gov)

January 1995

24/2/2000

Study of the Pathogenesis of Rett Syndrome

Rett Syndrome

Drug: dextromethorphan;Drug: topiramate;Drug: Donepezil

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Johns Hopkins University

Completed

N/A

45 Years

Both

120

N/A

NULL