26. HTLV-1関連脊髄症
[臨床試験数:26,薬物数:46(DrugBank:27),標的遺伝子数:37,標的パスウェイ数:123

Searched query = "HTLV-1-associated myelopathy", "Tropical spastic paraparesis", "HTLV-1", "HTLV-I-associated myelopathy"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
3 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1JPRN-UMIN000024086
2016/09/1620/09/2016Phase IIb clinical trial of steroid therapy in patients with HAM(Non progressor) HTLV-1-Associated-Myelopathy Tropical Spastic Paraparesis (HAM/TSP)Drugs which possibly affect assessment in the study (e.g. methylprednisolone, prednisolone and other agents targeted to HAM) will be forbidden or limited until Week 48 and periodic evaluation and tests will be performed.St. Marianna University School of Medicine HospitalNULLRecruiting18years-oldNot applicableMale and Female5Phase 2bJapan
2JPRN-UMIN000024085
2016/09/1620/09/2016Phase IIb clinical trial of steroid therapy in patients with HAM(Slow progressor) HTLV-1-Associated-Myelopathy Tropical Spastic Paraparesis (HAM/TSP)Prednisolone is orally administered at a maximum dose of 0.5mg/kg/day and then tapered to a maintenance dose of 5mg/day.
Indistinguishable placebo is orally administered for 24 weeks, and then 5mg/day of prednisolone for the next 24 weeks.
St. Marianna University School of Medicine HospitalNULLRecruiting18years-oldNot applicableMale and Female40Phase 2;Phase 3Japan
3JPRN-UMIN000023798
2016/08/3131/08/2016Phase IIb clinical trial of steroid therapy in patients with HAM HTLV-1-Associated-Myelopathy Tropical Spastic Paraparesis (HAM/TSP)Following to administrate Methylprednisolone 1000mg/day intravenously slowly for consecutive three days, Prednisolone is administered orally for a maximum dose in 0.5mg/kg/day, then decreased gradually and terminated. There is a case to maintain the dose of Prednisolone by the degree of a progress of underlying disease.
Prednisolone is administered orally for a maximum dose in 0.5mg/kg/day, then decreased gradually and terminated. There is a case to maintain the dose of Prednisolone by the degree of a progress of underlying disease.
St. Marianna University School of Medicine HospitalNULLRecruiting18years-oldNot applicableMale and Female8Phase 2;Phase 3Japan