DDrare: Database of Drug Development for Rare Diseases

280. 巨大動静脈奇形（頚部顔面又は四肢病変）
［臨床試験数：22，薬物数：26（DrugBank：13），標的遺伝子数：11，標的パスウェイ数：147］

Searched query = "Huge arteriovenous malformation with cervicofacial or limb lesion", "Huge arteriovenous malformation", "Arteriovenous malformation"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = 68Ga-NEB; Bevacizumab; Bleomycin; Dexmedetomidine; Dexmedetomidine 1; Dexmedetomidine 2; Dexmedetomidine 3; Doxycycline; Ethanol; Heparin; Heparin Sodium; L04AA10; Lipiodol; Lipiodol® Ultra Fluid with surgical glues; Lovastatin; Mekinist; Minocycline; Other: normal saline; RAPAMUNE; Rapamune; SIROLIMUS; Sirolimus; Sirolimus 0,1% crème; Sirolimus 1mg/mL; Sufentanil; Thalidomide

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04297033 (ClinicalTrials.gov)	January 1, 2021	21/2/2020	Lovastatin for Treatment of Brain Arteriovenous Malformations	Lovastatin for Treatment of Brain Arteriovenous Malformations:a Double-blind, Placebo-controlled Randomized Trial	Cerebral Arteriovenous Malformation	Drug: Lovastatin;Drug: Placebo	Beijing Tiantan Hospital	NULL	Not yet recruiting	18 Years	N/A	All	1244	Phase 2	China

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

NCT04297033
(ClinicalTrials.gov)

January 1, 2021

21/2/2020

Lovastatin for Treatment of Brain Arteriovenous Malformations

Lovastatin for Treatment of Brain Arteriovenous Malformations:a Double-blind, Placebo-controlled Randomized Trial

Cerebral Arteriovenous Malformation

Drug: Lovastatin;Drug: Placebo

Beijing Tiantan Hospital

NULL

Not yet recruiting

18 Years

N/A

All

1244

Phase 2

China