DDrare: Database of Drug Development for Rare Diseases

40. 高安動脈炎
［臨床試験数：22，薬物数：46（DrugBank：20），標的遺伝子数：22，標的パスウェイ数：111］

Searched query = "Takayasu arteritis", "Aortitis syndrome", "Pulseless disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = AZA; Acetate; Adalimumab; Anti-thymocyte globulin; CYC; Clofarabine; Cyclophosphamide; Cyclosporine; DCB; Filgrastim; Glucocorticoids; INFLIXIMAB; Infliximab; Leflunomide; Leflunomide 10mg Tab; MMF; MTX; Methotrexate; Methotrexate Tablets; Methylprednisolone; Naltrexone; Naltrexone Hydrochloride; Placebo; Prednisolone; Prednisone; Prednisone Acetate; Prednisone acetate; Prednisone, cyclophosphamide; Procedure: Autologous Peripheral Blood Stem Cell Transplantation; Procedure: Computed Tomography; Procedure: Digital substraction angiography (DSA); Procedure: Drug coated balloon (DCB); Procedure: Positron Emission Tomography; Radiation: Fluorine F 18 Clofarabine; Remicade; Remicade (anti tumor necrosis factor inhibitor); RoActemra; RoActemra 20mg/ml; TOCILIZUMAB; Tocilizumab; Tocilizumab (MRA-SC); Tofacitinib; Tofacitinib tablet; Upadacitinib; Yellow Fever Vaccine; Yellow Fever vaccine (17D)

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03550781 (ClinicalTrials.gov)	June 1, 2018	5/5/2018	Anti-inflammatory Treatment for Inactive Takayasu Arteritis	Does Inactive Takayasu Arteritis(NIH Criteria) Need Anti-inflammatory Treatment?	Takayasu Arteritis;Anti-Inflammatory Agents	Drug: Prednisone , cyclophosphamide	Chinese Academy of Medical Sciences, Fuwai Hospital	NULL	Not yet recruiting	10 Years	40 Years	All	40	Phase 2;Phase 3	NULL
2	NCT03096275 (ClinicalTrials.gov)	March 16, 2017	13/3/2017	Comparison of Mycophenolate Mofetil and Cyclophosphamide for Active Takayasu's Arteritis	Comparison of the Efficacy of Mycophenolate Mofetil Combined With Methotrexate and Cyclophosphamide for the Treatment of Takayasu's Arteritis	Takayasu Arteritis	Drug: MMF;Drug: CYC;Drug: Glucocorticoids;Drug: MTX;Drug: AZA	Chinese SLE Treatment And Research Group	Peking Union Medical College Hospital	Recruiting	18 Years	N/A	All	150	Phase 3	China
3	NCT00006055 (ClinicalTrials.gov)	March 2000	5/7/2000	Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases		Purpura, Schoenlein-Henoch;Graft Versus Host Disease;Anemia, Hemolytic, Autoimmune;Rheumatoid Arthritis;Churg-Strauss Syndrome;Hypersensitivity Vasculitis;Wegener's Granulomatosis;Systemic Lupus Erythematosus;Giant Cell Arteritis;Pure Red Cell Aplasia;Juvenile Rheumatoid Arthritis;Polyarteritis Nodosa;Autoimmune Thrombocytopenic Purpura;Takayasu Arteritis	Drug: anti-thymocyte globulin;Drug: cyclophosphamide;Drug: cyclosporine;Drug: filgrastim;Drug: methylprednisolone;Drug: prednisone;Procedure: Autologous Peripheral Blood Stem Cell Transplantation	Fairview University Medical Center	NULL	Active, not recruiting	1 Year	55 Years	Both	10	N/A	United States

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

NCT03550781
(ClinicalTrials.gov)

June 1, 2018

5/5/2018

Anti-inflammatory Treatment for Inactive Takayasu Arteritis

Does Inactive Takayasu Arteritis(NIH Criteria) Need Anti-inflammatory Treatment?

Takayasu Arteritis;Anti-Inflammatory Agents

Drug: Prednisone , cyclophosphamide

Chinese Academy of Medical Sciences, Fuwai Hospital

NULL

Not yet recruiting

10 Years

40 Years

All

Phase 2;Phase 3

NULL

NCT03096275
(ClinicalTrials.gov)

March 16, 2017

13/3/2017

Comparison of Mycophenolate Mofetil and Cyclophosphamide for Active Takayasu's Arteritis

Comparison of the Efficacy of Mycophenolate Mofetil Combined With Methotrexate and Cyclophosphamide for the Treatment of Takayasu's Arteritis

Takayasu Arteritis

Drug: MMF;Drug: CYC;Drug: Glucocorticoids;Drug: MTX;Drug: AZA

Chinese SLE Treatment And Research Group

Peking Union Medical College Hospital

Recruiting

18 Years

N/A

All

150

Phase 3

China

NCT00006055
(ClinicalTrials.gov)

March 2000

5/7/2000

Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases

Purpura, Schoenlein-Henoch;Graft Versus Host Disease;Anemia, Hemolytic, Autoimmune;Rheumatoid Arthritis;Churg-Strauss Syndrome;Hypersensitivity Vasculitis;Wegener's Granulomatosis;Systemic Lupus Erythematosus;Giant Cell Arteritis;Pure Red Cell Aplasia;Juvenile Rheumatoid Arthritis;Polyarteritis Nodosa;Autoimmune Thrombocytopenic Purpura;Takayasu Arteritis

Drug: anti-thymocyte globulin;Drug: cyclophosphamide;Drug: cyclosporine;Drug: filgrastim;Drug: methylprednisolone;Drug: prednisone;Procedure: Autologous Peripheral Blood Stem Cell Transplantation

Fairview University Medical Center

NULL

Active, not recruiting

1 Year

55 Years

Both

N/A

United States