46. 悪性関節リウマチ
[臨床試験数:4,183,薬物数:2,538(DrugBank:401),標的遺伝子数:183,標的パスウェイ数:219]
Searched query = "Malignant rheumatoid arthritis", "Rheumatoid arthritis", "Rheumatoid arthritis with vasculitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | EUCTR2009-014824-40-CZ (EUCTR) | 03/11/2009 | 03/09/2009 | An open label follow on study to evaluate the long-term safety, tolerability and efficacy of ART621 following fortnightly administration for 48 weeks in patients with rheumatoid arthritis concomitantly taking methotrexate. | An open label follow on study to evaluate the long-term safety, tolerability and efficacy of ART621 following fortnightly administration for 48 weeks in patients with rheumatoid arthritis concomitantly taking methotrexate. | Rheumatoid arthritis | Product Code: ART621 | Arana Therapeutics Ltd | NULL | Not Recruiting | Female: yes Male: yes | 200 | Czech Republic | |||
2 | NCT00928317 (ClinicalTrials.gov) | April 2009 | 24/6/2009 | Dose Ranging Study of ART621 in Subjects Diagnosed With Rheumatoid Arthritis Taking Methotrexate | Multi-Centre Randomised Double-Blind Pbo-Controlled Dose-Ranging Study to Evaluate the Safety, Tolerability, Efficacy, PK and Immunogenicity of Multiple Doses of ART621 for 3 Months in Patients With Rheumatoid Arthritis Taking Methotrexate | Rheumatoid Arthritis | Drug: ART621;Drug: Placebo | Arana Therapeutics Ltd | NULL | Terminated | 18 Years | 80 Years | Both | 13 | Phase 2 | United States;Argentina;Australia;Czech Republic;India;Malaysia;New Zealand;Poland |
3 | EUCTR2008-006930-92-CZ (EUCTR) | 31/03/2009 | 06/01/2009 | A multi-centre randomised, double-blind, placebo-controlled, dose-ranging study to evaluate the safety, tolerability, efficacy, pharmacokinetics and immunogenicity of ART621 following multiple dose administration for 3 months in patients with rheumatoid arthritis concomitantly taking methotrexate | A multi-centre randomised, double-blind, placebo-controlled, dose-ranging study to evaluate the safety, tolerability, efficacy, pharmacokinetics and immunogenicity of ART621 following multiple dose administration for 3 months in patients with rheumatoid arthritis concomitantly taking methotrexate | Rheumatoid arthritis MedDRA version: 9.1;Level: LLT;Classification code 10039073;Term: Rheumatoid arthritis | Product Code: ART621 | Arana Therapeutics Ltd | NULL | Not Recruiting | Female: yes Male: yes | 200 | Czech Republic | |||
4 | NCT00854685 (ClinicalTrials.gov) | February 2009 | 1/3/2009 | Dose Optimisation Study of ART621 in Subjects Diagnosed With Rheumatoid Arthritis Taking Methotrexate | A Factorial-design, Randomised, Double-blind, Placebo-controlled, Dose Optimisation Study to Investigate the Safety, Efficacy, Immunogenicity and Pharmacokinetics of ART621 Following Multiple Dose Administration in Subjects Diagnosed With Rheumatoid Arthritis Concomitantly Taking Methotrexate | Rheumatoid Arthritis | Drug: ART621;Drug: Placebo | Arana Therapeutics Ltd | Trident Clinical Research Pty Ltd | Completed | 18 Years | 80 Years | Both | 27 | Phase 2 | Sri Lanka |