DDrare: Database of Drug Development for Rare Diseases

Searched query = "Tuberous sclerosis", "Tuberous sclerosis complex"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	ChiCTR-DDD-17010586	2016-01-01	2017-02-08	Prenatal diagnosis of tuberous sclerosis by fetal echocardiography combined with high throughput gene sequencing	Prenatal diagnosis of TSC using high-throughput gene sequencing combined with fetal echocardiography	Tuberous sclerosis complex	Gold Standard:A Clinical diagnostic criteria of tuberous sclerosis (TSC) for the postnatal population 1. Definite diagnosis: 2 major features or 1 major feature and 2 minor teatures 2. Possible diagnosis: 1 major feature or 2 minor features [major features: (1) Facial angiofibro or forehead plaque, (2) 'Nontraumatic' periungual&#;Index test:1. Prenatal diagnosis of TSC high-risk fetus by the traditional method (amniocentesis) using the gold standard; 2. Prenatal diagnosis of TSC high-risk fetus by maternal peripheral blood gene detection.;	An Zhen Hospital affiliated to Capital Medical University, Beijing;Beijing Key Laboratory of Fetal Heart Diseases and Maternal-Fetal Medicine	NULL	Recruiting			Female	Target condition:30;Difficult condition:5		China

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

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sponsor

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sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

ChiCTR-DDD-17010586

2016-01-01

2017-02-08

Prenatal diagnosis of tuberous sclerosis by fetal echocardiography combined with high throughput gene sequencing

Prenatal diagnosis of TSC using high-throughput gene sequencing combined with fetal echocardiography

Tuberous sclerosis complex

Gold Standard:A Clinical diagnostic criteria of tuberous sclerosis (TSC) for the postnatal population
1. Definite diagnosis: 2 major features or 1 major feature and 2 minor teatures
2. Possible diagnosis: 1 major feature or 2 minor features
[major features: (1) Facial angiofibro or forehead plaque, (2) 'Nontraumatic' periungual&#;Index test:1. Prenatal diagnosis of TSC high-risk fetus by the traditional method (amniocentesis) using the gold standard;
2. Prenatal diagnosis of TSC high-risk fetus by maternal peripheral blood gene detection.;

An Zhen Hospital affiliated to Capital Medical University, Beijing;Beijing Key Laboratory of Fetal Heart Diseases and Maternal-Fetal Medicine

NULL

Recruiting

Female

Target condition:30;Difficult condition:5

China