211. Hypoplastic left heart syndrome
20 clinical trials,   28 drugs   (DrugBank: 9 drugs),   5 drug target genes,   13 drug target pathways
Searched query = "Hypoplastic left heart syndrome", "HLHS"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | NCT03779711 (ClinicalTrials.gov) | December 12, 2018 | 4/12/2018 | Intramyocardial Injection of Autologous Umbilical Cord Blood Derived Mononuclear Cells During Surgical Repair of Hypoplastic Left Heart Syndrome | Phase IIb Study of Intramyocardial Injection of Autologous Umbilical Cord Blood Derived Mononuclear Cells During Stage II Surgical Repair of Right Ventricular Dependent Variants of Hypoplastic Left Heart Syndrome (AutoCell-S2) | Hypoplastic Left Heart Syndrome | Biological: Autologous (self) mononuclear cells derived from umbilical cord blood;Procedure: Stage II Surgical repair | Timothy J Nelson, MD, PhD | University of Oklahoma;Children's Hospital of Philadelphia;Children's Hospital Los Angeles;Children's Hospital Colorado;Children's Hospitals and Clinics of Minnesota;Ochsner Health System;Children's of Alabama | Recruiting | N/A | 12 Months | All | 100 | Phase 2 | United States |
2 | NCT01883076 (ClinicalTrials.gov) | May 15, 2013 | 11/6/2013 | Safety Study of Autologous Umbilical Cord Blood Cells for Treatment of Hypoplastic Left Heart Syndrome | Phase I Safety Study of Autologous Umbilical Cord Blood Derived Mononuclear Cells During Surgical Stage II Palliation of Hypoplastic Left Heart Syndrome | Hypoplastic Left Heart Syndrome | Biological: autologous cell-based delivery | Timothy J Nelson, MD, PhD | University of Oklahoma;Children's Hospital of Philadelphia;Children's Hospitals and Clinics of Minnesota;Children's Hospital Los Angeles;Children's Hospital Colorado;Mayo Clinic | Active, not recruiting | N/A | 18 Months | All | 30 | Phase 1 | United States |
3 | NCT01445041 (ClinicalTrials.gov) | September 1, 2011 | 15/9/2011 | Safety and Feasibility Study of Umbilical Cord Blood Cells for Infants With Hypoplastic Left Heart Syndrome | Autologous Cord Blood Cells for Patients With HLHS: Phase I Study of Feasibility and Safety | Hypoplastic Left Heart Syndrome | Biological: Autologous Umbilical Cord Blood | Michael Cotten | NULL | Terminated | N/A | 2 Days | All | 7 | Phase 1 | United States |