215. Tetralogy of Fallot
19 clinical trials,   35 drugs   (DrugBank: 16 drugs),   16 drug target genes,   47 drug target pathways
Searched query = "Tetralogy of Fallot", "Fallot tetralogy"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | ChiCTR2000033234 | 2020-06-05 | 2020-05-25 | Comprehensive study for surgical effect and prognosis of Tetralogy of Fallot | A single-center ambispective cohort study for surgical effect and prognostic factors of Tetralogy of Fallot after surgical repair | Tetralogy of Fallot | TOF AS:annlus-sparing repair;TOF TAPE:transannular patch enlargement; | Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College | NULL | Pending | Both | TOF AS:247;TOF TAPE:247; | N/A | China | ||
2 | NCT03835494 (ClinicalTrials.gov) | November 1, 2018 | 8/1/2019 | Analysis of RV-Dysfunction in Fallot Patients | Tissue Doppler Imaging - A Promising Technique To Assess Myocardial Function In Adult Fallot Patients | Tetralogy of Fallot | Other: Transthoracic echocardiography at rest, during PLR, HG and CPX (including blood gas analysis in both groups). Additionally Fallot patients will undergo routine blood testings. | Klinik für Kardiologie, Pneumologie und Angiologie | NULL | Completed | 18 Years | 80 Years | All | 60 | N/A | Germany |
3 | NCT03732742 (ClinicalTrials.gov) | November 2018 | 22/10/2018 | Comparison of Mid-term Results of Total Correction of TOF Between Preservation of PV and Trans-annular Patch. | Comparison of Mid-term Results of Total Correction of Tetralogy of Fallot Between Preservation of Pulmonary Valve and Trans-annular Patching | Tetrology of Fallot | Procedure: TOF repair with trans-annular patch VS preservation of PV | Assiut University | NULL | Unknown status | N/A | N/A | All | 50 | N/A | NULL |
4 | EUCTR2013-002091-41-NL (EUCTR) | 09/10/2014 | 05/11/2013 | Research into the effect of the drug losartan in adult patients with a reduced function of the right cardiac chamber and a cardiac birth defect | Right vEntricular Dysfunction in tEtralogy of Fallot: INhibition of the rEnin-angiotensin-aldosterone system - Redefine trial | To study the effect of losartan in adult patients with Tetralogy of Fallot and right ventricular dysfunction, defined as right ventricular ejection fraction <50%. Without severe valvular lesions.;Therapeutic area: Diseases [C] - Cardiovascular Diseases [C14] | Trade Name: Losartan Product Name: Losartan INN or Proposed INN: Losartan Potassium Other descriptive name: LOSARTAN POTASSIUM | Academisch medisch centrum | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | Netherlands | ||||
5 | EUCTR2007-003461-41-DE (EUCTR) | 13/11/2007 | 10/09/2007 | Cardiac imaging under dobutamine stress for early assessment of right ventricular function in patients with tetralogy of Fallot and pulmonary regurgitation - Fallot-stress | Cardiac imaging under dobutamine stress for early assessment of right ventricular function in patients with tetralogy of Fallot and pulmonary regurgitation - Fallot-stress | Fallot tetralogy late after repair with marked pulmonary valve incompetence | INN or Proposed INN: Dobutamine | Deutsche Herzzentrum Berlin, Kompetenznetz Angeborene Herzfehler | NULL | Not Recruiting | Female: yes Male: yes | 80 | Germany | |||
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
6 | NCT00564993 (ClinicalTrials.gov) | November 2007 | 28/11/2007 | Cardiac Function Under Stress for Early Detection of the Right Ventricular Insufficiency After Repair of Tetralogy of Fallot | Cardiac Imaging Under Exercise Stress Test for Early Assessment of Right Ventricular Function in Patients With Tetralogy of Fallot and Pulmonary Regurgitation | Tetralogy of Fallot | Drug: Dobutamin | Competence Network for Congenital Heart Defects | German Federal Ministry of Education and Research | Terminated | 14 Years | N/A | Both | 53 | Phase 3 | Germany |