227. Osler disease
49 clinical trials,   69 drugs   (DrugBank: 21 drugs),   23 drug target genes,   132 drug target pathways
Searched query = "Osler disease", "Hereditary hemorrhagic telangiectasia", "Osler-Weber-Rendu disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NCT01408030 (ClinicalTrials.gov) | August 2011 | 1/8/2011 | North American Study of Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT) | North American Study of Epistaxis in HHT (NOSE) | Telangiectasia, Hereditary Hemorrhagic;Epistaxis | Drug: Sterile saline;Drug: Bevacizumab;Drug: Estriol;Drug: Tranexamic Acid | James Gossage | HHT Foundation International | Completed | 18 Years | N/A | All | 123 | Phase 2 | United States |
2 | NCT01031992 (ClinicalTrials.gov) | March 2002 | 11/12/2009 | Tranexamic Acid and Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT) | Efficacy of Tranexamic Acid Taken Orally in Patients With Hereditary Hemorrhagic Telangiectasia | Hereditary Hemorrhagic Telangiectasia | Drug: Tranexamic acid first, than placebo;Drug: First placebo, than Tranexamic acid. | University Hospital, Saarland | Pharmacia GmbH, Erlangen, Germany;Baxter Healthcare Corporation | Completed | 18 Years | N/A | Both | 23 | Phase 3 | Germany |