240. Phenylketonuria
125 clinical trials,   95 drugs   (DrugBank: 11 drugs),   1 drug target gene,   5 drug target pathways
Searched query = "Phenylketonuria", "PKU", "Phenylalanine hydroxylase deficiency", "PAH deficiency", "Tetrahydrobiopterin deficiency", "BH4 deficiency", "BH4 reactive hyper pheemia"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | NCT04534842 (ClinicalTrials.gov) | August 25, 2020 | 24/8/2020 | Efficacy and Safety of SYNB1618 in Adult Patients With Phenylketonuria | An Open-label Study of the Efficacy and Safety of SYNB1618 in Patients With Phenylketonuria (SynPheny-1) | Phenylketonuria | Drug: SYNB1618 | Synlogic | NULL | Recruiting | 18 Years | N/A | All | 12 | Phase 2 | United States |
2 | NCT03516487 (ClinicalTrials.gov) | April 17, 2018 | 11/4/2018 | Safety and Tolerability of SYNB1618 in Healthy Adult Volunteers and Adult Subjects With Phenylketonuria | A Phase 1/2a, First-in-human, Oral Single and Multiple Dose-escalation, Randomized, Double-blinded, Placebo-controlled Study of SYNB1618 in Healthy Adult Volunteers and Adult Subjects With Phenylketonuria to Evaluate Safety, Tolerability, Kinetics, and Pharmacodynamics | Phenylketonuria;Healthy | Drug: SYNB1618;Drug: Placebo | Synlogic | NULL | Completed | 18 Years | 64 Years | All | 70 | Phase 1;Phase 2 | United States |