DDrare: Database of Drug Development for Rare Diseases

Searched query = "Hereditary pancreatitis", "Chronic pancreatitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = 98% dehydrated alcohol; A04AD10; ACETYLCYSTEINE; ANTOX; ANTOX (vers) 1.2; ANTOX (vers.)1.2; ASCORBIC ACID; Acetate; Acetyl-L-carnitine; Acetyl-L-carnitine 1000mg 2X per day for 3 months; Acetylcysteine; Alanine; Alcohol; Alpha 1-Antitrypsin; Alpha 1-antitrypsin; Amino acids; Amlodipine; Amlodipine (drug); Analgesics; Antioxidant plus Pregabalin; Antioxidants; Antox version 1.2; Ascorbic acid; Autologous mesenchymal stromal cell; Behavioral: smoking and alcohol assumption; Benzoyl-L-tyrosyl-[1-13C]alanine (Bz-Tyr-Ala); Bupivacaine; Bupivicaine alone; CREON; Calcium; Calcium, Dietary; Carbon; Carbon monoxide; Carnitine; Cholecalciferol; Creon; Creon 10000; Creon 25000; Creon36™; DRONABINOL; Device: Mayo Interactive Breath Hold Monitor; Diagnostic Test: Hemoglobin A1c; Diagnostic Test: Mixed Meal Tolerance Test; Diagnostic Test: Other exploratory blood biomarkers; Diagnostic Test: genetic sequencing; Diazepam; Dronabinol; ERCP with Bupivacaine infusion; EUR-1008 (APT-1008) High Dose; EUR-1008 (APT-1008) Low Dose; EUR-1066-A; EUR-1066-B; EUS procedure with drug injection; Ensure Surgical; Esomeprazole; Etanercept; FLUIMUCIL*20CPR EFF 600MG; Fluimucil; Gabapentin; Gabapentin prescriptions; Gold; Helopanflat Mono®; Hemoglobin; Human Secretin; Human secretin; Hydroxychloroquine; Indomethacin; Intra Plexus Triamcinolone and Bupivicaine Injection; Kreon 25000; L-Carnitine; LANREOTIDE ACETATE; LIPASE; Lannacher; Lanreotide; Liprotamase; Lyrica; Lyrica®; MAGNESIUM ASPARTATE HYDROCHLORIDE; METHIONINE; MONITOR; MS1819; MS1819-SD; Magnesiocard 2.5mmol; Magnesium; Magnesium aspartate; Methionine; Mezym F; Midazolam; Multienzymes (lipase, protease etc.); NI-03; Namisol; Nexium (esomeprazole magnesium); OXYCODONE; OXYCODONE HYDROCHLORIDE; Omeprazole; Other: Carbon monoxide-bubbled mediums; Other: EUS procedure; Other: Laboratory Biomarker Analysis; Other: Low-intensity exercise therapy; Other: No enzyme therapy; Other: Nutrition counseling; Other: Quality-of-Life Assessment; Other: Questionnaire Administration; Oxycodone; Oxycodone Depot ”Sandoz”, depot tablets; Oxycodonhydrochlorid ”Lannacher”, depot tablets; Oxynorm; PFD; PL 00512/0150; Pancreatic enzymes; Pancreatin; Pancrelipase; Pancrelipase Delayed Release Capsule; Pancrelipase delayed release capsule; Pancrelipase/Pancreas Powder; Panzytrat; Panzytrat 25.000; Panzytrat 25.000 FIP-E units of Lipase; Pentoxifylline; Perflubutane; Pioglitazone; Pregabalin; Procedure: Celiac Block with triamcinolone and bupivicaine; Procedure: No Celiac Block; Procedure: endoscopic drainage of the main pancreatic duct; Procedure: extracorporeal shock wave lithotripsy; Prolastin; Prolastin-C; Proton pump inhibitor (PPI); REGN475/SAR164877; RG1068 (Synthetic Human Secretin); RVG 13760; Radiation: UV-filtered light.; Radiation: UVB; Recombinant Microbial Lipase SLV339; Recombinant microbial lipase; Reparixin; S-Ketamin; S-ketamin; SA; SA-001; SELENIUM; SLV339; Secretin; Selenium; Simvastatin; Somatuline; Somatuline Autogel 90 mg; Soy bread; Synthetic human secretin; TOCOPHEROL; Tanezumab; Tetrahydro-6,6,9-tri methyl-3-penthyl-6 H-dibenzo[ b,d ]pyran-1-ol; Tetrahydrocannabinol; Thalidomide; Tocopherol; Triamcinolone; Tyr; VIOKASE 16; Viokase 16; Viokase 16 (pancrelipase) + Nexium; Viokase® 16; Vitamin D; Vitamin D 100ug; Vitamin D 10ug; Yarrowia lipolytica lipase; ZENTASE; Zenpep

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02965898 (ClinicalTrials.gov)	September 2016	23/9/2016	The Effect of Vitamin D Substitution on the Development of Chronic Pancreatitis	The Effect of Vitamin D Substitution on Pancreatic Parenchyma and Development of Fibrosis After First Acute Alcoholic Pancreatitis: A Randomized Prospective Trial	Chronic Pancreatitis	Dietary Supplement: Vitamin D 100ug;Dietary Supplement: Vitamin D 10ug	Tampere University Hospital	Orion Corporation, Orion Pharma	Recruiting	18 Years	101 Years	All	260	N/A	Finland
2	NCT04574297 (ClinicalTrials.gov)	January 1, 2011	27/9/2020	An Observational Study on the Natural Course of Chronic Pancreatitis	The Impact of Genetic and Environmental Factors on the Progression of Chronic Pancreatitis:An Observational Study	Chronic Pancreatitis;Genetic Mutation;Smoking, Tobacco;Drinking, Alcohol	Behavioral: smoking and alcohol assumption;Diagnostic Test: genetic sequencing	Changhai Hospital	NULL	Active, not recruiting	N/A	N/A	All	965		NULL
3	NCT00782795 (ClinicalTrials.gov)	November 2008	29/10/2008	Chronic Pancreatitis. Effect of Pioglitazone on Endocrine Function, Exocrine Function & Structure, Pain & Life Quality	Phase II Study of Chronic Pancreatitis and the Effect of Pioglitazone on Endocrine Function, Exocrine Function & Structure, Pain & Life Quality	Chronic Pancreatitis;Insulin Resistance;Normal or Mildly Abnormal Stool Fat Levels	Drug: Pioglitazone;Drug: Placebo	University of Michigan	National Institute on Alcohol Abuse and Alcoholism (NIAAA);Takeda Pharmaceuticals North America, Inc.	Completed	18 Years	75 Years	All	64	Phase 2	United States
4	NCT00583271 (ClinicalTrials.gov)	June 2002	20/12/2007	A Prospective Study of EUS Guided Celiac Block	A Prospective Study of Endoscopic Ultrasound-guided Celiac (CB) Effectiveness	Chronic Pancreatitis;Pancreatic Cancer	Drug: triamcinolone;Drug: 98% dehydrated alcohol	Indiana University	NULL	Completed	18 Years	N/A	Both	127	N/A	United States

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

NCT02965898
(ClinicalTrials.gov)

September 2016

23/9/2016

The Effect of Vitamin D Substitution on the Development of Chronic Pancreatitis

The Effect of Vitamin D Substitution on Pancreatic Parenchyma and Development of Fibrosis After First Acute Alcoholic Pancreatitis: A Randomized Prospective Trial

Chronic Pancreatitis

Dietary Supplement: Vitamin D 100ug;Dietary Supplement: Vitamin D 10ug

Tampere University Hospital

Orion Corporation, Orion Pharma

Recruiting

18 Years

101 Years

All

260

N/A

Finland

NCT04574297
(ClinicalTrials.gov)

January 1, 2011

27/9/2020

An Observational Study on the Natural Course of Chronic Pancreatitis

The Impact of Genetic and Environmental Factors on the Progression of Chronic Pancreatitis:An Observational Study

Chronic Pancreatitis;Genetic Mutation;Smoking, Tobacco;Drinking, Alcohol

Behavioral: smoking and alcohol assumption;Diagnostic Test: genetic sequencing

Changhai Hospital

NULL

Active, not recruiting

N/A

All

965

NULL

NCT00782795
(ClinicalTrials.gov)

November 2008

29/10/2008

Chronic Pancreatitis. Effect of Pioglitazone on Endocrine Function, Exocrine Function & Structure, Pain & Life Quality

Phase II Study of Chronic Pancreatitis and the Effect of Pioglitazone on Endocrine Function, Exocrine Function & Structure, Pain & Life Quality

Chronic Pancreatitis;Insulin Resistance;Normal or Mildly Abnormal Stool Fat Levels

Drug: Pioglitazone;Drug: Placebo

University of Michigan

National Institute on Alcohol Abuse and Alcoholism (NIAAA);Takeda Pharmaceuticals North America, Inc.

Completed

18 Years

75 Years

All

Phase 2

United States

NCT00583271
(ClinicalTrials.gov)

June 2002

20/12/2007

A Prospective Study of EUS Guided Celiac Block

A Prospective Study of Endoscopic Ultrasound-guided Celiac (CB) Effectiveness

Chronic Pancreatitis;Pancreatic Cancer

Drug: triamcinolone;Drug: 98% dehydrated alcohol

Indiana University

NULL

Completed

18 Years

N/A

Both

127

N/A

United States