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299. Cystic fibrosis
1,592 clinical trials,   1,539 drugs   (DrugBank: 255 drugs),   81 drug target genes,   162 drug target pathways

Searched query = "Cystic fibrosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
7 trials found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1EUCTR2019-002840-26-GB
(EUCTR)		22/12/202003/09/2020Study of safety, tolerability, pharmacokinetics and pharmacodynamics of QBW251 in subjects with bronchiectasisA randomized, subject- and investigator-blinded, placebo-controlled, parallel group study to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of QBW251 in patients with bronchiectasis Bronchiectasis
MedDRA version: 23.0;Level: LLT;Classification code 10083611;Term: Non-cystic fibrosis bronchiectasis;System Organ Class: 100000004855;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]		Product Code: QBW251
INN or Proposed INN: Icenticaftor
Other descriptive name: CFTR potentiator		Novartis Pharma AGNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes		72Phase 2Spain;Germany;China;United Kingdom
2EUCTR2011-005085-37-FR
(EUCTR)		21/05/201517/06/2015Safety, tolerability, pharmacokinetics and preliminary pharmacodynamics of QBW251 in healthy subjects and cystic fibrosis patients.A randomized, double blind placebo-controlled study to assess the safety, tolerability, pharmacokinetics, and preliminary pharmacodynamics of single and multiple ascending doses of QBW251 in healthy subjects and multiple doses in cystic fibrosis patients cystic fibrosis
MedDRA version: 18.0;Level: PT;Classification code 10011762;Term: Cystic fibrosis;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]		Product Code: QBW251
INN or Proposed INN: Not assigned
Product Code: QBW251
INN or Proposed INN: Not assigned		Novartis Pharma Services AGNULLNot RecruitingFemale: yes
Male: yes		140United States;France;Belgium;Ireland;Germany;United Kingdom
3EUCTR2011-005085-37-BE
(EUCTR)		06/05/201526/03/2015Safety, tolerability, pharmacokinetics and preliminary pharmacodynamics of QBW251 in healthy subjects and cystic fibrosis patients.A randomized, double blind placebo-controlled study to assess the safety,tolerability, pharmacokinetics, and preliminary pharmacodynamics of single and multiple ascending doses of QBW251 in healthy subjects and multiple doses in cystic fibrosis patients cystic fibrosis
MedDRA version: 17.1;Level: PT;Classification code 10011762;Term: Cystic fibrosis;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]		Product Code: QBW251
INN or Proposed INN: Not assigned
Product Code: QBW251
INN or Proposed INN: Not assigned
Product Code: QBW251
INN or Proposed INN: Not assigned		Novartis Pharma Services AGNULLNot RecruitingFemale: yes
Male: yes		156France;United States;Belgium;Ireland;United Kingdom
4EUCTR2011-005085-37-IE
(EUCTR)		05/06/201410/04/2014Safety, tolerability, pharmacokinetics and preliminary pharmacodynamics of QBW251 in healthy subjects and cystic fibrosis patients.A randomized, double blind placebo-controlled study to assess the safety,tolerability, pharmacokinetics, and preliminary pharmacodynamics of single and multiple ascending doses of QBW251 in healthy subjects and multiple doses in cystic fibrosis patients cystic fibrosis
MedDRA version: 16.1;Level: PT;Classification code 10011762;Term: Cystic fibrosis;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]		Product Code: QBW251
INN or Proposed INN: Not assigned
Product Code: QBW251
INN or Proposed INN: Not assigned
Product Code: QBW251
INN or Proposed INN: Not assigned		Novartis Pharma Services AGNULLNot RecruitingFemale: yes
Male: yes		156France;United States;Belgium;Ireland;United Kingdom
5EUCTR2011-005085-37-DE
(EUCTR)		09/05/201431/03/2014Safety, tolerability, pharmacokinetics and preliminary pharmacodynamics of QBW251 in healthy subjects and cystic fibrosis patients.A randomized, double blind placebo-controlled study to assess the safety,tolerability, pharmacokinetics, and preliminary pharmacodynamics of single and multiple ascending doses of QBW251 in healthy subjects and multiple doses in cystic fibrosis patients cystic fibrosis
MedDRA version: 18.1;Level: PT;Classification code 10011762;Term: Cystic fibrosis;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]		Product Code: QBW251
INN or Proposed INN: Not assigned
Product Code: QBW251
INN or Proposed INN: Not assigned
Product Code: QBW251
INN or Proposed INN: Not assigned		Novartis Pharma Services AGNULLNot RecruitingFemale: yes
Male: yes		156Phase 1;Phase 2France;United States;Belgium;Ireland;Germany;United Kingdom
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
6NCT02190604
(ClinicalTrials.gov)		July 31, 201211/7/2014Safety, Tolerability, Pharmacokinetics, and Preliminary Pharmacodynamics of QBW251 in Healthy Subjects and Cystic Fibrosis PatientsA Randomized, Double Blind Placebo-controlled Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Pharmacodynamics of Single and Multiple Ascending Doses of QBW251 in Healthy Subjects and Multiple Doses in Cystic Fibrosis PatientsCystic FibrosisDrug: Placebo;Drug: QBW251Novartis PharmaceuticalsNULLTerminated18 Years65 YearsAll153Phase 1;Phase 2United States;Belgium;France;Germany;Ireland;Romania;United Kingdom;Netherlands
7EUCTR2011-005085-37-GB
(EUCTR)		20/07/201224/05/2012Safety, tolerability, pharmacokinetics and preliminary pharmacodynamics of QBW251 in healthy subjects and cystic fibrosis patients.A randomized, double blind placebo-controlled study to assess the safety, tolerability, pharmacokinetics and preliminary pharmacodynamics of single and multiple ascending doses of QBW251 in healthy subjects and multiple doses in cystic fibrosis patients. cystic fibrosis
MedDRA version: 17.0;Level: PT;Classification code 10011762;Term: Cystic fibrosis;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]		Product Code: QBW251
INN or Proposed INN: Not assigned
Product Code: QBW251
INN or Proposed INN: Not assigned		Novartis Pharma Services AGNULLNot RecruitingFemale: yes
Male: yes		156Phase 1;Phase 2United States;France;Belgium;Ireland;Romania;Netherlands;Germany;United Kingdom

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