DDrare: Database of Drug Development for Rare Diseases

Searched query = "Pemphigus"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = ALXN1830; ARGX-113; Acetaminophen; Acetaminophen/paracetamol; Acetate; Antihistamine (cetirizine or equivalent); Azathioprine; CELLCEPT®; CORTANCYL 20 mg; Carboxymethylcellulose; CellCept 500 mg comprimidos recubiertos; CellCept®500 mg comprimidos; Cellcept® in autoimmune bullous dermatoses; Cellulose; Cetirizine; Cohort 1: 1.0 x 10^8 PolyTregs; Cohort 2: 2.5x10^8 PolyTregs; Combination of Protein A Immunoadsorption, Rituximab, Dexamethasone plus Azathioprine; Cortancyl; Corticosteroids'therapy; Cotton; Cyclophosphamide; DSG3-CAART; Dapsone; Dermoval; Device: Carboxymethylcellulose with ionic silver (Aquacel Ag); Device: Cellulose acetate with petrolatum; Device: Cotton gauze with petrolatum; Device: Nanocrystalline silver (Acticoat); Dexamethasone; Dexamethasone (50mg 1dd6, 3 consecutive days/month); Dexamethasone 0.5mg/5ml solution; Dexamethasone 0.5mg/5ml solution in Mucolox™; EFGARTIGIMOD ALFA; Efgartigimod; Efgartigimod PH20 SC; Efgartigimod alfa; Enbrel (Etanercept); Etanercept; Filgrastim; GLYCINE; GSK1841157; General Corticotherapy; Glycine; Hematopoietic stem cell transplantation; Human interleukin-2; INCB050465; INCB050465 0.3 mg; INCB050465 0.3mg; INCB050465 1.0 mg; INCB050465 1.0mg; INCB050465 2.5mg; INCB050465 HYDROCHLORIDE; INTERLEUKIN-2; IVIg; Ianalumab; Imatinib; Infliximab; Intratect; Intratect 5%; Intravenous immunoglobulin; KC706; MABTHERA; MABTHERA®; MMF; MTX; MabThera; Mabthera; Mabthéra; Mathéra; Methotrexate; Methylprednisolone; Micofenolato mofetilo; Mycophenolate; Mycophenolate Mofetil; Mycophenolate Mofetil (MMF) 3 g/Day; Mycophenolate Mofetil 2 g/Day; Mycophenolate mofetil; OFATUMUMAB; ONO-4059; Ofatumumab; Other: Autologous Platelet rich plasma; Other: IVIg; PI-0824; PREDNISONE; PRN1008; PRN1008 (Rilzabrutinib); PRN1008 Freebase; PRN1008 Oral Tablet; Paracetamol; Parsaclisib; Petrolatum; Prednisolone; Prednisone; Prednisone/Prednisolone; RITUXIMAB; RO0452294/V02; RO1061443/F02; Rapamycin; Recombinant human interleukin-2 (rhIL-2); Rituximab; Rituximab (MABTHERA® or RITUXAN®).; Rituximab and Cyclophosphamide IV; Silver; Sirolimus; Sirolimus (formerly known as Rapamycin); TPM203; Tirabrutinib; Triamcinolone; Triamcinolone Acetonide; VAY736; WATER FOR INJECTION; Water; [NA]

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01974518 (ClinicalTrials.gov)	November 2013	4/10/2013	Comparative Study of Rituximab Versus Combination of Rituximab and Intravenous Cyclophosphamide in Severe Pemphigus	A PILOT STUDY TO ASSESS THE EFFICACY OF RITUXIMAB VERSUS COMBINATION OF RITUXIMAB AND INTRAVENOUS CYCLOPHOSPHAMIDE IN THE TREATMENT OF REFRACTORY PEMPHIGUS	Pemphigus	Drug: Rituximab and Cyclophosphamide IV	Uprety Shraddha	Postgraduate Institute of Medical Education and Research	Active, not recruiting	18 Years	N/A	Both	20	Phase 3	India
2	NCT00483119 (ClinicalTrials.gov)	April 2007	5/6/2007	Randomized Trial of IVIg With or Without Cyclophosphamide in Pemphigus	Phase 2 Randomized Trial of IVIg With or Without Cyclophosphamide in Pemphigus	Pemphigus Vulgaris	Drug: intravenous immunoglobulin;Drug: cyclophosphamide	New York University School of Medicine	NULL	Terminated	18 Years	85 Years	All	9	Phase 2	United States
3	NCT00278642 (ClinicalTrials.gov)	September 2002	16/1/2006	Hematopoietic Stem Cell Support in Patients With Autoimmune Bullous Skin Disorders	High Dose Cyclophosphamide & ATG With Hematopoietic Stem Cell Support in Patients With Autoimmune Bullous Skin Disorders: A Phase I Trial	Pemphigus	Biological: Hematopoietic stem cell transplantation	Richard Burt, MD	NULL	Terminated	18 Years	60 Years	Both	1	Phase 1	United States
4	NCT00010413 (ClinicalTrials.gov)	April 1999	2/2/2001	Phase II Study of High-Dose Cyclophosphamide in Patients With Refractory Pemphigus		Pemphigus	Drug: cyclophosphamide;Drug: filgrastim	Johns Hopkins University	NULL	Completed	18 Years	70 Years	Both	35	Phase 2	United States

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

NCT01974518
(ClinicalTrials.gov)

November 2013

4/10/2013

Comparative Study of Rituximab Versus Combination of Rituximab and Intravenous Cyclophosphamide in Severe Pemphigus

A PILOT STUDY TO ASSESS THE EFFICACY OF RITUXIMAB VERSUS COMBINATION OF RITUXIMAB AND INTRAVENOUS CYCLOPHOSPHAMIDE IN THE TREATMENT OF REFRACTORY PEMPHIGUS

Pemphigus

Drug: Rituximab and Cyclophosphamide IV

Uprety Shraddha

Postgraduate Institute of Medical Education and Research

Active, not recruiting

18 Years

N/A

Both

Phase 3

India

NCT00483119
(ClinicalTrials.gov)

April 2007

5/6/2007

Randomized Trial of IVIg With or Without Cyclophosphamide in Pemphigus

Phase 2 Randomized Trial of IVIg With or Without Cyclophosphamide in Pemphigus

Pemphigus Vulgaris

Drug: intravenous immunoglobulin;Drug: cyclophosphamide

New York University School of Medicine

NULL

Terminated

18 Years

85 Years

All

Phase 2

United States

NCT00278642
(ClinicalTrials.gov)

September 2002

16/1/2006

Hematopoietic Stem Cell Support in Patients With Autoimmune Bullous Skin Disorders

High Dose Cyclophosphamide & ATG With Hematopoietic Stem Cell Support in Patients With Autoimmune Bullous Skin Disorders: A Phase I Trial

Pemphigus

Biological: Hematopoietic stem cell transplantation

Richard Burt, MD

NULL

Terminated

18 Years

60 Years

Both

Phase 1

United States

NCT00010413
(ClinicalTrials.gov)

April 1999

2/2/2001

Phase II Study of High-Dose Cyclophosphamide in Patients With Refractory Pemphigus

Pemphigus

Drug: cyclophosphamide;Drug: filgrastim

Johns Hopkins University

NULL

Completed

18 Years

70 Years

Both

Phase 2

United States