74. Prolactin secreting pituitary adenoma
18 clinical trials, 33 drugs (DrugBank: 10 drugs), 16 drug target genes, 63 drug target pathways
Searched query = "Prolactin secreting pituitary adenoma", "Pituitary PRL secretion hyperthyroidism", "Prolactinoma", "Prolactin secreting adenoma"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT03400865 (ClinicalTrials.gov) | October 25, 2018 | 8/1/2018 | Cabergoline Combined Hydroxychloroquine/Chloroquine to Treat Resistant Prolactinomas | The Effect of Combined Treatment of Cabergoline With Hydroxychloroquine/Chloroquine for Resistant Prolactinomas | Resistance, Disease;Prolactinoma | Drug: HCQ/CQ and CAB combined treatment | Zhebao Wu | Xinqiao Hospital of Chongqing;First Hospital of China Medical University;Beijing Tiantan Hospital;First Affiliated Hospital of Wenzhou Medical University;First Affiliated Hospital of Fujian Medical University;Peking Union Medical College Hospital;Huashan Hospital;Chinese PLA General Hospital | Not yet recruiting | 18 Years | 70 Years | All | 30 | N/A | China |
| 2 | NCT03457389 (ClinicalTrials.gov) | February 22, 2018 | 23/1/2018 | Comparison of Treatment Outcome of Cabergoline According to Target Prolactin Levels in Patients With Prolactinoma | Comparison of Treatment Outcome of Cabergoline According to Target Prolactin Levels in Patients With Prolactinoma: A Prospective, Randomized, Open Label, Active-controlled, Clinical Trial | Pituitary Adenoma;Prolactinoma;Pituitary Tumor;Recurrence Tumor | Drug: Cabergoline | Seoul National University Hospital | NULL | Recruiting | 19 Years | N/A | All | 68 | N/A | Korea, Republic of |
| 3 | NCT01620138 (ClinicalTrials.gov) | March 2010 | 18/9/2011 | Response to Cabergoline and Pasireotide in Non-functioning Pituitary Adenomas and Resistant Prolactinomas | Somatostatin and Dopamine Receptors Expression in Non-functioning Pituitary Adenomas and Resistant Prolactinomas: Correlation With in Vitro and in Vivo Responsiveness to Somatostatin Analogs and Dopamine Agonist | Non-functioning Pituitary Adenomas;Prolactinomas | Drug: Pasireotide;Drug: cabergoline | Universidade Federal do Rio de Janeiro | NULL | Completed | 18 Years | N/A | All | 21 | Phase 2;Phase 3 | Brazil |
| 4 | NCT00460616 (ClinicalTrials.gov) | January 2007 | 13/4/2007 | Cardiac Valve Complications in Prolactinomas Treated With Cabergoline | Observational Study to Investigate the Prevalence of Cardiac Abnormalities and Valvular Regurgitation in Patients With Prolactinomas Treated Chronically With Cabergoline | Prolactinomas | Drug: Cabergoline | Federico II University | NULL | Completed | 18 Years | 65 Years | Both | 50 | Italy |