90. Retinitis pigmentosa
103 clinical trials,   158 drugs   (DrugBank: 42 drugs),   52 drug target genes,   107 drug target pathways

Searched query = "Retinitis pigmentosa", "Rod dystrophy", "Rod-Cone Dystrophy"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
5 trials found
No.TrialIDDate_
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Public_titleScientific_titleConditionInterventionPrimary_
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agemin
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PhaseCountries
1NCT04604899
(ClinicalTrials.gov)
November 202016/10/2020Safety of Repeat Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Adult Subjects With Retinitis PigmentosaA Phase 2 Study of the Safety of Repeat Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Adult Subjects With Retinitis Pigmentosa (RP)Retinitis PigmentosaBiological: human retinal progenitor cellsjCyte, IncCalifornia Institute for Regenerative Medicine (CIRM)Not yet recruiting18 YearsN/AAll30Phase 2United States
2EUCTR2019-004547-77-GB
(EUCTR)
09/06/202026/02/2020Safety and Tolerability of hRPC in Retinitis PigmentosaFirst-in-human Phase I/IIa, Open-Label, Prospective Study of the Safety and Tolerability of Subretinally Transplanted Human Retinal Progenitor Cells (hRPC) in Subjects with Retinitis Pigmentosa (RP) Retinitis Pigmentosa
MedDRA version: 20.0;Level: PT;Classification code 10038914;Term: Retinitis pigmentosa;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Eye Diseases [C11]
Product Name: human Retinal Progenitor Cells Drug Product
Product Code: hRPC DP
INN or Proposed INN: ALLOGENEIC NEURAL RETINA-DERIVED HUMAN NEURAL RETINAL PROGENITOR CELLS EX VIVO EXPANDED
Other descriptive name: ALLOGENEIC NEURAL RETINA-DERIVED HUMAN NEURAL RETINAL PROGENITOR CELLS EX VIVO EXPANDED
ReNeuron LtdNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
33Phase 2United States;United Kingdom
3NCT03073733
(ClinicalTrials.gov)
March 1, 20172/3/2017Safety and Efficacy of Intravitreal Injection of Human Retinal Progenitor Cells in Adults With Retinitis PigmentosaA Prospective, Multicenter, Randomized, Study of the Safety and Efficacy of Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Adult Subjects With Retinitis Pigmentosa (RP)Retinitis PigmentosaBiological: human retinal progenitor cells;Other: Mock injectionjCyte, IncCalifornia Institute for Regenerative Medicine (CIRM)Active, not recruiting18 YearsN/AAll84Phase 2United States
4NCT02464436
(ClinicalTrials.gov)
December 201518/5/2015Safety and Tolerability of hRPC in Retinitis PigmentosaFirst-in-human Phase I/IIa, Open-Label, Prospective Study of the Safety and Tolerability of Subretinally Transplanted Human Retinal Progenitor Cells (hRPC) in Patients With Retinitis Pigmentosa (RP)Retinitis PigmentosaDrug: hRPCReNeuron LimitedNULLRecruiting18 YearsN/AAll33Phase 1;Phase 2United States;United Kingdom
5NCT02320812
(ClinicalTrials.gov)
June 201516/12/2014Safety of a Single, Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Retinitis PigmentosaA Prospective, Multicenter, Open-Label, Single-Arm Study of the Safety and Tolerability of a Single, Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Adult Subjects With Retinitis Pigmentosa (RP)Retinitis Pigmentosa (RP)Biological: human retinal progenitor cellsjCyte, IncCalifornia Institute for Regenerative Medicine (CIRM)Completed18 YearsN/AAll28Phase 1;Phase 2United States