90. Retinitis pigmentosa
103 clinical trials,   158 drugs   (DrugBank: 42 drugs),   52 drug target genes,   107 drug target pathways
Searched query = "Retinitis pigmentosa", "Rod dystrophy", "Rod-Cone Dystrophy"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | NCT04604899 (ClinicalTrials.gov) | November 2020 | 16/10/2020 | Safety of Repeat Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Adult Subjects With Retinitis Pigmentosa | A Phase 2 Study of the Safety of Repeat Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Adult Subjects With Retinitis Pigmentosa (RP) | Retinitis Pigmentosa | Biological: human retinal progenitor cells | jCyte, Inc | California Institute for Regenerative Medicine (CIRM) | Not yet recruiting | 18 Years | N/A | All | 30 | Phase 2 | United States |
2 | EUCTR2019-004547-77-GB (EUCTR) | 09/06/2020 | 26/02/2020 | Safety and Tolerability of hRPC in Retinitis Pigmentosa | First-in-human Phase I/IIa, Open-Label, Prospective Study of the Safety and Tolerability of Subretinally Transplanted Human Retinal Progenitor Cells (hRPC) in Subjects with Retinitis Pigmentosa (RP) | Retinitis Pigmentosa MedDRA version: 20.0;Level: PT;Classification code 10038914;Term: Retinitis pigmentosa;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Eye Diseases [C11] | Product Name: human Retinal Progenitor Cells Drug Product Product Code: hRPC DP INN or Proposed INN: ALLOGENEIC NEURAL RETINA-DERIVED HUMAN NEURAL RETINAL PROGENITOR CELLS EX VIVO EXPANDED Other descriptive name: ALLOGENEIC NEURAL RETINA-DERIVED HUMAN NEURAL RETINAL PROGENITOR CELLS EX VIVO EXPANDED | ReNeuron Ltd | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 33 | Phase 2 | United States;United Kingdom | ||
3 | NCT03073733 (ClinicalTrials.gov) | March 1, 2017 | 2/3/2017 | Safety and Efficacy of Intravitreal Injection of Human Retinal Progenitor Cells in Adults With Retinitis Pigmentosa | A Prospective, Multicenter, Randomized, Study of the Safety and Efficacy of Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Adult Subjects With Retinitis Pigmentosa (RP) | Retinitis Pigmentosa | Biological: human retinal progenitor cells;Other: Mock injection | jCyte, Inc | California Institute for Regenerative Medicine (CIRM) | Active, not recruiting | 18 Years | N/A | All | 84 | Phase 2 | United States |
4 | NCT02464436 (ClinicalTrials.gov) | December 2015 | 18/5/2015 | Safety and Tolerability of hRPC in Retinitis Pigmentosa | First-in-human Phase I/IIa, Open-Label, Prospective Study of the Safety and Tolerability of Subretinally Transplanted Human Retinal Progenitor Cells (hRPC) in Patients With Retinitis Pigmentosa (RP) | Retinitis Pigmentosa | Drug: hRPC | ReNeuron Limited | NULL | Recruiting | 18 Years | N/A | All | 33 | Phase 1;Phase 2 | United States;United Kingdom |
5 | NCT02320812 (ClinicalTrials.gov) | June 2015 | 16/12/2014 | Safety of a Single, Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Retinitis Pigmentosa | A Prospective, Multicenter, Open-Label, Single-Arm Study of the Safety and Tolerability of a Single, Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Adult Subjects With Retinitis Pigmentosa (RP) | Retinitis Pigmentosa (RP) | Biological: human retinal progenitor cells | jCyte, Inc | California Institute for Regenerative Medicine (CIRM) | Completed | 18 Years | N/A | All | 28 | Phase 1;Phase 2 | United States |