97. Ulcerative colitis
2,269 clinical trials,   1,331 drugs   (DrugBank: 241 drugs),   114 drug target genes,   181 drug target pathways

Searched query = "Ulcerative colitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
65 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
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size
PhaseCountries
1NCT04505410
(ClinicalTrials.gov)
November 18, 20205/8/2020A Fasting Mimicking Diet on Ulcerative Colitis Patients Undergoing Tofacitinib InductionA Randomized Control Study to Examine the Influence of a Fasting Mimicking Diet on Moderate to Severe Ulcerative Colitis Patients Undergoing Tofacitinib InductionUlcerative ColitisDrug: Tofacitinib;Other: Fast Mimicking DietUniversity of MiamiPfizerRecruiting18 YearsN/AAll76Phase 3United States
2JPRN-UMIN000041972
2020/10/0101/10/2020Clinical trial on the effects of dietary intake of sulforaphane-rich broccoli sprouts on severity of ulcerative colitis.Clinical trial on the effects of dietary intake of sulforaphane-rich broccoli sprouts on severity of ulcerative colitis. - BS-UC-2020 ulcerative colitisBroccoli Sprouts (20 g/day, 8 weeks)
Alfalfa Sprouts (20 g/day, 8 weeks)
University of TsukubaNULLRecruiting20years-oldNot applicableMale and Female50Not selectedJapan
3NCT04223518
(ClinicalTrials.gov)
September 20, 20206/1/2020Serum Bovine Immunoglobulin (SBI) in Children and Young Adults With Inflammatory Bowel Disease (IBD)Safety, Tolerability, and Nutritional Impact of Serum Bovine Immunoglobulin (SBI) in Children and Young Adults With Inflammatory Bowel DiseaseInflammatory Bowel Diseases;Ulcerative Colitis;Crohn DiseaseDietary Supplement: Serum bovine immunoglobulin;Dietary Supplement: PlaceboMonisha Hitesh ShahNULLRecruiting6 Years30 YearsAll43Early Phase 1United States
4NCT03980405
(ClinicalTrials.gov)
September 20205/6/2019Combination of Diet and 5ASA ( 5-aminosalicylic Acid) for Ulcerative ColitisCombination Therapy With Drug and Diet for Induction of Remission in Mild to Moderate Active Pediatric Ulcerative Colitis: A Single Blinded, International Randomized Controlled TrialUlcerative ColitisDietary Supplement: Group 1- Control Diet;Dietary Supplement: Group 2- UCD DietProf. Arie LevineNULLNot yet recruiting10 Years19 YearsAll62N/ANULL
5NCT04331639
(ClinicalTrials.gov)
September 202023/3/2020High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Biologic TherapyImplementation of High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Infliximab or VedolizumabInflammatory Bowel Disease;Crohn Disease;Ulcerative Colitis;Vitamin D DeficiencyDietary Supplement: vitamin D3Boston Children's HospitalNULLNot yet recruiting5 Years25 YearsAll50Phase 2NULL
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
6NCT04332328
(ClinicalTrials.gov)
April 1, 202031/3/2020Study of Demographic and Dietary Profile in Patients With Ulcerative Colitis in Upper EgyptStudy of Demographic and Dietary Profile in Patients With Ulcerative Colitis in Upper EgyptDiet in Ulcerative Colitis PatientsDietary Supplement: DietAssiut UniversityNULLNot yet recruitingN/AN/AAll50NULL
7NCT04225819
(ClinicalTrials.gov)
April 1, 20203/1/2020Adjunctive Treatment With Vitamin D3 in Patients With Active IBDAdjunctive Treatment With Vitamin D3 in Patients With Active IBD (ACTIVATED): A Randomized, Double-blind, Placebo-controlled TrialIBD;Inflammatory Bowel Diseases;Crohn Disease;Ulcerative Colitis;Vitamin D3 DeficiencyDietary Supplement: Vitamin D3;Other: PlaceboMassachusetts General HospitalNULLNot yet recruiting18 YearsN/AAll100N/ANULL
8NCT04276740
(ClinicalTrials.gov)
April 1, 202012/2/2020MARVEL: Mitochondrial Anti-oxidant Therapy to Resolve Inflammation in Ulcerative ColitisMitochondrial Anti-oxidant Therapy to Resolve Inflammation in Ulcerative Colitis (MARVEL): A Randomised Placebo-controlled Trial on Oral MitoQ in Moderate UCUlcerative Colitis FlareDietary Supplement: MitoQ;Other: PlaceboUniversity of EdinburghJP Moulton Charitable Foundation;MitoQNot yet recruiting18 YearsN/AAll206Phase 2NULL
9NCT04188990
(ClinicalTrials.gov)
March 5, 20202/12/2019Cost Effectiveness of an Intervention in Hospitalized Patients With Disease-related MalnutritionEvaluation of the Effectiveness and Cost Effectiveness of an Intervention in Hospitalized Patients With Disease-related MalnutritionPancreatitis, Acute;Crohn Disease;Ulcerative Colitis;Inflammatory Bowel Diseases;Pancreatic Cancer;Esophagus Cancer;Gastric Cancer;Colorectal CancerDietary Supplement: Nutritional dietary intervention;Dietary Supplement: By demand;Dietary Supplement: Usual current careHospital Galdakao-UsansoloNULLNot yet recruiting18 YearsN/AAll900N/ANULL
10NCT02277223
(ClinicalTrials.gov)
March 1, 202025/10/2014Curcumin in Pediatric Ulcerative ColitisCurcumin for Induction and Maintenance Therapy in Pediatric Ulcerative ColitisUlcerative ColitisDietary Supplement: Curcumin;Drug: PlaceboSchneider Children's Medical Center, IsraelNULLRecruiting6 Years18 YearsAll60Phase 3Israel
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
11EUCTR2019-003220-21-GB
(EUCTR)
26/02/202012/12/2019Management of diarrhoea in ulcerative colitis: multi-arm multi stage trial of low FODMAP diet, amitriptyline, ondansetron, or loperamide: MODULATE.Management of diarrhoea in ulcerative colitis: multi-arm multi-stage trial of low FODMAP diet, amitriptyline, ondansetron, or loperamide: MODULATE. - MODULATE Diarrhoea in patients with stable ulcerative colitis.
MedDRA version: 20.1;Level: LLT;Classification code 10045365;Term: Ulcerative colitis;System Organ Class: 100000004856
MedDRA version: 20.1;Classification code 10033007;Term: Other ulcerative colitis;Classification code 10066557;Term: Chronic diarrhoea;System Organ Class: 100000004856;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Trade Name: Amitriptyline
Product Name: Amitriptyline
INN or Proposed INN: Amitriptyline hydrochloride
Product Name: Ondansetron
INN or Proposed INN: Ondansetron hydrochloride dihydrate
Product Name: Loperamide
INN or Proposed INN: loperamide hydrochloride
University of LeedsNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
491Phase 2;Phase 3United Kingdom
12NCT04241029
(ClinicalTrials.gov)
February 25, 202017/1/2020Boosting Biologics in UCBoosting Biologics in Ulcerative ColitisUlcerative Colitis;Inflammatory Bowel DiseasesDietary Supplement: IDOFORM®TravelOslo University HospitalHelse Sor-OstRecruiting18 Years75 YearsAll20Phase 1Norway
13NCT03998488
(ClinicalTrials.gov)
January 31, 202024/6/2019Examining the Efficacy of Fecal Microbiota Transplantation (FMT) and Dietary Fiber in Patients With Ulcerative ColitisA Randomized, Placebo-controlled Clinical Trial Examining the Efficacy of Fecal Microbiota Transplantation (FMT) and Subsequent Dietary Fiber in Patients With Moderate Ulcerative ColitisUlcerative Colitis;Inflammatory Bowel DiseasesDrug: Fecal Microbiota Transplantation;Dietary Supplement: Psyllium Husk PowderWeill Medical College of Cornell UniversityCrohn's and Colitis FoundationRecruiting18 Years89 YearsAll135Phase 2United States
14EUCTR2018-005086-39-HR
(EUCTR)
16/12/201917/01/2020A Randomized, Placebo-Controlled, Double-Blind, Multicenter Study to Evaluate Efficacyand Safety of Oral BT-11 in Mild to Moderate Ulcerative ColitisA Randomized, Placebo-Controlled, Double-Blind, Multicenter Study to Evaluate Efficacy and Safety of Oral BT-11 in Mild to Moderate Ulcerative Colitis Mild to Moderate Ulcerative Colitis Inflammatory bowel disease (IBD) is an autoimmune disease of the gastrointestinal (GI) tract with unknown etiology that encompasses 2 primary clinical manifestations: ulcerative colitis (UC) and Crohn’s disease (CD). UC manifests through complex interactions between the gut microbiome, dysregulated immune responses, genetic mutations, diet, and other environmental factors.
MedDRA version: 20.0;Level: PT;Classification code 10009900;Term: Colitis ulcerative;System Organ Class: 10017947 - Gastrointestinal disorders
MedDRA version: 20.1;Level: LLT;Classification code 10045365;Term: Ulcerative colitis;System Organ Class: 10017947 - Gastrointestinal disorders;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Name: BT-11 500 mg
Product Code: BT-11
INN or Proposed INN: to be requested
Other descriptive name: BT-11
Product Name: BT-11 1000mg
Product Code: BT-11
INN or Proposed INN: to be requested
Other descriptive name: BT-11
Landos Biopharma Inc.NULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
195Phase 2Belarus;Serbia;United States;Ukraine;Russian Federation;Hungary;Canada;Poland;Croatia;Bulgaria;Georgia;Moldova, Republic of;Bosnia and Herzegovina
15EUCTR2018-005086-39-HU
(EUCTR)
28/10/201908/04/2019A Randomized, Placebo-Controlled, Double-Blind, Multicenter Study to Evaluate Efficacyand Safety of Oral BT-11 in Mild to Moderate Ulcerative ColitisA Randomized, Placebo-Controlled, Double-Blind, Multicenter Study to Evaluate Efficacyand Safety of Oral BT-11 in Mild to Moderate Ulcerative Colitis Mild to Moderate Ulcerative Colitis Inflammatory bowel disease (IBD) is an autoimmune disease of the gastrointestinal (GI) tract with unknown etiology that encompasses 2 primary clinical manifestations: ulcerative colitis (UC) and Crohn’s disease (CD). UC manifests through complex interactions between the gut microbiome, dysregulated immune responses, genetic mutations, diet, and other environmental factors.
MedDRA version: 20.0;Level: PT;Classification code 10009900;Term: Colitis ulcerative;System Organ Class: 10017947 - Gastrointestinal disorders
MedDRA version: 20.1;Level: LLT;Classification code 10045365;Term: Ulcerative colitis;System Organ Class: 10017947 - Gastrointestinal disorders;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Code: BT-11
INN or Proposed INN: to be requested
Product Code: BT-11
INN or Proposed INN: to be requested
Landos Biopharma Inc.NULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
195Phase 2United States;Serbia;Belarus;Hungary;Poland;Ukraine;Croatia;Russian Federation;Georgia;Moldova, Republic of;Bosnia and Herzegovina
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
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size
PhaseCountries
16EUCTR2018-005086-39-PL
(EUCTR)
07/10/201906/05/2019A Study to Evaluate Efficacy and Safety of BT-11 product oral tablets in Mild to Moderate Ulcerative ColitisA Randomized, Placebo-Controlled, Double-Blind, Multicenter Study to Evaluate Efficacy and Safety of Oral BT-11 in Mild to Moderate Ulcerative Colitis Mild to Moderate Ulcerative Colitis Inflammatory bowel disease (IBD) is an autoimmune disease of the gastrointestinal (GI) tract with unknown etiology that encompasses 2 primary clinical manifestations: ulcerative colitis (UC) and Crohn’s disease (CD). UC manifests through complex interactions between the gut microbiome, dysregulated immune responses, genetic mutations, diet, and other environmental factors.
MedDRA version: 20.0;Level: PT;Classification code 10009900;Term: Colitis ulcerative;System Organ Class: 10017947 - Gastrointestinal disorders
MedDRA version: 20.1;Level: LLT;Classification code 10045365;Term: Ulcerative colitis;System Organ Class: 10017947 - Gastrointestinal disorders;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Name: BT-11 500 mg
Product Code: BT-11
INN or Proposed INN: to be requested
Other descriptive name: BT-11
Product Name: BT-11 1000mg
Product Code: BT-11
INN or Proposed INN: to be requested
Other descriptive name: BT-11
Landos Biopharma Inc.NULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
195Phase 2United States;Serbia;Belarus;Hungary;Poland;Ukraine;Croatia;Russian Federation;Georgia;Moldova, Republic of;Bosnia and Herzegovina
17NCT04006977
(ClinicalTrials.gov)
October 20191/7/2019Multistrain Probiotics Reduces UC Depression and Anxiety ScoresMultistrain Probiotic Product (De Simone Formulation) Reduces Depression and Anxiety Scores: a Randomized Pilot Study in Patients With Ulcerative ColitisUlcerative ColitisDietary Supplement: a multistrain probiotic product (DSF);Dietary Supplement: PlaceboXijing Hospital of Digestive DiseasesMENDES SANot yet recruiting18 Years65 YearsAll60N/AChina
18NCT04102852
(ClinicalTrials.gov)
September 30, 201917/9/2019Lactobacillus Rhamnosus GG (ATCC 53103) in Mild-moderately Active UC PatientsThe Role of Lactobacillus Rhamnosus GG (ATCC 53103) in the Modulation of the Inflammatory Process in the Mucosa of Ulcerative Colitis (UC) Patients With Mild-moderate Clinical ActivityUlcerative Colitis Chronic Mild;Ulcerative Colitis Chronic ModerateDietary Supplement: Lactobacillus rhamnosus GG ATCC 53103San Giovanni Addolorata HospitalOnlus S. AndreaRecruiting18 Years65 YearsAll80Phase 1;Phase 2Italy
19NCT03847467
(ClinicalTrials.gov)
September 20, 201912/2/2019Pilot and Feasibility Study of 2'-FL as a Dietary Supplement in IBD Patients Receiving Stable Maintenance Anti-TNF TherapyPilot and Feasibility Study of 2'-FL as a Dietary Supplement in Pediatric and Young Adult IBD Patients Receiving Stable Maintenance Anti-TNF TherapyInflammatory Bowel Diseases;Crohn Disease;Ulcerative ColitisDrug: 2'-Fucosyllactose;Other: PlaceboChildren's Hospital Medical Center, CincinnatiBroad Institute;University of Cincinnati;Connecticut Children's Medical CenterRecruiting11 Years25 YearsAll216Phase 1;Phase 2United States
20NCT03941418
(ClinicalTrials.gov)
June 1, 20195/5/2019Impact of Additional Treatment With Saccharomyces Boulardii on Quality of Life in Patients With Mild Forms of Ulcerative Colitis and Crohn DiseaseImpact of Additional Treatment With Saccharomyces Boulardii on Quality of Life in Patients With Mild Forms of Ulcerative Colitis and Crohn DiseaseUlcerative Colitis;Crohn DiseaseDietary Supplement: Boulardii;Dietary Supplement: PlaceboUniversity Clinic Dr Dragisa Misovic-DedinjeUniversity Clinic ZvezdaraNot yet recruiting18 Years80 YearsAll150N/ANULL
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
21NCT03720002
(ClinicalTrials.gov)
May 29, 201921/10/2018HF2 Therapy in the Treatment of Active Ulcerative ColitisHF2 Therapy in the Treatment of Active Ulcerative Colitis:Ulcerative ColitisDietary Supplement: HF2Sheba Medical CenterNULLRecruiting18 Years70 YearsAll34Phase 1;Phase 2Israel
22NCT02201758
(ClinicalTrials.gov)
December 201818/7/2014Flaxseed Lignan-Enriched Complex (FLC) for the Treatment of Patients With Ulcerative Colitis (UC): A Pilot AssessmentFlaxseed Lignan-enriched Complex (FLC) for the Treatment of Patients With Mild to Moderately Severe Ulcerative Colitis (UC): A Pilot Assessment.Ulcerative ColitisDietary Supplement: Flaxseed lignan-enriched complex (FLC);Other: PlaceboUniversity of SaskatchewanRoyal University Hospital FoundationUnknown status18 YearsN/AAll56Phase 2Canada
23NCT02469220
(ClinicalTrials.gov)
July 1, 20188/6/2015Diet Treatment of Patients With Ulcerative Colitis in RemissionDiet Treatment of Patients With Ulcerative Colitis in RemissionUlcerative ColitisDietary Supplement: Low FODMAP;Dietary Supplement: Standardized FODMAPVendsyssel HospitalNULLActive, not recruiting18 Years70 YearsAll19N/ADenmark
24NCT04329481
(ClinicalTrials.gov)
June 12, 201829/3/2020The Effect of Mycobiome Supplementation on Gastrointestinal Symptoms in IBD PatientsThe Effect of Mycobiome Supplementation on Gastrointestinal Symptoms in IBD PatientsUlcerative Colitis;Crohn Disease;Inflammatory Bowel DiseasesDietary Supplement: Mycodigest supplementTel-Aviv Sourasky Medical CenterNULLRecruiting18 Years70 YearsAll100N/AIsrael
25NCT03594708
(ClinicalTrials.gov)
April 30, 201819/1/2018Immunonutrition in Ulcerative ColitisImpact of Immunonutrition Supplementation Combining Fermentable Fiber, Omega-3 Fatty Acids, Vitamin D, Vitamin E, and Zinc on Intestinal Inflammation, Gut Microbial Activity, and Severity of Symptoms in Ulcerative Colitis PatientsUlcerative ColitisDietary Supplement: Nutrition supplement;Dietary Supplement: Placebo supplementBaptist Memorial Health Care CorporationNULLUnknown status18 YearsN/AAll30N/AUnited States
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
26NCT03444311
(ClinicalTrials.gov)
March 8, 20188/2/2018Combined Nutritional Therapies for the Treatment of Ulcerative ColitisDevelopment of Combined Nutritional Therapies for the Treatment of Ulcerative Colitis Through the Increase of the Biodiversity of the Microbiota.Colitis, UlcerativeDietary Supplement: A: 1 dosis;Dietary Supplement: B: 2 dosisAB Biotics, SANULLTerminated18 Years65 YearsAll12N/ASpain
27NCT03309865
(ClinicalTrials.gov)
December 25, 20177/10/2017Evaluating the Combined Effect of Vedolizumab and Semi-Vegetarian Diet on Ulcerative Colitis.A Pilot Study Evaluating the Synergistic Effect of Vedolizumab in Conjunction With Structured Semi-Vegetarian Diet on the Treatment of Ulcerative Colitis.Ulcerative Colitis;Dietary ModificationDietary Supplement: semi-vegetarian diet;Drug: Vedolizumab InjectionMayo ClinicNULLWithdrawn18 YearsN/AAll0Early Phase 1United States
28NCT03266484
(ClinicalTrials.gov)
November 13, 201725/8/2017Effect of a Probiotic Mixture on the Gut Microbiome and Fatigue in Patients With Quiescent Inflammatory Bowel DiseaseEffect of Dietary Therapy With a Probiotic Mixture on the Gut Microbiome and Fatigue Symptoms in Patients With Quiescent Inflammatory Bowel Disease - A Clinical TrialInflammatory Bowel Diseases;Crohn Disease;Ulcerative ColitisDietary Supplement: Probiotic Mixture;Dietary Supplement: PlaceboMassachusetts General HospitalWinclove Bio Industries BVRecruiting18 Years75 YearsAll100N/AUnited States
29NCT03122613
(ClinicalTrials.gov)
June 19, 20177/4/2017Curcumin for Prevention of Relapse in Patients With Ulcerative ColitisA Double-blind, Randomized, Placebo-Controlled Trial of Curcumin Versus Placebo for Prevention of Relapse in Patients With Ulcerative ColitisUlcerative Colitis in RemissionDietary Supplement: Curcumin;Drug: PlaceboChinese University of Hong KongNULLRecruiting18 YearsN/AAll172N/AHong Kong
30NCT03415711
(ClinicalTrials.gov)
April 28, 20175/1/2018PRObiotic VSL#3® for Maintenance of Clinical and Endoscopic REMission in Ulcerative ColitisA Double-blind, Randomized, Placebo-controlled, Single-center, Dose-finding, Pilot Study Evaluating the Efficacy of VSL#3® in the Maintenance of Clinical and Endoscopic Remission of Mild-to-moderate UCUlcerative ColitisDietary Supplement: VSL#3®;Drug: Mesalamine;Drug: PlaceboVSL PharmaceuticalsActial Farmaceutica S.r.l.Terminated18 Years85 YearsAll14N/AItaly
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
31NCT03000101
(ClinicalTrials.gov)
January 19, 201719/12/2016Study of the Role of Pomegranate Juice Ellagitannins in the Modulation of Inflammation in Inflammatory Bowel DiseaseNew Insight and Knowledge on Anti-inflammatory Effectiveness of Dietary Phenolics (NIKE)Crohn's Disease;Ulcerative ColitisOther: 100% pomegranate juice;Other: placebo beverageAzienda Ospedaliera Universitaria di Bologna Policlinico S. Orsola MalpighiUniversity of Bologna;Conserve Italia;GAT FoodsActive, not recruiting18 Years80 YearsAll18N/AItaly
32NCT03798210
(ClinicalTrials.gov)
January 1, 20177/1/2019Lactobacillus Reuteri ATCC PTA 4659 in Ulcerative ColitisThe Effect of Lactobacillus Reuteri ATCC PTA 4659 in Patients With Ulcerative ColitisUlcerative Colitis FlareDietary Supplement: Lactobacillus reuteri;Dietary Supplement: PlaceboUppsala UniversityNULLRecruiting18 Years80 YearsAll40Phase 2Sweden
33NCT03136419
(ClinicalTrials.gov)
October 31, 20165/4/2017Microbiota and Immune microEnvironment in PouchitisMicrobiota and Immune microEnvironment in Pouchitis: Randomized Controlled Trial Oral Administration of Lactobacillus Casei DG After Ileostomy Closure in Ileal Pouch MucosaPouchitis;Ulcerative Colitis;Ileal PouchDietary Supplement: Lactobacillus casei DG;Dietary Supplement: PlaceboUniversity of PadovaNULLRecruiting18 Years100 YearsAll32N/AItaly
34NCT02825914
(ClinicalTrials.gov)
September 1, 201630/6/2016CAsein GLycomacropeptide in Ulcerative Colitis - Anti-Inflammatory and Microbiome Modulating Effects (CAGLUCIM)CAsein GLycomacropeptide in Ulcerative Colitis - Anti-Inflammatory and Microbiome Modulating Effects (CAGLUCIM)Colitis, Ulcerative;Inflammatory Bowel DiseasesDietary Supplement: Casein glycomacropeptide (CGMP);Dietary Supplement: PlaceboUniversity of AarhusNULLCompleted18 YearsN/AAll80N/ADenmark
35NCT02865707
(ClinicalTrials.gov)
August 201612/7/2016Ulcerative Colitis Relapse Prevention by PrebioticsPrevention of Ulcerative Colitis by Prebiotics: Efficacy and Protective MechanismsUlcerative ColitisDietary Supplement: Synergy-1;Dietary Supplement: MaltodextrinUniversity of AlbertaUniversity of British ColumbiaRecruiting18 Years75 YearsAll100N/ACanada
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
36NCT02683733
(ClinicalTrials.gov)
February 201610/2/2016Bio-enhanced Curcumin as an Add-On Treatment in Mild to Moderate Ulcerative ColitisThe Efficacy and Tolerability of Bio-enhanced Curcumin (Diferuloylmethane) in the Induction of Remission in Patients With Mild to Moderate Ulcerative ColitisUlcerative ColitisDietary Supplement: Bio-enhanced Curcumin Soft Gelatin Capsule;Drug: 5-Aminosalicylic acidAsian Institute of Gastroenterology, IndiaNULLRecruiting18 Years70 YearsBoth50Phase 3India
37NCT02683759
(ClinicalTrials.gov)
February 201610/2/2016Bio-enhanced Curcumin as an Add-on Treatment in Maintaining Remission of Ulcerative ColitisThe Efficacy and Tolerability of Bio-Enhanced Curcumin in Maintaining Remission in Patients With Ulcerative ColitisUlcerative ColitisDietary Supplement: Bio-enhanced Curcumin Soft Gelatin Capsule;Drug: 5-Aminosalicyclic acidAsian Institute of Gastroenterology, IndiaNULLRecruiting18 Years70 YearsBoth50Phase 3India
38NCT02345733
(ClinicalTrials.gov)
September 201519/1/2015Use of a Novel Diet (UC DIET) for Treatment of Mild to Moderate Active Pediatric Ulcerative ColitisUse of a Novel Diet (UC DIET) Targeting the Microbiota for Treatment of Mild to Moderate Active Pediatric Ulcerative Colitis: An Open Label Pilot StudyUlcerative Colitis (UC)Other: Ulcerative Colitis Diet;Drug: Antibiotic cocktailProf. Arie LevineNULLRecruiting8 Years19 YearsAll20Phase 4United States;Canada;Israel
39NCT02084550
(ClinicalTrials.gov)
September 20155/3/2014Amino Acids in Ileal Pouch-anal Anastomosis for Ulcerative ColitisAmino Acids in Ileal Pouch-anal Anastomosis for Ulcerative Colitis: a Randomized, Assessor-blinded, Placebo-controlled TrialUlcerative ColitisDietary Supplement: Vaminolac;Other: SalineAarhus University HospitalNULLActive, not recruiting18 Years50 YearsAll8N/ADenmark
40NCT02361957
(ClinicalTrials.gov)
November 201415/1/2015The Effect of the Multispecies Probiotic Ecologic 825 Versus Placebo in Ulcerative Colitis PatientsThe Effect of the Multispecies Probiotic Ecologic 825 Versus Placebo in Ulcerative Colitis PatientsUlcerative ColitisDietary Supplement: Ecologic 825;Dietary Supplement: PlaceboWageningen UniversityNULLSuspended18 Years65 YearsBoth40N/ANetherlands
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
41NCT02217722
(ClinicalTrials.gov)
October 201420/7/2014Use of the Ulcerative Colitis Diet for Induction of RemissionAn Open Label Non Randomized Pilot Study: Use of the Ulcerative Colitis Diet for Induction of Remission.Ulcerative Colitis (UC)Other: Ulcerative Colitis Diet;Drug: Antibiotic cocktailProf. Arie LevineNULLTerminated5 Years18 YearsBoth9N/AIsrael
42NCT02179372
(ClinicalTrials.gov)
June 201429/6/2014Eicosapentaenoic Free Fatty Acid and Fecal Calprotectin in Inflammatory Bowel DiseasesModulation of Fecal Calprotectin by Eicosapentaenoic Free Fatty Acid in Inflammatory Bowel DiseasesUlcerative Colitis;Crohn's DiseaseDietary Supplement: Eicosapentaenoic acid;Dietary Supplement: Medium chain fatty acid (placebo)Azienda Ospedaliera Universitaria di Bologna Policlinico S. Orsola MalpighiNULLCompleted18 Years80 YearsBoth60N/AItaly
43NCT01765439
(ClinicalTrials.gov)
February 20147/1/2013The Effect of VSL#3 Probiotic Preparation on the Bile Acid Metabolism in Patients With Inflammatory Bowel DiseaseThe Effect of VSL#3 (Original De Simone Formulation) Probiotic Preparation on the Bile Acid Metabolism in Patients With Inflammatory Bowel DiseaseCrohn Disease;Ulcerative ColitisDietary Supplement: VSL#3 (Original De Simone formulation)Charles University, Czech RepublicIscare i.v.f., Czech Republic;CD Investments srl;University Of Perugia;University of Roma La SapienzaActive, not recruitingN/AN/AAll79N/ACzechia;Czech Republic
44NCT02069561
(ClinicalTrials.gov)
January 201419/2/2014Effects of Eicosapentaenoic Acid on Subjects at High Risk for Colorectal CancerEffects of Eicosapentaenoic Acid on Molecular, Metabonomics and Intestinal Microbiota Changes, in Subjects With Long-standing Inflammatory Bowel DiseaseUlcerative ColitisDietary Supplement: Eicosapentaenoic AcidAzienda Ospedaliera Universitaria di Bologna Policlinico S. Orsola MalpighiNULLCompleted18 Years70 YearsBoth25N/AItaly
45NCT01771224
(ClinicalTrials.gov)
January 201316/1/2013Effect of FAn-7 in UC ActivityEffect of Palmitoleic Acid (FAn-7) on Expression of HNF4? and Ulcerative Colitis (UC) ActivityInflammatory Bowel Disease;Ulcerative ColitisDietary Supplement: Palmitoleic acidNational Institute of Medical Sciences and Nutrition, Salvador ZubiranNULLRecruiting18 Years59 YearsBoth20Phase 0Mexico
No.TrialIDDate_
enrollment
Date_
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Public_titleScientific_titleConditionInterventionPrimary_
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agemin
Inclusion_
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size
PhaseCountries
46NCT01078935
(ClinicalTrials.gov)
December 20121/3/2010The Effect of Probiotics on the Rate of Recovery of Inflammatory Bowel Disease Exacerbation, Endothelial Function, and Markers of InflammationThe Effect of Probiotics on Bowel DiseaseCrohn's Disease;Ulcerative ColitisDietary Supplement: probiotics;Dietary Supplement: placeboThe Baruch Padeh Medical Center, PoriyaMinistry of Health, IsraelNot yet recruiting18 Years80 YearsBoth100Phase 4NULL
47NCT01783119
(ClinicalTrials.gov)
August 201231/1/2013Effect of Aloe Vera in the Inflammation of Patients With Mild Ulcerative ColitisEffect of Aloe Vera in the Inflammation of Patients With Mild Ulcerative ColitisUlcerative ColitisDietary Supplement: Aloe Barbadensis Miller;Dietary Supplement: placebo waterNational Institute of Medical Sciences and Nutrition, Salvador ZubiranNULLRecruiting18 Years59 YearsBoth60Phase 0Mexico
48NCT01877577
(ClinicalTrials.gov)
April 201211/6/2013Supplementation of Vitamin D3 in Patients With Inflammatory Bowel Diseases and Hypovitaminosis DSupplementation of Vitamin D3 (Cholecalciferol) in Patients With Inflammatory Bowel Diseases (IBD) and Hypovitaminosis D: A Prospective Randomized Controlled Trial.Crohn's Disease (CD);Ulcerative Colitis (UC)Dietary Supplement: Vitamin D3University of California, San FranciscoNULLCompleted18 YearsN/ABoth30N/AUnited States
49NCT01496053
(ClinicalTrials.gov)
December 201115/12/2011Anti-inflammatory Effect of Agaricus Blazei Murill in Inflammatory Bowel Disease (IBD)Anti-inflammatory Effect of a Mushroom Extract (AndoSan)in Patients With Inflammatory Bowel Disease. A Prospective StudyUlcerative Colitis;Crohn's Disease;Inflammatory Bowel DiseaseDietary Supplement: AndoSan;Dietary Supplement: Sugar ExtractOslo University HospitalImmunoPharma ASCompleted18 Years60 YearsAll100Phase 2;Phase 3Norway
50NCT01320436
(ClinicalTrials.gov)
July 201121/3/2011Curcumin + Aminosalicylic Acid (5ASA) Versus 5ASA Alone in the Treatment of Mild to Moderate Ulcerative ColitisRandomized, Double-blind, Placebo-controlled Study to Evaluated the Efficacy of Combining Curcumin+5ASA Medication Versus 5ASA Medication Alone on Active Mild to Moderate Ulcerative Colitis PatientsUlcerative ColitisDietary Supplement: Curcumin;Drug: 5-aminosalicylic acidSheba Medical CenterNULLCompleted18 Years70 YearsBoth50Phase 3Israel
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
51NCT01065571
(ClinicalTrials.gov)
January 20104/2/2010Effects of Carrageenan-Elimination Diet on Ulcerative Colitis Disease ActivityEffects of Carrageenan-Elimination Diet on Ulcerative Colitis Disease ActivityUlcerative ColitisDietary Supplement: carrageenan;Other: dietary intervention with no-carrageenan dietUniversity of Illinois at ChicagoThe Broad Foundation;University of ChicagoCompleted18 YearsN/AAll15N/AUnited States
52NCT00790478
(ClinicalTrials.gov)
January 200912/11/2008Melatonin & Ulcerative ColitisMelatonin and Ulcerative Colitis: A Pilot Clinical TrialUlcerative ColitisDietary Supplement: Melatonin;Other: PlaceboEmory UniversityNULLRecruiting18 Years69 YearsBoth60Phase 2United States
53NCT00793130
(ClinicalTrials.gov)
November 200816/11/2008The Efficacy and Tolerability of Coltect as Add-on in Patients With Active Ulcerative Colitis - an Open LabelThe Efficacy and Tolerability of Coltect as Add-on in Patients With Active Ulcerative Colitis - an Open LabelUlcerative ColitisDietary Supplement: ColtectTel-Aviv Sourasky Medical CenterNULLRecruiting18 Years75 YearsBoth30N/AIsrael
54NCT00751933
(ClinicalTrials.gov)
October 200811/9/2008Vaccines and Dietary Oats in the Treatment of Ulcerative ColitisA Controlled Study of Salmonella Ty21a and Cholera/ ETEC-vaccine and the Role of Oats in Daily Diet as a New Treatment in Patients With Mild or Moderate Ulcerative Colitis.Ulcerative ColitisBiological: Vaccine Vivotif + Vaccine Dukoral + oats;Biological: Vaccine Vivotif + Vaccine Dukoral;Dietary Supplement: Oats;Other: PlaceboHaukeland University HospitalHelse VestTerminated18 Years80 YearsAll3Phase 2Norway
55ChiCTR-TRC-08000145
2008-09-012008-08-25The study of the treatment and rehabilitation of ulcerative colitisThe study of the treatment and rehabilitation of ulcerative colitis Ulcerative Colitis1:5-ASA and low residue diet;2:5-ASA and EN;3:5-ASA and low residue diet and microecology prepar;4:5-ASA and low residue diet ang Gln;5:5-ASA and EN and Gln and microecology preparation;Friendship Hospital of Capital Medical UniversityNULLCompleted1870Both1:60;2:60;3:60;4:60;5:60;I (Phase 1 study)China
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
56NCT00578799
(ClinicalTrials.gov)
July 200818/12/2007Effects of Probiotics in Patients With Ulcerative ColitisEffects of Probiotics in Patients With Ulcerative Colitis.Ulcerative ColitisDietary Supplement: Kyo-Dophilus;Dietary Supplement: placeboUniversity of California, IrvineWakunaga Pharmaceutical Co., Ltd.Terminated18 Years65 YearsBoth40Phase 1United States
57NCT00621257
(ClinicalTrials.gov)
January 200811/2/2008Vitamin D Levels in Children With IBDOptimization of Vitamin D Stores and Its Impact on the Bone Health and Disease Outcomes of Children and Adolescents With IBD.Inflammatory Bowel Disease;Crohn's Disease;Ulcerative ColitisDietary Supplement: ergocalciferol;Dietary Supplement: CholecalciferolBoston Children’s HospitalNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);Crohn's and Colitis Foundation;NASPGHAN FoundationTerminated5 Years21 YearsAll134N/AUnited States
58NCT02093767
(ClinicalTrials.gov)
August 200719/3/2014Oligofructose-enriched Inulin for the Treatment of Mild to Moderate Active Ulcerative ColitisOpen-Label Trial of a Prebiotic Preparation Containing Inulin and Oligofructose (Synergy-1) for the Treatment of Mild to Moderate Acute Ulcerative ColitisUlcerative ColitisDietary Supplement: Synergy1University of AlbertaCanadian Institutes of Health Research (CIHR);Crohn's and Colitis Canada;Beneo GmbHCompleted18 Years65 YearsAll24N/ACanada
59NCT00403923
(ClinicalTrials.gov)
April 200724/11/2006Amount of Lactose Causing Symptoms in People With Lactose Intolerance and Ulcerative ColitisA Study to Determine the Threshold of Lactose Ingestion That Provokes Symptoms in Lactose Intolerant People Who Also Have Ulcerative ColitisLactose Intolerance;Ulcerative ColitisDietary Supplement: Lactose in waterUniversity Hospitals, LeicesterNULLCompleted18 YearsN/ABoth48United Kingdom
60NCT00951548
(ClinicalTrials.gov)
October 20062/8/2009Food Supplementation With VSL#3 as a Support to Standard Pharmaceutical Therapy in Ulcerative ColitisFood Supplementation With the Probiotic Preparation VSL#3 as a Support to Standard Pharmaceutical Therapy in Patients With Mild to Moderate Active Ulcerative Colitis. A Double-blind, Randomized, Placebo Controlled StudyUlcerative ColitisDietary Supplement: VSL#3;Dietary Supplement: PlaceboVSL PharmaceuticalsNULLCompleted18 YearsN/ABoth144N/AItaly
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
61NCT00145015
(ClinicalTrials.gov)
December 20041/9/2005FishGastro Study: Fish Consumption and Gastro-Intestinal HealthFish Consumption and Gastro-Intestinal Health With Special Emphasis on Reduction of Risk of Colon Cancer and Inflammatory Bowel DiseaseColorectal Cancer;Ulcerative Colitis;PolypsBehavioral: Increased dietary intake of salmon or codInstitute of Food ResearchWageningen University;University of Jena;University of East Anglia;European Commission;Food Standards Agency, United KingdomCompleted18 Years80 YearsBoth270N/ANetherlands;United Kingdom
62EUCTR2004-000611-25-IE
(EUCTR)
19/10/200416/08/2004A Phase 3, Multicenter, Randomized, Double-Blind, Parallel-Arm, 52-Week Dose Comparison Study of the Efficacy and Safety of 25mg QD and 50mg QD of OPC-6535 Oral Tablets and 800 mg BID of Asacol® in the Maintenance of Remission in Subjects with Ulcerative Colitis. - COREA Phase 3, Multicenter, Randomized, Double-Blind, Parallel-Arm, 52-Week Dose Comparison Study of the Efficacy and Safety of 25mg QD and 50mg QD of OPC-6535 Oral Tablets and 800 mg BID of Asacol® in the Maintenance of Remission in Subjects with Ulcerative Colitis. - CORE Maintenance of remission of ulcerative colitisProduct Name: OPC-6535
Product Code: OPC-6535
Other descriptive name: 6-[2-(3,4-diethoxyphenyl)thiazol-4-yl] pyridine-2-carboxylic acid
Trade Name: Asacol (mesalamine) Delayed-release Tablets
Product Name: Asacol
INN or Proposed INN: Mesalamine
Other descriptive name: 5-amino-2-hydroxybenzoic acid
Otsuka Maryland Research Institute, Inc.NULLNot RecruitingFemale: yes
Male: yes
1725Phase 3Hungary;Ireland
63EUCTR2004-000611-25-HU
(EUCTR)
15/10/200421/07/2004A Phase 3, Multicenter, Randomized, Double-Blind, Parallel-Arm, 52-Week Dose Comparison Study of the Efficacy and Safety of 25mg QD and 50mg QD of OPC-6535 Oral Tablets and 800 mg BID of Asacol® in the Maintenance of Remission in Subjects with Ulcerative Colitis. - COREA Phase 3, Multicenter, Randomized, Double-Blind, Parallel-Arm, 52-Week Dose Comparison Study of the Efficacy and Safety of 25mg QD and 50mg QD of OPC-6535 Oral Tablets and 800 mg BID of Asacol® in the Maintenance of Remission in Subjects with Ulcerative Colitis. - CORE Maintenance of remission of ulcerative colitisProduct Name: OPC-6535
Product Code: OPC-6535
Other descriptive name: 6-[2-(3,4-diethoxyphenyl)thiazol-4-yl] pyridine-2-carboxylic acid
Trade Name: Asacol (mesalamine) Delayed-release Tablets
Product Name: Asacol
INN or Proposed INN: Mesalamine
Other descriptive name: 5-amino-2-hydroxybenzoic acid
Otsuka Maryland Research Institute, Inc.NULLNot RecruitingFemale: yes
Male: yes
1725Phase 3Hungary;Ireland
64NCT00259571
(ClinicalTrials.gov)
April 200328/11/2005Retarded Phosphatidylcholine Versus Mesalazin in Remission of Ulcerative Colitis.Prospektive, Randomisierte, Doppelblinde, Mesalazin-kontrollierte (Double-dummy Verfahren) Multizenter-Studie Zur Beurteilung Der Annahme Der äquivalenten Wirkung Von Intestinal Retardiert Freigesetztem Phosphatidylcholin gegenüber Mesalazin (Non-inferiority Study) in Der Remissionserhaltung Der Colitis Ulcerosa.Ulcerative ColitisDrug: retarded release phosphatidylcholineHeidelberg UniversityDietmar Hopp StiftungWithdrawn15 Years80 YearsBoth0Phase 2;Phase 3Germany
65NCT00940576
(ClinicalTrials.gov)
July 200015/7/2009Dietetic Efficacy of Mare's Milk for Patients With Chronic Inflammatory Bowel DiseasesDietetic Effects of Mare's Milk in Patients With Chronic Inflammatory Bowel Diseases (IBD) - a Double Blind Placebo Controlled Cross-over Study.Ulcerative Colitis;Crohns DiseaseDietary Supplement: mare´s milk;Other: placebo drinkUniversity of JenaGerman Federal Ministry of Education and ResearchCompleted10 Years50 YearsAll17N/AGermany