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Alcohol    (DrugBank: Alcohol)

4 diseases
告示番号疾患名（ページ内リンク）臨床試験数
13多発性硬化症／視神経脊髄炎1
58肥大型心筋症2
279巨大静脈奇形（頚部口腔咽頭びまん性病変）1
298遺伝性膵炎5

13. 多発性硬化症／視神経脊髄炎　［臨床試験数：3,050，薬物数：2,147（DrugBank：348），標的遺伝子数：244，標的パスウェイ数：228］
Searched query = "Multiple sclerosis/Neuromyelitis optica", "Multiple sclerosis", "Neuromyelitis optica", "MS", "NMOSD", "Devic disease", "Balo concentric sclerosis", "Baló concentric sclerosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 3,050 trial found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT00220922
(ClinicalTrials.gov)		August 200420/9/2005A Study to Evaluate the Impact on Skin (Injection Site) Reactions of Using Alcohol Wipes Prior to Daily Injections of Copaxone®.An Open-Label, Randomized, Single Cross-Over Study of Isopropyl Alcohol Wipes Versus No Injection Site Preparation on Local Injection Site Reactions Among Persons With Multiple Sclerosis Who Perform Daily Injections of Copaxone®Multiple SclerosisProcedure: Alcohol Wipes vs. No Alcohol WipesTeva Neuroscience, Inc.NULLCompleted18 YearsN/ABoth50Phase 4United States

58. 肥大型心筋症　［臨床試験数：92，薬物数：126（DrugBank：35），標的遺伝子数：40，標的パスウェイ数：141］
Searched query = "Hypertrophic cardiomyopathy"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
2 / 92 trials found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT04133532
(ClinicalTrials.gov)		March 5, 202016/10/2019Effect of Metoprolol in Post Alcohol Septal Ablation Patients With Hypertrophic CardiomyopathyEffect of Metoprolol in Post Alcohol Septal Ablation Patients With Hypertrophic CardiomyopathyHypertrophic CardiomyopathyDrug: MetoprololUniversity Hospital, MotolNULLRecruiting18 Years75 YearsAll50Phase 4Czechia
2NCT00035386
(ClinicalTrials.gov)		April 20022/5/2002Alcohol Septal Ablation in Obstructive Hypertrophic Cardiomyopathy: A Pilot StudyTrans-Right Ventricular Approach to Alcohol Septal Ablation in Obstructive Hypertrophic Cardiomyopathy: A Pilot Feasibility StudyHypertrophic CardiomyopathyProcedure: trans-right ventricular alcohol septal ablation (TRVASA)National Heart, Lung, and Blood Institute (NHLBI)NULLCompletedN/AN/ABoth12Phase 2United States

279. 巨大静脈奇形（頚部口腔咽頭びまん性病変）　［臨床試験数：12，薬物数：23（DrugBank：9），標的遺伝子数：3，標的パスウェイ数：103］
Searched query = "Huge venous malformation with cervical, oral and pharyngeal diffuse lesion", "Huge venous malformation", "Venous malformation"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 12 trial found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1EUCTR2009-011276-29-FR
(EUCTR)		21/08/200915/05/2009Systemic and local diffusion of ethanol after administration of ethanol 96% formulated in a gel (L0122 Gel) and ethanol 98% solution (absolute ethanol) by the percutaneous route, in patients with congenital venous malformations (CVM): pharmacokinetic, pharmacodynamic and clinical study.Systemic and local diffusion of ethanol after administration of ethanol 96% formulated in a gel (L0122 Gel) and ethanol 98% solution (absolute ethanol) by the percutaneous route, in patients with congenital venous malformations (CVM): pharmacokinetic, pharmacodynamic and clinical study. patients with congenital venous malformations (CVM)Product Name: Ethanol gel
Product Code: L0122
Other descriptive name: ETHANOL (96 PER CENT)
Trade Name: Dehydrated Alcohol (Absolute Alcohol) BP for Injection
Product Name: Dehydrated Alcohol (Absolute Alcohol) BP for Injection
Other descriptive name: ETHANOL BP		ORFAGENNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes		24France

298. 遺伝性膵炎　［臨床試験数：93，薬物数：168（DrugBank：51），標的遺伝子数：48，標的パスウェイ数：134］
Searched query = "Hereditary pancreatitis", "Chronic pancreatitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
5 / 93 trials found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT02965898
(ClinicalTrials.gov)		September 201623/9/2016The Effect of Vitamin D Substitution on the Development of Chronic PancreatitisThe Effect of Vitamin D Substitution on Pancreatic Parenchyma and Development of Fibrosis After First Acute Alcoholic Pancreatitis: A Randomized Prospective TrialChronic PancreatitisDietary Supplement: Vitamin D 100ug;Dietary Supplement: Vitamin D 10ugTampere University HospitalOrion Corporation, Orion PharmaRecruiting18 Years101 YearsAll260N/AFinland
2NCT02487225
(ClinicalTrials.gov)		May 201529/6/2015Pentoxifylline Treatment in Acute Pancreatitis (AP)Pentoxifylline Treatment in Acute Pancreatitis: A Double-Blind Placebo - Controlled Randomized TrialAcute Pancreatitis (AP);Gallstone Pancreatitis;Alcoholic Pancreatitis;Trauma Acute Pancreatitis;Hypertriglyceridemia Acute Pancreatitis;Idiopathic (Unknown) Acute Pancreatitis;Medication Induced Acute Pancreatitis;Cancer Acute Pancreatitis;Miscellaneous (i.e. Acute on Chronic Pancreatitis)Drug: Pentoxifylline;Drug: PlaceboMayo ClinicNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Completed18 Years100 YearsAll83Phase 3United States
3NCT04574297
(ClinicalTrials.gov)		January 1, 201127/9/2020An Observational Study on the Natural Course of Chronic PancreatitisThe Impact of Genetic and Environmental Factors on the Progression of Chronic Pancreatitis:An Observational StudyChronic Pancreatitis;Genetic Mutation;Smoking, Tobacco;Drinking, AlcoholBehavioral: smoking and alcohol assumption;Diagnostic Test: genetic sequencingChanghai HospitalNULLActive, not recruitingN/AN/AAll965NULL
4NCT00782795
(ClinicalTrials.gov)		November 200829/10/2008Chronic Pancreatitis. Effect of Pioglitazone on Endocrine Function, Exocrine Function & Structure, Pain & Life QualityPhase II Study of Chronic Pancreatitis and the Effect of Pioglitazone on Endocrine Function, Exocrine Function & Structure, Pain & Life QualityChronic Pancreatitis;Insulin Resistance;Normal or Mildly Abnormal Stool Fat LevelsDrug: Pioglitazone;Drug: PlaceboUniversity of MichiganNational Institute on Alcohol Abuse and Alcoholism (NIAAA);Takeda Pharmaceuticals North America, Inc.Completed18 Years75 YearsAll64Phase 2United States
5NCT00583271
(ClinicalTrials.gov)		June 200220/12/2007A Prospective Study of EUS Guided Celiac BlockA Prospective Study of Endoscopic Ultrasound-guided Celiac (CB) EffectivenessChronic Pancreatitis;Pancreatic CancerDrug: triamcinolone;Drug: 98% dehydrated alcoholIndiana UniversityNULLCompleted18 YearsN/ABoth127N/AUnited States

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