DDrare: Database of Drug Development for Rare Diseases

Dapsone (DrugBank: Dapsone)

5 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
35	天疱瘡	1
42	結節性多発動脈炎	1
60	再生不良性貧血	1
84	サルコイドーシス	1
90	網膜色素変性症	0

35. 天疱瘡　［臨床試験数：87，薬物数：114（DrugBank：37），標的遺伝子数：17，標的パスウェイ数：158］

Searched query = "Pemphigus"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 87 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00429533 (ClinicalTrials.gov)	November 1996	29/1/2007	Efficacy of Dapsone as a Steroid Sparing Agent in Pemphigus Vulgaris	A Prospective Randomized Placebo-Controlled Clinical Trial of Dapsone as a Glucocorticoid-Sparing Agent in Maintenance Phase Pemphigus Vulgaris	Pemphigus Vulgaris	Drug: Dapsone	Jacobus Pharmaceutical	NULL	Terminated	18 Years	80 Years	Both	48	Phase 2	United States

42. 結節性多発動脈炎　［臨床試験数：14，薬物数：27（DrugBank：16），標的遺伝子数：26，標的パスウェイ数：102］

Searched query = "Polyarteritis nodosa", "PAN"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 14 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02939573 (ClinicalTrials.gov)	January 2017	18/10/2016	A Randomized Multicenter Study for Isolated Skin Vasculitis	A Randomized Multicenter Study for Isolated Skin Vasculitis	Primary Cutaneous Vasculitis;Cutaneous Polyarteritis Nodosa;IgA Vasculitis;Henoch-Schönlein Purpura	Drug: Colchicine;Drug: Dapsone;Drug: Azathioprine	University of Pennsylvania	National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS);National Center for Advancing Translational Science (NCATS);Office of Rare Diseases (ORD)	Recruiting	18 Years	N/A	All	90	Phase 2	United States;Canada;Japan

60. 再生不良性貧血　［臨床試験数：218，薬物数：362（DrugBank：81），標的遺伝子数：39，標的パスウェイ数：155］

Searched query = "Aplastic anemia"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 218 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00993694 (ClinicalTrials.gov)	January 2009	9/10/2009	Methemoglobinemia in Young Patients With Hematologic Cancer or Aplastic Anemia Treated With Dapsone	Dapsone Induced Methemoglobinemia in Pediatric Hematologic Malignancy and Aplastic Anemia	Chronic Myeloproliferative Disorders;Leukemia;Lymphoma;Lymphoproliferative Disorder;Methemoglobinemia;Multiple Myeloma and Plasma Cell Neoplasm;Myelodysplastic Syndromes;Myelodysplastic/Myeloproliferative Neoplasms;Nonmalignant Neoplasm	Drug: chemotherapy;Drug: dapsone;Other: medical chart review;Procedure: assessment of therapy complications	Vanderbilt University	National Cancer Institute (NCI)	Completed	N/A	18 Years	All	41	N/A	United States

84. サルコイドーシス　［臨床試験数：143，薬物数：221（DrugBank：79），標的遺伝子数：82，標的パスウェイ数：165］

Searched query = "Sarcoidosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 143 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00000596 (ClinicalTrials.gov)	June 1978	27/10/1999	Diffuse Fibrotic Lung Disease		Lung Diseases;Pulmonary Fibrosis;Sarcoidosis	Drug: prednisone;Drug: cyclophosphamide;Drug: dapsone	National Heart, Lung, and Blood Institute (NHLBI)	NULL	Completed	18 Years	N/A	Both		Phase 2	NULL

90. 網膜色素変性症　［臨床試験数：103，薬物数：158（DrugBank：42），標的遺伝子数：52，標的パスウェイ数：107］

Searched query = "Retinitis pigmentosa", "Rod dystrophy", "Rod-Cone Dystrophy"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 103 trial found