Indocyanine green (DrugBank: Indocyanine green)
7 diseases| 告示番号 | 疾患名（ページ内リンク） | 臨床試験数 |
|---|---|---|
| 46 | 悪性関節リウマチ | 5 |
| 51 | 全身性強皮症 | 1 |
| 96 | クローン病 | 2 |
| 235 | 副甲状腺機能低下症 | 2 |
| 278 | 巨大リンパ管奇形（頚部顔面病変） | 2 |
| 291 | ヒルシュスプルング病（全結腸型又は小腸型） | 1 |
| 296 | 胆道閉鎖症 | 2 |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT04046146 (ClinicalTrials.gov) | December 15, 2019 | 23/7/2019 | Near InfraRed Fluorescence Using Indocyanine Green and Magnetic Resonance Lymphography of Lymphatic Transport | Near InfraRed Fluorescence Using Indocyanine Green and Magnetic Resonance Lymphography of Lymphatic Transport | Rheumatoid Arthritis | Drug: Indocyanine Green;Device: MultiSpectral Imaging System | University of Rochester | NULL | Completed | 18 Years | 89 Years | All | 2 | Phase 1 | United States |
| 2 | NCT02680067 (ClinicalTrials.gov) | December 8, 2015 | 7/12/2015 | NIR Fluorescence Imaging of Lymphatic Transport Using ICG | Near InfraRed Fluorescence Imaging of Lymphatic Transport Using Indocyanine Green | Rheumatoid Arthritis | Drug: Indocyanine Green;Device: MultiSpectral Imaging System | University of Rochester | National Institutes of Health (NIH);National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | Recruiting | 18 Years | 89 Years | All | 30 | Phase 1 | United States |
| 3 | NCT02876874 (ClinicalTrials.gov) | December 2014 | 3/2/2015 | Relationship Between the Activity of Rheumatoid Arthritis and Lymph Node Morphology and Lymphatics Drainage | the Relationship Between the Activity of Rheumatoid Arthritis(RA) and Popliteal/Epitrochlear Lymph Node Morphology and the Drainage of Hand/Foot Superficial Lymphatic Vessels | Rheumatoid Arthritis;Lymph Node Mass;Lymphatic Vessel; Dilatation | Drug: indocyanine green(ICG) | Shanghai University of Traditional Chinese Medicine | NULL | Recruiting | 18 Years | 65 Years | Both | 21 | N/A | China |
| 4 | EUCTR2013-004006-26-DK (EUCTR) | 18/12/2013 | 18/12/2013 | OPAL | Optical images for monitoring treatment changes in rheumatoid arthritis – a longitudinal study with Rheumascan | Detection of synovitis and tenosynovitis in the hands of patients with rheumatoid arthritis; Diagnostic performance of optical imaging in comparison with ultrasound and magnetic resonance imaging. MedDRA version: 16.1;Level: LLT;Classification code 10067132;Term: Synovitis wrist;System Organ Class: 100000004859;Therapeutic area: Diseases [C] - Musculoskeletal Diseases [C05] | Trade Name: ICG-Pulsion INN or Proposed INN: 2-{7-[1,1-dimethyl-3-(4-sulfobutyl)-benz[e]indolin-2-ylidene]-1,3,5-heptatrienyl}-1,1-dimethyl-3-(sulfobutyl)-1H-benz[e]-indolium hydroxide,inner salt Other descriptive name: INDOCYANINE GREEN | Knowledge Centre for Rheumatology and Back Diseases | NULL | Not Recruiting | Female: yes Male: yes | Phase 4 | Denmark | |||
| 5 | JPRN-UMIN000012399 | 2013/10/16 | 26/11/2013 | Performance of Rheumascan in healthy subjects and patients with active rheumatoid arthritis | Rheumatoid arthritis | Patients with active rheumatoid arthritis (1)Assessment of tender and swollen joints by physical examination (2)Joint ultrasonography (assessment of active synovitis by grading and quantification of vascularity using power Doppler or color Doppler ultrasonography) in 22 joints of bilateral hands (3)Gadolinium-enhanced MRI of the hand with more severe arthritis (4)Examination by Rheumascan, a fluorescence optical imaging device using intravenous indocyanine green (ICG) Healthy subjects (1)Assessment of tender and swollen joints by physical examination (2)Joint ultrasonography (assessment of active synovitis by grading and quantification of vascularity using power Doppler or color Doppler ultrasonography) in 22 joints of bilateral hands (3)Examination by Rheumascan, a fluorescence optical imaging device using intravenous indocyanine green (ICG) | Tokyo Medical and Dental University | Diagnostic Imaging Center, Ochanomizu Surugadai Clinic | Complete: follow-up complete | 20years-old | Not applicable | Male and Female | 9 | Not applicable | Japan |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT03155464 (ClinicalTrials.gov) | June 1, 2017 | 24/4/2017 | Intraoperative ICG for Systemic Sclerosis | A Prospective Study of the Utility of Intraoperative, Quantitative Indocyanine Green Angiography in Microvascular Surgery for Systemic Scerlosis | Systemic Sclerosis | Procedure: Order of two elements of surgical procedure;Drug: Indocyanine Green | Duke University | NULL | Withdrawn | 18 Years | N/A | All | 0 | Phase 4 | NULL |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ChiCTR2000035737 | 2020-10-01 | 2020-08-16 | Application of indocyanine green fluorescence angiography in preventing anastomotic recurrence after Crohn’s disease intestinal resection and anastomosis: a single-center, prospective, randomized controlled trial | Application of indocyanine green fluorescence angiography in preventing anastomotic recurrence after Crohn’s disease intestinal resection and anastomosis: a single-center, prospective, randomized controlled trial | Crohn's disease | Experimental group:The scope of surgical resection was determined by indocyanine green fluorescence angiography;Control group:The scope of surgical resection (2cm away from the lesion site) determined by the physician based on experience; | Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine | NULL | Pending | 18 | 70 | Both | Experimental group:45;Control group:45; | China | |
| 2 | ChiCTR-INR-17012532 | 2017-08-23 | 2017-09-01 | The use of indocyanine green fluorescent angiography to guide the surgical treatment of Crohn's disease | The use of indocyanine green fluorescent angiography to guide the surgical treatment of Crohn's disease: a single-center randomized single-blind cohort study | Crohn's disease | Intervention group:Indocyanine green fluorescent angiography;control group:Physiological saline; | Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine | NULL | Recruiting | 18 | 70 | Both | Intervention group:40;control group:40; | China |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | EUCTR2019-003506-26-ES (EUCTR) | 05/03/2020 | 14/01/2020 | Determination of Parathyroid Function by Fluorescence With Indocyanine Green (ICG) After Total Thyroidectomy | Determination of Parathyroid Function by Fluorescence With Indocyanine Green (ICG) After Total Thyroidectomy | Patients undergoing total thyroidectomy with visualization of the parathyroid glands under infrared light after intraoperative intravenous injection of 5 mg of indocyanine green to predict the possible occurrence of postoperative hypocalcemia MedDRA version: 20.1;Level: LLT;Classification code 10020949;Term: Hypocalcemia;System Organ Class: 100000004861 MedDRA version: 20.0;Classification code 10043777;Term: Thyroidectomy total;System Organ Class: 100000004865 MedDRA version: 21.0;Level: PT;Classification code 10080819;Term: Post procedural hypoparathyroidism;System Organ Class: 10022117 - Injury, poisoning and procedural complications;Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Surgical Procedures, Operative [E04] | Trade Name: Verde de Indocianina (Indocyanine Green) Product Name: Indocyanine Green INN or Proposed INN: Indocyanine green Other descriptive name: INDOCYANINE GREEN | Hospital Universitari Son Espases | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 40 | Phase 4 | Spain | ||
| 2 | NCT04012476 (ClinicalTrials.gov) | November 2016 | 28/6/2019 | Determination of Parathyroid Function by Fluorescence With Indocyanine Green (ICG) After Total Thyroidectomy | Determination of Parathyroid Function by Fluorescence With Indocyanine Green (ICG) After Total Thyroidectomy | Hypocalcemia;Total Thyroidectomy;Hypoparathyroidism Postprocedural | Drug: Indocyanine Green | Hospital Son Espases | Universitat de les Illes Balears | Recruiting | 18 Years | N/A | All | 40 | Phase 4 | Spain |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | JPRN-jRCTs041190036 | 03/08/2017 | 04/06/2019 | Visualization of lymphatic malformation | The efficacy of local injection of indocyanine green for visualizing lymphatic malformation | lymphatic malformation | Local injection of indocyanine green | Tainaka Takahisa | NULL | Recruiting | Not applicable | Not applicable | Both | 25 | Phase 2 | Japan |
| 2 | JPRN-UMIN000025845 | 2017/03/01 | 25/01/2017 | The efficacy of local injection of indocyanine green for visualizing lymphatic malformation | lymphatic malformation | Local injection of indocyanine green | Nagoya University Graduate School ofMedicine | NULL | Recruiting | 1years-old | 30years-old | Male and Female | 25 | Not selected | Japan |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT04020939 (ClinicalTrials.gov) | March 16, 2020 | 2/7/2019 | The Role of Indocyanine Green Angiography Fluorescence on Intestinal Resections in Pediatric Surgery. | The Role of Indocyanine Green Angiography Fluorescence on Intestinal Resections in Pediatric Surgery. | Intestinal Atresia;Necrotizing Enterocolitis;Hirschsprung Disease;Gastroschisis;Intestinal Obstruction;Incarcerated Hernia;Intussusception;Malrotation;Volvulus;Meconium Ileus;Intestinal Perforation;Trauma | Device: SPY imaging;Drug: Indocyanine Green | St. Justine's Hospital | NULL | Recruiting | N/A | 16 Years | All | 35 | N/A | Canada |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | JPRN-UMIN000028549 | 2017/08/03 | 05/08/2017 | The efficacy of navigation surgery using indocyanine green for visualizing bile duct | Biliary atresia, Congenital biliary dilation, Cholelithiasis, hepato-biliary-pancreatic tumor | Injection of indocyanine green | Nagoya University Graduate School of Medicine | NULL | Pending | Not applicable | Not applicable | Male and Female | 100 | Not selected | Japan | |
| 2 | JPRN-UMIN000027972 | 2017/01/01 | 01/07/2017 | Assessment of Indocyanine Green excretion using pinpoint endoscopic fluorescence imaging system for diagnosis of biliary atresia; prospective study. | Biliary atresia | To inject the "Indocyanine Green" (0.5mg/kg) within 30 seconds. | Juntendo University School of Medicine | NULL | Complete: follow-up complete | 1months-old | 4months-old | Male and Female | 10 | Phase 2 | Japan |