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Dehydroepiandrosterone    (DrugBank: Dehydroepiandrosterone)

5 diseases
告示番号疾患名（ページ内リンク）臨床試験数
49全身性エリテマトーデス5
53シェーグレン症候群3
83アジソン病1
96クローン病1
113筋ジストロフィー1

49. 全身性エリテマトーデス　［臨床試験数：827，薬物数：638（DrugBank：168），標的遺伝子数：108，標的パスウェイ数：191］
Searched query = "Systemic lupus erythematosus", "SLE"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
5 / 827 trials found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT00189124
(ClinicalTrials.gov)		September 200313/9/2005Dehydroepiandrosterone (DHEA) in Systemic Lupus Erythematosus (SLE) for Coronary Artery Disease (CAD) PreventionDoes DHEA Improve Endothelial Dysfunction and Other Cardiovascular Risk Factors in Premenopausal Women With Systemic Lupus?Systemic Lupus ErythematosusDrug: Dehydroepiandrosterone (DHEA)University of MichiganArthritis FoundationCompleted18 YearsN/AFemale13Phase 2;Phase 3United States
2NCT00391924
(ClinicalTrials.gov)		May 200024/10/2006Dehydroepiandrosterone Administration in Women With Systemic Lupus Erythematosus or Primary Sjögren's SyndromeFatigue and General Well-Being in Patients With Systemic Lupus Erythematosus or Primary Sjögren's Syndrome: Effects of Dehydroepiandrosterone AdministrationLupus Erythematosus, Systemic;Sjogren's SyndromeDrug: DehydroepiandrosteroneUMC UtrechtUniversity Medical Centre Groningen;Dutch Arthritis AssociationCompleted18 YearsN/AFemale120Phase 2Netherlands
3NCT00004662
(ClinicalTrials.gov)		March 199624/2/2000Phase III Randomized, Double-Blind, Placebo-Controlled Study of Dehydroepiandrosterone in Women With Active Systemic Lupus ErythematosusSystemic Lupus ErythematosusDrug: dehydroepiandrosteroneNational Center for Research Resources (NCRR)Northwestern UniversityCompleted18 YearsN/AFemale300Phase 3NULL
4NCT00004665
(ClinicalTrials.gov)		June 199524/2/2000Phase II Study of Long-Term Dehydroepiandrosterone for Systemic Lupus ErythematosusSystemic Lupus ErythematosusDrug: dehydroepiandrosteroneNational Center for Research Resources (NCRR)Northwestern UniversityCompleted18 YearsN/AFemale20Phase 2NULL
5NCT00004795
(ClinicalTrials.gov)		August 199424/2/2000Phase II/III Randomized, Double-Blind, Placebo-Controlled Study of Dehydroepiandrosterone in Women With Mild to Moderate Systemic Lupus ErythematosusSystemic Lupus ErythematosusDrug: dehydroepiandrosteroneNational Center for Research Resources (NCRR)Northwestern UniversityCompleted18 YearsN/AFemale190Phase 2;Phase 3NULL

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53. シェーグレン症候群　［臨床試験数：234，薬物数：270（DrugBank：85），標的遺伝子数：49，標的パスウェイ数：174］
Searched query = "Sjogren syndrome", "Sjögren syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
3 / 234 trials found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT00543166
(ClinicalTrials.gov)		February 20039/10/2007Sex Steroids in Sjögren's Syndrome: Effect of Substitution Treatment on FatigueSex Steroids in Sjögren's Syndrome: Effect of Substitution Treatment on FatigueSjogren's SyndromeDrug: dehydroepiandrosteroneHelsinki UniversityGöteborg University;Uppsala UniversityActive, not recruiting18 Years80 YearsBoth107Phase 4Finland
2NCT00391924
(ClinicalTrials.gov)		May 200024/10/2006Dehydroepiandrosterone Administration in Women With Systemic Lupus Erythematosus or Primary Sjögren's SyndromeFatigue and General Well-Being in Patients With Systemic Lupus Erythematosus or Primary Sjögren's Syndrome: Effects of Dehydroepiandrosterone AdministrationLupus Erythematosus, Systemic;Sjogren's SyndromeDrug: DehydroepiandrosteroneUMC UtrechtUniversity Medical Centre Groningen;Dutch Arthritis AssociationCompleted18 YearsN/AFemale120Phase 2Netherlands
3NCT00001598
(ClinicalTrials.gov)		May 19973/11/1999DHEA Treatment for Sjogren's SyndromeDehydroepiandrosterone (DHEA) Treatment for Sjogren's SyndromeLacrimal Apparatus Disease;Salivary Gland Disease;Sjogren's Syndrome;XerostomiaDrug: DehydroepiandrosteroneNational Institute of Dental and Craniofacial Research (NIDCR)NULLCompletedN/AN/AFemale28Phase 2United States

83. アジソン病　［臨床試験数：20，薬物数：42（DrugBank：13），標的遺伝子数：6，標的パスウェイ数：17］
Searched query = "Addison disease", "Primary chronic adrenocortical insufficiency", "Autoimmune polyglandular syndrome", "Hypoparathyroidism-Addison-Monilia syndrome", "HAM syndrome", "Schmidt syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 20 trial found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT00004313
(ClinicalTrials.gov)		August 199518/10/1999Phase III Randomized, Double-Blind, Placebo-Controlled Study of Dehydroepiandrosterone Replacement for Primary Adrenal InsufficiencyAddison's DiseaseDrug: dehydroepiandrosteroneNational Center for Research Resources (NCRR)University of California, Los AngelesCompleted18 YearsN/ABoth40Phase 3NULL

96. クローン病　［臨床試験数：2,209，薬物数：1,276（DrugBank：240），標的遺伝子数：166，標的パスウェイ数：210］
Searched query = "Crohn disease", "Terminal ileitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 2,209 trial found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT00106314
(ClinicalTrials.gov)		January 200522/3/2005An Efficacy and Safety Evaluation of Inflabloc Cap in the Treatment of Patients With Crohn's DiseaseA Randomized, Double-Blind, Multi-Center, Dose Response, Efficacy and Safety Evaluation of Inflabloc Cap in the Treatment of Patients With Moderately Active Crohn's DiseaseCrohn's DiseaseDrug: Dehydroepiandrosterone [DHEA]Inflabloc PharmaceuticalsNULLCompleted18 YearsN/ABoth75Phase 2United States;Canada

113. 筋ジストロフィー　［臨床試験数：567，薬物数：442（DrugBank：93），標的遺伝子数：55，標的パスウェイ数：151］
Searched query = "Muscular dystrophy", "Dystrophinopathies", "Myotilinopathy", "Laminopathy", "Caveolinopathy", "LGMD1C", "Desminopathy", "Sarcoglycanopathy", "α-dystroglycanopathy", "FCMD", "Walker-Warburg syndrome", "Muscle-eye-brain disease", "Myotonic dystrophy", "Integrin α7 deficient CMD", "Rigid spine syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 567 trial found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT00167609
(ClinicalTrials.gov)		November 200410/9/2005Efficacy and Safety of DHEA for Myotonic DystrophyPhase 3 Study of Oral Dehydroepiandrosterone (DHEA) in Adults With Myotonic DystrophyMyotonic DystrophyDrug: dehydroepiandrosterone 100 and 400 mgUniversity of VersaillesAssociation Française contre les Myopathies (AFM), Paris;AP-HPCompleted18 Years70 YearsBoth75Phase 2;Phase 3France

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