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Sevoflurane    (DrugBank: Sevoflurane)

6 diseases
告示番号疾患名（ページ内リンク）臨床試験数
6パーキンソン病1
21ミトコンドリア病2
22もやもや病1
34神経線維腫症1
98好酸球性消化管疾患1
296胆道閉鎖症3

6. パーキンソン病　［臨床試験数：2,123，薬物数：2,046（DrugBank：324），標的遺伝子数：183，標的パスウェイ数：198］
Searched query = "Parkinson disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 2,123 trial found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1ChiCTR1900026956
2019-10-212019-10-27Minimum alveolar concentration-awake of sevoflurane in patients with Parkinson's diseaseMinimum alveolar concentration-awake of sevoflurane in patients with Parkinson's disease Parkinson’s diseaseParkinson’s disease group:Sevoflurane induction;Non-Parkinson’s disease group:Sevoflurane induction;The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of ChinaNULLPending4064BothParkinson’s disease group:30;Non-Parkinson’s disease group:30;N/AChina

21. ミトコンドリア病　［臨床試験数：23，薬物数：29（DrugBank：28），標的遺伝子数：44，標的パスウェイ数：65］
Searched query = "Mitochondrial disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
2 / 23 trials found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT02053766
(ClinicalTrials.gov)		January 10, 201431/1/2014Anesthesia in Patients With Mitochondrial DiseaseAnesthesia in Patients With Mitochondrial DiseaseMitochondrial DiseasesDrug: Sevoflurane;Drug: Dexmedetomidine;Drug: PropofolThe University of Texas Health Science Center, HoustonNULLRecruitingN/A17 YearsAll60N/AUnited States
2NCT01001585
(ClinicalTrials.gov)		September 200621/10/2009Anesthetic Effects in Mitochondrial DiseaseAnesthetic Effects in Mitochondrial DiseaseMitochondrial DiseaseDrug: sevofluraned sesslerNULLTerminated12 Months16 YearsBoth55N/AUnited States

22. もやもや病　［臨床試験数：11，薬物数：18（DrugBank：11），標的遺伝子数：28，標的パスウェイ数：43］
Searched query = "Moyamoya disease", "Occlusive disease in circle of Willis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 11 trial found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT02510586
(ClinicalTrials.gov)		August 201524/7/2015Sevoflurane and Hyperperfusion SyndromeEffect of Sevoflurane-induced Postconditioning on the Incidence of Postoperative Cerebral Hyperperfusion Syndrome After Revascularization Surgery in Adult Patients With Moyamoya DiseaseHyperperfusion Syndrome;Moyamoya DiseaseDrug: SevofluraneSeoul National University HospitalNULLNot yet recruiting18 YearsN/ABoth152N/ANULL

34. 神経線維腫症　［臨床試験数：120，薬物数：182（DrugBank：72），標的遺伝子数：84，標的パスウェイ数：194］
Searched query = "Neurofibromatosis", "NF1", "von Recklinghausen disease", "NF2"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 120 trial found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT03513757
(ClinicalTrials.gov)		March 4, 20184/2/2018Dexmedetomidine and Propofol for Pediatric MRI SedationAn Observer-blinded Randomized Study of Propofol Infusion vs Bolus Dexmedetomidine and Propofol Sedation for Pediatric Magnetic Resonance ImagingHeadache;Tumor;Seizure Disorder;Neurofibromatoses;Hydrocephalus;Abdominal Neoplasm;Spine DeformityDrug: propofol;Drug: Dexmedetomidine;Drug: Glycopyrrolate;Drug: Lidocaine 1% Injectable Solution;Drug: Nitrous Oxide;Drug: SevofluraneMedical College of WisconsinNULLCompleted12 Months60 MonthsAll40Phase 4United States

98. 好酸球性消化管疾患　［臨床試験数：128，薬物数：147（DrugBank：40），標的遺伝子数：34，標的パスウェイ数：132］
Searched query = "Eosinophilic gastrointestinal disease", "Eosinophilic gastroenteritis", "Eosinophilic esophagitis", "Eosinophilic colitis", "Eosinophilic gastro-intestinal disorder", "EGID", "Neonatal food-protein induced enterocolitis", "N-FPIES"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 128 trial found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT02038894
(ClinicalTrials.gov)		December 20091/5/2013Comparing Anesthetic Techniques in Children Having EsophagogastroduodenoscopiesComparison Of Different Anesthetic Techniques In Children Undergoing EsophagogastroduodenoscopiesEosinophilic EsophagitisDrug: Intubated with Sevoflurane (IS);Drug: Intubated with Propofol (IP);Drug: Zofran - no intubation;Drug: PropofolChildren's Hospital Medical Center, CincinnatiNULLCompleted1 Year12 YearsAll179N/AUnited States

296. 胆道閉鎖症　［臨床試験数：53，薬物数：56（DrugBank：31），標的遺伝子数：43，標的パスウェイ数：50］
Searched query = "Biliary atresia"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
3 / 53 trials found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1ChiCTR-IOR-17013585
2018-06-142017-11-24Comparison of renal injury in children with liver transplantation under combined anesthesia with sevoflurane and propofolThe influence of sevoflurane and propofol on acute kidney injury in pediatric living donor liver transplantion Congenital biliary atresiaP:Propofol compound anesthesia;Se:Sevoflurane compound anesthesia;Tianjin First Central HospitalNULLRecruiting0.52BothP:60;Se:60;China
2NCT02471209
(ClinicalTrials.gov)		January 20123/6/2015Biliary Atresia, Hepatic Buffer Response and SevofluraneBiliary AtresiaDrug: SevofluraneChildren's Hospital of Fudan UniversityNULLCompleted1 Month3 MonthsBoth25N/ANULL
3NCT01443572
(ClinicalTrials.gov)		September 201116/9/2011The Comparison of Desflurane and Sevoflurane on Postoperative Recovery and Hepatic Function of Biliary Atresia Patients During Kasai OperationKasai Operation;Biliary AtresiaDrug: desflurane anesthetics;Drug: sevoflurane anestheticsYonsei UniversityNULLCompletedN/A1 YearBoth40N/AKorea, Republic of

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