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Acipimox    (DrugBank: Acipimox)

2 diseases
告示番号疾患名（ページ内リンク）臨床試験数
78下垂体前葉機能低下症2
265脂肪萎縮症1

78. 下垂体前葉機能低下症　［臨床試験数：462，薬物数：346（DrugBank：45），標的遺伝子数：41，標的パスウェイ数：80］
Searched query = "Hypopituitarism", "Anterior pituitary hypothyroidism", "Syndrome of abnormal secretion of gonadotropin", "Hyposecretion of gonadotropins", "Adrenocorticotropic hormone deficiency", "ACTH deficiency", "Thyroid-stimulating hormone deficiency", "TSH deficiency", "Growth hormone deficiency", "GH deficiency", "GHD", "CGHD", "AGHD", "Prolactin deficiency", "PRL deficiency"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
2 / 462 trials found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT02782208
(ClinicalTrials.gov)		February 10, 201618/5/2016Lipolytic Effects of GH in Hypopituitary Patients in VivoLipolytic Effects of GH in Hypopituitary Patients in Vivo: Molecular Mechanisms and Temporal Patterns.Hypopituitarism;Insulin Resistance;Endocrine System Diseases;Glucose Metabolism Disorders;Metabolic Diseases;Pituitary Diseases;Brain DiseasesDrug: Acipimox;Drug: Placebo;Drug: GH substitution;Other: GH pauseUniversity of AarhusNULLCompleted18 Years70 YearsMale9N/ADenmark
2NCT01209416
(ClinicalTrials.gov)		June 201224/9/2010The Effect of Pharmacological Antilipolysis on the Metabolic Effects of GhrelinThe Effect of Pharmacological Antilipolysis on the Metabolic Effects of GhrelinMetabolism;Insulin Resistance;HypopituitarismDrug: Acipimox;Drug: Ghrelin;Other: PlaceboUniversity of AarhusNULLCompleted18 Years65 YearsMale8N/ADenmark

265. 脂肪萎縮症　［臨床試験数：109，薬物数：164（DrugBank：59），標的遺伝子数：26，標的パスウェイ数：94］
Searched query = "Lipodystrophy", "Berardinelli-Seip syndrome", "Lawrence syndrome", "Barraquer-Simons syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 109 trial found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT00246402
(ClinicalTrials.gov)		September 200227/10/2005Acipimox to Improve Hyperlipidemia and Insulin Sensitivity Associated With HIVAnti-Lipolytic Strategy for HIV LipodystrophyInsulin Resistance;Cardiovascular Diseases;Heart Diseases;HIV Infections;Hypertriglyceridemia;HyperlipidemiaDrug: AcipimoxNational Heart, Lung, and Blood Institute (NHLBI)NULLCompleted18 Years65 YearsBoth30N/AUnited States