DDrare: Database of Drug Development for Rare Diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
86	肺動脈性肺高血圧症	1

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02746237 (ClinicalTrials.gov)	November 2015	18/3/2016	Single and Multiple Ascending Doses Clinical Pharmacology Study With KAR5585	A Randomized, Double-blind, Placebo-controlled, Phase 1, First-in-human, Single-center, Safety, Tolerability, Ventricular Repolarization and Pharmacokinetic Study of Single and Multiple Ascending Doses of KAR5585 in Healthy Subjects	Pulmonary Arterial Hypertension	Drug: KAR5585 Capsules;Drug: Placebo Capsules	Karos Pharmaceuticals	NULL	Completed	18 Years	65 Years	Both	120	Phase 1	United States

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

NCT02746237
(ClinicalTrials.gov)

November 2015

18/3/2016

Single and Multiple Ascending Doses Clinical Pharmacology Study With KAR5585

A Randomized, Double-blind, Placebo-controlled, Phase 1, First-in-human, Single-center, Safety, Tolerability, Ventricular Repolarization and Pharmacokinetic Study of Single and Multiple Ascending Doses of KAR5585 in Healthy Subjects

Pulmonary Arterial Hypertension

Drug: KAR5585 Capsules;Drug: Placebo Capsules

Karos Pharmaceuticals

NULL

Completed

18 Years

65 Years

Both

120

Phase 1

United States