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Epx-100 (clemizole hydrochloride)    (DrugBank: Clemizole)

1 disease
IDDisease name (Link within this page)Number of trials
140Dorabe syndrome2

140. Dorabe syndrome    [ 83 clinical trials,   54 drugs,   (DrugBank: 13 drugs),   48 drug target genes,   62 drug target pathways]
Searched query = "Dorabe syndrome", "Dravet syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
2 / 83 trials found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT04462770
(ClinicalTrials.gov)		September 20206/7/2020A Trial of EPX-100 (Clemizole Hydrochloride) as an Add-on Therapy in Children With Dravet SyndromeA 20-Week Multicenter, Randomized, Double-Blind, Placebo- Controlled, Proof of Concept Trial of EPX-100 (Clemizole Hydrochloride) as Adjunctive Therapy in Children With Dravet SyndromeDravet SyndromeDrug: EPX-100 (Clemizole HCl);Drug: PlaceboEpygenixGreenLight Clinical PTY LTDRecruiting2 Years17 YearsAll24Phase 2United States
2NCT04069689
(ClinicalTrials.gov)		August 29, 201922/8/2019Study of Safety and Pharmacokinetics of Oral Doses of EPX-100 in Healthy Subjects.A Phase I, Placebo-Controlled, Double-Blind, 2-Period Study to Assess Safety and Pharmacokinetics of Escalating Single and Multiple Oral Doses of EPX-100 in Fasting Healthy Subjects and Following a High-Fat MealDravet SyndromeDrug: EPX-100 (Clemizole Hydrochloride);Drug: PlacebosEpygenixNULLCompleted18 Years50 YearsAll24Phase 1United States