Mk0653, ezetimibe    (DrugBank: Ezetimibe)

1 disease
IDDisease name (Link within this page)Number of trials
260Sitosterolemia3

260. Sitosterolemia    [ 13 clinical trials,   13 drugs,   (DrugBank: 4 drugs),   1 drug target gene,   1 drug target pathway]
Searched query = "Sitosterolemia"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
3 / 13 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT00092898
(ClinicalTrials.gov)
October 200423/9/2004An Investigational Drug Study to Lower Non-Cholesterol Sterol Levels Associated With Sitosterolemia (0653-062)(COMPLETED)A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Efficacy and Safety of Adding Ezetimibe 30 mg to An Ongoing Regimen of Ezetimibe 10 mg in Patients Homozygous SitosterolemiaLipid Metabolism, Inborn Errors;Heart DiseaseDrug: MK0653, ezetimibe;Drug: Comparator: placeboMerck Sharp & Dohme Corp.NULLCompleted18 Years85 YearsAll30Phase 3United States
2NCT00092820
(ClinicalTrials.gov)
February 12, 200123/9/2004Sitosterolemia Extension Study (0653-004)(COMPLETED)A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of MK0653 When Added to Current Regimen in Patients With Homozygous SitosterolemiaLipid Metabolism, Inborn Errors;Heart DiseaseDrug: MK0653, ezetimibe;Drug: Comparator: placeboMerck Sharp & Dohme Corp.NULLCompleted10 YearsN/AAll58Phase 3NULL
3NCT00092807
(ClinicalTrials.gov)
February 12, 200123/9/2004Sitosterolemia Extension Study (0653-003)(COMPLETED)A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of MK0653 When Added to Current Regimen in Patients With Homozygous Sitosterolemia - 1 Year Open-Label ExtensionLipid Metabolism, Inborn Errors;Heart DiseaseDrug: MK0653, ezetimibe;Drug: Comparator: placeboMerck Sharp & Dohme Corp.NULLCompleted10 YearsN/AAll37Phase 3United States