Cftr modulators (DrugBank: -)
1 disease| ID | Disease name (Link within this page) | Number of trials |
|---|---|---|
| 299 | Cystic fibrosis | 6 |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT04580368 (ClinicalTrials.gov) | January 4, 2021 | 2/10/2020 | Testing Drug Efficacy in Cystic Fibrosis Through N-of-1 Trials | Testing Drug Efficacy in Cystic Fibrosis Through N-of-1 Trials | Cystic Fibrosis | Drug: CFTR Modulators | Children's Hospital Medical Center, Cincinnati | NULL | Not yet recruiting | 6 Years | N/A | All | 50 | N/A | NULL |
| 2 | NCT04415268 (ClinicalTrials.gov) | June 9, 2020 | 28/5/2020 | Combined Effect of CFTR Protein Modulator Drugs and Exercise in Cystic Fibrosis | Combined Effect of CFTR Protein Modulator Drugs and Exercise on Pulmonary Function, Fitness, Sweat Test and Quality of Life in Children With Cystic Fibrosis | Cystic Fibrosis in Children | Behavioral: Exercise;Behavioral: Unsupervised exercise;Drug: CFTR Modulators | Universidad Europea de Madrid | NULL | Recruiting | 6 Years | 18 Years | All | 11 | N/A | Spain |
| 3 | NCT04301856 (ClinicalTrials.gov) | January 1, 2020 | 21/2/2020 | Response to CFTR Modulators in CF Patients Under 18 Years | Evaluation of the Response to CFTR Modulators in Patients With Cystic Fibrosis Less Than 18 Years of Age | Cystic Fibrosis in Children | Drug: CFTR Modulators | Societe Francaise de la Mucoviscidose | NULL | Recruiting | N/A | 18 Years | All | 600 | France | |
| 4 | NCT04206436 (ClinicalTrials.gov) | December 18, 2019 | 18/12/2019 | CFTR Modulator Effects on Bone and Muscle in Adults With Cystic Fibrosis | CFTR Modulator Effects on Bone and Muscle in Adults With Cystic Fibrosis | Cystic Fibrosis;Bone Loss;Muscle Loss | Drug: Cftr Modulators | Indiana University | Cystic Fibrosis Foundation | Enrolling by invitation | 18 Years | N/A | All | 60 | United States | |
| 5 | NCT03506061 (ClinicalTrials.gov) | September 4, 2019 | 13/4/2018 | Trikafta in Cystic Fibrosis Patients | iPS Cell Response to CFTR Modulators: Study of Trikafta in CF Patients Carrying Partial Function Mutations | Cystic Fibrosis | Drug: Trikafta | Emory University | National Heart, Lung, and Blood Institute (NHLBI) | Recruiting | 12 Years | N/A | All | 22 | Phase 2 | United States |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
| 6 | NCT01348204 (ClinicalTrials.gov) | March 2010 | 1/6/2010 | Nasal Potential Studies Utilizing Cystic Fibrosis Transmembrane Regulator (CFTR) Modulators | Nasal Potential Studies Utilizing CFTR Modulators (UAB Center for Clinical and Translational Science) | Cystic Fibrosis | Other: quercetin | University of Alabama at Birmingham | National Institutes of Health (NIH) | Completed | 8 Years | 65 Years | Both | 32 | Phase 2 | United States |