DDrare: Database of Drug Development for Rare Diseases

Broccoli (DrugBank: Broccoli)

3 diseases

ID	Disease name (Link within this page)	Number of trials
36	Epidermolysis bullosa	1
97	Ulcerative colitis	1
299	Cystic fibrosis	1

36. Epidermolysis bullosa [ 147 clinical trials, 170 drugs, (DrugBank: 40 drugs), 32 drug target genes, 113 drug target pathways]

Searched query = "Epidermolysis bullosa", "EBS", "JEB", "DDEB", "RDEB", "Kindler syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 147 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02592954 (ClinicalTrials.gov)	September 2015	29/10/2015	Effect of Broccoli Sprout Extract on Keratinocyte Differentiation in Normal Skin	Effect of Broccoli Sprout Extract on Keratinocyte Differentiation in Normal Skin	Epidermolysis Bullosa Simplex;Pachyonychia Congenita	Drug: Jojoba oil with broccoli sprout extract;Drug: Jojoba oil (placebo)	Johns Hopkins University	NULL	Completed	18 Years	N/A	All	5	Phase 1	United States

97. Ulcerative colitis [ 2,269 clinical trials, 1,331 drugs, (DrugBank: 241 drugs), 114 drug target genes, 181 drug target pathways]

Searched query = "Ulcerative colitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 2,269 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-UMIN000041972	2020/10/01	01/10/2020	Clinical trial on the effects of dietary intake of sulforaphane-rich broccoli sprouts on severity of ulcerative colitis.	Clinical trial on the effects of dietary intake of sulforaphane-rich broccoli sprouts on severity of ulcerative colitis. - BS-UC-2020	ulcerative colitis	Broccoli Sprouts (20 g/day, 8 weeks) Alfalfa Sprouts (20 g/day, 8 weeks)	University of Tsukuba	NULL	Recruiting	20years-old	Not applicable	Male and Female	50	Not selected	Japan

299. Cystic fibrosis [ 1,592 clinical trials, 1,539 drugs, (DrugBank: 255 drugs), 81 drug target genes, 162 drug target pathways]

Searched query = "Cystic fibrosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 1,592 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01315665 (ClinicalTrials.gov)	April 2011	14/3/2011	Effect of Sulforaphane in Broccoli Sprouts on Nrf2 Activation	Evaluation of the Effect of Sulforaphane in Broccoli Sprouts on Nrf2 Activation, Measures of Oxidative Stress, and Neutrophil Migration to Mucosal Surfaces in Healthy and CF Subjects	Cystic Fibrosis	Dietary Supplement: Broccoli sprouts	University Hospitals Cleveland Medical Center	Cystic Fibrosis Foundation	Completed	18 Years	49 Years	All	15	N/A	United States