Clonidine (DrugBank: Clonidine)
2 diseases| ID | Disease name (Link within this page) | Number of trials |
|---|---|---|
| 6 | Parkinson disease | 4 |
| 78 | Hypopituitarism | 4 |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT03552068 (ClinicalTrials.gov) | May 15, 2019 | 17/5/2018 | Study of Clonidine Efficacy for the Treatment of Impulse Control Disorders in Parkinson's Disease: | Study of Clonidine Efficacy for the Treatment of Impulse Control Disorders in Parkinson's Disease: A Pilot Double Blind Randomized Trial | Parkinson's Disease;Mpulse Control Disorders | Drug: placebo;Drug: Clonidine | Hospices Civils de Lyon | NULL | Recruiting | 30 Years | 80 Years | All | 38 | Phase 2 | France |
| 2 | NCT01796483 (ClinicalTrials.gov) | October 2012 | 13/2/2013 | EEG and Pharmacological Exploration of Executive Dysfunctions Induced by STN-DBS in PD | Exploration électroencéphalographie et Pharmacologique Des Dysfonctionnements exécutifs Induits Par la Stimulation cérébrale Profonde du Noyau Sous-thalamique Dans la Maladie de Parkinson | Parkinson Disease | Device: Clonidine (Catapressan);Device: Placebo 90 minutes before EEG | Hospices Civils de Lyon | NULL | Completed | 40 Years | 70 Years | All | 37 | N/A | France |
| 3 | NCT01370811 (ClinicalTrials.gov) | August 2011 | 8/6/2011 | A Relative Efficacy and Safety Study of OC Oral Solution for Sialorrhoea in Patients With Parkinson's Disease | A Phase II, Double-blind, Randomized, Placebo-controlled 4-way Crossover Study to Evaluate the Relative Efficacy and Safety of OC Oral Solution (Oxybutynin and Clonidine) for Sialorrhoea in Patients With Parkinson's Disease | Sialorrhoea | Drug: OC oral solution treatment A;Drug: OC oral solution treatment B;Drug: OC oral solution treatment C;Drug: OC oral solution treatment D | Orient Pharma Co., Ltd. | NULL | Completed | 40 Years | 80 Years | Both | 24 | Phase 2 | United States |
| 4 | EUCTR2007-004654-81-GB (EUCTR) | 20/12/2007 | 16/10/2007 | A phase IIa study to evaluate the relative efficacy and safety/tolerability of a single agent vs. a combination treatment for reducing saliva secretion in Parkinson’s disease patients | A phase IIa study to evaluate the relative efficacy and safety/tolerability of a single agent vs. a combination treatment for reducing saliva secretion in Parkinson’s disease patients | Sialorrhoea associated with Parkinson's Disease MedDRA version: 9.1;Level: LLT;Classification code 10059812;Term: Sialorrhoea | Trade Name: Catapres ampoules INN or Proposed INN: Clonidine hydrochloride Trade Name: Ditropan elixir INN or Proposed INN: Oxybutynin hydrochloride | Summit (Cambridge) Ltd. | NULL | Not Recruiting | Female: yes Male: yes | Phase 2a | United Kingdom |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT04465565 (ClinicalTrials.gov) | December 2020 | 3/7/2020 | Fluids Administration During Combined Clonidine-Arginine Growth Hormone Stimulation Test | Fluids Administration During Combined Clonidine-Arginine Growth Hormone Stimulation Test- Randomized, 2 Arms, Controlled Study | Growth Hormone Deficiency | Procedure: 9% Sodium Chloride (NaCl) IV | Rabin Medical Center | NULL | Not yet recruiting | 7 Years | 16 Years | All | 120 | N/A | Israel |
| 2 | EUCTR2006-003678-82-NL (EUCTR) | 10/07/2007 | 02/04/2008 | Pharmacokinetics and effects of oral clonidine in children with suspected Growth Hormone deficiency | Pharmacokinetics and effects of oral clonidine in children with suspected Growth Hormone deficiency | Clonidine is studied in the paediatric population, more specific children with short stature. It is used as a diagnostic tool to establish Growth Hormone reserve in routine practice. MedDRA version: 8.1;Level: LLT;Classification code 10005573;Term: Blood growth hormone decreased | Trade Name: Catapresan | Centre for Human Drug Research | NULL | Not Recruiting | Female: yes Male: yes | Netherlands | ||||
| 3 | NCT00134420 (ClinicalTrials.gov) | February 2001 | 22/8/2005 | Growth Hormone and Chromosome 18q- and Abnormal Growth | Growth Hormone Trial for Children With 18q- and Abnormal Growth | Loss of Chromosome 18q;Growth Hormone Deficiency | Drug: Nutropin AQ;Procedure: Arginine and Clonidine Stimulation Testing;Procedure: Growth Factors Laboratory Testing;Procedure: Neuropsychological Testing | The University of Texas Health Science Center at San Antonio | South Texas Veterans Health Care System;Genentech, Inc. | Completed | N/A | 18 Years | Both | 20 | Phase 3 | United States |
| 4 | EUCTR2010-018781-23-NL (EUCTR) | 17/02/2010 | Diagnose of GH-deficiency: comparing the dietary-protein test with conventional Growth Hormone Stimulation Tests | Diagnose of GH-deficiency: comparing the dietary-protein test with conventional Growth Hormone Stimulation Tests | To investigate if there is a correlation between the peak GH concentrations after ingestion of gelatin protein and the peak GH concentrations after the two standard tests (GHST) in order to discriminate growth hormone deficiency (GHD) and non-GHD. To investigate the differences in coefficient of variation between the different tests (arginine, clonidine, protein). To investigate the frequency of side effects in the different tests (arginine, clonidine, protein). MedDRA version: 12.1;Level: LLT;Classification code 10056438;Term: Growth hormone deficiency | Product Name: Gelatin Product Code: 3 Product Name: Arginin Product Code: 1 Trade Name: Clonidine HCl CF 0,150 mg, tabletten Product Name: Clonidine Product Code: 2 INN or Proposed INN: Clonidin Other descriptive name: CLONIDINE HYDROCHLORIDE | Top Institute Food and Nutrition | NULL | NA | Female: yes Male: yes | Netherlands |