DDrare: Database of Drug Development for Rare Diseases

Other: standard of care sildenafil (DrugBank: Sildenafil)

2 diseases

ID	Disease name (Link within this page)	Number of trials
90	Retinitis pigmentosa	1
301	Macular dystrophy	1

90. Retinitis pigmentosa [ 103 clinical trials, 158 drugs, (DrugBank: 42 drugs), 52 drug target genes, 107 drug target pathways]

Searched query = "Retinitis pigmentosa", "Rod dystrophy", "Rod-Cone Dystrophy"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 103 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04356716 (ClinicalTrials.gov)	November 11, 2014	20/4/2020	Sildenafil for Treatment of Choroidal Ischemia	Sildenafil for Treatment of Choroidal Ischemia	Choroidal Ischemia;Vitelliform Macular Dystrophy;Age-related Macular Degeneration;Central Serous Retinopathy;Retinitis Pigmentosa	Drug: Sildenafil;Other: Standard of Care Sildenafil;Diagnostic Test: Ocular Coherence Tomography-Angiography (OCT-A);Other: Visual Acuity (VA)	Columbia University	NULL	Recruiting	18 Years	N/A	All	25	Phase 2	United States

301. Macular dystrophy [ 41 clinical trials, 47 drugs, (DrugBank: 12 drugs), 12 drug target genes, 66 drug target pathways]

Searched query = "Macular dystrophy", "Best disease", "Stargardt disease", "Cone dystrophy", "Cone rod dystrophy", "X-linked juvenile retinoschisis", "Central areolar choroidal dystrophy"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 41 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04356716 (ClinicalTrials.gov)	November 11, 2014	20/4/2020	Sildenafil for Treatment of Choroidal Ischemia	Sildenafil for Treatment of Choroidal Ischemia	Choroidal Ischemia;Vitelliform Macular Dystrophy;Age-related Macular Degeneration;Central Serous Retinopathy;Retinitis Pigmentosa	Drug: Sildenafil;Other: Standard of Care Sildenafil;Diagnostic Test: Ocular Coherence Tomography-Angiography (OCT-A);Other: Visual Acuity (VA)	Columbia University	NULL	Recruiting	18 Years	N/A	All	25	Phase 2	United States