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123 / 12,170 descriptions found* Show info (disease name, etc.) on mouse-over.
 No.   Drug (Description in trials)   DrugBank   KEGG DRUG  KEGG GENES
 [Number of genes] 
 KEGG PATHWAY 
 [Number of pathways] 
 Disease ID
 [Number of diseases] 
 1   124i-labeled monoclonal antibody mu 11-1f4   -   -   -   -   [1]
28 
 2   124i-p5+14 injection   -   -   -   -   [1]
28 
 3   2-(3,5-dichloro-phenyl)-benzoxazole-6-carboxylate   -   -   -   -   [1]
28 
 4   4'-iodo-4'-deoxydoxorubicin   Iodine   D00108   -   -   [1]
28 
 5   [d-glucitol, 1-deoxy-1-(methylamino)-, 2-(3,5-dichlorophenyl)-6-benzoxazolecarboxylate (1:1)]   Sorbitol   D00096   -   -   [1]
28 
 6   Acyclovir   Acyclovir   D00222   -   -   [2]
13,
28 
 7   Alkeran   Melphalan   D00369   -   -   [2]
28,
60 
 8   Amifostine   Amifostine   D00226   -   -   [1]
28 
 9   Amifostine trihydrate   Amifostine   D00226   -   -   [1]
28 
 10   Amiodarone   Amiodarone   D00636, D02910   [15] ADRA1A, ADRA1B, ADRA1D, ADRB1, KCNJ11, KCNJ12, KCNJ3, KCNJ5, KCNJ8, KCNQ1, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A   [30] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy (DCM), Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Insulin secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway   [2]
28,
127 
 11   Aprotinin   Aprotinin   D02971   -   -   [1]
28 
 12   Bendamustine   Bendamustine   D07085, D07501   -   -   [2]
28,
61 
 13   Bortezomib   Bortezomib   D03150   [1] PSMB5   [1] Proteasome   [13]
11,
26,
28,
46,
49,
51,
61,
63,
66,
228,
256,
288,
331 
 14   Bortezomib/dexamethasone (bd), followed by autologous stc & maintenance bortezomib/dexamethasone   Dexamethasone   D00292, D00975, D01510, D01615, D01632, D01948, D02174, D02591, D02592   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [1]
28 
 15   Busulfan   Busulfan   D00248   -   -   [13]
19,
20,
28,
36,
49,
51,
60,
65,
164,
274,
284,
285,
326 
 16   Carboplatin   Carboplatin   D01363   -   -   [4]
28,
34,
60,
85 
 17   Carfilzomib   Carfilzomib   D08880   [1] PSMB5   [1] Proteasome   [1]
28 
 18   Carmustine   Carmustine   D00254   -   -   [5]
11,
13,
14,
28,
60 
 19   Cc-5013   Lenalidomide   D04687   [1] TNF   [61] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Dilated cardiomyopathy (DCM), Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pathogenic Escherichia coli infection, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [2]
28,
96 
 20   Chemotherapy   -   -   -   -   [3]
28,
60,
285 
 21   Chimeric fibril-reactive monoclonal anti-body 11-1f4   -   -   -   -   [1]
28 
 22   Chx a-dtpa anti-cd66 antibody   Pentetic acid   D05422   -   -   [1]
28 
 23   Chx-a-dtpa-anti-cd66   Pentetic acid   D05422   -   -   [1]
28 
 24   Cisplatin   Cisplatin   D00275   -   -   [1]
28 
 25   Cphc (carboxy pyrrolidine hexanoyl pyrrolidone carboxylate)   -   -   -   -   [1]
28 
 26   Cyclophosphamide   Cyclophosphamide   D00287, D07760   -   -   [43]
13,
14,
16,
19,
20,
26,
28,
35,
36,
40,
41,
42,
43,
44,
45,
46,
49,
50,
51,
52,
56,
60,
61,
62,
65,
66,
84,
85,
93,
96,
162,
164,
172,
222,
224,
265,
274,
283,
284,
285,
288,
326,
331 
 27   Cyclophosphamide, bortezomib, dexamethasone   Cyclophosphamide   D00287, D07760   -   -   [1]
28 
 28   Cyclophosphamide, bortezomib, dexamethasone plus daratumumab   Cyclophosphamide   D00287, D07760   -   -   [1]
28 
 29   Cyclosporine   Ciclosporin   D00184   [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   [30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway   [33]
11,
14,
19,
20,
28,
36,
40,
41,
42,
45,
46,
49,
50,
53,
56,
58,
60,
62,
64,
65,
90,
95,
97,
162,
164,
222,
226,
228,
234,
283,
284,
285,
302 
 30   D-glucitol   Sorbitol   D00096   -   -   [2]
28,
299 
 31   Daratumumab   Daratumumab   D10777   [1] CD38   [7] Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion   [2]
28,
222 
 32   Daratumumab co-formulated with recombinant human hyaluronidase (rhuph20)   Hyaluronidase   D04455, D04456, D06604   -   -   [1]
28 
 33   Deaxamethasone   -   -   -   -   [1]
28 
 34   Dexamethasone   Dexamethasone   D00292, D00975, D01510, D01615, D01632, D01948, D02174, D02591, D02592   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [20]
13,
16,
28,
35,
46,
53,
63,
65,
70,
74,
75,
81,
83,
84,
90,
96,
97,
222,
296,
299 
 35   Dexamethasone, 40 mg   Dexamethasone   D00292, D00975, D01510, D01615, D01632, D01948, D02174, D02591, D02592   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [1]
28 
 36   Dezamizumab   Dezamizumab   D11471   -   -   [1]
28 
 37   Diflunisal   Diflunisal   D00130   [1] PTGS2   [20] Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway   [1]
28 
 38   Diuretics (plus antiarrhythmic drugs, i.e. amiodarone, in case of complex ventricular arrhithmias)   Amiodarone   D00636, D02910   [15] ADRA1A, ADRA1B, ADRA1D, ADRB1, KCNJ11, KCNJ12, KCNJ3, KCNJ5, KCNJ8, KCNQ1, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A   [30] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy (DCM), Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Insulin secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway   [1]
28 
 39   Diuretics (plus antiarrhythmic drugs, i.e. amiodarone, in case of complex ventricular arrhythmias) plus egcg   Amiodarone   D00636, D02910   [15] ADRA1A, ADRA1B, ADRA1D, ADRB1, KCNJ11, KCNJ12, KCNJ3, KCNJ5, KCNJ8, KCNQ1, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A   [30] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy (DCM), Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Insulin secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway   [1]
28 
 40   Donor lymphocytes   -   -   -   -   [1]
28 
 41   Doxorubicin   Doxorubicin   D03899   [2] TOP2A, TOP2B   [1] Platinum drug resistance   [5]
26,
28,
34,
61,
331 
 42   Doxycycline   Doxycycline   D00307, D02129, D03903, D03904, D07876   -   -   [15]
13,
23,
28,
46,
84,
85,
89,
96,
97,
158,
162,
167,
227,
280,
299 
 43   Dtpa   Pentetic acid   D05422   -   -   [3]
13,
28,
299 
 44   Egcg   Epigallocatechin gallate   -   -   -   [8]
6,
13,
17,
28,
85,
113,
206,
299 
 45   Elotuzumab   Elotuzumab   D09337   -   -   [1]
28 
 46   Enbrel   Etanercept   D00742   [2] LTA, TNF   [61] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Dilated cardiomyopathy (DCM), Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pathogenic Escherichia coli infection, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [3]
28,
46,
271 
 47   Endoxan   -   -   -   -   [2]
13,
28 
 48   Epigallocatechin   Epigallocatechin   -   -   -   [4]
13,
28,
85,
113 
 49   Epigallocatechin-3-gallate (egcg)   Epigallocatechin   -   -   -   [2]
28,
85 
 50   Etoposide   Etoposide   D00125, D04107   [2] TOP2A, TOP2B   [1] Platinum drug resistance   [11]
11,
13,
14,
26,
28,
34,
60,
65,
85,
164,
331 
 51   Filgrastim   Filgrastim   D03235   [1] CSF3R   [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer   [25]
2,
6,
13,
25,
26,
28,
34,
35,
40,
41,
42,
45,
46,
49,
51,
60,
62,
65,
96,
113,
164,
283,
284,
285,
331 
 52   Fludarabine   Fludarabine   D01907, D07966   [1] RRM1   [5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism   [17]
13,
28,
36,
46,
49,
51,
60,
61,
62,
65,
85,
96,
164,
283,
284,
285,
326 
 53   Fludarabine phosphate   Fludarabine   D01907, D07966   [1] RRM1   [5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism   [11]
28,
36,
49,
51,
60,
62,
65,
96,
283,
284,
285 
 54   Fortecortin   -   -   -   -   [1]
28 
 55   Foscarnet   Foscarnet   D00579, D02267   -   -   [2]
28,
60 
 56   Foscarnet sodium   Foscarnet   D00579, D02267   -   -   [2]
28,
60 
 57   Fx-1006a   -   -   -   -   [1]
28 
 58   Ganciclovir   Ganciclovir   D00333, D04301   -   -   [3]
28,
60,
97 
 59   Green tea   Green tea leaf   D06903   -   -   [5]
6,
17,
28,
46,
96 
 60   Green tea extract   Green tea leaf   D06903   -   -   [1]
28 
 61   Gsk2315698   -   -   -   -   [1]
28 
 62   Gsk2398852   -   -   -   -   [1]
28 
 63   Gsk3039294   -   -   -   -   [1]
28 
 64   Human transthyretin antisense oligonucleotide   -   -   -   -   [1]
28 
 65   Humanized igg1, kappa anti-serum amyloid a and anti-al amyloid antibody   -   -   -   -   [1]
28 
 66   Humax-cd38   -   -   -   -   [1]
28 
 67   Hyaluronidase   Hyaluronidase   D04455, D04456, D06604   -   -   [3]
28,
65,
331 
 68   Ibrutinib   Ibrutinib   D10223   [1] BTK   [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency   [2]
28,
61 
 69   Imatinib   Imatinib   D01441, D08066   [3] ABL1, KIT, PDGFRA   [32] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Shigellosis, Viral myocarditis   [11]
13,
28,
34,
35,
46,
51,
85,
86,
87,
89,
162 
 70   Imatinib mesylate   Imatinib   D01441, D08066   [3] ABL1, KIT, PDGFRA   [32] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Shigellosis, Viral myocarditis   [5]
13,
28,
34,
51,
86 
 71   Indium   Indium   -   -   -   [3]
28,
84,
299 
 72   Indium 111-radiolabelled anti-cd66   Indium   -   -   -   [1]
28 
 73   Indium­ 111 ­labelled anti­-cd66   Indium   -   -   -   [1]
28 
 74   Inotersen   Inotersen   D10940   [1] TTR   [1] Thyroid hormone synthesis   [1]
28 
 75   Interferon alfa   Interferon alfa   D03305   [2] IFNAR1, IFNAR2   [17] Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway   [5]
25,
26,
28,
56,
96 
 76   Iodo   Iodine   D00108   -   -   [1]
28 
 77   Ionis-ttr rx   -   -   -   -   [1]
28 
 78   Isatuximab   Isatuximab   D11050   -   -   [1]
28 
 79   Isis 420915   -   -   -   -   [1]
28 
 80   Isis 420915/gsk 299872   -   -   -   -   [1]
28 
 81   Ixazomib   Ixazomib   D10130   [1] PSMB5   [1] Proteasome   [3]
13,
16,
28 
 82   Jnj 54767414   -   -   -   -   [1]
28 
 83   L01aa03   -   -   -   -   [1]
28 
 84   Lenalidomide   Lenalidomide   D04687   [1] TNF   [61] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Dilated cardiomyopathy (DCM), Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pathogenic Escherichia coli infection, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [7]
16,
26,
28,
34,
49,
284,
300 
 85   Lenalidomide, dexamethasone and cyclophosphamide   Cyclophosphamide   D00287, D07760   -   -   [1]
28 
 86   Melflufen   -   -   -   -   [1]
28 
 87   Melphalan   Melphalan   D00369   -   -   [14]
11,
13,
14,
19,
20,
28,
60,
62,
65,
96,
164,
234,
284,
285 
 88   Melphalan, thalidomide and dexamethasone   Dexamethasone   D00292, D00975, D01510, D01615, D01632, D01948, D02174, D02591, D02592   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [1]
28 
 89   Miridesap   Miridesap   D11464   -   -   [1]
28 
 90   Mycophenolate   Mycophenolic acid   D05096   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [33]
2,
11,
13,
14,
19,
20,
28,
35,
36,
42,
43,
45,
49,
51,
53,
60,
62,
65,
66,
84,
85,
95,
96,
162,
164,
222,
224,
226,
234,
283,
284,
285,
300 
 91   Mycophenolate mofetil   Mycophenolate mofetil   D00752, D05094, D05095   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [32]
2,
11,
13,
14,
19,
20,
28,
35,
36,
42,
43,
45,
49,
51,
53,
60,
62,
65,
66,
85,
95,
96,
162,
164,
222,
224,
226,
234,
283,
284,
285,
300 
 92   N-methyl d-(2,3,4,5,6-pentahydroxy-hexyl)-ammonium   -   -   -   -   [1]
28 
 93   Neod001   -   -   -   -   [1]
28 
 94   Neupogen   Filgrastim   D03235   [1] CSF3R   [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer   [4]
13,
28,
51,
285 
 95   Null   -   -   -   -   [17]
6,
13,
14,
15,
28,
37,
46,
49,
51,
63,
86,
90,
96,
97,
107,
145,
271 
 96   Phosphate   Phosphate ion   -   -   -   [29]
2,
3,
11,
12,
13,
28,
36,
46,
49,
51,
53,
60,
62,
65,
70,
78,
81,
83,
90,
96,
97,
164,
235,
256,
283,
284,
285,
286,
299 
 97   Pomalidomide   Pomalidomide   D08976   [2] IL6, TNF   [76] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy (DCM), EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pertussis, Prion diseases, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [6]
28,
34,
51,
85,
227,
331 
 98   Pomalidomide and dexamethasone   Dexamethasone   D00292, D00975, D01510, D01615, D01632, D01948, D02174, D02591, D02592   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [1]
28 
 99   Propylene glycol   Propylene glycol   D00078   -   -   [1]
28 
 100   Propylene glycol-free melphalan hydrochloride   Propylene glycol   D00078   -   -   [1]
28 
 101   Recombinant human hyaluronidase   Hyaluronidase   D04455, D04456, D06604   -   -   [2]
28,
65 
 102   Recombinant interferon alfa   Interferon alfa   D03305   [2] IFNAR1, IFNAR2   [17] Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway   [2]
26,
28 
 103   Revlimid   Lenalidomide   D04687   [1] TNF   [61] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Dilated cardiomyopathy (DCM), Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pathogenic Escherichia coli infection, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [1]
28 
 104   Sargramostim   Sargramostim   D05803   [1] CSF2RA   [4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer   [6]
6,
28,
60,
62,
96,
229 
 105   Siltuximab   Siltuximab   D09669   [1] IL6   [46] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Malaria, Measles, NOD-like receptor signaling pathway, Non-alcoholic fatty liver disease (NAFLD), PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pertussis, Prion diseases, Rheumatoid arthritis, Salmonella infection, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection   [2]
28,
331 
 106   Single infusion of 124i-labeled anti-amyloid mab 11-1f4: 2 mci (1 mg)   -   -   -   -   [1]
28 
 107   Standard of care therapy   -   -   -   -   [1]
28 
 108   Sunitinib   Sunitinib   D06402, D08552   [9] CSF1, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB, RET   [36] Acute myeloid leukemia, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Glioma, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, TNF signaling pathway, Thyroid cancer, Transcriptional misregulation in cancer, VEGF signaling pathway, Viral protein interaction with cytokine and cytokine receptor   [2]
28,
34 
 109   Sunitinib malate   Sunitinib   D06402, D08552   [9] CSF1, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB, RET   [36] Acute myeloid leukemia, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Glioma, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, TNF signaling pathway, Thyroid cancer, Transcriptional misregulation in cancer, VEGF signaling pathway, Viral protein interaction with cytokine and cytokine receptor   [1]
28 
 110   Tafamidis   Tafamidis   D09673   [1] TTR   [1] Thyroid hormone synthesis   [1]
28 
 111   Tafamidis meglumine   Tafamidis   D09673   [1] TTR   [1] Thyroid hormone synthesis   [1]
28 
 112   Tasmar   Tolcapone   D00786   [1] COMT   [4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism   [2]
6,
28 
 113   Tea extract   Green tea leaf   D06903   -   -   [1]
28 
 114   Thalidomide   Thalidomide   D00754   [1] TNF   [61] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Dilated cardiomyopathy (DCM), Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pathogenic Escherichia coli infection, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [18]
2,
16,
20,
28,
49,
51,
53,
65,
84,
85,
94,
96,
97,
227,
271,
280,
298,
331 
 115   Thiotepa   Thiotepa   D00583   -   -   [11]
13,
19,
20,
28,
51,
60,
65,
85,
96,
164,
284 
 116   Tolcapone   Tolcapone   D00786   [1] COMT   [4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism   [3]
6,
28,
127 
 117   Valganciclovir   Valganciclovir   D02495   -   -   [6]
28,
60,
85,
97,
299,
331 
 118   Velcade   Bortezomib   D03150   [1] PSMB5   [1] Proteasome   [1]
28 
 119   Velcade*1fl 3,5mg   Bortezomib   D03150   [1] PSMB5   [1] Proteasome   [1]
28 
 120   Venetoclax   Venetoclax   D10679   [1] BCL2   [39] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Amyotrophic lateral sclerosis (ALS), Apoptosis, Apoptosis - multiple species, Autophagy - animal, Cholinergic synapse, Colorectal cancer, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Epstein-Barr virus infection, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, Gastric cancer, HIF-1 signaling pathway, Hedgehog signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human immunodeficiency virus 1 infection, JAK-STAT signaling pathway, Measles, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Platinum drug resistance, Prostate cancer, Protein processing in endoplasmic reticulum, Shigellosis, Small cell lung cancer, Sphingolipid signaling pathway, Toxoplasmosis, Tuberculosis, p53 signaling pathway   [1]
28 
 121   Yttrium-90   Yttrium y-90   -   -   -   [1]
28 
 122   Yttrium-90 radiolabelled anti-cd66 antibody   Yttrium y-90   -   -   -   [1]
28 
 123   Yttrium­90 radiolabelled anti­cd66   Yttrium y-90   -   -   -   [1]
28 

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