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   e.g. "Sirolimus", "Adalimumab"

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256 / 12,170 descriptions found* Show info (disease name, etc.) on mouse-over.
 No.   Drug (Description in trials)   DrugBank   KEGG DRUG *   KEGG GENES * 
 [Number of genes] 		  KEGG PATHWAY 
 [Number of pathways] 		  Disease ID * 
 [Number of diseases] 
 1   (18)f-fdg   -   -   -   -   [1]
85 
 2   534-1508   -   -   -   -   [1]
85 
 3   68ga-bmv101   -   -   -   -   [1]
85 
 4   [18f]-fba-a20fmdv2   -   -   -   -   [1]
85 
 5   [18f]fp-r01-mg-f2   -   -   -   -   [1]
85 
 6   [68ga]cbp8   -   -   -   -   [1]
85 
 7   Acetate   Acetate   -   -   -   [40]
1,
2,
6,
10,
13,
35,
40,
46,
49,
51,
60,
64,
70,
71,
73,
75,
76,
78,
81,
83,
85,
86,
88,
90,
96,
97,
113,
145,
156,
162,
171,
206,
222,
224,
225,
235,
265,
288,
298,
299 
 8   Acetylcysteine   Acetylcysteine   D00221   -   -   [14]
6,
13,
19,
20,
49,
51,
58,
85,
94,
111,
164,
233,
298,
299 
 9   Act-064992   -   -   -   -   [4]
85,
86,
88,
210 
 10   Act-064992 (macitentan)   Macitentan   D10135   [2] EDNRA, EDNRB   [9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [1]
85 
 11   Adult human mesenchymal stem cells   Remestemcel-l   D09719   -   -   [2]
85,
96 
 12   Aerosol interferon-gamma   -   -   -   -   [1]
85 
 13   Alemtuzumab   Alemtuzumab   D02802   -   -   [13]
13,
15,
19,
20,
46,
51,
60,
63,
65,
85,
96,
164,
284 
 14   Allogeneic adult human mesenchymal stem cells (hmscs)   Remestemcel-l   D09719   -   -   [1]
85 
 15   Ambrisentan   Ambrisentan   D07077   [1] EDNRA   [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [6]
51,
84,
85,
86,
88,
211 
 16   Antimicrobial therapy: co-trimoxazole or doxycycline   Doxycycline   D00307, D02129, D03903, D03904, D07876   -   -   [1]
85 
 17   Art-123   -   -   -   -   [1]
85 
 18   Atezolizumab   Atezolizumab   D10773   [1] CD274   [2] Cell adhesion molecules (CAMs), PD-L1 expression and PD-1 checkpoint pathway in cancer   [1]
85 
 19   Autoantibody reductive therapy   -   -   -   -   [1]
85 
 20   Autologous adipose derived mscs (admscs)   -   -   -   -   [1]
85 
 21   Autologous mesenchymal stem cells derived from bone marrow   -   -   -   -   [1]
85 
 22   Autologous stromal vascular fraction (svf)   -   -   -   -   [1]
85 
 23   Aviptadil   Aviptadil   -   -   -   [4]
49,
51,
85,
86 
 24   Aviptadil, 66 microgram/ml   Aviptadil   -   -   -   [1]
85 
 25   Azapred   -   -   -   -   [1]
85 
 26   Azathioprine   Azathioprine   D00238, D03033   -   -   [18]
11,
13,
19,
35,
42,
43,
44,
45,
46,
49,
65,
66,
85,
94,
95,
96,
97,
162 
 27   Azathioprine/prednisone   Azathioprine   D00238, D03033   -   -   [1]
85 
 28   Azithromycin   Azithromycin   D02134, D06390, D07486   -   -   [6]
13,
84,
85,
96,
228,
299 
 29   Bardoxolone   Bardoxolone   D09584   -   -   [7]
66,
67,
84,
85,
86,
218,
222 
 30   Bardoxolone methyl   Bardoxolone methyl   D09585   -   -   [7]
66,
67,
84,
85,
86,
218,
222 
 31   Bbt-877, multiple doses   -   -   -   -   [1]
85 
 32   Bbt-877, single dose   -   -   -   -   [1]
85 
 33   Bevacizumab   Bevacizumab   D06409   [1] VEGFA   [21] AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway   [9]
13,
34,
85,
86,
87,
89,
227,
280,
331 
 34   Bg00011   -   -   -   -   [1]
85 
 35   Bi 1015550   -   -   -   -   [1]
85 
 36   Bibf 1120   -   -   -   -   [2]
51,
85 
 37   Blood sample collection   -   -   -   -   [1]
85 
 38   Bms-986020   -   -   -   -   [2]
51,
85 
 39   Bms-986278   -   -   -   -   [1]
85 
 40   Bone marrow mesenchymal stem cells   -   -   -   -   [1]
85 
 41   Bosentan   Bosentan   D01227, D07538   [2] EDNRA, EDNRB   [9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [9]
13,
41,
47,
51,
84,
85,
86,
88,
210 
 42   Carbon   Activated charcoal   D03251   -   -   [7]
6,
46,
85,
86,
96,
97,
298 
 43   Carbon monoxide   Carbon monoxide   D09706   -   -   [3]
85,
86,
298 
 44   Carboplatin   Carboplatin   D01363   -   -   [4]
28,
34,
60,
85 
 45   Cbdca   Carboplatin   D01363   -   -   [1]
85 
 46   Cc-90001   -   -   -   -   [1]
85 
 47   Cc-930   -   -   -   -   [1]
85 
 48   Cd3/cd19 negative hematopoietic stem cells   -   -   -   -   [1]
85 
 49   Cnto 888 1 mg/kg   -   -   -   -   [1]
85 
 50   Cnto 888 15 mg/kg   -   -   -   -   [1]
85 
 51   Cnto 888 5 mg/kg   -   -   -   -   [1]
85 
 52   Cnto888   -   -   -   -   [1]
85 
 53   Co-trimoxazole   -   -   -   -   [1]
85 
 54   Combined plasma exchange (pex), rituximab, and corticosteroids   Rituximab   D02994   [1] MS4A1   [1] Hematopoietic cell lineage   [1]
85 
 55   Corticosteroid (prednisolone)   Prednisolone   D00472, D00980, D00981, D00982, D01239, D01998, D02156, D03301   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [1]
85 
 56   Cotrimoxazole   -   -   -   -   [2]
85,
97 
 57   Cromoglycate   Cromoglicic acid   D00526, D07753   -   -   [1]
85 
 58   Cromolyn   Cromoglicic acid   D00526, D07753   -   -   [2]
85,
98 
 59   Cromolyn sodium   Cromoglicic acid   D00526, D07753   -   -   [1]
85 
 60   Cyclophosphamide   Cyclophosphamide   D00287, D07760   -   -   [43]
13,
14,
16,
19,
20,
26,
28,
35,
36,
40,
41,
42,
43,
44,
45,
46,
49,
50,
51,
52,
56,
60,
61,
62,
65,
66,
84,
85,
93,
96,
162,
164,
172,
222,
224,
265,
274,
283,
284,
285,
288,
326,
331 
 61   Cysteine   L-cysteine   D00026, D02326   -   -   [9]
6,
13,
19,
84,
85,
88,
90,
254,
296 
 62   Dabigatran   Dabigatran   D09707   [1] F2   [7] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton   [2]
85,
91 
 63   Dasatinib   Dasatinib   D03658, D06414   [8] ABL1, EPHA2, FYN, KIT, LCK, PDGFRB, SRC, YES1   [73] Acute myeloid leukemia, Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, Glioma, GnRH signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Mitophagy - animal, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Primary immunodeficiency, Prion diseases, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Sphingolipid signaling pathway, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection   [1]
85 
 64   Dasatinib + quercetin   Dasatinib, Quercetin   D03658, D06414   [8] ABL1, EPHA2, FYN, KIT, LCK, PDGFRB, SRC, YES1   [73] Acute myeloid leukemia, Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, Glioma, GnRH signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Mitophagy - animal, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Primary immunodeficiency, Prion diseases, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Sphingolipid signaling pathway, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection   [1]
85 
 65   Disodium cromoglycate (dscg)   Cromoglicic acid   D00526, D07753   -   -   [1]
85 
 66   Disodium cromoglycate [cromolyn sodium]   Cromoglicic acid   D00526, D07753   -   -   [1]
85 
 67   Doxycycline   Doxycycline   D00307, D02129, D03903, D03904, D07876   -   -   [15]
13,
23,
28,
46,
84,
85,
89,
96,
97,
158,
162,
167,
227,
280,
299 
 68   Egcg   Epigallocatechin gallate   -   -   -   [8]
6,
13,
17,
28,
85,
113,
206,
299 
 69   Endobronchial infusion of adult mesenchymal stem cells   -   -   -   -   [1]
85 
 70   Epigallocatechin   Epigallocatechin   -   -   -   [4]
13,
28,
85,
113 
 71   Epigallocatechin-3-gallate (egcg)   Epigallocatechin   -   -   -   [2]
28,
85 
 72   Esbriet   Pirfenidone   D01583   [6] CCL2, IL10, IL1A, IL1B, IL6, TNF   [80] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease (American trypanosomiasis), Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy (DCM), EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pertussis, Prion diseases, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [3]
51,
85,
228 
 73   Esbriet® (pirfenidon)   Pirfenidone   D01583   [6] CCL2, IL10, IL1A, IL1B, IL6, TNF   [80] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease (American trypanosomiasis), Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy (DCM), EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pertussis, Prion diseases, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [1]
85 
 74   Etanercept   Etanercept   D00742   [2] LTA, TNF   [61] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Dilated cardiomyopathy (DCM), Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pathogenic Escherichia coli infection, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [14]
15,
35,
38,
39,
46,
50,
53,
56,
60,
85,
228,
271,
285,
298 
 75   Etoposide   Etoposide   D00125, D04107   [2] TOP2A, TOP2B   [1] Platinum drug resistance   [11]
11,
13,
14,
26,
28,
34,
60,
65,
85,
164,
331 
 76   Ez-2053   -   -   -   -   [2]
85,
299 
 77   Ez-2053 5mg/kg   -   -   -   -   [2]
85,
299 
 78   Fentanyl   Fentanyl   D00320, D01399   [1] OPRM1   [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction   [5]
46,
70,
85,
215,
231 
 79   Fentanyl citrate   Fentanyl   D00320, D01399   [1] OPRM1   [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction   [1]
85 
 80   Fg-3019   -   -   -   -   [2]
85,
222 
 81   Fg-3019 10mg/ml in 10 ml vials   -   -   -   -   [1]
85 
 82   Fludarabine   Fludarabine   D01907, D07966   [1] RRM1   [5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism   [17]
13,
28,
36,
46,
49,
51,
60,
61,
62,
65,
85,
96,
164,
283,
284,
285,
326 
 83   Fluimucil® 600 mg effervescent tablets   -   -   -   -   [1]
85 
 84   Fluorine (18f) fludeoxyglucose   -   -   -   -   [2]
84,
85 
 85   Fostair   -   -   -   -   [1]
85 
 86   G-csf   Filgrastim   D03235   [1] CSF3R   [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer   [12]
6,
13,
16,
49,
51,
60,
65,
85,
96,
284,
285,
331 
 87   G321605   -   -   -   -   [3]
85,
96,
97 
 88   G451990   -   -   -   -   [1]
85 
 89   Gallium68-dota-noc   -   -   -   -   [1]
85 
 90   Gbt440   -   -   -   -   [1]
85 
 91   Gc1008   Fresolimumab   D09620   [3] TGFB1, TGFB2, TGFB3   [34] AGE-RAGE signaling pathway in diabetic complications, Amoebiasis, Cell cycle, Cellular senescence, Chagas disease (American trypanosomiasis), Chronic myeloid leukemia, Colorectal cancer, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy (DCM), FoxO signaling pathway, Gastric cancer, Hepatitis B, Hepatocellular carcinoma, Hippo signaling pathway, Human T-cell leukemia virus 1 infection, Hypertrophic cardiomyopathy (HCM), Inflammatory bowel disease (IBD), Intestinal immune network for IgA production, Leishmaniasis, MAPK signaling pathway, Malaria, MicroRNAs in cancer, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, TGF-beta signaling pathway, Th17 cell differentiation, Toxoplasmosis, Tuberculosis   [2]
85,
222 
 92   Gefapixant   Gefapixant   D11349   [1] P2RX3   [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Taste transduction   [2]
85,
226 
 93   Gefapixant first,   Gefapixant   D11349   [1] P2RX3   [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Taste transduction   [1]
85 
 94   Gkt137831   -   -   -   -   [2]
85,
93 
 95   Glpg1205   Glpg1205   -   -   -   [3]
85,
96,
97 
 96   Glpg1690   -   -   -   -   [2]
51,
85 
 97   Granulocyte colony stimulating factor   Filgrastim   D03235   [1] CSF3R   [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer   [3]
2,
36,
85 
 98   Gs-6624   Simtuzumab   -   -   -   [1]
85 
 99   Gsk2126458   -   -   -   -   [1]
85 
 100   Gsk3008348   -   -   -   -   [1]
85 
 101   Gsk3008348 nebuliser solution   -   -   -   -   [1]
85 
 102   Hec 68498   -   -   -   -   [1]
85 
 103   Hec585   -   -   -   -   [1]
85 
 104   High dose bibf 1120 twice daily   -   -   -   -   [1]
85 
 105   Humanized anti-alpha v beta 6 mab   -   -   -   -   [1]
85 
 106   Hydroxyurea   Hydroxyurea   D00341   [1] RRM2   [6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway   [8]
3,
13,
19,
20,
65,
85,
86,
284 
 107   Hyperoxia   -   -   -   -   [1]
85 
 108   Hyperpolarized 129 xenon gas comparing idiopathic pulmonary fibrosis (ipf) treatment   Xenon   D01901, D06339   -   -   [1]
85 
 109   Hyperpolarized 129-xenon gas   Xenon   D01901, D06339   -   -   [1]
85 
 110   Idl-2965 oral capsule   -   -   -   -   [1]
85 
 111   Iloprost   Iloprost   D02721   [1] PTGIR   [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction   [4]
51,
84,
85,
86 
 112   Iloprost inhalation solution (ventavis)   Iloprost   D02721   [1] PTGIR   [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction   [2]
85,
86 
 113   Imatinib   Imatinib   D01441, D08066   [3] ABL1, KIT, PDGFRA   [32] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Shigellosis, Viral myocarditis   [11]
13,
28,
34,
35,
46,
51,
85,
86,
87,
89,
162 
 114   Imatinib mesylate (gleevec)   Imatinib   D01441, D08066   [3] ABL1, KIT, PDGFRA   [32] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Shigellosis, Viral myocarditis   [1]
85 
 115   Immukin   -   -   -   -   [1]
85 
 116   Inhaled carbon monoxide   Carbon monoxide   D09706   -   -   [1]
85 
 117   Inhaled nitric oxide   Nitric oxide   D00074   -   -   [2]
85,
86 
 118   Inhaled nitric oxide - 30 mcg/kg ibw/hr   Nitric oxide   D00074   -   -   [1]
85 
 119   Inhaled nitric oxide 5,10,15 mcg/kg ibw/hr   Nitric oxide   D00074   -   -   [1]
85 
 120   Inhaled nitric oxide 75 mcg/kg ibw/hr   Nitric oxide   D00074   -   -   [2]
85,
86 
 121   Inhaled td139   Td139   -   -   -   [1]
85 
 122   Inomax 400ppm mol/mol inhalation gas   Nitric oxide   D00074   -   -   [2]
85,
299 
 123   Interferon alpha oral lozenge   -   -   -   -   [1]
85 
 124   Interferon gamma-1b   -   -   -   -   [7]
65,
85,
90,
228,
299,
301,
326 
 125   Interferon gamma-1b (actimmune)   Interferon gamma-1b   D00747   [2] IFNGR1, IFNGR2   [19] Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease (IBD), Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Salmonella infection, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis   [1]
85 
 126   Interferon-alpha lozenges   -   -   -   -   [1]
85 
 127   Interferon-gamma 1b   -   -   -   -   [1]
85 
 128   Intermediate dose bibf 1120 twice daily   -   -   -   -   [1]
85 
 129   Intravenous immunoglobulin   Immune globulin human   -   -   -   [16]
2,
11,
14,
17,
18,
35,
38,
39,
49,
51,
63,
65,
85,
164,
296,
309 
 130   Ivig   Immune globulin human   -   -   -   [12]
11,
13,
14,
17,
18,
50,
51,
63,
65,
85,
164,
296 
 131   Iw001   -   -   -   -   [1]
85 
 132   Kd025   -   -   -   -   [2]
51,
85 
 133   L - antineoplastic and immunomodulating agents   -   -   -   -   [1]
85 
 134   L01 - antineoplastic agents   -   -   -   -   [1]
85 
 135   L01x - other antineoplastic agents   -   -   -   -   [1]
85 
 136   L01xe - protein kinase inhibitors   -   -   -   -   [1]
85 
 137   L01xe31 - nintedanib   Nintedanib   D10481   [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB   [34] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway   [1]
85 
 138   Lanreotide   Lanreotide   D04666   -   -   [4]
67,
73,
85,
298 
 139   Lanreotide acetate   Lanreotide   D04666   -   -   [3]
73,
85,
298 
 140   Lebrikizumab   Lebrikizumab   D09633   [1] IL13   [8] Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease (IBD), JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation   [1]
85 
 141   Letairis   Ambrisentan   D07077   [1] EDNRA   [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [1]
85 
 142   Letairis 10 mg   Ambrisentan   D07077   [1] EDNRA   [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [1]
85 
 143   Letairis 5 mg   Ambrisentan   D07077   [1] EDNRA   [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [1]
85 
 144   Losartan   Losartan   D00357, D08146   [1] AGTR1   [14] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [18]
13,
17,
19,
46,
58,
66,
67,
85,
96,
97,
98,
113,
164,
167,
179,
215,
222,
299 
 145   Low dose bibf 1120 twice daily   -   -   -   -   [1]
85 
 146   Low dose bibf1120 once daily   -   -   -   -   [1]
85 
 147   Lung stem cells   -   -   -   -   [1]
85 
 148   Macitentan   Macitentan   D10135   [2] EDNRA, EDNRB   [9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [5]
51,
85,
86,
88,
210 
 149   Medical air   Medical air   -   -   -   [3]
85,
86,
193 
 150   Medical air (sham o2)   Medical air   -   -   -   [1]
85 
 151   Mg-s-2525   -   -   -   -   [1]
85 
 152   Minocycline   Minocycline   D00850, D05045   -   -   [13]
2,
6,
8,
13,
46,
85,
90,
94,
162,
201,
206,
280,
299 
 153   Monitor   Methamidophos   -   -   -   [12]
2,
11,
13,
19,
46,
49,
58,
70,
85,
98,
298,
300 
 154   Montelukast   Montelukast   D00529, D08229   [1] CYSLTR1   [2] Calcium signaling pathway, Neuroactive ligand-receptor interaction   [5]
13,
46,
85,
98,
228 
 155   Moxifloxacin   Moxifloxacin   D00874, D08237   -   -   [8]
2,
6,
46,
49,
85,
86,
240,
299 
 156   Mycophenolate   Mycophenolic acid   D05096   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [33]
2,
11,
13,
14,
19,
20,
28,
35,
36,
42,
43,
45,
49,
51,
53,
60,
62,
65,
66,
84,
85,
95,
96,
162,
164,
222,
224,
226,
234,
283,
284,
285,
300 
 157   Mycophenolate mofetil   Mycophenolate mofetil   D00752, D05094, D05095   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [32]
2,
11,
13,
14,
19,
20,
28,
35,
36,
42,
43,
45,
49,
51,
53,
60,
62,
65,
66,
85,
95,
96,
162,
164,
222,
224,
226,
234,
283,
284,
285,
300 
 158   N-acetyl cysteine   L-cysteine   D00026, D02326   -   -   [5]
13,
19,
85,
88,
296 
 159   N-acetylcysteine   Acetylcysteine   D00221   -   -   [10]
6,
13,
19,
20,
49,
58,
85,
111,
164,
299 
 160   N-acetylcysteine, (nac)   Acetylcysteine   D00221   -   -   [1]
85 
 161   Nalbuphine   Nalbuphine   D00843, D08246   [3] OPRD1, OPRK1, OPRM1   [5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway   [1]
85 
 162   Nalbuphine er   Nalbuphine   D00843, D08246   [3] OPRD1, OPRK1, OPRM1   [5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway   [1]
85 
 163   Nandrolone   Nandrolone   D08250   [1] AR   [3] Oocyte meiosis, Pathways in cancer, Prostate cancer   [2]
60,
85 
 164   Nandrolone decanoate   Nandrolone decanoate   D00955   [1] AR   [3] Oocyte meiosis, Pathways in cancer, Prostate cancer   [2]
60,
85 
 165   Nd-l02-s0201   -   -   -   -   [1]
85 
 166   Nintedanib   Nintedanib   D10481   [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB   [34] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway   [4]
51,
85,
89,
228 
 167   Nitric oxide   Nitric oxide   D00074   -   -   [7]
46,
85,
86,
98,
251,
294,
299 
 168   Octreotide   Octreotide   D00442, D06495   [1] SSTR2   [4] Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway   [7]
67,
75,
84,
85,
89,
193,
227 
 169   Ofev   Nintedanib   D10481   [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB   [34] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway   [4]
51,
85,
89,
228 
 170   Ofev 100 mg capsule   Nintedanib   D10481   [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB   [34] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway   [1]
85 
 171   Ofev 150 mg capsule   Nintedanib   D10481   [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB   [34] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway   [1]
85 
 172   Omeprazole   Omeprazole   D00455, D01207, D05259, D05261   [2] ATP4A, ATP4B   [4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation   [15]
6,
8,
13,
46,
51,
85,
96,
97,
98,
225,
271,
282,
294,
298,
299 
 173   Omeprazole (uk licensed generic product)   Omeprazole   D00455, D01207, D05259, D05261   [2] ATP4A, ATP4B   [4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation   [1]
85 
 174   Oxygen   Oxygen   D00003   -   -   [14]
46,
49,
70,
84,
85,
86,
88,
90,
96,
97,
193,
226,
299,
330 
 175   Oxygen 40 %   Oxygen   D00003   -   -   [1]
85 
 176   Pa101   -   -   -   -   [1]
85 
 177   Paclitaxel   Paclitaxel   D00491, D05333   [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8   [3] Gap junction, Pathogenic Escherichia coli infection, Phagosome   [2]
46,
85 
 178   Pamrevlumab   Pamrevlumab   D10969   [1] CCN2   [2] Apelin signaling pathway, Hippo signaling pathway   [2]
85,
113 
 179   Pbi4050   -   -   -   -   [2]
85,
299 
 180   Pir, s-7701   -   -   -   -   [1]
85 
 181   Pirfenidone   Pirfenidone   D01583   [6] CCL2, IL10, IL1A, IL1B, IL6, TNF   [80] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease (American trypanosomiasis), Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy (DCM), EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pertussis, Prion diseases, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [10]
34,
46,
50,
51,
58,
84,
85,
164,
222,
228 
 182   Pirfenidone and nintedanib   Pirfenidone   D01583   [6] CCL2, IL10, IL1A, IL1B, IL6, TNF   [80] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease (American trypanosomiasis), Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy (DCM), EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pertussis, Prion diseases, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [1]
85 
 183   Pirfenidone or nintedanib   Pirfenidone   D01583   [6] CCL2, IL10, IL1A, IL1B, IL6, TNF   [80] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease (American trypanosomiasis), Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy (DCM), EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pertussis, Prion diseases, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [1]
85 
 184   Pirfenidoneone   -   -   -   -   [1]
85 
 185   Placebo   -   -   -   -   [20]
3,
6,
13,
14,
40,
46,
49,
50,
51,
66,
67,
79,
85,
86,
88,
96,
97,
144,
149,
226 
 186   Pln-74809   -   -   -   -   [1]
85 
 187   Pomalidomide   Pomalidomide   D08976   [2] IL6, TNF   [76] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy (DCM), EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pertussis, Prion diseases, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [6]
28,
34,
51,
85,
227,
331 
 188   Pomalidomide (cc-4047   Pomalidomide   D08976   [2] IL6, TNF   [76] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy (DCM), EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pertussis, Prion diseases, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [1]
85 
 189   Prednisolone   Prednisolone   D00472, D00980, D00981, D00982, D01239, D01998, D02156, D03301   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [38]
11,
13,
25,
26,
35,
38,
39,
41,
43,
44,
45,
46,
49,
50,
51,
56,
60,
61,
63,
64,
65,
66,
75,
81,
84,
85,
95,
96,
97,
113,
145,
162,
222,
269,
271,
296,
299,
300 
 190   Prednisone   Prednisone   D00473   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [43]
2,
11,
13,
14,
26,
35,
40,
41,
42,
43,
44,
45,
46,
49,
50,
51,
53,
61,
63,
64,
65,
66,
81,
84,
85,
86,
95,
96,
97,
113,
162,
164,
222,
224,
228,
251,
283,
284,
285,
288,
299,
300,
331 
 191   Privigen 100mg/ml   -   -   -   -   [1]
85 
 192   Prm-151   -   -   -   -   [1]
85 
 193   Pzn 8881655(rochepharma ag)   -   -   -   -   [1]
85 
 194   Qax576   -   -   -   -   [4]
51,
85,
96,
98 
 195   Quercetin   Quercetin   -   -   -   [5]
84,
85,
192,
285,
299 
 196   Remicade   Infliximab   D02598   [1] TNF   [61] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Dilated cardiomyopathy (DCM), Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pathogenic Escherichia coli infection, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [8]
46,
49,
56,
84,
85,
96,
97,
271 
 197   Revatio   Sildenafil   D02229, D08514   [1] PDE5A   [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway   [2]
85,
86 
 198   Revatio 20 mg   Sildenafil   D02229, D08514   [1] PDE5A   [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway   [1]
85 
 199   Rituximab   Rituximab   D02994   [1] MS4A1   [1] Hematopoietic cell lineage   [42]
11,
13,
14,
17,
35,
36,
43,
44,
45,
46,
49,
50,
51,
52,
53,
56,
60,
61,
63,
64,
65,
66,
83,
84,
85,
86,
93,
94,
96,
97,
162,
222,
223,
229,
256,
271,
283,
284,
285,
288,
300,
331 
 200   Rixathon 500 mg   -   -   -   -   [1]
85 
 201   Ro 47-0203   Bosentan   D01227, D07538   [2] EDNRA, EDNRB   [9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [4]
51,
85,
86,
88 
 202   Ro0220912   -   -   -   -   [1]
85 
 203   Ro0280296   -   -   -   -   [1]
85 
 204   Ro5490255   -   -   -   -   [1]
85 
 205   Rvt-1601   -   -   -   -   [1]
85 
 206   Salbutamol   Salbutamol   D02147   [1] ADRB2   [8] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway   [8]
3,
11,
49,
85,
86,
228,
256,
299 
 207   Sar156597   -   -   -   -   [2]
51,
85 
 208   Septrin   -   -   -   -   [1]
85 
 209   Sildenafil   Sildenafil   D02229, D08514   [1] PDE5A   [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway   [15]
6,
46,
50,
51,
85,
86,
113,
210,
211,
212,
225,
226,
278,
294,
299 
 210   Sildenafil (50 mg)   Sildenafil   D02229, D08514   [1] PDE5A   [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway   [1]
85 
 211   Sildenafil and losartan   Sildenafil   D02229, D08514   [1] PDE5A   [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway   [1]
85 
 212   Sildenafil citrate   Sildenafil   D02229, D08514   [1] PDE5A   [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway   [4]
51,
85,
86,
225 
 213   Simtuzumab   Simtuzumab   -   -   -   [2]
85,
94 
 214   Sirolimus   Sirolimus   D00753   [1] MTOR   [43] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Choline metabolism in cancer, Colorectal cancer, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway   [30]
13,
17,
34,
35,
36,
46,
51,
60,
62,
63,
65,
66,
67,
85,
89,
96,
98,
137,
157,
158,
192,
222,
277,
278,
279,
280,
281,
283,
285,
331 
 215   Sivelestat   Sivelestat   D03788   [1] ELANE   [2] Systemic lupus erythematosus, Transcriptional misregulation in cancer   [3]
13,
85,
96 
 216   Sm04646   -   -   -   -   [1]
85 
 217   Standard of care   -   -   -   -   [8]
6,
13,
14,
49,
51,
64,
79,
85 
 218   Standard steroid treatment   -   -   -   -   [1]
85 
 219   Sub-study: fg-3019   -   -   -   -   [1]
85 
 220   Sub-study: nintedanib   Nintedanib   D10481   [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB   [34] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway   [1]
85 
 221   Sub-study: pirfenidone   Pirfenidone   D01583   [6] CCL2, IL10, IL1A, IL1B, IL6, TNF   [80] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease (American trypanosomiasis), Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy (DCM), EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pertussis, Prion diseases, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [1]
85 
 222   Sulfamethoxazole   Sulfamethoxazole   D00447   -   -   [4]
44,
49,
85,
299 
 223   Symbicort   Formoterol   D01373, D05277, D07990   [1] ADRB2   [8] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway   [2]
85,
228 
 224   Tacrolimus   Tacrolimus   D00107, D08556   [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   [30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway   [29]
2,
11,
13,
36,
46,
49,
50,
51,
53,
60,
61,
62,
65,
66,
85,
95,
96,
97,
113,
151,
158,
164,
222,
224,
226,
228,
283,
284,
299 
 225   Td139   Td139   -   -   -   [1]
85 
 226   Tetrathiomolybdate   Tetrathiomolybdate   -   -   -   [3]
85,
93,
171 
 227   Thalidomide   Thalidomide   D00754   [1] TNF   [61] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Dilated cardiomyopathy (DCM), Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pathogenic Escherichia coli infection, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [18]
2,
16,
20,
28,
49,
51,
53,
65,
84,
85,
94,
96,
97,
227,
271,
280,
298,
331 
 228   Thalidomide pharmion   Thalidomide   D00754   [1] TNF   [61] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Dilated cardiomyopathy (DCM), Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pathogenic Escherichia coli infection, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [3]
85,
96,
97 
 229   The standard steroid treatment, plasma exchange and rituximab   Rituximab   D02994   [1] MS4A1   [1] Hematopoietic cell lineage   [1]
85 
 230   Thiotepa   Thiotepa   D00583   -   -   [11]
13,
19,
20,
28,
51,
60,
65,
85,
96,
164,
284 
 231   Thrombomodulin alfa   Thrombomodulin alfa   D06410   [1] F2   [7] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton   [1]
85 
 232   Tiotropium   Tiotropium   -   -   -   [3]
55,
85,
299 
 233   Tipelukast   Tipelukast   D06659   [1] CYSLTR1   [2] Calcium signaling pathway, Neuroactive ligand-receptor interaction   [1]
85 
 234   Tracleer   Bosentan   D01227, D07538   [2] EDNRA, EDNRB   [9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [8]
13,
51,
84,
85,
86,
88,
210,
211 
 235   Tralokinumab   Tralokinumab   D09979   [1] IL13   [8] Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease (IBD), JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation   [2]
85,
97 
 236   Tralokinumab cohort 1   Tralokinumab   D09979   [1] IL13   [8] Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease (IBD), JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation   [1]
85 
 237   Tralokinumab cohort 2   Tralokinumab   D09979   [1] IL13   [8] Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease (IBD), JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation   [1]
85 
 238   Tralokinumab is a human recombinant monoclonal antibody (mab) of the subclass that specifically binds human il-13, blocking interactions with the il-13 receptor   Tralokinumab   D09979   [1] IL13   [8] Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease (IBD), JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation   [1]
85 
 239   Treatment as usual (tau)   -   -   -   -   [1]
85 
 240   Treprostinil   Treprostinil   D06213   [1] PTGIR   [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction   [5]
51,
84,
85,
86,
88 
 241   Treprostinil sodium for inhalation   Treprostinil   D06213   [1] PTGIR   [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction   [1]
85 
 242   Trimethoprim   Trimethoprim   D00145, D06236   -   -   [6]
36,
44,
49,
60,
85,
299 
 243   Trk-250   -   -   -   -   [1]
85 
 244   Valganciclovir   Valganciclovir   D02495   -   -   [6]
28,
60,
85,
97,
299,
331 
 245   Vasoactive intestinal peptide   -   -   -   -   [1]
85 
 246   Vay736   -   -   -   -   [7]
13,
35,
46,
49,
53,
85,
95 
 247   Vismodegib   Vismodegib   D09992   [1] SMO   [5] Axon guidance, Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer, Proteoglycans in cancer   [1]
85 
 248   Vrp700   -   -   -   -   [1]
85 
 249   Warfarin   Warfarin   D00564, D01280, D08682   [2] NQO1, VKORC1   [5] Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis   [10]
6,
8,
13,
19,
46,
49,
66,
85,
88,
96 
 250   Xenon   Xenon   D01901, D06339   -   -   [5]
22,
85,
228,
231,
299 
 251   Zileuton   Zileuton   D00414   [1] ALOX5   [6] Arachidonic acid metabolism, Fc epsilon RI signaling pathway, Metabolic pathways, Ovarian steroidogenesis, Serotonergic synapse, Toxoplasmosis   [3]
85,
160,
164 
 252   Zl-2102   -   -   -   -   [1]
85 
 253   Zsp1603 12.5 mg   -   -   -   -   [1]
85 
 254   Zsp1603 25 mg   -   -   -   -   [1]
85 
 255   Zsp1603 50 mg   -   -   -   -   [1]
85 
 256   Zsp1603 7.5 mg   -   -   -   -   [1]
85 

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