DDrare: Database of Drug Development for Rare Diseases

Target Gene/Pathway

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z other

210 / 275 pathways found* Show info (disease name, etc.) on mouse-over.

No.	KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related	KEGG GENES * [Number of genes]	KEGG DRUG *	DrugBank	Disease ID * [Number of diseases]
1	Acute myeloid leukemia 3 genes, 5 drugs (DrugBank), 43 diseases shown	[1] KIT	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
			D10229	Masitinib	[6] 2, 5, 6, 13, 46, 96
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[1] RARA	D06543	Vitamin A	[4] 13, 49, 53, 90
2	Adipocytokine signaling pathway 6 genes, 4 drugs (DrugBank), 46 diseases shown	[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[2] PRKAA1, PRKAA2	D00944	Metformin	[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299
			D04966
		[3] RXRA, RXRB, RXRG	D03106	Bexarotene	[2] 13, 75
3	Adrenergic signaling in cardiomyocytes 11 genes, 13 drugs (DrugBank), 38 diseases shown	[1] ADRA1A	D01692	Alfuzosin	[1] 13
			D07124
			D01965	Silodosin	[2] 6, 13
		[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2	D00095	Epinephrine	[9] 6, 13, 46, 86, 96, 168, 226, 231, 256
			D00996
			D02149
		[1] ADRB2	D08092	Isoxsuprine	[1] 13
			D02147	Salbutamol	[13] 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299
		[1] AGTR1	D00357	Losartan	[18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
			D08146
		[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4	D00332	Gabapentin	[7] 6, 13, 19, 70, 97, 226, 298
			D02716	Pregabalin	[5] 13, 36, 46, 70, 298
		[1] SCN5A	D00354	Lamotrigine	[3] 13, 34, 114
			D00358	Lidocaine	[10] 6, 13, 46, 84, 86, 97, 168, 226, 231, 256
			D02086
			D08127
			D00533	Oxcarbazepine	[1] 13
			D00512	Phenytoin	[1] 13
			D02103
			D00642	Quinidine	[3] 2, 8, 13
			D00643
			D02272
			D08458
4	African trypanosomiasis 2 genes, 1 drug (DrugBank), 16 diseases shown	[2] IL12A, IL12B	D09214	Ustekinumab	[16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271
5	AGE-RAGE signaling pathway in diabetic complications 2 genes, 2 drugs (DrugBank), 25 diseases shown	[1] AGTR1	D00357	Losartan	[18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
			D08146
		[1] VEGFA	D06409	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331
6	Alcoholism 10 genes, 12 drugs (DrugBank), 31 diseases shown	[2] ADORA2A, ADORA2B	D00045	Adenosine	[5] 13, 46, 53, 58, 65
		[1] DDC	D00558	Carbidopa	[8] 2, 4, 6, 13, 17, 90, 164, 201
		[1] DRD2	D01745	Domperidone	[5] 6, 13, 17, 51, 230
			D07868
			D00458	Quetiapine	[2] 6, 13
			D08456
		[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D	D00777	Amantadine	[4] 6, 8, 13, 127
			D07441
			D00848	Dextromethorphan	[9] 2, 6, 8, 13, 46, 78, 96, 97, 156
			D03742
			D03744
			D00711	Ketamine	[6] 6, 13, 70, 113, 156, 215
			D08098
			D04905	Memantine	[7] 2, 6, 8, 13, 49, 127, 205
			D08174
			D00775	Riluzole	[7] 2, 3, 5, 8, 13, 17, 206
		[1] SLC6A3	D03215	Armodafinil	[3] 6, 13, 84
			D08130	Lisdexamfetamine	[1] 13
			D01296	Methylphenidate	[7] 6, 13, 34, 84, 113, 179, 206
			D04999
7	Aldosterone synthesis and secretion 2 genes, 2 drugs (DrugBank), 26 diseases shown	[1] AGTR1	D00357	Losartan	[18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
			D08146
		[1] MC2R	D00146	Corticotropin	[12] 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222
8	Aldosterone-regulated sodium reabsorption 3 genes, 1 drug (DrugBank), 3 diseases shown	[3] SCNN1A, SCNN1B, SCNN1G	D00649	Amiloride	[3] 13, 225, 299
			D07447
9	Allograft rejection 24 genes, 3 drugs (DrugBank), 30 diseases shown	[2] CD80, CD86	D03203	Abatacept	[24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300
		[20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G	D04318	Glatiramer	[4] 2, 13, 96, 156
		[2] IL12A, IL12B	D09214	Ustekinumab	[16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271
10	Alzheimer disease 14 genes, 7 drugs (DrugBank), 42 diseases shown	[4] APH1A, NCSTN, PSEN1, PSENEN	D09010	Tarenflurbil	[1] 13
		[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D	D00777	Amantadine	[4] 6, 8, 13, 127
			D07441
			D00848	Dextromethorphan	[9] 2, 6, 8, 13, 46, 78, 96, 97, 156
			D03742
			D03744
			D00711	Ketamine	[6] 6, 13, 70, 113, 156, 215
			D08098
			D04905	Memantine	[7] 2, 6, 8, 13, 49, 127, 205
			D08174
			D00775	Riluzole	[7] 2, 3, 5, 8, 13, 17, 206
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
11	Amoebiasis 4 genes, 2 drugs (DrugBank), 24 diseases shown	[2] IL12A, IL12B	D09214	Ustekinumab	[16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271
		[2] IL1R1, IL1R2	D02934	Anakinra	[17] 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299
12	Amphetamine addiction 16 genes, 10 drugs (DrugBank), 48 diseases shown	[1] DDC	D00558	Carbidopa	[8] 2, 4, 6, 13, 17, 90, 164, 201
		[9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D	D00775	Riluzole	[7] 2, 3, 5, 8, 13, 17, 206
		[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D	D00777	Amantadine	[4] 6, 8, 13, 127
			D07441
			D00848	Dextromethorphan	[9] 2, 6, 8, 13, 46, 78, 96, 97, 156
			D03742
			D03744
			D00711	Ketamine	[6] 6, 13, 70, 113, 156, 215
			D08098
			D04905	Memantine	[7] 2, 6, 8, 13, 49, 127, 205
			D08174
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
		[1] SLC6A3	D03215	Armodafinil	[3] 6, 13, 84
			D08130	Lisdexamfetamine	[1] 13
			D01296	Methylphenidate	[7] 6, 13, 34, 84, 113, 179, 206
			D04999
13	AMPK signaling pathway 6 genes, 10 drugs (DrugBank), 66 diseases shown	[1] ADRA1A	D01692	Alfuzosin	[1] 13
			D07124
			D00095	Epinephrine	[9] 6, 13, 46, 86, 96, 168, 226, 231, 256
			D00996
			D02149
			D01965	Silodosin	[2] 6, 13
		[1] HMGCR	D00887	Atorvastatin	[17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299
			D07474
			D00893	Pravastatin	[9] 13, 46, 49, 67, 79, 96, 164, 265, 333
			D08410
			D00434	Simvastatin	[19] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[1] PPARG	D00945	Pioglitazone	[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
			D08378
		[2] PRKAA1, PRKAA2	D00944	Metformin	[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299
			D04966
14	Amyotrophic lateral sclerosis (ALS) 12 genes, 6 drugs (DrugBank), 42 diseases shown	[7] GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D	D00775	Riluzole	[7] 2, 3, 5, 8, 13, 17, 206
		[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D	D00777	Amantadine	[4] 6, 8, 13, 127
			D07441
			D00848	Dextromethorphan	[9] 2, 6, 8, 13, 46, 78, 96, 97, 156
			D03742
			D03744
			D00711	Ketamine	[6] 6, 13, 70, 113, 156, 215
			D08098
			D04905	Memantine	[7] 2, 6, 8, 13, 49, 127, 205
			D08174
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
15	Antifolate resistance 2 genes, 1 drug (DrugBank), 33 diseases shown	[2] DHFR, DHFR2	D00142	Methotrexate	[33] 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331
			D02115
16	Antigen processing and presentation 20 genes, 1 drug (DrugBank), 4 diseases shown	[20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G	D04318	Glatiramer	[4] 2, 13, 96, 156
17	Apelin signaling pathway 5 genes, 5 drugs (DrugBank), 53 diseases shown	[1] AGTR1	D00357	Losartan	[18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
			D08146
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[1] PDE3B	D01385	Ibudilast	[2] 2, 13
		[2] PRKAA1, PRKAA2	D00944	Metformin	[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299
			D04966
18	Arachidonic acid metabolism 2 genes, 6 drugs (DrugBank), 18 diseases shown	[2] PTGS1, PTGS2	D00217	Acetaminophen	[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271
			D00109	Acetylsalicylic acid	[10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231
			D00903	Diclofenac	[4] 13, 34, 46, 271
			D00904
			D07816
			D00330	Flurbiprofen	[2] 13, 46
			D01475
			D02290
			D00126	Ibuprofen	[6] 13, 46, 65, 113, 271, 299
			D01122
			D04490
			D06606
			D00118	Naproxen	[3] 13, 46, 271
19	Arrhythmogenic right ventricular cardiomyopathy (ARVC) 5 genes, 4 drugs (DrugBank), 13 diseases shown	[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4	D00332	Gabapentin	[7] 6, 13, 19, 70, 97, 226, 298
			D02716	Pregabalin	[5] 13, 36, 46, 70, 298
		[1] ITGA4	D06590	Firategrast	[1] 13
			D06886	Natalizumab	[6] 13, 15, 25, 46, 63, 96
20	Asthma 14 genes, 1 drug (DrugBank), 4 diseases shown	[14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5	D04318	Glatiramer	[4] 2, 13, 96, 156
21	Autoimmune thyroid disease 22 genes, 2 drugs (DrugBank), 26 diseases shown	[2] CD80, CD86	D03203	Abatacept	[24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300
		[20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G	D04318	Glatiramer	[4] 2, 13, 96, 156
22	Autophagy - animal 3 genes, 3 drugs (DrugBank), 46 diseases shown	[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[2] PRKAA1, PRKAA2	D00944	Metformin	[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299
			D04966
23	Autophagy - other 1 gene, 2 drugs (DrugBank), 36 diseases shown	[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
24	Axon guidance 8 genes, 4 drugs (DrugBank), 37 diseases shown	[1] ABL1	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
		[1] RGMA	D11355	Elezanumab	[1] 13
		[1] SEMA4D	D11469	Pepinemab	[2] 8, 13
25	B cell receptor signaling pathway 5 genes, 1 drug (DrugBank), 30 diseases shown	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
26	Bile secretion 3 genes, 5 drugs (DrugBank), 37 diseases shown	[1] CA2	D00218	Acetazolamide	[6] 13, 90, 115, 155, 225, 230
			D01196
		[1] HMGCR	D00887	Atorvastatin	[17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299
			D07474
			D00893	Pravastatin	[9] 13, 46, 49, 67, 79, 96, 164, 265, 333
			D08410
			D00434	Simvastatin	[19] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310
		[1] RXRA	D03106	Bexarotene	[2] 13, 75
27	Bladder cancer 1 gene, 1 drug (DrugBank), 9 diseases shown	[1] VEGFA	D06409	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331
28	Breast cancer 5 genes, 12 drugs (DrugBank), 44 diseases shown	[1] ESR1	D00554	Ethinylestradiol	[4] 13, 46, 49, 299
		[2] ESR1, ESR2	D00105	Estradiol	[5] 13, 46, 49, 226, 299
			D01413
			D01617
			D01953
			D04061
			D04063
			D04064
			D04065
			D00185	Estriol	[2] 13, 227
			D01986
		[1] KIT	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
			D10229	Masitinib	[6] 2, 5, 6, 13, 46, 96
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[1] PGR	D01217	Dydrogesterone	[1] 13
			D00950	Levonorgestrel	[1] 13
			D07222	Nomegestrol	[1] 13
			D08281	Nomegestrol acetate	[1] 13
			D00182	Norethisterone	[4] 13, 46, 49, 299
			D00953
29	C-type lectin receptor signaling pathway 9 genes, 8 drugs (DrugBank), 46 diseases shown	[3] IL12A, IL12B, IL23A	D09214	Ustekinumab	[16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
		[1] PTGS2	D00217	Acetaminophen	[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271
			D00109	Acetylsalicylic acid	[10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231
			D00903	Diclofenac	[4] 13, 34, 46, 271
			D00904
			D07816
			D00330	Flurbiprofen	[2] 13, 46
			D01475
			D02290
			D00126	Ibuprofen	[6] 13, 46, 65, 113, 271, 299
			D01122
			D04490
			D06606
			D00118	Naproxen	[3] 13, 46, 271
30	Caffeine metabolism 1 gene, 1 drug (DrugBank), 3 diseases shown	[1] XDH	D01206	Febuxostat	[3] 2, 6, 13
31	Calcium signaling pathway 28 genes, 28 drugs (DrugBank), 64 diseases shown	[2] ADORA2A, ADORA2B	D00045	Adenosine	[5] 13, 46, 53, 58, 65
		[1] ADRA1A	D01692	Alfuzosin	[1] 13
			D07124
			D01965	Silodosin	[2] 6, 13
		[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3	D00095	Epinephrine	[9] 6, 13, 46, 86, 96, 168, 226, 231, 256
			D00996
			D02149
		[1] ADRB2	D08092	Isoxsuprine	[1] 13
			D02147	Salbutamol	[13] 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299
		[1] ADRB3	D09535	Mirabegron	[3] 6, 13, 226
		[1] AGTR1	D00357	Losartan	[18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
			D08146
		[1] CHRM3	D01699	Darifenacin	[2] 6, 13
			D03654
		[1] CYSLTR1	D01385	Ibudilast	[2] 2, 13
			D00529	Montelukast	[5] 13, 46, 85, 98, 228
			D08229
		[2] EDNRA, EDNRB	D01227	Bosentan	[10] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211
			D07538
		[4] GRIN1, GRIN2A, GRIN2C, GRIN2D	D00777	Amantadine	[4] 6, 8, 13, 127
			D07441
			D00848	Dextromethorphan	[9] 2, 6, 8, 13, 46, 78, 96, 97, 156
			D03742
			D03744
			D00711	Ketamine	[6] 6, 13, 70, 113, 156, 215
			D08098
			D04905	Memantine	[7] 2, 6, 8, 13, 49, 127, 205
			D08174
			D00775	Riluzole	[7] 2, 3, 5, 8, 13, 17, 206
		[1] HRH1	D00664	Cetirizine	[2] 13, 35
			D07662
			D00666	Clemastine	[1] 13
			D03535
			D07803	Dexchlorpheniramine	[1] 13
			D00364	Loratadine	[3] 6, 13, 46
		[1] HRH2	D00422	Ranitidine	[2] 13, 65
			D00673
		[1] HTR2A	D00458	Quetiapine	[2] 6, 13
			D08456
		[2] HTR2A, HTR4	D00274	Cisapride	[1] 13
			D02092
		[1] HTR4	D09205	Prucalopride	[3] 13, 51, 96
		[1] PDGFRA	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
		[1] TBXA2R	D01128	Ramatroban	[1] 13
32	cAMP signaling pathway 25 genes, 20 drugs (DrugBank), 50 diseases shown	[2] ADORA1, ADORA2A	D00045	Adenosine	[5] 13, 46, 53, 58, 65
		[2] ADRB1, ADRB2	D00095	Epinephrine	[9] 6, 13, 46, 86, 96, 168, 226, 231, 256
			D00996
			D02149
		[1] ADRB2	D08092	Isoxsuprine	[1] 13
			D02147	Salbutamol	[13] 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299
		[1] DRD2	D01745	Domperidone	[5] 6, 13, 17, 51, 230
			D07868
			D00458	Quetiapine	[2] 6, 13
			D08456
		[1] EDNRA	D01227	Bosentan	[10] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211
			D07538
		[2] GABBR1, GABBR2	D09791	Arbaclofen	[2] 13, 206
			D08861	Arbaclofen Placarbil	[1] 13
			D00241	Baclofen	[5] 2, 10, 13, 18, 149
		[9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D	D00775	Riluzole	[7] 2, 3, 5, 8, 13, 17, 206
		[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D	D00777	Amantadine	[4] 6, 8, 13, 127
			D07441
			D00848	Dextromethorphan	[9] 2, 6, 8, 13, 46, 78, 96, 97, 156
			D03742
			D03744
			D00711	Ketamine	[6] 6, 13, 70, 113, 156, 215
			D08098
			D04905	Memantine	[7] 2, 6, 8, 13, 49, 127, 205
			D08174
		[1] HTR4	D00274	Cisapride	[1] 13
			D02092
			D09205	Prucalopride	[3] 13, 51, 96
		[1] MC2R	D00146	Corticotropin	[12] 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222
		[6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D	D01385	Ibudilast	[2] 2, 13
		[4] PDE4A, PDE4B, PDE4C, PDE4D	D01783	Rolipram	[2] 8, 13
33	Cardiac muscle contraction 4 genes, 2 drugs (DrugBank), 9 diseases shown	[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4	D00332	Gabapentin	[7] 6, 13, 19, 70, 97, 226, 298
			D02716	Pregabalin	[5] 13, 36, 46, 70, 298
34	Cell adhesion molecules (CAMs) 25 genes, 6 drugs (DrugBank), 33 diseases shown	[2] CD80, CD86	D03203	Abatacept	[24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300
		[20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G	D04318	Glatiramer	[4] 2, 13, 96, 156
		[1] ITGA4	D06590	Firategrast	[1] 13
			D06886	Natalizumab	[6] 13, 15, 25, 46, 63, 96
		[1] ITGAL	D03959	Efalizumab	[9] 11, 13, 37, 46, 49, 53, 61, 95, 96
		[1] PDCD1	D10316	Nivolumab	[10] 13, 26, 41, 46, 49, 50, 51, 53, 96, 97
35	Cell cycle 1 gene, 1 drug (DrugBank), 11 diseases shown	[1] ABL1	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
36	Cellular senescence 12 genes, 4 drugs (DrugBank), 50 diseases shown	[6] HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G	D04318	Glatiramer	[4] 2, 13, 96, 156
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
37	Central carbon metabolism in cancer 4 genes, 5 drugs (DrugBank), 43 diseases shown	[1] FGFR2	D05338	Palifermin	[4] 13, 38, 39, 65
		[1] KIT	D10229	Masitinib	[6] 2, 5, 6, 13, 46, 96
		[2] KIT, PDGFRA	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
38	cGMP-PKG signaling pathway 23 genes, 17 drugs (DrugBank), 59 diseases shown	[2] ADORA1, ADORA3	D00045	Adenosine	[5] 13, 46, 53, 58, 65
		[1] ADRA1A	D01692	Alfuzosin	[1] 13
			D07124
			D01965	Silodosin	[2] 6, 13
		[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3	D00095	Epinephrine	[9] 6, 13, 46, 86, 96, 168, 226, 231, 256
			D00996
			D02149
		[3] ADRA2A, ADRA2B, ADRA2C	D04375	Guanabenz	[2] 2, 13
			D00776	Tizanidine	[1] 13
			D08611
		[1] ADRB2	D08092	Isoxsuprine	[1] 13
			D02147	Salbutamol	[13] 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299
		[1] ADRB3	D09535	Mirabegron	[3] 6, 13, 226
		[1] AGTR1	D00357	Losartan	[18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
			D08146
		[2] EDNRA, EDNRB	D01227	Bosentan	[10] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211
			D07538
		[1] OPRD1	D00729	Loperamide	[2] 13, 97
			D07113
			D08144
			D02095	Naltrexone	[11] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97
			D05113
			D03783	Oxycodone	[7] 6, 13, 46, 70, 226, 231, 298
			D05312
			D05462
		[2] PDE3A, PDE3B	D01385	Ibudilast	[2] 2, 13
		[1] PDE5A	D02731	Vardenafil	[3] 13, 86, 299
			D03260
			D08668
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
39	Chagas disease (American trypanosomiasis) 2 genes, 1 drug (DrugBank), 16 diseases shown	[2] IL12A, IL12B	D09214	Ustekinumab	[16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271
40	Chemical carcinogenesis 1 gene, 6 drugs (DrugBank), 18 diseases shown	[1] PTGS2	D00217	Acetaminophen	[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271
			D00109	Acetylsalicylic acid	[10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231
			D00903	Diclofenac	[4] 13, 34, 46, 271
			D00904
			D07816
			D00330	Flurbiprofen	[2] 13, 46
			D01475
			D02290
			D00126	Ibuprofen	[6] 13, 46, 65, 113, 271, 299
			D01122
			D04490
			D06606
			D00118	Naproxen	[3] 13, 46, 271
41	Choline metabolism in cancer 2 genes, 3 drugs (DrugBank), 39 diseases shown	[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[1] PDGFRA	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
42	Cholinergic synapse 2 genes, 3 drugs (DrugBank), 9 diseases shown	[1] ACHE	D00670	Donepezil	[9] 5, 6, 13, 46, 78, 124, 127, 156, 206
			D07869
			D02558	Rivastigmine	[3] 5, 6, 13
			D03822
		[1] CHRM3	D01699	Darifenacin	[2] 6, 13
			D03654
43	Chronic myeloid leukemia 1 gene, 1 drug (DrugBank), 11 diseases shown	[1] ABL1	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
44	Circadian entrainment 11 genes, 6 drugs (DrugBank), 22 diseases shown	[9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D	D00775	Riluzole	[7] 2, 3, 5, 8, 13, 17, 206
		[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D	D00777	Amantadine	[4] 6, 8, 13, 127
			D07441
			D00848	Dextromethorphan	[9] 2, 6, 8, 13, 46, 78, 96, 97, 156
			D03742
			D03744
			D00711	Ketamine	[6] 6, 13, 70, 113, 156, 215
			D08098
			D04905	Memantine	[7] 2, 6, 8, 13, 49, 127, 205
			D08174
		[2] MTNR1A, MTNR1B	D08170	Melatonin	[8] 6, 13, 46, 49, 90, 97, 144, 202
45	Circadian rhythm 2 genes, 1 drug (DrugBank), 17 diseases shown	[2] PRKAA1, PRKAA2	D00944	Metformin	[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299
			D04966
46	Cocaine addiction 9 genes, 11 drugs (DrugBank), 28 diseases shown	[1] DDC	D00558	Carbidopa	[8] 2, 4, 6, 13, 17, 90, 164, 201
		[1] DRD2	D01745	Domperidone	[5] 6, 13, 17, 51, 230
			D07868
			D00458	Quetiapine	[2] 6, 13
			D08456
		[6] GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D	D00775	Riluzole	[7] 2, 3, 5, 8, 13, 17, 206
		[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D	D00777	Amantadine	[4] 6, 8, 13, 127
			D07441
			D00848	Dextromethorphan	[9] 2, 6, 8, 13, 46, 78, 96, 97, 156
			D03742
			D03744
			D00711	Ketamine	[6] 6, 13, 70, 113, 156, 215
			D08098
			D04905	Memantine	[7] 2, 6, 8, 13, 49, 127, 205
			D08174
		[1] SLC6A3	D03215	Armodafinil	[3] 6, 13, 84
			D08130	Lisdexamfetamine	[1] 13
			D01296	Methylphenidate	[7] 6, 13, 34, 84, 113, 179, 206
			D04999
47	Collecting duct acid secretion 3 genes, 3 drugs (DrugBank), 20 diseases shown	[2] ATP4A, ATP4B	D00455	Omeprazole	[15] 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
			D01207
			D05259
			D05261
			D02593	Pantoprazole	[2] 13, 65
			D05353
		[1] CA2	D00218	Acetazolamide	[6] 13, 90, 115, 155, 225, 230
			D01196
48	Colorectal cancer 1 gene, 2 drugs (DrugBank), 36 diseases shown	[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
49	Complement and coagulation cascades 1 gene, 1 drug (DrugBank), 7 diseases shown	[1] C5	D03940	Eculizumab	[7] 11, 13, 14, 62, 109, 222, 223
50	Cortisol synthesis and secretion 4 genes, 4 drugs (DrugBank), 29 diseases shown	[1] AGTR1	D00357	Losartan	[18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
			D08146
		[1] CYP17A1	D00351	Ketoconazole	[3] 8, 13, 75
		[1] KCNA4	D04127	Dalfampridine	[3] 3, 4, 13
		[1] MC2R	D00146	Corticotropin	[12] 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222
51	Cushing syndrome 4 genes, 4 drugs (DrugBank), 29 diseases shown	[1] AGTR1	D00357	Losartan	[18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
			D08146
		[1] CYP17A1	D00351	Ketoconazole	[3] 8, 13, 75
		[1] KCNA4	D04127	Dalfampridine	[3] 3, 4, 13
		[1] MC2R	D00146	Corticotropin	[12] 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222
52	Cytokine-cytokine receptor interaction 16 genes, 13 drugs (DrugBank), 66 diseases shown	[1] CSF3R	D03235	Filgrastim	[28] 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331
		[1] EPOR	D03231	Erythropoietin	[9] 2, 6, 13, 22, 46, 47, 70, 95, 96
		[1] GHR	D02691	Somatotropin	[18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299
		[2] IFNAR1, IFNAR2	D04554	Interferon beta-1a	[5] 13, 14, 26, 96, 97
			D00746	Interferon beta-1b	[1] 13
			D10483	Peginterferon beta-1a	[1] 13
		[3] IL12A, IL12B, IL23A	D09214	Ustekinumab	[16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271
		[1] IL17A	D09967	Secukinumab	[7] 13, 37, 41, 46, 160, 269, 271
		[2] IL1R1, IL1R2	D02934	Anakinra	[17] 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299
		[1] IL2RA	D03639	Daclizumab	[7] 13, 56, 60, 65, 97, 283, 284
		[1] IL6R	D02596	Tocilizumab	[16] 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331
		[1] LTB	D08866	Baminercept	[4] 13, 46, 53, 97
		[2] TNFSF13, TNFSF13B	D09704	Atacicept	[4] 13, 46, 49, 66
53	Dilated cardiomyopathy (DCM) 6 genes, 5 drugs (DrugBank), 17 diseases shown	[1] ADRB1	D00095	Epinephrine	[9] 6, 13, 46, 86, 96, 168, 226, 231, 256
			D00996
			D02149
		[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4	D00332	Gabapentin	[7] 6, 13, 19, 70, 97, 226, 298
			D02716	Pregabalin	[5] 13, 36, 46, 70, 298
		[1] ITGA4	D06590	Firategrast	[1] 13
			D06886	Natalizumab	[6] 13, 15, 25, 46, 63, 96
54	Dopaminergic synapse 13 genes, 17 drugs (DrugBank), 53 diseases shown	[1] DDC	D00558	Carbidopa	[8] 2, 4, 6, 13, 17, 90, 164, 201
		[1] DRD2	D01745	Domperidone	[5] 6, 13, 17, 51, 230
			D07868
			D00458	Quetiapine	[2] 6, 13
			D08456
		[6] GRIA1, GRIA2, GRIA3, GRIA4, GRIN2A, GRIN2B	D00775	Riluzole	[7] 2, 3, 5, 8, 13, 17, 206
		[2] GRIN2A, GRIN2B	D00777	Amantadine	[4] 6, 8, 13, 127
			D07441
			D00848	Dextromethorphan	[9] 2, 6, 8, 13, 46, 78, 96, 97, 156
			D03742
			D03744
			D00711	Ketamine	[6] 6, 13, 70, 113, 156, 215
			D08098
			D04905	Memantine	[7] 2, 6, 8, 13, 49, 127, 205
			D08174
		[3] PPP3CA, PPP3CB, PPP3CC	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
		[1] SCN1A	D00354	Lamotrigine	[3] 13, 34, 114
			D00358	Lidocaine	[10] 6, 13, 46, 84, 86, 97, 168, 226, 231, 256
			D02086
			D08127
			D00533	Oxcarbazepine	[1] 13
			D00512	Phenytoin	[1] 13
			D02103
			D00642	Quinidine	[3] 2, 8, 13
			D00643
			D02272
			D08458
		[1] SLC6A3	D03215	Armodafinil	[3] 6, 13, 84
			D08130	Lisdexamfetamine	[1] 13
			D01296	Methylphenidate	[7] 6, 13, 34, 84, 113, 179, 206
			D04999
55	Drug metabolism - other enzymes 5 genes, 6 drugs (DrugBank), 41 diseases shown	[2] IMPDH1, IMPDH2	D00752	Mycophenolate mofetil	[32] 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
			D05094
			D05095
			D05096	Mycophenolic acid	[34] 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
		[1] RRM1	D01370	Cladribine	[2] 13, 94
			D01907	Fludarabine	[17] 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326
			D07966
		[1] RRM2	D00341	Hydroxyurea	[8] 3, 13, 19, 20, 65, 85, 86, 284
		[1] XDH	D01206	Febuxostat	[3] 2, 6, 13
56	ECM-receptor interaction 2 genes, 3 drugs (DrugBank), 9 diseases shown	[1] ITGA4	D06590	Firategrast	[1] 13
			D06886	Natalizumab	[6] 13, 15, 25, 46, 63, 96
		[1] SV2A	D00709	Levetiracetam	[4] 2, 4, 6, 13
57	EGFR tyrosine kinase inhibitor resistance 5 genes, 6 drugs (DrugBank), 52 diseases shown	[1] FGFR2	D05338	Palifermin	[4] 13, 38, 39, 65
		[1] IL6R	D02596	Tocilizumab	[16] 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[1] PDGFRA	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
		[1] VEGFA	D06409	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331
58	Endocrine and other factor-regulated calcium reabsorption 2 genes, 4 drugs (DrugBank), 17 diseases shown	[1] ESR1	D00105	Estradiol	[5] 13, 46, 49, 226, 299
			D01413
			D01617
			D01953
			D04061
			D04063
			D04064
			D04065
			D00185	Estriol	[2] 13, 227
			D01986
			D00554	Ethinylestradiol	[4] 13, 46, 49, 299
		[1] VDR	D00188	Cholecalciferol	[15] 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299
59	Endocrine resistance 3 genes, 5 drugs (DrugBank), 39 diseases shown	[1] ESR1	D00554	Ethinylestradiol	[4] 13, 46, 49, 299
		[2] ESR1, ESR2	D00105	Estradiol	[5] 13, 46, 49, 226, 299
			D01413
			D01617
			D01953
			D04061
			D04063
			D04064
			D04065
			D00185	Estriol	[2] 13, 227
			D01986
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
60	Endocytosis 9 genes, 4 drugs (DrugBank), 22 diseases shown	[1] FGFR2	D05338	Palifermin	[4] 13, 38, 39, 65
		[6] HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G	D04318	Glatiramer	[4] 2, 13, 96, 156
		[1] IL2RA	D03639	Daclizumab	[7] 13, 56, 60, 65, 97, 283, 284
		[1] PDGFRA	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
61	Epstein-Barr virus infection 23 genes, 5 drugs (DrugBank), 14 diseases shown	[20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G	D04318	Glatiramer	[4] 2, 13, 96, 156
		[2] IFNAR1, IFNAR2	D04554	Interferon beta-1a	[5] 13, 14, 26, 96, 97
			D00746	Interferon beta-1b	[1] 13
			D10483	Peginterferon beta-1a	[1] 13
		[1] ITGAL	D03959	Efalizumab	[9] 11, 13, 37, 46, 49, 53, 61, 95, 96
62	ErbB signaling pathway 2 genes, 3 drugs (DrugBank), 39 diseases shown	[1] ABL1	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
63	Estrogen signaling pathway 7 genes, 15 drugs (DrugBank), 25 diseases shown	[1] ESR1	D00554	Ethinylestradiol	[4] 13, 46, 49, 299
		[2] ESR1, ESR2	D00105	Estradiol	[5] 13, 46, 49, 226, 299
			D01413
			D01617
			D01953
			D04061
			D04063
			D04064
			D04065
			D00185	Estriol	[2] 13, 227
			D01986
		[2] GABBR1, GABBR2	D09791	Arbaclofen	[2] 13, 206
			D08861	Arbaclofen Placarbil	[1] 13
			D00241	Baclofen	[5] 2, 10, 13, 18, 149
		[1] OPRM1	D00729	Loperamide	[2] 13, 97
			D07113
			D08144
			D02095	Naltrexone	[11] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97
			D05113
			D03783	Oxycodone	[7] 6, 13, 46, 70, 226, 231, 298
			D05312
			D05462
		[1] PGR	D01217	Dydrogesterone	[1] 13
			D00950	Levonorgestrel	[1] 13
			D07222	Nomegestrol	[1] 13
			D08281	Nomegestrol acetate	[1] 13
			D00182	Norethisterone	[4] 13, 46, 49, 299
			D00953
		[1] RARA	D06543	Vitamin A	[4] 13, 49, 53, 90
64	Fluid shear stress and atherosclerosis 7 genes, 5 drugs (DrugBank), 41 diseases shown	[2] IL1R1, IL1R2	D02934	Anakinra	[17] 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299
		[1] KEAP1	D03846	Dimethyl fumarate	[5] 13, 46, 49, 51, 86
		[1] NQO1	D00564	Warfarin	[10] 6, 8, 13, 19, 46, 49, 66, 85, 88, 96
			D01280
			D08682
		[2] PRKAA1, PRKAA2	D00944	Metformin	[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299
			D04966
		[1] VEGFA	D06409	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331
65	Focal adhesion 3 genes, 4 drugs (DrugBank), 18 diseases shown	[1] ITGA4	D06590	Firategrast	[1] 13
			D06886	Natalizumab	[6] 13, 15, 25, 46, 63, 96
		[1] PDGFRA	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
		[1] VEGFA	D06409	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331
66	Folate biosynthesis 2 genes, 1 drug (DrugBank), 33 diseases shown	[2] DHFR, DHFR2	D00142	Methotrexate	[33] 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331
			D02115
67	FoxO signaling pathway 4 genes, 5 drugs (DrugBank), 23 diseases shown	[2] PRKAA1, PRKAA2	D00944	Metformin	[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299
			D04966
		[1] S1PR1	D10001	Fingolimod	[4] 2, 13, 14, 156
			D11215	Ponesimod	[1] 13
			D11460	Siponimod	[2] 13, 50
		[2] S1PR1, S1PR4	D10968	Ozanimod	[3] 13, 96, 97
68	GABAergic synapse 19 genes, 7 drugs (DrugBank), 17 diseases shown	[2] GABBR1, GABBR2	D09791	Arbaclofen	[2] 13, 206
			D08861	Arbaclofen Placarbil	[1] 13
			D00241	Baclofen	[5] 2, 10, 13, 18, 149
		[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ	D02624	Eszopiclone	[3] 6, 13, 46
			D00697	Flumazenil	[5] 6, 13, 17, 18, 206
			D00550	Midazolam	[10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298
			D00696
			D05028
		[1] SLC6A1	D00332	Gabapentin	[7] 6, 13, 19, 70, 97, 226, 298
69	Gap junction 4 genes, 5 drugs (DrugBank), 19 diseases shown	[1] ADRB1	D00095	Epinephrine	[9] 6, 13, 46, 86, 96, 168, 226, 231, 256
			D00996
			D02149
		[1] DRD2	D01745	Domperidone	[5] 6, 13, 17, 51, 230
			D07868
		[2] DRD2, HTR2A	D00458	Quetiapine	[2] 6, 13
			D08456
		[1] HTR2A	D00274	Cisapride	[1] 13
			D02092
		[1] PDGFRA	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
70	Gastric acid secretion 5 genes, 5 drugs (DrugBank), 20 diseases shown	[2] ATP4A, ATP4B	D00455	Omeprazole	[15] 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
			D01207
			D05259
			D05261
			D02593	Pantoprazole	[2] 13, 65
			D05353
		[1] CA2	D00218	Acetazolamide	[6] 13, 90, 115, 155, 225, 230
			D01196
		[1] CHRM3	D01699	Darifenacin	[2] 6, 13
			D03654
		[1] HRH2	D00422	Ranitidine	[2] 13, 65
			D00673
71	Gastric cancer 6 genes, 5 drugs (DrugBank), 41 diseases shown	[1] FGFR2	D05338	Palifermin	[4] 13, 38, 39, 65
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[1] RARB	D06543	Vitamin A	[4] 13, 49, 53, 90
		[3] RXRA, RXRB, RXRG	D03106	Bexarotene	[2] 13, 75
72	Glioma 2 genes, 3 drugs (DrugBank), 39 diseases shown	[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[1] PDGFRA	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
73	Glucagon signaling pathway 8 genes, 3 drugs (DrugBank), 40 diseases shown	[1] PDE3B	D01385	Ibudilast	[2] 2, 13
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
		[2] PRKAA1, PRKAA2	D00944	Metformin	[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299
			D04966
74	Glutamatergic synapse 19 genes, 6 drugs (DrugBank), 42 diseases shown	[14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D	D00775	Riluzole	[7] 2, 3, 5, 8, 13, 17, 206
		[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D	D00777	Amantadine	[4] 6, 8, 13, 127
			D07441
			D00848	Dextromethorphan	[9] 2, 6, 8, 13, 46, 78, 96, 97, 156
			D03742
			D03744
			D00711	Ketamine	[6] 6, 13, 70, 113, 156, 215
			D08098
			D04905	Memantine	[7] 2, 6, 8, 13, 49, 127, 205
			D08174
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
75	Glutathione metabolism 2 genes, 3 drugs (DrugBank), 22 diseases shown	[1] RRM1	D01370	Cladribine	[2] 13, 94
			D01907	Fludarabine	[17] 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326
			D07966
		[1] RRM2	D00341	Hydroxyurea	[8] 3, 13, 19, 20, 65, 85, 86, 284
76	Glycerophospholipid metabolism 1 gene, 2 drugs (DrugBank), 9 diseases shown	[1] ACHE	D00670	Donepezil	[9] 5, 6, 13, 46, 78, 124, 127, 156, 206
			D07869
			D02558	Rivastigmine	[3] 5, 6, 13
			D03822
77	GnRH secretion 3 genes, 5 drugs (DrugBank), 11 diseases shown	[1] ESR2	D00105	Estradiol	[5] 13, 46, 49, 226, 299
			D01413
			D01617
			D01953
			D04061
			D04063
			D04064
			D04065
			D00185	Estriol	[2] 13, 227
			D01986
		[2] GABBR1, GABBR2	D09791	Arbaclofen	[2] 13, 206
			D08861	Arbaclofen Placarbil	[1] 13
			D00241	Baclofen	[5] 2, 10, 13, 18, 149
78	Graft-versus-host disease 22 genes, 2 drugs (DrugBank), 26 diseases shown	[2] CD80, CD86	D03203	Abatacept	[24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300
		[20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G	D04318	Glatiramer	[4] 2, 13, 96, 156
79	Growth hormone synthesis, secretion and action 3 genes, 4 drugs (DrugBank), 50 diseases shown	[1] GHR	D02691	Somatotropin	[18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299
		[1] GHRHR	D08523	Somatorelin	[2] 13, 78
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
80	Hematopoietic cell lineage 23 genes, 14 drugs (DrugBank), 72 diseases shown	[1] CSF3R	D03235	Filgrastim	[28] 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331
		[1] EPOR	D03231	Erythropoietin	[9] 2, 6, 13, 22, 46, 47, 70, 95, 96
		[14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5	D04318	Glatiramer	[4] 2, 13, 96, 156
		[2] IL1R1, IL1R2	D02934	Anakinra	[17] 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299
		[1] IL2RA	D03639	Daclizumab	[7] 13, 56, 60, 65, 97, 283, 284
		[1] IL6R	D02596	Tocilizumab	[16] 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331
		[1] ITGA4	D06590	Firategrast	[1] 13
			D06886	Natalizumab	[6] 13, 15, 25, 46, 63, 96
		[1] KIT	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
			D10229	Masitinib	[6] 2, 5, 6, 13, 46, 96
		[1] MS4A1	D05218	Ocrelizumab	[3] 13, 46, 49
			D09314	Ofatumumab	[3] 13, 35, 46
			D02994	Rituximab	[42] 11, 13, 14, 17, 35, 36, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 223, 229, 256, 271, 283, 284, 285, 288, 300, 331
			D11243	Ublituximab	[1] 13
81	Hepatitis B 1 gene, 3 drugs (DrugBank), 5 diseases shown	[1] IFNAR1	D04554	Interferon beta-1a	[5] 13, 14, 26, 96, 97
			D00746	Interferon beta-1b	[1] 13
			D10483	Peginterferon beta-1a	[1] 13
82	Hepatitis C 3 genes, 4 drugs (DrugBank), 6 diseases shown	[2] IFNAR1, IFNAR2	D04554	Interferon beta-1a	[5] 13, 14, 26, 96, 97
			D00746	Interferon beta-1b	[1] 13
			D10483	Peginterferon beta-1a	[1] 13
		[1] RXRA	D03106	Bexarotene	[2] 13, 75
83	Hepatocellular carcinoma 3 genes, 4 drugs (DrugBank), 40 diseases shown	[1] KEAP1	D03846	Dimethyl fumarate	[5] 13, 46, 49, 51, 86
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[1] NQO1	D00564	Warfarin	[10] 6, 8, 13, 19, 46, 49, 66, 85, 88, 96
			D01280
			D08682
84	Herpes simplex virus 1 infection 26 genes, 8 drugs (DrugBank), 53 diseases shown	[1] C5	D03940	Eculizumab	[7] 11, 13, 14, 62, 109, 222, 223
		[20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G	D04318	Glatiramer	[4] 2, 13, 96, 156
		[2] IFNAR1, IFNAR2	D04554	Interferon beta-1a	[5] 13, 14, 26, 96, 97
			D00746	Interferon beta-1b	[1] 13
			D10483	Peginterferon beta-1a	[1] 13
		[2] IL12A, IL12B	D09214	Ustekinumab	[16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
85	HIF-1 signaling pathway 3 genes, 4 drugs (DrugBank), 48 diseases shown	[1] IL6R	D02596	Tocilizumab	[16] 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[1] VEGFA	D06409	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331
86	Human cytomegalovirus infection 17 genes, 14 drugs (DrugBank), 72 diseases shown	[6] HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G	D04318	Glatiramer	[4] 2, 13, 96, 156
		[1] IL1R1	D02934	Anakinra	[17] 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299
		[1] IL6R	D02596	Tocilizumab	[16] 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[1] PDGFRA	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
		[1] PTGS2	D00217	Acetaminophen	[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271
			D00109	Acetylsalicylic acid	[10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231
			D00903	Diclofenac	[4] 13, 34, 46, 271
			D00904
			D07816
			D00330	Flurbiprofen	[2] 13, 46
			D01475
			D02290
			D00126	Ibuprofen	[6] 13, 46, 65, 113, 271, 299
			D01122
			D04490
			D06606
			D00118	Naproxen	[3] 13, 46, 271
		[1] VEGFA	D06409	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331
87	Human immunodeficiency virus 1 infection 12 genes, 4 drugs (DrugBank), 50 diseases shown	[6] HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G	D04318	Glatiramer	[4] 2, 13, 96, 156
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
88	Human papillomavirus infection 13 genes, 16 drugs (DrugBank), 51 diseases shown	[6] HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G	D04318	Glatiramer	[4] 2, 13, 96, 156
		[2] IFNAR1, IFNAR2	D04554	Interferon beta-1a	[5] 13, 14, 26, 96, 97
			D00746	Interferon beta-1b	[1] 13
			D10483	Peginterferon beta-1a	[1] 13
		[1] ITGA4	D06590	Firategrast	[1] 13
			D06886	Natalizumab	[6] 13, 15, 25, 46, 63, 96
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[1] PSEN1	D09010	Tarenflurbil	[1] 13
		[1] PTGS2	D00217	Acetaminophen	[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271
			D00109	Acetylsalicylic acid	[10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231
			D00903	Diclofenac	[4] 13, 34, 46, 271
			D00904
			D07816
			D00330	Flurbiprofen	[2] 13, 46
			D01475
			D02290
			D00126	Ibuprofen	[6] 13, 46, 65, 113, 271, 299
			D01122
			D04490
			D06606
			D00118	Naproxen	[3] 13, 46, 271
		[1] VEGFA	D06409	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331
89	Human T-cell leukemia virus 1 infection 30 genes, 6 drugs (DrugBank), 45 diseases shown	[1] FDPS	D01968	Zoledronic acid	[11] 6, 13, 46, 65, 93, 95, 96, 271, 274, 299, 333
			D06378
			D06379
			D08689
		[20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G	D04318	Glatiramer	[4] 2, 13, 96, 156
		[2] IL1R1, IL1R2	D02934	Anakinra	[17] 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299
		[1] IL2RA	D03639	Daclizumab	[7] 13, 56, 60, 65, 97, 283, 284
		[1] ITGAL	D03959	Efalizumab	[9] 11, 13, 37, 46, 49, 53, 61, 95, 96
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
90	Huntington disease 3 genes, 6 drugs (DrugBank), 29 diseases shown	[2] GRIN1, GRIN2B	D00777	Amantadine	[4] 6, 8, 13, 127
			D07441
			D00848	Dextromethorphan	[9] 2, 6, 8, 13, 46, 78, 96, 97, 156
			D03742
			D03744
			D00711	Ketamine	[6] 6, 13, 70, 113, 156, 215
			D08098
			D04905	Memantine	[7] 2, 6, 8, 13, 49, 127, 205
			D08174
			D00775	Riluzole	[7] 2, 3, 5, 8, 13, 17, 206
		[1] PPARG	D00945	Pioglitazone	[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
			D08378
91	Hypertrophic cardiomyopathy (HCM) 7 genes, 5 drugs (DrugBank), 27 diseases shown	[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4	D00332	Gabapentin	[7] 6, 13, 19, 70, 97, 226, 298
			D02716	Pregabalin	[5] 13, 36, 46, 70, 298
		[1] ITGA4	D06590	Firategrast	[1] 13
			D06886	Natalizumab	[6] 13, 15, 25, 46, 63, 96
		[2] PRKAA1, PRKAA2	D00944	Metformin	[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299
			D04966
92	IL-17 signaling pathway 2 genes, 7 drugs (DrugBank), 22 diseases shown	[1] IL17A	D09967	Secukinumab	[7] 13, 37, 41, 46, 160, 269, 271
		[1] PTGS2	D00217	Acetaminophen	[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271
			D00109	Acetylsalicylic acid	[10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231
			D00903	Diclofenac	[4] 13, 34, 46, 271
			D00904
			D07816
			D00330	Flurbiprofen	[2] 13, 46
			D01475
			D02290
			D00126	Ibuprofen	[6] 13, 46, 65, 113, 271, 299
			D01122
			D04490
			D06606
			D00118	Naproxen	[3] 13, 46, 271
93	Inflammatory bowel disease (IBD) 18 genes, 3 drugs (DrugBank), 19 diseases shown	[14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5	D04318	Glatiramer	[4] 2, 13, 96, 156
		[3] IL12A, IL12B, IL23A	D09214	Ustekinumab	[16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271
		[1] IL17A	D09967	Secukinumab	[7] 13, 37, 41, 46, 160, 269, 271
94	Inflammatory mediator regulation of TRP channels 3 genes, 7 drugs (DrugBank), 19 diseases shown	[1] HRH1	D00664	Cetirizine	[2] 13, 35
			D07662
			D00666	Clemastine	[1] 13
			D03535
			D07803	Dexchlorpheniramine	[1] 13
			D00364	Loratadine	[3] 6, 13, 46
		[1] HTR2A	D00274	Cisapride	[1] 13
			D02092
			D00458	Quetiapine	[2] 6, 13
			D08456
		[1] IL1R1	D02934	Anakinra	[17] 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299
95	Influenza A 19 genes, 6 drugs (DrugBank), 25 diseases shown	[1] FDPS	D01968	Zoledronic acid	[11] 6, 13, 46, 65, 93, 95, 96, 271, 274, 299, 333
			D06378
			D06379
			D08689
		[14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5	D04318	Glatiramer	[4] 2, 13, 96, 156
		[2] IFNAR1, IFNAR2	D04554	Interferon beta-1a	[5] 13, 14, 26, 96, 97
			D00746	Interferon beta-1b	[1] 13
			D10483	Peginterferon beta-1a	[1] 13
		[2] IL12A, IL12B	D09214	Ustekinumab	[16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271
96	Insulin resistance 3 genes, 3 drugs (DrugBank), 46 diseases shown	[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[2] PRKAA1, PRKAA2	D00944	Metformin	[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299
			D04966
97	Insulin secretion 2 genes, 2 drugs (DrugBank), 13 diseases shown	[1] CHRM3	D01699	Darifenacin	[2] 6, 13
			D03654
		[1] SNAP25	D00783	Botulinum toxin type A	[13] 2, 5, 6, 7, 13, 15, 17, 36, 51, 70, 113, 149, 226
98	Insulin signaling pathway 4 genes, 4 drugs (DrugBank), 46 diseases shown	[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[1] PDE3B	D01385	Ibudilast	[2] 2, 13
		[2] PRKAA1, PRKAA2	D00944	Metformin	[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299
			D04966
99	Intestinal immune network for IgA production 19 genes, 5 drugs (DrugBank), 30 diseases shown	[2] CD80, CD86	D03203	Abatacept	[24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300
		[14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5	D04318	Glatiramer	[4] 2, 13, 96, 156
		[1] ITGA4	D06590	Firategrast	[1] 13
			D06886	Natalizumab	[6] 13, 15, 25, 46, 63, 96
		[2] TNFSF13, TNFSF13B	D09704	Atacicept	[4] 13, 46, 49, 66
100	JAK-STAT signaling pathway 12 genes, 12 drugs (DrugBank), 82 diseases shown	[1] CSF3R	D03235	Filgrastim	[28] 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331
		[1] EPOR	D03231	Erythropoietin	[9] 2, 6, 13, 22, 46, 47, 70, 95, 96
		[1] GHR	D02691	Somatotropin	[18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299
		[2] IFNAR1, IFNAR2	D04554	Interferon beta-1a	[5] 13, 14, 26, 96, 97
			D00746	Interferon beta-1b	[1] 13
			D10483	Peginterferon beta-1a	[1] 13
		[3] IL12A, IL12B, IL23A	D09214	Ustekinumab	[16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271
		[1] IL2RA	D03639	Daclizumab	[7] 13, 56, 60, 65, 97, 283, 284
		[1] IL6R	D02596	Tocilizumab	[16] 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[1] PDGFRA	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
101	Kaposi sarcoma-associated herpesvirus infection 17 genes, 15 drugs (DrugBank), 68 diseases shown	[1] CD86	D03203	Abatacept	[24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300
		[6] HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G	D04318	Glatiramer	[4] 2, 13, 96, 156
		[2] IFNAR1, IFNAR2	D04554	Interferon beta-1a	[5] 13, 14, 26, 96, 97
			D00746	Interferon beta-1b	[1] 13
			D10483	Peginterferon beta-1a	[1] 13
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
		[1] PTGS2	D00217	Acetaminophen	[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271
			D00109	Acetylsalicylic acid	[10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231
			D00903	Diclofenac	[4] 13, 34, 46, 271
			D00904
			D07816
			D00330	Flurbiprofen	[2] 13, 46
			D01475
			D02290
			D00126	Ibuprofen	[6] 13, 46, 65, 113, 271, 299
			D01122
			D04490
			D06606
			D00118	Naproxen	[3] 13, 46, 271
		[1] VEGFA	D06409	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331
102	Legionellosis 2 genes, 1 drug (DrugBank), 16 diseases shown	[2] IL12A, IL12B	D09214	Ustekinumab	[16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271
103	Leishmaniasis 18 genes, 10 drugs (DrugBank), 34 diseases shown	[14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5	D04318	Glatiramer	[4] 2, 13, 96, 156
		[2] IL12A, IL12B	D09214	Ustekinumab	[16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271
		[1] ITGA4	D06590	Firategrast	[1] 13
			D06886	Natalizumab	[6] 13, 15, 25, 46, 63, 96
		[1] PTGS2	D00217	Acetaminophen	[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271
			D00109	Acetylsalicylic acid	[10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231
			D00903	Diclofenac	[4] 13, 34, 46, 271
			D00904
			D07816
			D00330	Flurbiprofen	[2] 13, 46
			D01475
			D02290
			D00126	Ibuprofen	[6] 13, 46, 65, 113, 271, 299
			D01122
			D04490
			D06606
			D00118	Naproxen	[3] 13, 46, 271
104	Leukocyte transendothelial migration 2 genes, 3 drugs (DrugBank), 12 diseases shown	[1] ITGA4	D06590	Firategrast	[1] 13
			D06886	Natalizumab	[6] 13, 15, 25, 46, 63, 96
		[1] ITGAL	D03959	Efalizumab	[9] 11, 13, 37, 46, 49, 53, 61, 95, 96
105	Long-term depression 3 genes, 1 drug (DrugBank), 7 diseases shown	[3] GRIA1, GRIA2, GRIA3	D00775	Riluzole	[7] 2, 3, 5, 8, 13, 17, 206
106	Long-term potentiation 12 genes, 6 drugs (DrugBank), 42 diseases shown	[7] GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D	D00775	Riluzole	[7] 2, 3, 5, 8, 13, 17, 206
		[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D	D00777	Amantadine	[4] 6, 8, 13, 127
			D07441
			D00848	Dextromethorphan	[9] 2, 6, 8, 13, 46, 78, 96, 97, 156
			D03742
			D03744
			D00711	Ketamine	[6] 6, 13, 70, 113, 156, 215
			D08098
			D04905	Memantine	[7] 2, 6, 8, 13, 49, 127, 205
			D08174
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
107	Longevity regulating pathway 4 genes, 4 drugs (DrugBank), 50 diseases shown	[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[1] PPARG	D00945	Pioglitazone	[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
			D08378
		[2] PRKAA1, PRKAA2	D00944	Metformin	[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299
			D04966
108	Longevity regulating pathway - multiple species 3 genes, 3 drugs (DrugBank), 46 diseases shown	[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[2] PRKAA1, PRKAA2	D00944	Metformin	[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299
			D04966
109	Malaria 2 genes, 2 drugs (DrugBank), 19 diseases shown	[1] IL12A	D09214	Ustekinumab	[16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271
		[1] ITGAL	D03959	Efalizumab	[9] 11, 13, 37, 46, 49, 53, 61, 95, 96
110	MAPK signaling pathway 14 genes, 8 drugs (DrugBank), 54 diseases shown	[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4	D00332	Gabapentin	[7] 6, 13, 19, 70, 97, 226, 298
			D02716	Pregabalin	[5] 13, 36, 46, 70, 298
		[1] FGFR2	D05338	Palifermin	[4] 13, 38, 39, 65
		[1] IL1R1	D02934	Anakinra	[17] 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299
		[1] KIT	D10229	Masitinib	[6] 2, 5, 6, 13, 46, 96
		[2] KIT, PDGFRA	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
		[1] VEGFA	D06409	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331
111	Measles 5 genes, 5 drugs (DrugBank), 21 diseases shown	[2] IFNAR1, IFNAR2	D04554	Interferon beta-1a	[5] 13, 14, 26, 96, 97
			D00746	Interferon beta-1b	[1] 13
			D10483	Peginterferon beta-1a	[1] 13
		[2] IL12A, IL12B	D09214	Ustekinumab	[16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271
		[1] IL2RA	D03639	Daclizumab	[7] 13, 56, 60, 65, 97, 283, 284
112	Melanogenesis 2 genes, 3 drugs (DrugBank), 21 diseases shown	[1] EDNRB	D01227	Bosentan	[10] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211
			D07538
		[1] KIT	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
			D10229	Masitinib	[6] 2, 5, 6, 13, 46, 96
113	Melanoma 1 gene, 1 drug (DrugBank), 11 diseases shown	[1] PDGFRA	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
114	Metabolic pathways 38 genes, 27 drugs (DrugBank), 87 diseases shown	[2] ATP4A, ATP4B	D00455	Omeprazole	[15] 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
			D01207
			D05259
			D05261
			D02593	Pantoprazole	[2] 13, 65
			D05353
		[13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9	D00218	Acetazolamide	[6] 13, 90, 115, 155, 225, 230
			D01196
		[1] CYP17A1	D00351	Ketoconazole	[3] 8, 13, 75
		[1] DDC	D00558	Carbidopa	[8] 2, 4, 6, 13, 17, 90, 164, 201
		[2] DHFR, DHFR2	D00142	Methotrexate	[33] 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331
			D02115
		[1] DHODH	D10172	Teriflunomide	[2] 13, 25
		[1] FDPS	D01968	Zoledronic acid	[11] 6, 13, 46, 65, 93, 95, 96, 271, 274, 299, 333
			D06378
			D06379
			D08689
		[1] HMGCR	D00887	Atorvastatin	[17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299
			D07474
			D00893	Pravastatin	[9] 13, 46, 49, 67, 79, 96, 164, 265, 333
			D08410
			D00434	Simvastatin	[19] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310
		[2] IMPDH1, IMPDH2	D00752	Mycophenolate mofetil	[32] 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
			D05094
			D05095
			D05096	Mycophenolic acid	[34] 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
		[2] NQO1, VKORC1	D00564	Warfarin	[10] 6, 8, 13, 19, 46, 49, 66, 85, 88, 96
			D01280
			D08682
		[6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D	D01385	Ibudilast	[2] 2, 13
		[4] PDE4A, PDE4B, PDE4C, PDE4D	D01783	Rolipram	[2] 8, 13
		[1] PDE5A	D02731	Vardenafil	[3] 13, 86, 299
			D03260
			D08668
		[2] PTGS1, PTGS2	D00217	Acetaminophen	[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271
			D00109	Acetylsalicylic acid	[10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231
			D00903	Diclofenac	[4] 13, 34, 46, 271
			D00904
			D07816
			D00330	Flurbiprofen	[2] 13, 46
			D01475
			D02290
			D00126	Ibuprofen	[6] 13, 46, 65, 113, 271, 299
			D01122
			D04490
			D06606
			D00118	Naproxen	[3] 13, 46, 271
		[1] RRM1	D01370	Cladribine	[2] 13, 94
			D01907	Fludarabine	[17] 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326
			D07966
		[1] RRM2	D00341	Hydroxyurea	[8] 3, 13, 19, 20, 65, 85, 86, 284
		[1] XDH	D01206	Febuxostat	[3] 2, 6, 13
115	MicroRNAs in cancer 5 genes, 10 drugs (DrugBank), 48 diseases shown	[2] ABL1, PDGFRA	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[1] PTGS2	D00217	Acetaminophen	[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271
			D00109	Acetylsalicylic acid	[10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231
			D00903	Diclofenac	[4] 13, 34, 46, 271
			D00904
			D07816
			D00330	Flurbiprofen	[2] 13, 46
			D01475
			D02290
			D00126	Ibuprofen	[6] 13, 46, 65, 113, 271, 299
			D01122
			D04490
			D06606
			D00118	Naproxen	[3] 13, 46, 271
		[1] VEGFA	D06409	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331
116	Mineral absorption 2 genes, 2 drugs (DrugBank), 16 diseases shown	[1] CLCN2	D04790	Lubiprostone	[4] 6, 13, 290, 299
		[1] VDR	D00188	Cholecalciferol	[15] 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299
117	Morphine addiction 26 genes, 12 drugs (DrugBank), 26 diseases shown	[1] ADORA1	D00045	Adenosine	[5] 13, 46, 53, 58, 65
		[2] GABBR1, GABBR2	D09791	Arbaclofen	[2] 13, 206
			D08861	Arbaclofen Placarbil	[1] 13
			D00241	Baclofen	[5] 2, 10, 13, 18, 149
		[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ	D02624	Eszopiclone	[3] 6, 13, 46
			D00697	Flumazenil	[5] 6, 13, 17, 18, 206
			D00550	Midazolam	[10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298
			D00696
			D05028
		[1] OPRM1	D00729	Loperamide	[2] 13, 97
			D07113
			D08144
			D02095	Naltrexone	[11] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97
			D05113
			D03783	Oxycodone	[7] 6, 13, 46, 70, 226, 231, 298
			D05312
			D05462
		[6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D	D01385	Ibudilast	[2] 2, 13
		[4] PDE4A, PDE4B, PDE4C, PDE4D	D01783	Rolipram	[2] 8, 13
118	mTOR signaling pathway 3 genes, 3 drugs (DrugBank), 46 diseases shown	[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[2] PRKAA1, PRKAA2	D00944	Metformin	[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299
			D04966
119	Natural killer cell mediated cytotoxicity 13 genes, 6 drugs (DrugBank), 34 diseases shown	[5] HLA-A, HLA-B, HLA-C, HLA-E, HLA-G	D04318	Glatiramer	[4] 2, 13, 96, 156
		[2] IFNAR1, IFNAR2	D04554	Interferon beta-1a	[5] 13, 14, 26, 96, 97
			D00746	Interferon beta-1b	[1] 13
			D10483	Peginterferon beta-1a	[1] 13
		[1] ITGAL	D03959	Efalizumab	[9] 11, 13, 37, 46, 49, 53, 61, 95, 96
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
120	Necroptosis 2 genes, 3 drugs (DrugBank), 5 diseases shown	[2] IFNAR1, IFNAR2	D04554	Interferon beta-1a	[5] 13, 14, 26, 96, 97
			D00746	Interferon beta-1b	[1] 13
			D10483	Peginterferon beta-1a	[1] 13
121	Neuroactive ligand-receptor interaction 79 genes, 58 drugs (DrugBank), 108 diseases shown	[4] ADORA1, ADORA2A, ADORA2B, ADORA3	D00045	Adenosine	[5] 13, 46, 53, 58, 65
		[1] ADRA1A	D01692	Alfuzosin	[1] 13
			D07124
			D01965	Silodosin	[2] 6, 13
		[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3	D00095	Epinephrine	[9] 6, 13, 46, 86, 96, 168, 226, 231, 256
			D00996
			D02149
		[3] ADRA2A, ADRA2B, ADRA2C	D04375	Guanabenz	[2] 2, 13
			D00776	Tizanidine	[1] 13
			D08611
		[1] ADRB2	D08092	Isoxsuprine	[1] 13
			D02147	Salbutamol	[13] 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299
		[1] ADRB3	D09535	Mirabegron	[3] 6, 13, 226
		[1] AGTR1	D00357	Losartan	[18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
			D08146
		[1] C5	D03940	Eculizumab	[7] 11, 13, 14, 62, 109, 222, 223
		[1] CHRM3	D01699	Darifenacin	[2] 6, 13
			D03654
		[2] CNR1, CNR2	D10915	Cannabidiol	[14] 2, 6, 13, 46, 95, 96, 97, 140, 144, 145, 157, 158, 193, 271
			D00306	Dronabinol	[5] 2, 13, 46, 271, 298
			D05099	Nabilone	[2] 6, 13
		[1] CYSLTR1	D00529	Montelukast	[5] 13, 46, 85, 98, 228
			D08229
		[2] CYSLTR1, PTGIR	D01385	Ibudilast	[2] 2, 13
		[1] DRD2	D01745	Domperidone	[5] 6, 13, 17, 51, 230
			D07868
		[2] DRD2, HTR2A	D00458	Quetiapine	[2] 6, 13
			D08456
		[2] EDNRA, EDNRB	D01227	Bosentan	[10] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211
			D07538
		[2] GABBR1, GABBR2	D09791	Arbaclofen	[2] 13, 206
			D08861	Arbaclofen Placarbil	[1] 13
			D00241	Baclofen	[5] 2, 10, 13, 18, 149
		[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ	D02624	Eszopiclone	[3] 6, 13, 46
			D00697	Flumazenil	[5] 6, 13, 17, 18, 206
			D00550	Midazolam	[10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298
			D00696
			D05028
		[1] GHR	D02691	Somatotropin	[18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299
		[1] GHRHR	D08523	Somatorelin	[2] 13, 78
		[14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D	D00775	Riluzole	[7] 2, 3, 5, 8, 13, 17, 206
		[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D	D00777	Amantadine	[4] 6, 8, 13, 127
			D07441
			D00848	Dextromethorphan	[9] 2, 6, 8, 13, 46, 78, 96, 97, 156
			D03742
			D03744
			D00711	Ketamine	[6] 6, 13, 70, 113, 156, 215
			D08098
			D04905	Memantine	[7] 2, 6, 8, 13, 49, 127, 205
			D08174
		[2] HCRTR1, HCRTR2	D10082	Suvorexant	[3] 5, 6, 13
		[1] HRH1	D00664	Cetirizine	[2] 13, 35
			D07662
			D00666	Clemastine	[1] 13
			D03535
			D07803	Dexchlorpheniramine	[1] 13
			D00364	Loratadine	[3] 6, 13, 46
		[1] HRH2	D00422	Ranitidine	[2] 13, 65
			D00673
		[2] HTR2A, HTR4	D00274	Cisapride	[1] 13
			D02092
		[1] HTR4	D09205	Prucalopride	[3] 13, 51, 96
		[1] MC2R	D00146	Corticotropin	[12] 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222
		[2] MTNR1A, MTNR1B	D08170	Melatonin	[8] 6, 13, 46, 49, 90, 97, 144, 202
[1] NR3C1	D00292	Dexamethasone	[20] 13, 16, 28, 35, 46, 53, 63, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 222, 296, 299
	D00975
	D01510
	D01615
	D01632
	D01948
	D02174
	D02591
	D02592
	D00407	Methylprednisolone	[36] 2, 13, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 145, 164, 220, 222, 224, 271, 283, 284, 285, 296
	D00751
	D00979
	D05000
	D05001
	D05002
	D05000	Methylprednisolone hemisuccinate	[2] 13, 97
	D00472	Prednisolone	[38] 11, 13, 25, 26, 35, 38, 39, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300
	D00980
	D00981
	D00982
	D01239
	D01998
	D02156
	D03301
	D00473	Prednisone	[44] 2, 11, 13, 14, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 95, 96, 97, 113, 145, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331
	D00385	Triamcinolone	[18] 6, 10, 13, 35, 40, 41, 42, 43, 44, 45, 46, 56, 70, 90, 96, 97, 226, 298
	D00983
	D00984
	D00985
	D06216
[3] OPRD1, OPRK1, OPRM1	D00729	Loperamide	[2] 13, 97
	D07113
	D08144
	D02095	Naltrexone	[11] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97
	D05113
	D03783	Oxycodone	[7] 6, 13, 46, 70, 226, 231, 298
	D05312
	D05462
[2] PTGDR, TBXA2R	D01128	Ramatroban	[1] 13
[1] S1PR1	D10001	Fingolimod	[4] 2, 13, 14, 156
	D11215	Ponesimod	[1] 13
[5] S1PR1, S1PR2, S1PR3, S1PR4, S1PR5	D10968	Ozanimod	[3] 13, 96, 97
[2] S1PR1, S1PR5	D11460	Siponimod	[2] 13, 50
[2] THRA, THRB	D01011	Liothyronine	[3] 13, 78, 212
	D08128
122	Neurotrophin signaling pathway 2 genes, 2 drugs (DrugBank), 11 diseases shown	[1] ABL1	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
		[1] PSEN1	D09010	Tarenflurbil	[1] 13
123	NF-kappa B signaling pathway 4 genes, 9 drugs (DrugBank), 32 diseases shown	[1] IL1R1	D02934	Anakinra	[17] 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299
		[1] LTB	D08866	Baminercept	[4] 13, 46, 53, 97
		[1] PTGS2	D00217	Acetaminophen	[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271
			D00109	Acetylsalicylic acid	[10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231
			D00903	Diclofenac	[4] 13, 34, 46, 271
			D00904
			D07816
			D00330	Flurbiprofen	[2] 13, 46
			D01475
			D02290
			D00126	Ibuprofen	[6] 13, 46, 65, 113, 271, 299
			D01122
			D04490
			D06606
			D00118	Naproxen	[3] 13, 46, 271
		[1] TNFSF13B	D09704	Atacicept	[4] 13, 46, 49, 66
124	Nicotine addiction 25 genes, 8 drugs (DrugBank), 22 diseases shown	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ	D02624	Eszopiclone	[3] 6, 13, 46
			D00697	Flumazenil	[5] 6, 13, 17, 18, 206
			D00550	Midazolam	[10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298
			D00696
			D05028
		[9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D	D00775	Riluzole	[7] 2, 3, 5, 8, 13, 17, 206
		[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D	D00777	Amantadine	[4] 6, 8, 13, 127
			D07441
			D00848	Dextromethorphan	[9] 2, 6, 8, 13, 46, 78, 96, 97, 156
			D03742
			D03744
			D00711	Ketamine	[6] 6, 13, 70, 113, 156, 215
			D08098
			D04905	Memantine	[7] 2, 6, 8, 13, 49, 127, 205
			D08174
125	Nitrogen metabolism 13 genes, 1 drug (DrugBank), 6 diseases shown	[13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9	D00218	Acetazolamide	[6] 13, 90, 115, 155, 225, 230
			D01196
126	NOD-like receptor signaling pathway 2 genes, 3 drugs (DrugBank), 5 diseases shown	[2] IFNAR1, IFNAR2	D04554	Interferon beta-1a	[5] 13, 14, 26, 96, 97
			D00746	Interferon beta-1b	[1] 13
			D10483	Peginterferon beta-1a	[1] 13
127	Non-alcoholic fatty liver disease (NAFLD) 4 genes, 3 drugs (DrugBank), 30 diseases shown	[1] IL6R	D02596	Tocilizumab	[16] 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331
		[2] PRKAA1, PRKAA2	D00944	Metformin	[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299
			D04966
		[1] RXRA	D03106	Bexarotene	[2] 13, 75
128	Non-small cell lung cancer 4 genes, 2 drugs (DrugBank), 5 diseases shown	[1] RARB	D06543	Vitamin A	[4] 13, 49, 53, 90
		[3] RXRA, RXRB, RXRG	D03106	Bexarotene	[2] 13, 75
129	Notch signaling pathway 4 genes, 1 drug (DrugBank), 1 disease shown	[4] APH1A, NCSTN, PSEN1, PSENEN	D09010	Tarenflurbil	[1] 13
130	One carbon pool by folate 2 genes, 1 drug (DrugBank), 33 diseases shown	[2] DHFR, DHFR2	D00142	Methotrexate	[33] 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331
			D02115
131	Oocyte meiosis 7 genes, 8 drugs (DrugBank), 34 diseases shown	[1] AR	D00075	Testosterone	[7] 1, 2, 3, 13, 78, 113, 265
			D00957
			D00958
			D00959
			D06085
			D06087
			D06087	Testosterone undecanoate	[1] 13
		[1] PGR	D01217	Dydrogesterone	[1] 13
			D00950	Levonorgestrel	[1] 13
			D07222	Nomegestrol	[1] 13
			D08281	Nomegestrol acetate	[1] 13
			D00182	Norethisterone	[4] 13, 46, 49, 299
			D00953
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
132	Osteoclast differentiation 9 genes, 6 drugs (DrugBank), 49 diseases shown	[2] IFNAR1, IFNAR2	D04554	Interferon beta-1a	[5] 13, 14, 26, 96, 97
			D00746	Interferon beta-1b	[1] 13
			D10483	Peginterferon beta-1a	[1] 13
		[1] IL1R1	D02934	Anakinra	[17] 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299
		[1] PPARG	D00945	Pioglitazone	[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
			D08378
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
133	Ovarian steroidogenesis 2 genes, 7 drugs (DrugBank), 20 diseases shown	[1] CYP17A1	D00351	Ketoconazole	[3] 8, 13, 75
		[1] PTGS2	D00217	Acetaminophen	[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271
			D00109	Acetylsalicylic acid	[10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231
			D00903	Diclofenac	[4] 13, 34, 46, 271
			D00904
			D07816
			D00330	Flurbiprofen	[2] 13, 46
			D01475
			D02290
			D00126	Ibuprofen	[6] 13, 46, 65, 113, 271, 299
			D01122
			D04490
			D06606
			D00118	Naproxen	[3] 13, 46, 271
134	Oxidative phosphorylation 2 genes, 2 drugs (DrugBank), 16 diseases shown	[2] ATP4A, ATP4B	D00455	Omeprazole	[15] 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
			D01207
			D05259
			D05261
			D02593	Pantoprazole	[2] 13, 65
			D05353
135	Oxytocin signaling pathway 12 genes, 10 drugs (DrugBank), 50 diseases shown	[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4	D00332	Gabapentin	[7] 6, 13, 19, 70, 97, 226, 298
			D02716	Pregabalin	[5] 13, 36, 46, 70, 298
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
		[2] PRKAA1, PRKAA2	D00944	Metformin	[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299
			D04966
		[1] PTGS2	D00217	Acetaminophen	[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271
			D00109	Acetylsalicylic acid	[10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231
			D00903	Diclofenac	[4] 13, 34, 46, 271
			D00904
			D07816
			D00330	Flurbiprofen	[2] 13, 46
			D01475
			D02290
			D00126	Ibuprofen	[6] 13, 46, 65, 113, 271, 299
			D01122
			D04490
			D06606
			D00118	Naproxen	[3] 13, 46, 271
136	p53 signaling pathway 1 gene, 1 drug (DrugBank), 8 diseases shown	[1] RRM2	D00341	Hydroxyurea	[8] 3, 13, 19, 20, 65, 85, 86, 284
137	Pancreatic cancer 2 genes, 3 drugs (DrugBank), 38 diseases shown	[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[1] VEGFA	D06409	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331
138	Pancreatic secretion 2 genes, 2 drugs (DrugBank), 7 diseases shown	[1] CA2	D00218	Acetazolamide	[6] 13, 90, 115, 155, 225, 230
			D01196
		[1] CHRM3	D01699	Darifenacin	[2] 6, 13
			D03654
139	Parathyroid hormone synthesis, secretion and action 8 genes, 4 drugs (DrugBank), 18 diseases shown	[4] PDE4A, PDE4B, PDE4C, PDE4D	D01385	Ibudilast	[2] 2, 13
			D01783	Rolipram	[2] 8, 13
		[3] RXRA, RXRB, RXRG	D03106	Bexarotene	[2] 13, 75
		[1] VDR	D00188	Cholecalciferol	[15] 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299
140	Parkinson disease 3 genes, 6 drugs (DrugBank), 14 diseases shown	[1] ADORA2A	D00045	Adenosine	[5] 13, 46, 53, 58, 65
		[1] DRD2	D01745	Domperidone	[5] 6, 13, 17, 51, 230
			D07868
			D00458	Quetiapine	[2] 6, 13
			D08456
		[1] SLC6A3	D03215	Armodafinil	[3] 6, 13, 84
			D08130	Lisdexamfetamine	[1] 13
			D01296	Methylphenidate	[7] 6, 13, 34, 84, 113, 179, 206
			D04999
141	Pathogenic Escherichia coli infection 2 genes, 2 drugs (DrugBank), 25 diseases shown	[1] ABL1	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
		[1] IL1R1	D02934	Anakinra	[17] 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299
142	Pathways in cancer 30 genes, 32 drugs (DrugBank), 95 diseases shown	[3] ABL1, KIT, PDGFRA	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
		[1] AGTR1	D00357	Losartan	[18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
			D08146
		[1] AR	D00075	Testosterone	[7] 1, 2, 3, 13, 78, 113, 265
			D00957
			D00958
			D00959
			D06085
			D06087
			D06087	Testosterone undecanoate	[1] 13
		[1] CSF3R	D03235	Filgrastim	[28] 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331
		[2] EDNRA, EDNRB	D01227	Bosentan	[10] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211
			D07538
		[1] EPOR	D03231	Erythropoietin	[9] 2, 6, 13, 22, 46, 47, 70, 95, 96
		[1] ESR1	D00554	Ethinylestradiol	[4] 13, 46, 49, 299
		[2] ESR1, ESR2	D00105	Estradiol	[5] 13, 46, 49, 226, 299
			D01413
			D01617
			D01953
			D04061
			D04063
			D04064
			D04065
			D00185	Estriol	[2] 13, 227
			D01986
		[1] FGFR2	D05338	Palifermin	[4] 13, 38, 39, 65
		[2] IFNAR1, IFNAR2	D04554	Interferon beta-1a	[5] 13, 14, 26, 96, 97
			D00746	Interferon beta-1b	[1] 13
			D10483	Peginterferon beta-1a	[1] 13
		[3] IL12A, IL12B, IL23A	D09214	Ustekinumab	[16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271
		[1] IL2RA	D03639	Daclizumab	[7] 13, 56, 60, 65, 97, 283, 284
		[1] IL6R	D02596	Tocilizumab	[16] 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331
		[1] KEAP1	D03846	Dimethyl fumarate	[5] 13, 46, 49, 51, 86
		[1] KIT	D10229	Masitinib	[6] 2, 5, 6, 13, 46, 96
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[1] NQO1	D00564	Warfarin	[10] 6, 8, 13, 19, 46, 49, 66, 85, 88, 96
			D01280
			D08682
		[1] PPARG	D00945	Pioglitazone	[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
			D08378
		[1] PTGS2	D00217	Acetaminophen	[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271
			D00109	Acetylsalicylic acid	[10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231
			D00903	Diclofenac	[4] 13, 34, 46, 271
			D00904
			D07816
			D00330	Flurbiprofen	[2] 13, 46
			D01475
			D02290
			D00126	Ibuprofen	[6] 13, 46, 65, 113, 271, 299
			D01122
			D04490
			D06606
			D00118	Naproxen	[3] 13, 46, 271
		[2] RARA, RARB	D06543	Vitamin A	[4] 13, 49, 53, 90
		[3] RXRA, RXRB, RXRG	D03106	Bexarotene	[2] 13, 75
		[1] VEGFA	D06409	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331
143	PD-L1 expression and PD-1 checkpoint pathway in cancer 7 genes, 4 drugs (DrugBank), 51 diseases shown	[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[1] PDCD1	D10316	Nivolumab	[10] 13, 26, 41, 46, 49, 50, 51, 53, 96, 97
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
144	Peroxisome 1 gene, 1 drug (DrugBank), 3 diseases shown	[1] XDH	D01206	Febuxostat	[3] 2, 6, 13
145	Pertussis 4 genes, 2 drugs (DrugBank), 22 diseases shown	[1] C5	D03940	Eculizumab	[7] 11, 13, 14, 62, 109, 222, 223
		[3] IL12A, IL12B, IL23A	D09214	Ustekinumab	[16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271
146	Phagosome 20 genes, 1 drug (DrugBank), 4 diseases shown	[20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G	D04318	Glatiramer	[4] 2, 13, 96, 156
147	Phenylalanine metabolism 1 gene, 1 drug (DrugBank), 8 diseases shown	[1] DDC	D00558	Carbidopa	[8] 2, 4, 6, 13, 17, 90, 164, 201
148	Phospholipase D signaling pathway 4 genes, 5 drugs (DrugBank), 50 diseases shown	[1] AGTR1	D00357	Losartan	[18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
			D08146
		[1] KIT	D10229	Masitinib	[6] 2, 5, 6, 13, 46, 96
		[2] KIT, PDGFRA	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
149	PI3K-Akt signaling pathway 16 genes, 18 drugs (DrugBank), 87 diseases shown	[1] CSF3R	D03235	Filgrastim	[28] 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331
		[1] EPOR	D03231	Erythropoietin	[9] 2, 6, 13, 22, 46, 47, 70, 95, 96
		[1] FGFR2	D05338	Palifermin	[4] 13, 38, 39, 65
		[1] GHR	D02691	Somatotropin	[18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299
		[2] IFNAR1, IFNAR2	D04554	Interferon beta-1a	[5] 13, 14, 26, 96, 97
			D00746	Interferon beta-1b	[1] 13
			D10483	Peginterferon beta-1a	[1] 13
		[1] IL2RA	D03639	Daclizumab	[7] 13, 56, 60, 65, 97, 283, 284
		[1] IL6R	D02596	Tocilizumab	[16] 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331
		[1] ITGA4	D06590	Firategrast	[1] 13
			D06886	Natalizumab	[6] 13, 15, 25, 46, 63, 96
		[1] KIT	D10229	Masitinib	[6] 2, 5, 6, 13, 46, 96
		[2] KIT, PDGFRA	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[2] PRKAA1, PRKAA2	D00944	Metformin	[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299
			D04966
		[1] RXRA	D03106	Bexarotene	[2] 13, 75
		[1] VEGFA	D06409	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331
150	Platelet activation 3 genes, 8 drugs (DrugBank), 19 diseases shown	[1] PTGIR	D01385	Ibudilast	[2] 2, 13
		[1] PTGS1	D00217	Acetaminophen	[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271
			D00109	Acetylsalicylic acid	[10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231
			D00903	Diclofenac	[4] 13, 34, 46, 271
			D00904
			D07816
			D00330	Flurbiprofen	[2] 13, 46
			D01475
			D02290
			D00126	Ibuprofen	[6] 13, 46, 65, 113, 271, 299
			D01122
			D04490
			D06606
			D00118	Naproxen	[3] 13, 46, 271
		[1] TBXA2R	D01128	Ramatroban	[1] 13
151	Platinum drug resistance 2 genes, 4 drugs (DrugBank), 11 diseases shown	[2] TOP2A, TOP2B	D03730	Dexrazoxane	[1] 13
			D00125	Etoposide	[11] 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331
			D04107
			D02166	Mitoxantrone	[1] 13
			D08224
			D05522	Pixantrone	[2] 11, 13
152	PPAR signaling pathway 4 genes, 2 drugs (DrugBank), 18 diseases shown	[1] PPARG	D00945	Pioglitazone	[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
			D08378
		[3] RXRA, RXRB, RXRG	D03106	Bexarotene	[2] 13, 75
153	Prion diseases 1 gene, 1 drug (DrugBank), 7 diseases shown	[1] C5	D03940	Eculizumab	[7] 11, 13, 14, 62, 109, 222, 223
154	Progesterone-mediated oocyte maturation 2 genes, 6 drugs (DrugBank), 5 diseases shown	[1] PDE3B	D01385	Ibudilast	[2] 2, 13
		[1] PGR	D01217	Dydrogesterone	[1] 13
			D00950	Levonorgestrel	[1] 13
			D07222	Nomegestrol	[1] 13
			D08281	Nomegestrol acetate	[1] 13
			D00182	Norethisterone	[4] 13, 46, 49, 299
			D00953
155	Prolactin signaling pathway 3 genes, 4 drugs (DrugBank), 8 diseases shown	[1] CYP17A1	D00351	Ketoconazole	[3] 8, 13, 75
		[1] ESR1	D00554	Ethinylestradiol	[4] 13, 46, 49, 299
		[2] ESR1, ESR2	D00105	Estradiol	[5] 13, 46, 49, 226, 299
			D01413
			D01617
			D01953
			D04061
			D04063
			D04064
			D04065
			D00185	Estriol	[2] 13, 227
			D01986
156	Prostate cancer 5 genes, 7 drugs (DrugBank), 56 diseases shown	[1] AR	D00075	Testosterone	[7] 1, 2, 3, 13, 78, 113, 265
			D00957
			D00958
			D00959
			D06085
			D06087
			D06087	Testosterone undecanoate	[1] 13
		[1] FGFR2	D05338	Palifermin	[4] 13, 38, 39, 65
		[1] IL1R2	D02934	Anakinra	[17] 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[1] PDGFRA	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
157	Proteasome 1 gene, 1 drug (DrugBank), 4 diseases shown	[1] PSMB5	D10130	Ixazomib	[4] 13, 16, 28, 61
158	Proteoglycans in cancer 4 genes, 7 drugs (DrugBank), 51 diseases shown	[1] ESR1	D00105	Estradiol	[5] 13, 46, 49, 226, 299
			D01413
			D01617
			D01953
			D04061
			D04063
			D04064
			D04065
			D00185	Estriol	[2] 13, 227
			D01986
			D00554	Ethinylestradiol	[4] 13, 46, 49, 299
		[1] IL12B	D09214	Ustekinumab	[16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[1] VEGFA	D06409	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331
159	Proximal tubule bicarbonate reclamation 2 genes, 1 drug (DrugBank), 6 diseases shown	[2] CA2, CA4	D00218	Acetazolamide	[6] 13, 90, 115, 155, 225, 230
			D01196
160	Purine metabolism 12 genes, 9 drugs (DrugBank), 43 diseases shown	[2] IMPDH1, IMPDH2	D00752	Mycophenolate mofetil	[32] 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
			D05094
			D05095
			D05096	Mycophenolic acid	[34] 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
		[6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D	D01385	Ibudilast	[2] 2, 13
		[4] PDE4A, PDE4B, PDE4C, PDE4D	D01783	Rolipram	[2] 8, 13
		[1] PDE5A	D02731	Vardenafil	[3] 13, 86, 299
			D03260
			D08668
		[1] RRM1	D01370	Cladribine	[2] 13, 94
			D01907	Fludarabine	[17] 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326
			D07966
		[1] RRM2	D00341	Hydroxyurea	[8] 3, 13, 19, 20, 65, 85, 86, 284
		[1] XDH	D01206	Febuxostat	[3] 2, 6, 13
161	Pyrimidine metabolism 3 genes, 4 drugs (DrugBank), 23 diseases shown	[1] DHODH	D10172	Teriflunomide	[2] 13, 25
		[1] RRM1	D01370	Cladribine	[2] 13, 94
			D01907	Fludarabine	[17] 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326
			D07966
		[1] RRM2	D00341	Hydroxyurea	[8] 3, 13, 19, 20, 65, 85, 86, 284
162	Rap1 signaling pathway 12 genes, 16 drugs (DrugBank), 49 diseases shown	[2] ADORA2A, ADORA2B	D00045	Adenosine	[5] 13, 46, 53, 58, 65
		[1] CNR1	D10915	Cannabidiol	[14] 2, 6, 13, 46, 95, 96, 97, 140, 144, 145, 157, 158, 193, 271
			D00306	Dronabinol	[5] 2, 13, 46, 271, 298
			D05099	Nabilone	[2] 6, 13
		[1] DRD2	D01745	Domperidone	[5] 6, 13, 17, 51, 230
			D07868
			D00458	Quetiapine	[2] 6, 13
			D08456
		[1] FGFR2	D05338	Palifermin	[4] 13, 38, 39, 65
		[3] GRIN1, GRIN2A, GRIN2B	D00777	Amantadine	[4] 6, 8, 13, 127
			D07441
			D00848	Dextromethorphan	[9] 2, 6, 8, 13, 46, 78, 96, 97, 156
			D03742
			D03744
			D00711	Ketamine	[6] 6, 13, 70, 113, 156, 215
			D08098
			D04905	Memantine	[7] 2, 6, 8, 13, 49, 127, 205
			D08174
			D00775	Riluzole	[7] 2, 3, 5, 8, 13, 17, 206
		[1] ITGAL	D03959	Efalizumab	[9] 11, 13, 37, 46, 49, 53, 61, 95, 96
		[1] KIT	D10229	Masitinib	[6] 2, 5, 6, 13, 46, 96
		[2] KIT, PDGFRA	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
		[1] VEGFA	D06409	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331
163	Ras signaling pathway 8 genes, 9 drugs (DrugBank), 34 diseases shown	[3] ABL1, KIT, PDGFRA	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
		[1] FGFR2	D05338	Palifermin	[4] 13, 38, 39, 65
		[3] GRIN1, GRIN2A, GRIN2B	D00777	Amantadine	[4] 6, 8, 13, 127
			D07441
			D00848	Dextromethorphan	[9] 2, 6, 8, 13, 46, 78, 96, 97, 156
			D03742
			D03744
			D00711	Ketamine	[6] 6, 13, 70, 113, 156, 215
			D08098
			D04905	Memantine	[7] 2, 6, 8, 13, 49, 127, 205
			D08174
			D00775	Riluzole	[7] 2, 3, 5, 8, 13, 17, 206
		[1] KIT	D10229	Masitinib	[6] 2, 5, 6, 13, 46, 96
		[1] VEGFA	D06409	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331
164	Regulation of actin cytoskeleton 5 genes, 6 drugs (DrugBank), 25 diseases shown	[1] CHRM3	D01699	Darifenacin	[2] 6, 13
			D03654
		[1] FGFR2	D05338	Palifermin	[4] 13, 38, 39, 65
		[1] ITGA4	D06590	Firategrast	[1] 13
			D06886	Natalizumab	[6] 13, 15, 25, 46, 63, 96
		[1] ITGAL	D03959	Efalizumab	[9] 11, 13, 37, 46, 49, 53, 61, 95, 96
		[1] PDGFRA	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
165	Regulation of lipolysis in adipocytes 7 genes, 12 drugs (DrugBank), 29 diseases shown	[1] ADORA1	D00045	Adenosine	[5] 13, 46, 53, 58, 65
		[3] ADRB1, ADRB2, ADRB3	D00095	Epinephrine	[9] 6, 13, 46, 86, 96, 168, 226, 231, 256
			D00996
			D02149
		[1] ADRB2	D08092	Isoxsuprine	[1] 13
			D02147	Salbutamol	[13] 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299
		[1] ADRB3	D09535	Mirabegron	[3] 6, 13, 226
		[1] PDE3B	D01385	Ibudilast	[2] 2, 13
		[2] PTGS1, PTGS2	D00217	Acetaminophen	[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271
			D00109	Acetylsalicylic acid	[10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231
			D00903	Diclofenac	[4] 13, 34, 46, 271
			D00904
			D07816
			D00330	Flurbiprofen	[2] 13, 46
			D01475
			D02290
			D00126	Ibuprofen	[6] 13, 46, 65, 113, 271, 299
			D01122
			D04490
			D06606
			D00118	Naproxen	[3] 13, 46, 271
166	Relaxin signaling pathway 2 genes, 2 drugs (DrugBank), 16 diseases shown	[1] EDNRB	D01227	Bosentan	[10] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211
			D07538
		[1] VEGFA	D06409	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331
167	Renal cell carcinoma 1 gene, 1 drug (DrugBank), 9 diseases shown	[1] VEGFA	D06409	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331
168	Renin secretion 13 genes, 9 drugs (DrugBank), 51 diseases shown	[1] ADORA1	D00045	Adenosine	[5] 13, 46, 53, 58, 65
		[3] ADRB1, ADRB2, ADRB3	D00095	Epinephrine	[9] 6, 13, 46, 86, 96, 168, 226, 231, 256
			D00996
			D02149
		[1] ADRB2	D08092	Isoxsuprine	[1] 13
			D02147	Salbutamol	[13] 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299
		[1] ADRB3	D09535	Mirabegron	[3] 6, 13, 226
		[1] AGTR1	D00357	Losartan	[18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
			D08146
		[1] EDNRA	D01227	Bosentan	[10] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211
			D07538
		[2] PDE3A, PDE3B	D01385	Ibudilast	[2] 2, 13
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
169	Renin-angiotensin system 1 gene, 1 drug (DrugBank), 18 diseases shown	[1] AGTR1	D00357	Losartan	[18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
			D08146
170	Retrograde endocannabinoid signaling 22 genes, 13 drugs (DrugBank), 33 diseases shown	[1] CNR1	D10915	Cannabidiol	[14] 2, 6, 13, 46, 95, 96, 97, 140, 144, 145, 157, 158, 193, 271
			D00306	Dronabinol	[5] 2, 13, 46, 271, 298
			D05099	Nabilone	[2] 6, 13
		[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ	D02624	Eszopiclone	[3] 6, 13, 46
			D00697	Flumazenil	[5] 6, 13, 17, 18, 206
			D00550	Midazolam	[10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298
			D00696
			D05028
		[4] GRIA1, GRIA2, GRIA3, GRIA4	D00775	Riluzole	[7] 2, 3, 5, 8, 13, 17, 206
		[1] PTGS2	D00217	Acetaminophen	[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271
			D00109	Acetylsalicylic acid	[10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231
			D00903	Diclofenac	[4] 13, 34, 46, 271
			D00904
			D07816
			D00330	Flurbiprofen	[2] 13, 46
			D01475
			D02290
			D00126	Ibuprofen	[6] 13, 46, 65, 113, 271, 299
			D01122
			D04490
			D06606
			D00118	Naproxen	[3] 13, 46, 271
171	Rheumatoid arthritis 23 genes, 8 drugs (DrugBank), 42 diseases shown	[2] CD80, CD86	D03203	Abatacept	[24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300
		[14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5	D04318	Glatiramer	[4] 2, 13, 96, 156
		[1] IL17A	D09967	Secukinumab	[7] 13, 37, 41, 46, 160, 269, 271
		[1] IL23A	D09214	Ustekinumab	[16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271
		[1] ITGAL	D03959	Efalizumab	[9] 11, 13, 37, 46, 49, 53, 61, 95, 96
		[1] LTB	D08866	Baminercept	[4] 13, 46, 53, 97
		[2] TNFSF13, TNFSF13B	D09704	Atacicept	[4] 13, 46, 49, 66
		[1] VEGFA	D06409	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331
172	RIG-I-like receptor signaling pathway 2 genes, 1 drug (DrugBank), 16 diseases shown	[2] IL12A, IL12B	D09214	Ustekinumab	[16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271
173	Salivary secretion 7 genes, 7 drugs (DrugBank), 18 diseases shown	[1] ADRA1A	D01692	Alfuzosin	[1] 13
			D07124
			D01965	Silodosin	[2] 6, 13
		[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3	D00095	Epinephrine	[9] 6, 13, 46, 86, 96, 168, 226, 231, 256
			D00996
			D02149
		[1] ADRB2	D08092	Isoxsuprine	[1] 13
			D02147	Salbutamol	[13] 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299
		[1] ADRB3	D09535	Mirabegron	[3] 6, 13, 226
		[1] CHRM3	D01699	Darifenacin	[2] 6, 13
			D03654
174	Serotonergic synapse 11 genes, 19 drugs (DrugBank), 31 diseases shown	[1] DDC	D00558	Carbidopa	[8] 2, 4, 6, 13, 17, 90, 164, 201
		[3] GABRB1, GABRB2, GABRB3	D02624	Eszopiclone	[3] 6, 13, 46
			D00697	Flumazenil	[5] 6, 13, 17, 18, 206
			D00550	Midazolam	[10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298
			D00696
			D05028
		[1] HTR2A	D00458	Quetiapine	[2] 6, 13
			D08456
		[3] HTR2A, HTR3A, HTR4	D00274	Cisapride	[1] 13
			D02092
		[1] HTR4	D09205	Prucalopride	[3] 13, 51, 96
		[1] KCND2	D04127	Dalfampridine	[3] 3, 4, 13
		[2] PTGS1, PTGS2	D00217	Acetaminophen	[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271
			D00109	Acetylsalicylic acid	[10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231
			D00903	Diclofenac	[4] 13, 34, 46, 271
			D00904
			D07816
			D00330	Flurbiprofen	[2] 13, 46
			D01475
			D02290
			D00126	Ibuprofen	[6] 13, 46, 65, 113, 271, 299
			D01122
			D04490
			D06606
			D00118	Naproxen	[3] 13, 46, 271
		[1] SLC6A4	D01179	Duloxetine	[3] 6, 13, 49
			D07880
			D02567	Escitalopram	[3] 2, 6, 13
			D07704
			D07913
			D00326	Fluoxetine	[6] 13, 17, 78, 86, 179, 206
			D00823
			D02260	Paroxetine	[3] 6, 13, 46
			D02362
			D05374
			D05375
			D00821	Venlafaxine	[3] 6, 13, 46
			D08670
175	Shigellosis 3 genes, 4 drugs (DrugBank), 49 diseases shown	[1] ABL1	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
		[1] IL1R1	D02934	Anakinra	[17] 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
176	Signaling pathways regulating pluripotency of stem cells 1 gene, 1 drug (DrugBank), 4 diseases shown	[1] FGFR2	D05338	Palifermin	[4] 13, 38, 39, 65
177	Small cell lung cancer 5 genes, 8 drugs (DrugBank), 21 diseases shown	[1] PTGS2	D00217	Acetaminophen	[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271
			D00109	Acetylsalicylic acid	[10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231
			D00903	Diclofenac	[4] 13, 34, 46, 271
			D00904
			D07816
			D00330	Flurbiprofen	[2] 13, 46
			D01475
			D02290
			D00126	Ibuprofen	[6] 13, 46, 65, 113, 271, 299
			D01122
			D04490
			D06606
			D00118	Naproxen	[3] 13, 46, 271
		[1] RARB	D06543	Vitamin A	[4] 13, 49, 53, 90
		[3] RXRA, RXRB, RXRG	D03106	Bexarotene	[2] 13, 75
178	Sphingolipid signaling pathway 8 genes, 8 drugs (DrugBank), 23 diseases shown	[2] ADORA1, ADORA3	D00045	Adenosine	[5] 13, 46, 53, 58, 65
		[1] OPRD1	D00729	Loperamide	[2] 13, 97
			D07113
			D08144
			D02095	Naltrexone	[11] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97
			D05113
			D03783	Oxycodone	[7] 6, 13, 46, 70, 226, 231, 298
			D05312
			D05462
		[1] S1PR1	D10001	Fingolimod	[4] 2, 13, 14, 156
			D11215	Ponesimod	[1] 13
		[5] S1PR1, S1PR2, S1PR3, S1PR4, S1PR5	D10968	Ozanimod	[3] 13, 96, 97
		[2] S1PR1, S1PR5	D11460	Siponimod	[2] 13, 50
179	Staphylococcus aureus infection 16 genes, 3 drugs (DrugBank), 16 diseases shown	[1] C5	D03940	Eculizumab	[7] 11, 13, 14, 62, 109, 222, 223
		[14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5	D04318	Glatiramer	[4] 2, 13, 96, 156
		[1] ITGAL	D03959	Efalizumab	[9] 11, 13, 37, 46, 49, 53, 61, 95, 96
180	Steroid hormone biosynthesis 1 gene, 1 drug (DrugBank), 3 diseases shown	[1] CYP17A1	D00351	Ketoconazole	[3] 8, 13, 75
181	Synaptic vesicle cycle 5 genes, 11 drugs (DrugBank), 25 diseases shown	[1] SLC6A1	D00332	Gabapentin	[7] 6, 13, 19, 70, 97, 226, 298
		[1] SLC6A2	D02574	Atomoxetine	[3] 6, 8, 13
			D07473
		[2] SLC6A2, SLC6A3	D08130	Lisdexamfetamine	[1] 13
			D01296	Methylphenidate	[7] 6, 13, 34, 84, 113, 179, 206
			D04999
		[2] SLC6A2, SLC6A4	D01179	Duloxetine	[3] 6, 13, 49
			D07880
			D00821	Venlafaxine	[3] 6, 13, 46
			D08670
		[1] SLC6A3	D03215	Armodafinil	[3] 6, 13, 84
		[1] SLC6A4	D02567	Escitalopram	[3] 2, 6, 13
			D07704
			D07913
			D00326	Fluoxetine	[6] 13, 17, 78, 86, 179, 206
			D00823
			D02260	Paroxetine	[3] 6, 13, 46
			D02362
			D05374
			D05375
		[1] SNAP25	D00783	Botulinum toxin type A	[13] 2, 5, 6, 7, 13, 15, 17, 36, 51, 70, 113, 149, 226
182	Systemic lupus erythematosus 20 genes, 9 drugs (DrugBank), 43 diseases shown	[1] C5	D03940	Eculizumab	[7] 11, 13, 14, 62, 109, 222, 223
		[2] CD80, CD86	D03203	Abatacept	[24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300
		[1] ELANE	D03788	Sivelestat	[3] 13, 85, 96
		[2] GRIN2A, GRIN2B	D00777	Amantadine	[4] 6, 8, 13, 127
			D07441
			D00848	Dextromethorphan	[9] 2, 6, 8, 13, 46, 78, 96, 97, 156
			D03742
			D03744
			D00711	Ketamine	[6] 6, 13, 70, 113, 156, 215
			D08098
			D04905	Memantine	[7] 2, 6, 8, 13, 49, 127, 205
			D08174
			D00775	Riluzole	[7] 2, 3, 5, 8, 13, 17, 206
		[14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5	D04318	Glatiramer	[4] 2, 13, 96, 156
183	T cell receptor signaling pathway 6 genes, 2 drugs (DrugBank), 32 diseases shown	[1] PDCD1	D10316	Nivolumab	[10] 13, 26, 41, 46, 49, 50, 51, 53, 96, 97
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
184	Taste transduction 16 genes, 14 drugs (DrugBank), 25 diseases shown	[1] CHRM3	D01699	Darifenacin	[2] 6, 13
			D03654
		[2] GABBR1, GABBR2	D09791	Arbaclofen	[2] 13, 206
			D08861	Arbaclofen Placarbil	[1] 13
			D00241	Baclofen	[5] 2, 10, 13, 18, 149
		[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6	D02624	Eszopiclone	[3] 6, 13, 46
			D00697	Flumazenil	[5] 6, 13, 17, 18, 206
			D00550	Midazolam	[10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298
			D00696
			D05028
		[1] HTR3A	D00274	Cisapride	[1] 13
			D02092
		[3] SCN2A, SCN3A, SCN9A	D00354	Lamotrigine	[3] 13, 34, 114
			D00358	Lidocaine	[10] 6, 13, 46, 84, 86, 97, 168, 226, 231, 256
			D02086
			D08127
			D00533	Oxcarbazepine	[1] 13
			D00512	Phenytoin	[1] 13
			D02103
			D00642	Quinidine	[3] 2, 8, 13
			D00643
			D02272
			D08458
		[3] SCNN1A, SCNN1B, SCNN1G	D00649	Amiloride	[3] 13, 225, 299
			D07447
185	Terpenoid backbone biosynthesis 2 genes, 4 drugs (DrugBank), 35 diseases shown	[1] FDPS	D01968	Zoledronic acid	[11] 6, 13, 46, 65, 93, 95, 96, 271, 274, 299, 333
			D06378
			D06379
			D08689
		[1] HMGCR	D00887	Atorvastatin	[17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299
			D07474
			D00893	Pravastatin	[9] 13, 46, 49, 67, 79, 96, 164, 265, 333
			D08410
			D00434	Simvastatin	[19] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310
186	TGF-beta signaling pathway 1 gene, 1 drug (DrugBank), 1 disease shown	[1] RGMA	D11355	Elezanumab	[1] 13
187	Th1 and Th2 cell differentiation 22 genes, 4 drugs (DrugBank), 39 diseases shown	[14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5	D04318	Glatiramer	[4] 2, 13, 96, 156
		[2] IL12A, IL12B	D09214	Ustekinumab	[16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271
		[1] IL2RA	D03639	Daclizumab	[7] 13, 56, 60, 65, 97, 283, 284
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
188	Th17 cell differentiation 29 genes, 11 drugs (DrugBank), 69 diseases shown	[14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5	D04318	Glatiramer	[4] 2, 13, 96, 156
		[1] IL17A	D09967	Secukinumab	[7] 13, 37, 41, 46, 160, 269, 271
		[1] IL1R1	D02934	Anakinra	[17] 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299
		[1] IL23A	D09214	Ustekinumab	[16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271
		[1] IL2RA	D03639	Daclizumab	[7] 13, 56, 60, 65, 97, 283, 284
		[1] IL6R	D02596	Tocilizumab	[16] 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
		[1] RARA	D06543	Vitamin A	[4] 13, 49, 53, 90
		[3] RXRA, RXRB, RXRG	D03106	Bexarotene	[2] 13, 75
189	Thermogenesis 6 genes, 9 drugs (DrugBank), 60 diseases shown	[1] ADRB3	D00095	Epinephrine	[9] 6, 13, 46, 86, 96, 168, 226, 231, 256
			D00996
			D02149
			D09535	Mirabegron	[3] 6, 13, 226
		[1] CNR1	D10915	Cannabidiol	[14] 2, 6, 13, 46, 95, 96, 97, 140, 144, 145, 157, 158, 193, 271
			D00306	Dronabinol	[5] 2, 13, 46, 271, 298
			D05099	Nabilone	[2] 6, 13
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[1] PPARG	D00945	Pioglitazone	[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
			D08378
		[2] PRKAA1, PRKAA2	D00944	Metformin	[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299
			D04966
190	Thyroid cancer 4 genes, 2 drugs (DrugBank), 18 diseases shown	[1] PPARG	D00945	Pioglitazone	[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
			D08378
		[3] RXRA, RXRB, RXRG	D03106	Bexarotene	[2] 13, 75
191	Thyroid hormone signaling pathway 7 genes, 7 drugs (DrugBank), 42 diseases shown	[1] ESR1	D00105	Estradiol	[5] 13, 46, 49, 226, 299
			D01413
			D01617
			D01953
			D04061
			D04063
			D04064
			D04065
			D00185	Estriol	[2] 13, 227
			D01986
			D00554	Ethinylestradiol	[4] 13, 46, 49, 299
		[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
		[3] RXRA, RXRB, RXRG	D03106	Bexarotene	[2] 13, 75
		[2] THRA, THRB	D01011	Liothyronine	[3] 13, 78, 212
			D08128
192	Tight junction 2 genes, 1 drug (DrugBank), 17 diseases shown	[2] PRKAA1, PRKAA2	D00944	Metformin	[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299
			D04966
193	TNF signaling pathway 1 gene, 6 drugs (DrugBank), 18 diseases shown	[1] PTGS2	D00217	Acetaminophen	[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271
			D00109	Acetylsalicylic acid	[10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231
			D00903	Diclofenac	[4] 13, 34, 46, 271
			D00904
			D07816
			D00330	Flurbiprofen	[2] 13, 46
			D01475
			D02290
			D00126	Ibuprofen	[6] 13, 46, 65, 113, 271, 299
			D01122
			D04490
			D06606
			D00118	Naproxen	[3] 13, 46, 271
194	Toll-like receptor signaling pathway 6 genes, 5 drugs (DrugBank), 30 diseases shown	[2] CD80, CD86	D03203	Abatacept	[24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300
		[2] IFNAR1, IFNAR2	D04554	Interferon beta-1a	[5] 13, 14, 26, 96, 97
			D00746	Interferon beta-1b	[1] 13
			D10483	Peginterferon beta-1a	[1] 13
		[2] IL12A, IL12B	D09214	Ustekinumab	[16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271
195	Toxoplasmosis 16 genes, 2 drugs (DrugBank), 18 diseases shown	[14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5	D04318	Glatiramer	[4] 2, 13, 96, 156
		[2] IL12A, IL12B	D09214	Ustekinumab	[16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271
196	Transcriptional misregulation in cancer 9 genes, 7 drugs (DrugBank), 48 diseases shown	[1] CD86	D03203	Abatacept	[24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300
		[1] ELANE	D03788	Sivelestat	[3] 13, 85, 96
		[1] GRIA3	D00775	Riluzole	[7] 2, 3, 5, 8, 13, 17, 206
		[1] IL1R2	D02934	Anakinra	[17] 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299
		[1] PPARG	D00945	Pioglitazone	[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
			D08378
		[1] RARA	D06543	Vitamin A	[4] 13, 49, 53, 90
		[3] RXRA, RXRB, RXRG	D03106	Bexarotene	[2] 13, 75
197	Tryptophan metabolism 1 gene, 1 drug (DrugBank), 8 diseases shown	[1] DDC	D00558	Carbidopa	[8] 2, 4, 6, 13, 17, 90, 164, 201
198	Tuberculosis 23 genes, 4 drugs (DrugBank), 44 diseases shown	[14] HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5	D04318	Glatiramer	[4] 2, 13, 96, 156
		[3] IL12A, IL12B, IL23A	D09214	Ustekinumab	[16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271
		[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
		[1] VDR	D00188	Cholecalciferol	[15] 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299
199	Type I diabetes mellitus 24 genes, 3 drugs (DrugBank), 30 diseases shown	[2] CD80, CD86	D03203	Abatacept	[24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300
		[20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G	D04318	Glatiramer	[4] 2, 13, 96, 156
		[2] IL12A, IL12B	D09214	Ustekinumab	[16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271
200	Type II diabetes mellitus 1 gene, 2 drugs (DrugBank), 36 diseases shown	[1] MTOR	D00753	Sirolimus	[36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
			D06068	Temsirolimus	[4] 13, 34, 89, 331
201	Tyrosine metabolism 1 gene, 1 drug (DrugBank), 8 diseases shown	[1] DDC	D00558	Carbidopa	[8] 2, 4, 6, 13, 17, 90, 164, 201
202	Ubiquinone and other terpenoid-quinone biosynthesis 2 genes, 1 drug (DrugBank), 10 diseases shown	[2] NQO1, VKORC1	D00564	Warfarin	[10] 6, 8, 13, 19, 46, 49, 66, 85, 88, 96
			D01280
			D08682
203	Ubiquitin mediated proteolysis 1 gene, 1 drug (DrugBank), 5 diseases shown	[1] KEAP1	D03846	Dimethyl fumarate	[5] 13, 46, 49, 51, 86
204	Vascular smooth muscle contraction 8 genes, 7 drugs (DrugBank), 34 diseases shown	[2] ADORA2A, ADORA2B	D00045	Adenosine	[5] 13, 46, 53, 58, 65
		[1] ADRA1A	D01692	Alfuzosin	[1] 13
			D07124
			D01965	Silodosin	[2] 6, 13
		[3] ADRA1A, ADRA1B, ADRA1D	D00095	Epinephrine	[9] 6, 13, 46, 86, 96, 168, 226, 231, 256
			D00996
			D02149
		[1] AGTR1	D00357	Losartan	[18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
			D08146
		[1] EDNRA	D01227	Bosentan	[10] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211
			D07538
		[1] PTGIR	D01385	Ibudilast	[2] 2, 13
205	VEGF signaling pathway 7 genes, 8 drugs (DrugBank), 44 diseases shown	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
		[1] PTGS2	D00217	Acetaminophen	[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271
			D00109	Acetylsalicylic acid	[10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231
			D00903	Diclofenac	[4] 13, 34, 46, 271
			D00904
			D07816
			D00330	Flurbiprofen	[2] 13, 46
			D01475
			D02290
			D00126	Ibuprofen	[6] 13, 46, 65, 113, 271, 299
			D01122
			D04490
			D06606
			D00118	Naproxen	[3] 13, 46, 271
		[1] VEGFA	D06409	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331
206	Viral carcinogenesis 6 genes, 1 drug (DrugBank), 4 diseases shown	[6] HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G	D04318	Glatiramer	[4] 2, 13, 96, 156
207	Viral myocarditis 24 genes, 4 drugs (DrugBank), 37 diseases shown	[1] ABL1	D01441	Imatinib	[11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162
			D08066
		[2] CD80, CD86	D03203	Abatacept	[24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300
		[20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G	D04318	Glatiramer	[4] 2, 13, 96, 156
		[1] ITGAL	D03959	Efalizumab	[9] 11, 13, 37, 46, 49, 53, 61, 95, 96
208	Viral protein interaction with cytokine and cytokine receptor 2 genes, 2 drugs (DrugBank), 22 diseases shown	[1] IL2RA	D03639	Daclizumab	[7] 13, 56, 60, 65, 97, 283, 284
		[1] IL6R	D02596	Tocilizumab	[16] 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331
209	Wnt signaling pathway 6 genes, 2 drugs (DrugBank), 30 diseases shown	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2	D00107	Tacrolimus	[30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299
			D08556
		[1] PSEN1	D09010	Tarenflurbil	[1] 13
210	Yersinia infection 1 gene, 2 drugs (DrugBank), 6 diseases shown	[1] ITGA4	D06590	Firategrast	[1] 13
			D06886	Natalizumab	[6] 13, 15, 25, 46, 63, 96