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 Target Gene/Pathway 

   e.g. "Sirolimus", "Adalimumab", "MAP2K"

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80 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY * 
 On map, Yellow: Drug target, Red: Disease-related 		  KEGG GENES * 
 [Number of genes] 		  KEGG DRUG *   DrugBank   Disease ID * 
 [Number of diseases] 
 1  Adipocytokine signaling pathway 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 2  African trypanosomiasis 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 3  AGE-RAGE signaling pathway in diabetic complications 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 4  Allograft rejection 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 5  Alzheimer disease 
 6 genes, 2 drugs (DrugBank), 38 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 6  Amoebiasis 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 7  Amphetamine addiction 
 5 genes, 1 drug (DrugBank), 30 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 8  Amyotrophic lateral sclerosis (ALS) 
 6 genes, 2 drugs (DrugBank), 38 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 9  Antifolate resistance 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 10  Antigen processing and presentation 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 11  Apoptosis 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 12  Asthma 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 13  Axon guidance 
 5 genes, 1 drug (DrugBank), 30 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 14  B cell receptor signaling pathway 
 5 genes, 1 drug (DrugBank), 30 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 15  C-type lectin receptor signaling pathway 
 6 genes, 2 drugs (DrugBank), 38 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 16  Calcium signaling pathway 
 5 genes, 1 drug (DrugBank), 30 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 17  Cellular senescence 
 5 genes, 1 drug (DrugBank), 30 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 18  cGMP-PKG signaling pathway 
 5 genes, 1 drug (DrugBank), 30 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 19  Chagas disease (American trypanosomiasis) 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 20  Cytokine-cytokine receptor interaction 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 21  Dilated cardiomyopathy (DCM) 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 22  Dopaminergic synapse 
 3 genes, 1 drug (DrugBank), 30 diseases shown 		  [3] PPP3CA, PPP3CB, PPP3CC   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 23  Epstein-Barr virus infection 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 24  Fc epsilon RI signaling pathway 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 25  Fluid shear stress and atherosclerosis 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 26  Glucagon signaling pathway 
 5 genes, 1 drug (DrugBank), 30 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 27  Glutamatergic synapse 
 5 genes, 1 drug (DrugBank), 30 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 28  Graft-versus-host disease 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 29  Hematopoietic cell lineage 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 30  Hepatitis B 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 31  Hepatitis C 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 32  Herpes simplex virus 1 infection 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 33  Human cytomegalovirus infection 
 6 genes, 2 drugs (DrugBank), 38 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 34  Human immunodeficiency virus 1 infection 
 6 genes, 2 drugs (DrugBank), 38 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 35  Human papillomavirus infection 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 36  Human T-cell leukemia virus 1 infection 
 6 genes, 2 drugs (DrugBank), 38 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 37  Hypertrophic cardiomyopathy (HCM) 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 38  IL-17 signaling pathway 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 39  Inflammatory bowel disease (IBD) 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 40  Influenza A 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 41  Insulin resistance 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 42  Kaposi sarcoma-associated herpesvirus infection 
 5 genes, 1 drug (DrugBank), 30 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 43  Legionellosis 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 44  Leishmaniasis 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 45  Long-term potentiation 
 5 genes, 1 drug (DrugBank), 30 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 46  Malaria 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 47  MAPK signaling pathway 
 6 genes, 2 drugs (DrugBank), 38 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 48  mTOR signaling pathway 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 49  Natural killer cell mediated cytotoxicity 
 6 genes, 2 drugs (DrugBank), 38 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 50  Necroptosis 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 51  NF-kappa B signaling pathway 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 52  NOD-like receptor signaling pathway 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 53  Non-alcoholic fatty liver disease (NAFLD) 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 54  Oocyte meiosis 
 5 genes, 1 drug (DrugBank), 30 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 55  Osteoclast differentiation 
 6 genes, 2 drugs (DrugBank), 38 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 56  Oxytocin signaling pathway 
 5 genes, 1 drug (DrugBank), 30 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 57  Pathogenic Escherichia coli infection 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 58  PD-L1 expression and PD-1 checkpoint pathway in cancer 
 5 genes, 1 drug (DrugBank), 30 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 59  Pertussis 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 60  Proteoglycans in cancer 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 61  Renin secretion 
 5 genes, 1 drug (DrugBank), 30 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 62  Rheumatoid arthritis 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 63  RIG-I-like receptor signaling pathway 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 64  Shigellosis 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 65  Sphingolipid signaling pathway 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 66  Systemic lupus erythematosus 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 67  T cell receptor signaling pathway 
 6 genes, 2 drugs (DrugBank), 38 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 68  TGF-beta signaling pathway 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 69  Th1 and Th2 cell differentiation 
 5 genes, 1 drug (DrugBank), 30 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 70  Th17 cell differentiation 
 5 genes, 1 drug (DrugBank), 30 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 71  TNF signaling pathway 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 72  Toll-like receptor signaling pathway 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 73  Toxoplasmosis 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 74  Tuberculosis 
 6 genes, 2 drugs (DrugBank), 38 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 75  Type I diabetes mellitus 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 76  Type II diabetes mellitus 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 77  VEGF signaling pathway 
 5 genes, 1 drug (DrugBank), 30 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 78  Viral protein interaction with cytokine and cytokine receptor 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 79  Wnt signaling pathway 
 5 genes, 1 drug (DrugBank), 30 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 80  Yersinia infection 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 

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